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Mesalamine User Reviews & Ratings (Page 2)

Brand names: Lialda, Pentasa, Asacol, Apriso, Asacol HD, Delzicol, Canasa, Rowasa, Zaldyon Canasa Pac Rowasa Sulfite Free …show all brand names

Mesalamine has an average rating of 7.1 out of 10 from a total of 420 reviews on Drugs.com. 62% of reviewers reported a positive experience, while 20% reported a negative experience.

Reviews for Mesalamine

  • Gear
  • July 19, 2018

For Ulcerative Colitis, Active "Been on this for two months now, absolutely no more. Its terrible. Makes my symptoms worse. I keep being told not to stop taking it, the effects will eventually stop, they don't. Abdominal pain, in areas I've never felt before now not just my lower left side but all the way up under ribs. Terrible swelling, nausea, headaches, dizziness, fatigue, general sick feeling, constipation, bloating, pain every time i eat. I'm stopping this now. It's not helping and even if it did, side effects outweigh the benefit. I was better before starting this rubbish."

1 / 10
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  • mareyj
  • January 20, 2015

Pentasa (mesalamine) for Crohn's Disease, Maintenance "I am 67 years old and was diagnosed with Crohns at age 50. I have taken Pentasa for 16 years. I took 4x250mg three times daily and experienced chest pains. I cut it to 3x250x3times daily and that took care of the chest pains. I am a fairly petite woman so that could be a factor. I have had flare-ups but generally have done great. I tired cutting back myself and each time had severe pain, vomiting etc. I now know not to cut back. I hope to continue on Pentasa."

10 / 10
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  • Natur...
  • Taken for less than 1 month
  • January 17, 2017

Lialda (mesalamine) for Ulcerative Colitis, Active "I was prescribed this med for mild UC. I discussed concerns with my doctor on starting a medication while nursing and without trying natural approach to curing the symptoms first. He share some patience had success using turmeric supplement to address inflammation of the sigmoid colon (lower intestine and bowel). After 2 weeks on the Turmeric my symptoms of urgency, cramping and excessive frequency to 'go' subsided. After 3 weeks, I've been having normal bowel movements and no cramping. I am happy with the progress I've made on this natural remedy."

1 / 10
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Frequently asked questions

  • KeenK...
  • Taken for 1 to 6 months
  • March 20, 2015

Lialda (mesalamine) for Ulcerative Colitis, Active "I have fairly severe Ulcerative Colitis & after 4 months of feeling horrible, tired, bloody diarrhea with the constant urge to go & fear of eating & setting it off again I was finally diagnosed & put on Lialda - 4 pills once a day. At first it caused horrible gas & bloating & took about a week or so to help the symptoms at all but after a few weeks the symptoms were completely gone & the side effects went away as my body got used to the medication. Then about 1 month into taking it I developed horrible cystic acne all over my face, neck, chest, even in my nostrils & ears! My Dr cut the dose in half to 2 pills once a day & within a few days my skin started to clear & heal. I have been on the lower dose for about a month with NO PROBLEMS!!"

9 / 10
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  • J Mcc...
  • June 19, 2013

Pentasa (mesalamine) for Crohn's Disease, Maintenance "Was diagnosed about 1 year after an emergency surgery for a mass in my colon due to a build up of scar tissue from inflammation. After a couple months of 500mg 3X a day frequency of flare ups were greatly reduced. Only had 2 noticeable symptoms, one of weight gain and an an elevated liver function test. My dosage was reduced to 2X a day and liver function is normal but weight gain is still issue. Diet and STRESS level seems to be the most important factor in controlling flare ups"

8 / 10
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Are you taking this medicine?

  • Chuck
  • Taken for 10 years or more
  • July 12, 2019

For Ulcerative Colitis, Maintenance "I was diagnosed with Ulcerative Colitis in 2007. I was originally put on 4.8 gm/day of mesalamine. After a year on it my colitis was non-detectable and I was put on 2.4 gm/daily for maintenance. I've been taking this medication for over 10 years now with no complications or side effects. I've have had occasional flare-ups and simply increased the dosage back to the original 4.8 gm/daily until the symptoms cleared (usually within a week). My last colonoscopy in 2018 also showed no signs of the colitis. I've had very good results with this medication."

10 / 10
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  • ddive
  • February 6, 2011

Lialda (mesalamine) for Ulcerative Colitis, Active "I had been in remission for 20 years and then had a flair up like never before. I refuse to take any steroid based medicines due to the side effects and advised my Doctor of that. He started me on 4 pills of Lialda a day and within 1 week all of my symptoms where gone. I am now taking 2 pills a day and remain symptom free with absolutely no side effects. "

10 / 10
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  • Anonymous
  • October 3, 2010

Asacol (mesalamine) for Ulcerative Colitis, Maintenance "I've had ulcerative colitis now for 28 years. I took Asacol during all my three pregnancies with no side effect. I did have a major flare-up after the first delivery though despite the Asacol. My ulcerative colitis is now completely under control, so much so that my doctor said that my colon looks completely healthy. I take 4 tablets per day, I do forget occasionally, but it has worked miracles for me. I can also eat everything."

