Nucala and Tiredness: What Users Say

• Str...
• Taken for 1 to 6 months
• January 10, 2020

For Asthma "I have now had my second injection of Nucala. I was so happy with the results of no runny nose, chest congestion was much better. I also have a back problem and have had one hip replacement surgery and am waiting for the second one. I take maintenance medications for pain management. I started with pain so bad, my joints ached, my skin hurt, I was so tired, and got exhausted just going to town and trying to get groceries. I stay on my heating pad day and night. I am up and down frequently, my pain meds are not working well. I made an appointment to go back to the doctor and see what can be done. I liked the results of the Nucala and what it does for my breathing. Anyone have any ideas?"

• Str...
• Taken for 1 to 6 months
• January 10, 2020

For Asthma "I have now had my second injection of Nucala. I was so happy with the results of no runny nose, chest congestion was much better. I also have a back problem and have had one hip replacement surgery and am waiting for the second one. I take maintenance medications for pain management. I started with pain so bad, my joints ached, my skin hurt, I was so tired, and got exhausted just going to town and trying to get groceries. I stay on my heating pad day and night. I am up and down frequently, my pain meds are not working well. I made an appointment to go back to the doctor and see what can be done. I liked the results of the Nucala and what it does for my breathing. Anyone have any ideas?"

• Pjb...
• Taken for 1 to 6 months
• February 25, 2022

For Hypereosinophilic Syndrome "Just received my 3 shots (300 milligrams) and administered it at home. After working with my doctors. My eosinophils have gone down. But the tiredness, back pain, and headaches are horrible. Time will tell if this will be worth it. Totally off prednisone after years of taking it. Unfortunately, severe osteoporosis from the prednisone. Age 57."

• Anonymous
• Taken for 6 months to 1 year
• December 26, 2020

For Asthma "I have been taking Nucala for 9 months. I have severe persistent eosinophilic asthma. My asthma had a rapid onset and began about 2 years ago. I was completely healthy prior. I was using a nebulizer every 2-3 hours around the clock and on 02 at 3-5L because my airways were so tight. 10 days after the first injection, I was no longer requiring oxygen or neb treatments. Over the course of treatment, I've had a few minor setbacks, but they've been small in comparison to what I was living prior. The first couple of months, I had bad headaches and some backaches, but both resolved with ibuprofen. I get tired and flu-like at times, but a short rest usually takes care of that. I have minor skin issues, and my hair has thinned a bit, but those are things that I'm willing to deal with to have my life back. I can take my grandbaby on walks in her stroller and not be gasping for air. Nucala has been life-changing for me."

• ter...
• Taken for 1 to 6 months
• April 17, 2023

For Eosinophilic Granulomatosis with Polyangiitis "Where do I start? I was fine until I took Nucala. My PSA immediately doubled, my blood pressure went up, I had debilitating back and shoulder pain, my bowels got clogged up, I was tired, and I had abdominal pain. In short, the stuff was poison to me. All these issues that came up I never had until Nucala. NONE of them. I am now off Nucala, but my back still won't heal and is very painful. Be careful what you take and what you believe about these biologics. You could not pay me to take Nucala!!"

• Wee...
• Taken for 2 to 5 years
• February 5, 2021

For Asthma "I had an allergic reaction to Xolair and have been on Nucala for about 3 years now. I always got headaches, felt tired a day or two after I received the injection, but today was different. I got the injection Wednesday, today is Thursday, and when I got home, I wasn't feeling good, real tired, short of breath, my heart was racing, itchy throat, pain in my shoulder and up my neck where I received the shot, which I usually feel, chest is sore and my oxygen was 92-93. I went to the ER, and the doctor told me not to get the injection anymore. He did a chest x-ray and gave me breathing treatments. The injection really gave me a better quality of life, but I am scared to get it again, unsure what to do. My pulmonologist is supposed to call me back Saturday and we're supposed to talk about getting the injection again or not. With Xolair, he said I could die if I get it again, so of course, I said no, I don't want it. Has anyone else experienced this, getting Nucala?"

• EDa...
• June 3, 2019

For Asthma "Nucala works as intended, keeping me from very bad exacerbations. Side effects are a bit tough for me, as I feel tired and experience flu-like symptoms. I tend to get more chest infections, like 6 a year vs. 1 a year. Maybe it's the medicine interaction in my lungs causing more sensitivity to the cold. I guess that's better than the alternative emergency room visit due to severe asthma."

• Anonymous
• Taken for 2 to 5 years
• February 24, 2023

For Eosinophilic Granulomatosis with Polyangiitis "I have Churg-Strauss and have been hospitalized three times before being diagnosed. This drug has saved my life, if only not having to take prednisone. Dosage I have taken for almost three years is 300 ml every 28 days, with no negative side effects. Blood tests reveal no eosinophils at the end of four weeks, and I always feel much better after the injections. Sometimes I get tired after the injections, but I don’t consider it a negative."

• Hea...
• Taken for 1 to 2 years
• October 12, 2024

For Chronic Rhinosinusitis With Nasal Polyps "I have suffered with sinusitis and nasal polyps for many years, and diagnosed with mild asthma (in my late 60s). Have had no sense of smell for 10 years. After 3 sinus surgeries, I was approved for Nucala 16 months ago. Within 2 weeks, my sinuses were clear, asthma improved, and sense of smell slowly returning. Now, I only use my asthma puffer once a week (previously twice daily) and sinuses so good I can easily breathe through my nose. And now I have full sense of smell after 10 years. The only side effect is I get tired, but part of that could be age as I am in my 70s, still working and quite active. Nucala has definitely worked for me - hope to still be having the same result for a few more years."

• Hap...
• Taken for 1 to 2 years
• March 11, 2025

For Chronic Rhinosinusitis With Nasal Polyps "I have been on Nucala for 20 months, specifically for my sinusitis. Also had mild asthma and no sense of smell after my 3rd sinus surgery a few years ago. For me, this medication is a miracle, within a week, my sinuses were clear and asthma under control. I am now at the stage where my sinuses still clear, don't need my Symbicort for asthma, and my smell is restored. The only side effect is tiredness (but that could be age-related - 77). I will continue with Nucala, for me, it's a wonder injection and so easy once a month."