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Pentasa and Cramps: What Users Say

Cramps: mentioned by 6 users (6.7%)

Based on user experiences from 89 Pentasa reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

diarrhea 9.0%
hair loss 9.0%
cramps 6.7%
chest pain 4.5%
headaches 4.5%
heart palpitations 4.5%
severe pain 4.5%
bleeding 3.4%
nausea 3.4%
upset stomach 3.4%

Reviews for Pentasa

Commonly mentioned side effects
  • Deb...
  • January 3, 2021

For Ulcerative Colitis "Received a diagnosis last year of ulcerative colitis when I stopped smoking. Two months later, all the symptoms hit: bloated, pains in the stomach, constipation, and lots of blood! I went for a colonoscopy and was diagnosed with ulcerative colitis. At first, I was given the rectal foam... I found the process awful, once inserted, you couldn’t move, otherwise it triggered a bowel movement and also caused awful cramps. I then tried the Pentasa tablets, taking 2 a day for 8 weeks now, and what a difference! The bloating and pain in the stomach has gone down loads, bowel movements are more regular, and much less bleeding. I still get the odd niggly feelings and a small amount of blood, so the doctor has recommended upping the dose to 4 a day. So far though, these tablets have massively improved my ulcerative colitis. I’m in the UK and fortunate enough to have the NHS, so I pay £9 for three big boxes. It’s crazy to think people have to pay hundreds for no fault of their own!"

8 / 10
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  • Gor...
  • November 2, 2016

For Crohn's Disease, Maintenance "I'm a 47-year-old male and have had Crohn's now for 17 years. I've been taking one sachet of Pentasa in the morning after breakfast. I realize I'm pretty lucky as I lead a normal life, enjoying a pint or two with a curry, etc. My only issue from time to time is painful cramps from my back passage, this happens during the night and can last anywhere between 15 minutes to an hour. This happens maybe once every 2 months. I have not had any surgery, so I'm very grateful for Pentasa, as it seems to keep my Crohn's at bay. I'm from Scotland and get my medication prescription free."

9 / 10
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33 Report
  • Juv...
  • November 20, 2017

For Crohn's Disease, Maintenance "I'm a Filipina, 44 years old, and was diagnosed with Crohn's in 2014. I've been taking Pentasa tabs and suppositories as well. My first 6 months were four Pentasa 500 mg tablets twice a day and 1 suppository before bedtime. There was an improvement, I had less diarrhea and cramping of the stomach. I maintained taking Pentasa for 2 years and reduced the dosage until I took two 500 mg Pentasa a day and 1 suppository. Since I feel better, I decided to stop taking the medicine. Now I'm 3 years without taking any medicine and starting again with diarrhea and bloody stools. Maybe I need to start back on Pentasa again."

9 / 10
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21 Report

Frequently asked questions

  • wal...
  • October 27, 2015

For Crohn's Disease, Maintenance "I have started the Pentasa. It has given me diarrhea and some stomach cramps when taking it. I have to see if after taking it for a week how it will do with the Crohn's or see about getting off of it. I am also getting cramps in the stomach area when taking this medication."

4 / 10
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  • cro...
  • Taken for 10 years or more
  • August 12, 2024

For Crohn's Disease, Maintenance "I have had a good experience with Pentasa. I have been on 4g a day for the last 10 years for Crohn's disease. I don't think I have any major side effects. I have been in remission, blood and scope wise, for years. I do have some symptoms, like cramps and upset stomach every now and then, and have to pace myself sometimes, but overall I'm happy with it. It's not completely perfect symptom wise, but I can live a decent life with it, so all good."

8 / 10
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  • mn ...
  • Taken for less than 1 month
  • December 23, 2012

For Crohn's Disease, Maintenance "I have been on Pentasa, 2 capsules 2x a day. First week, feel amazing to not have all-day tummy pain or cramping. Hope I have found something that will continue to work for me."

10 / 10
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34 Report

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