10 / 10
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  • Wewil...
  • Taken for 10 years or more
  • August 27, 2018

Pentasa (mesalamine) for Crohn's Disease, Maintenance "I am unable to purchase my pentasa 500 Mg that I have been taking affordably for over 30 years. The Affordable Health Care Act we have today is very misleading. The price went from $300.00 for 90 day to $1,556.00 for the same. Please Americans are suffering without their meds!!!!"

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  • Jerbons
  • Taken for 2 to 5 years
  • September 16, 2012

Asacol (mesalamine) for Ulcerative Colitis, Maintenance "I have been on Asacol, two 400mg pills three times a day. It has done wonders for me. I have no side effects at all and it has kept my ulcerative colitis in remission with to symptoms at all. While my doctor has told me to stay on the full dosage, the bottle says that after 6 weeks one should go on maintenance of only 4 pills per day. Due to the expense of these pills, I am already down to 5 pills per day and still doing great."

10 / 10
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  • Stephen
  • Taken for 2 to 5 years
  • December 30, 2023

Pentasa (mesalamine) for Ulcerative Colitis "I have had left side colitis since my return from Vietnam in 1970. I have been in and out of the hospital, put on Prednisone so many times, every drug imaginable over the years… Five years ago I had one of my twice yearly bad flares and my Dr. put me on 8 500mg tablets every day. It has been a miracle for me. In remission for 5 years. No side effects. I’m 78 years old, so I have had this a long time. The only negative side is trying to swallow those horse pills… my advice to my fellow sufferers is don’t give up! One last thing… I moved to Costa Rica with my wife 13 years ago. I belong to Caja which is the country's socialized medical system. It covers all the cost of the drug."

10 / 10
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  • SUZIE...
  • September 20, 2019

Asacol (mesalamine) for Ulcerative Colitis "I have had colitis for 20 years. I was prescribed steroids but did not want to take them. I had gas, bloating loose watery foul smelling bowel movements. Up to 20 a day. I started on Asacol 800mg. I took 6 tabs a day. Two in the morning, 2 mid day and 2 at bedtime. I saw no results and was even passing whole tablets...as I know it is common. I almost threw in the towel. At the 3 month mark I had formed stools, and minimal gas and bloating. You have to be patient. Our bowels did not get sick overnight...so you are not going to be cured overnight. 20 years of issues took about 3 months on Asacol. Now I am down to 2 x 800mg tabs maintenance dose. 1 tab in the morning and 1 tab at night. I still have the odd loose bowel movement if I eat greasy food or drink too much coffee. But all and all..well worth it."

8 / 10
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  • sick...
  • Taken for 1 to 2 years
  • September 8, 2017

Lialda (mesalamine) for Ulcerative Colitis, Active "I was on asacol for 10 years with no flare ups and leading a normal life. Then 2 years ago my insurance (BCBS) stopped covering it. My Doctor changed me to Lialda and I have had a nothing short of continuous colitis hell flare up for 2 years straight. 20 diarrheas a day. Stomach cramps, weight loss, explosive uncontrolled bm. My Doctor refused to write a letter of medical necessity to my insurance company so I could get back on asacol. So I was on continuous steroids which caused diabetes. Finally to the point of starting humira which caused e coli, c diff, nor ovirus. Recent hospitalization which I was able to get back on asacol while in the hospital. Now discharged and unable to get asacol approved for use outside of hospitalization. "

1 / 10
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  • Mark...
  • May 20, 2017

Pentasa (mesalamine) for Crohn's Disease, Maintenance "I've been taking Pentasa for several years. I remember vividly having to go to the bathroom several times a day. I have to go just once a day, maybe once every other day since taking Pentasa. My dosage is two 500 mg capsules four times a day. The only side effect I have experienced is passing gas considerably."

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  • Hotmo...
  • January 28, 2014

Pentasa (mesalamine) for Crohn's Disease, Maintenance "I was diagnosed in 2013 with Crohns. Pentasa has relieved my symptoms greatly. I take 500 mg 4 times a day. I find it works better for me when I take it with food. My only side effect is night quivers. Other than this, Pentasa works wonders. It's well worth my $55 copayment each month."

10 / 10
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  • In...
  • July 12, 2013

Lialda (mesalamine) for Ulcerative Colitis, Active "I have Ulcerative Colitis and have been on Lialda for a few years, 4 pills per day. I am in remission. My biggest problem is Urgency and if I can conquer this problem I would be so much better. I have no pain. I eat most foods but stay away from gassy foods such as beans. I found that when I eat popcorn, I have problems. "

7 / 10
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  • DownW...
  • Taken for 1 to 6 months
  • April 14, 2019

For Ulcerative Colitis, Maintenance "Mesalamine did absolutely nothing for me but I’m sure it put some extra money into my doctor’s pocket. I told my sister (who is a teacher) about my colitis and the medication the doctor put me on. She told me to drink dandelion root tea because it’s a probiotic.... CLEARED IT UP COMPLETELY IN ABOUT A WEEK AND A HALF. I drank it everyday during that time. I had been bleeding for a whole year before the tea (even during the lialda)."

