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Pentasa and Headaches: What Users Say

Headaches: mentioned by 4 users (4.5%)

Based on user experiences from 89 Pentasa reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

diarrhea 9.0%
hair loss 9.0%
cramps 6.7%
chest pain 4.5%
headaches 4.5%
heart palpitations 4.5%
severe pain 4.5%
bleeding 3.4%
nausea 3.4%
upset stomach 3.4%

Reviews for Pentasa

Commonly mentioned side effects
  • Vit...
  • Taken for less than 1 month
  • June 23, 2016

For Ulcerative Colitis "Age 37, diagnosed with bad UC at 12, recent years only flares up 2-3 times/year. Currently fighting the first bout of the year with Pentasa suppositories, taking 1-2/day. Has stopped the bleeding and going less frequently BUT awful headaches (as with Asacol/Salofalk foam enemas). Note to self/others who are sick of drugs: I have found (25 yrs in) that it IS possible to be symptom-free if you properly and consistently take care of yourself. This means plenty of rest/sleep, chamomile tea/water, gentle exercise, meditation (mindfulness is a cliché/buzzword but there's a lot to it), steamed veggies/rice, avoiding sugar/alcohol/dairy/caffeine (going gluten-free can help some people too)... I intend to cure myself completely one of these days!!"

6 / 10
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28 Report
  • Anonymous
  • September 29, 2011

For Ulcerative Colitis, Active "I took Pentasa for ulcerative colitis after Asacol started failing. Asacol had worked for me for seven years, but when P&G started having manufacturers make it in Europe, it no longer worked. The Pentasa worked for my ulcerative colitis at a 3-gram per day dosage. The side effects are much worse for Pentasa. I experienced nausea, mild headaches, and severe hair loss."

6 / 10
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30 Report
  • red...
  • December 26, 2009

For Crohn's Disease, Maintenance "My husband has only been taking Pentasa for a few days, but he has had terrible side effects since day one. His Crohn's had become progressively worse over the years, so his GI doctor prescribed Pentasa. He has chest pains, headaches, severe nausea and vomiting, as well as loss of appetite. I saw that one person had to lower his dose after 3 weeks, and I wonder if that was due to his experience of these effects also. I know Pentasa has great potential, but how long will these effects last?"

5 / 10
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24 Report

Frequently asked questions

  • Ama...
  • April 2, 2016

For Ulcerative Proctitis "I've been using Pentasa 2 times a day, a total of 4 pills. It definitely helps! Sometimes I get headaches and feel sick, and sometimes I occasionally get pain, and for some reason, ever since I started taking them, I get these weird skin patches."

9 / 10
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9 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.