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Tirosint and Headaches: What Users Say

Headaches: mentioned by 9 users (6.4%)

Based on user experiences from 140 Tirosint reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

hair loss 12.9%
fatigue 9.3%
weight gain 9.3%
anxiety 8.6%
insomnia 8.6%
heart palpitations 7.1%
headaches 6.4%
chest pain 5.7%
pain 5.0%
swelling 5.0%

Reviews for Tirosint

Commonly mentioned side effects
  • Jai...
  • Taken for less than 1 month
  • March 29, 2019

For Underactive Thyroid "I was on a low dose for 2 weeks and developed a rash and sore throat. I thought it was a virus. After 2 more weeks, I developed a severe headache, neck pain, and dizziness. Stopped the medication 5 days ago and am still having issues, but the severe headache is less. Not sure how long it will be before it is all out of my system."

1 / 10
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  • sor...
  • Taken for 1 to 6 months
  • May 4, 2019

For Hypothyroidism, After Thyroid Removal "I loved it for the first month. Then, I developed agonizing headaches and chest pains. Had to go to the ER four times in pain. They could not do anything. Seven months later, I am still in pain and have to go to a gastro specialist to find out what is wrong in my stomach. It is really scary. I think it gave me some kind of ulcers in my stomach."

1 / 10
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  • 178...
  • Taken for less than 1 month
  • February 11, 2018

For Hashimoto's disease "I had been on Synthroid for over 10 years for hypothyroidism. I was then diagnosed last year with Hashimoto's. I felt like the Synthroid was no longer working for me. I saw a new endocrinologist who gave me samples of Tirosint. I am a migraine sufferer and have been for years. I started getting headaches with the Tirosint that were different from my migraines. Not even two weeks after starting Tirosint, I had a headache so bad I could not stop puking. I ended up at the ER. As they started an IV and pain/nausea meds, they told me they needed to admit me to ICU. My heart rate was 166, and I was in AFIB. I have never had heart problems in my life, and there is no history in my family. Luckily, the drugs they were giving me in my IV put my heart back in rhythm, or they were going to have to stop/restart my heart. Once released from the hospital, I never took Tirosint again and went back to Synthroid. I am now permanently on Cardizem and an aspirin a day."

1 / 10
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42 Report

Frequently asked questions

  • Jac...
  • Taken for less than 1 month
  • February 27, 2020

For Hypothyroidism, After Thyroid Removal "I took my first dose of Tirosint in the morning, and within a half hour, my ears started ringing, and I got a bad headache. By the time it was bedtime, I felt so nervous and shaky that I never fell asleep. It was an awful experience. The next day, I went back to my Synthroid."

1 / 10
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32 Report
  • Lib...
  • October 9, 2016

For Hashimoto's disease "I was on levothyroxine for 10 years, and it never did anything for me. My levels were never optimal, and I continued to gain weight, be depressed, and waste money on a useless drug. So far with the Tirosint, my only side effect is a slight headache. For the first time in my life, my hormone levels are excellent, but my wallet is empty. Tirosint is ridiculously expensive. I use a compounding house that sells a month's supply to me for $68 (Willow), as opposed to the $125 per month that CVS wanted. I feel the price is a disgrace, and something needs to be done about this. I have insurance that does not cover this drug (BCBS). My doctor gave me a discount coupon for $35 a month, but Blue Cross Blue Shield would not honor it. Ask your doc for this."

7 / 10
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43 Report

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  • Bel...
  • Taken for less than 1 month
  • January 26, 2017

For Underactive Thyroid "My doctor switched me on Monday to Tirosint from levoxyl, and after 4 days, I'm going back to my old medicine, and I thank God I still have some because I can't go another day with these headaches, fatigue, and muscle aches. I've been on levoxyl, Synthroid, and levoxyl, and none have made me feel this horrible. I was planning on dealing with it to see if the symptoms would go away, but I work doing payroll and taxes, and this medicine is making me work really slow and making errors, so I don't have the luxury to wait and see if, in time, I feel better. What I don't understand, from what I've been reading, is that this is a more pure form of levoxyl, so if he's giving the same dosage, wouldn't it mean he's overmedicating me? I haven't talked to him yet."

1 / 10
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  • Lyd...
  • Taken for 5 to 10 years
  • July 3, 2018

For Underactive Thyroid "I've been on Tirosint for over 6 years now. I tried Synthroid and even Armour. Nothing worked until Tirosint. I started with 25 mcg and went up to 50 mcg and have been on 50 mcg like forever. My levels went from 14 to 8, then to 6, then to 4. Then I went back up to 8 and my doctor increased me to 75 mcg. Well, I thought I was going to die. The headaches, the fatigue, seeing spots, feeling dizzy, stomach discomfort, etc. Then some kind of lump developed on the right side of my neck. Like some kind of alien moving along my neck line & as it was happening, I called for my husband and said, 'What is that thing!!!!' So, I just put myself back on the 50 mcg and within 2 weeks felt better but not totally better. I think by increasing my med to 75 mcg was not a good plan by my doctor. I always say if it isn't broke, don't fix it!!!"

9 / 10
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More FAQ

  • AAa...
  • Taken for 6 months to 1 year
  • June 1, 2020

For Underactive Thyroid "I have had an underactive thyroid for 8 years. I could not handle Synthroid and was always going off. I like Tirosint, at first, I am only on a small dosage of 13, but my hair was falling out so badly that I started taking 2 pills during Corona because of no doctor. It stopped hair breakage, but if I take too much, I get headaches and have trouble sleeping. But now if I take 13 only, I get bad depression and my hair falls out again. Overall, I like the meds. I am diagnosed with Hashimoto's, and this is just my life-my own thyroid not being regulated. I have a bad headache today, so I can't take 2 tomorrow, so I guess I can prep for severe depression. Oy vey!"

9 / 10
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24 Report
  • Man...
  • Taken for less than 1 month
  • January 18, 2022

For Underactive Thyroid "I'll be switching to Tirosint most probably. The reason is that Mylan, which makes the generic Levothyroxine, has switched to using mannitol as the preservative. I've been getting headaches for weeks until I traced it to the mannitol and started using some pills for old bottles."

5 / 10
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10 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.