1 / 10
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  • Anonymous
  • September 17, 2011

Lialda (mesalamine) for Ulcerative Colitis, Active "What a remarkable medicine. I had battled with ulcerative colitis for quite a few years before I decided to FINALLY go to a G.I doctor. I am so glad I did because after my diagnoses I began Lialda and it has been heaven sent. I can now live a normal life, not "fearful" of foods and how they may affect me later. I had quite a few other symptoms (cramping, moderate bleeding, etc) and sure enough they have all been relieved. I take 2 tablets twice a day and have had no side effects :) Or at least not any that I have noticed. I am relieved to know that my future looks brighter, because being in my younger 20's and dealing with this health issue wasn't exactly the most pleasant thing."

10 / 10
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  • Sugar
  • Taken for 10 years or more
  • September 30, 2018

Lialda (mesalamine) for Ulcerative Colitis "Lialda put me in remission for over 12 years. I never experienced any side effects, until a few months ago when Lialda almost killed me. It gave me pancreatitis. My lipase was at 10,000, the normal is 0 to 90. I am extremely lucky."

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  • Anony...
  • June 25, 2015

Lialda (mesalamine) for Ulcerative Colitis, Active "I was diagnosed with left-sided UC in May of 2015. My GI prescribed 4.8 grams (4 pills in the am) of Lialda, plus 1 Canasa suppository (1 gram) at night. The suppository was for 3 weeks only. Within 2 weeks, the bleeding stopped, and I no longer saw the remnants of the colon tissue erosions when I had a bowl movement. I stopped taking the Canasa after a week and a half, because I think it was leading me towards diarrhea, and I felt slight rectal pain. There was no noticeable negative effect to me stopping the Canasa dose at that point. I continued to take the regular dosage of Lialda. I had some dizziness the first week or two, but that had since abated. I also noticed acne that I haven't had in many years. No issues with hair thinning."

8 / 10
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  • Gordon...
  • November 2, 2016

Pentasa (mesalamine) for Crohn's Disease, Maintenance "Hi I'm a 47 year old male and have had crohn's now for 17 years. I've been taking one sachet of pentasa in the morning after breakfast. I realise I'm pretty lucky as I lead a normal life, enjoying a pint or to with a curry etc. My only issue from time to time is painful cramps from my back passage, this happens during the night and can last anywhere between 15 mins to an hour, this happens maybe once every 2 months. I have not had any surgery so I'm very greatful for pentasa as it seams to keep my Crohn's at bay. I from Scotland and get my medication prescription free."

9 / 10
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  • Fiona...
  • Taken for 5 to 10 years
  • March 12, 2013

Pentasa (mesalamine) for Crohn's Disease, Maintenance "I take 1000 mg 2x day along with Humira every two weeks. The combination works very well for me and I'm healthier than I've been in years. The only significant side-effect for me has been anxiety. I am told it is not a side effect but I've been off and on Pentasa over the years and the 3 years stretch where I was off completely, my anxiety went away entirely. It wasn't until I went back on Pentasa that I made the connection."

8 / 10
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  • Doing...
  • Taken for 1 to 2 years
  • April 5, 2017

Lialda (mesalamine) for Crohn's Disease "Ok not enough room on this review to put up my full history. So will be brief. :) So far, tried Asacol and Humira and both did nothing for me. Now I am on Lialda twice a day, 1.2GM tablets. And these are working great. No cramps and limiting me now to about 2 - 3 bowel movements a day. And no bloody stools unlike my past. (10 years diagnosis). I have also changed my diet to a Mediterranean diet with little to no red meat. Mainly chicken and fish for my sources of protein. No deep fried foods. And has worked out great. Also for veggies/greens etc, skip out on any gas producing vegs (broccoli and onions for example). And taking vitamins/iron supplements daily to keep those well maintained."

10 / 10
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  • sir...
  • October 18, 2011

Lialda (mesalamine) for Ulcerative Colitis, Active "I've been using Lialda on and off for about 2 yrs now. Used it daily when 1st prescribed until all ulcerative colitis symptoms went away. I mainly use it during flare ups. My Colitis began severely flaring up this past week and since I started taking Lialda again, I notice reduction/elimination of blood in stool, less bowel movements and more solid movements. I believe Lialda is extremely helpful, especially if taken as maintenance medication to prevent flare ups...which is what I should start to do."

8 / 10
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  • Anonymous
  • February 26, 2012

Apriso (mesalamine) for Ulcerative Colitis "I would probably rate Apriso higher if it were not for some side effects. The only medicine that has actually worked to keep the blood and unreal cramps at a distance. It works. only twice have I had symptoms since 11/01/2011, I hope it stays that way. Anyone with ulcerative colitis know's how important this is."

8 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.