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Synthroid for Underactive Thyroid User Reviews (Page 2)

Synthroid has an average rating of 6.3 out of 10 from a total of 77 reviews for the treatment of Underactive Thyroid. 53% of reviewers reported a positive experience, while 32% reported a negative experience.

Reviews for Synthroid

  • Lucky...
  • August 30, 2016

"MUST be taken at night - and it absolutely seems to work for me. No more brain fog - and for someone who was always a go-getter - the brain fog was devastating. No more night sweats either. Those were the worst."

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  • Anonymous
  • Taken for 6 months to 1 year
  • March 30, 2015

"While it brought the TSH into the appropriate range, the exhaustion, lethargy, constipation, etc. was unbearable. For 20 hours out of the day, felt drowsy, unmotivated, and sleepy. This is no way to live. Got on Tirosint and what a difference."

3 / 10
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  • LoveN...
  • Taken for 6 months to 1 year
  • July 12, 2018

"Originally my doctor put me on Levothyroxine when I first had symptoms of hypothyroidism. I continue to have the symptoms and ended up putting on a total of 43 lb! I then asked to see an endocrinologist and Bug them to put me on nature thyroid.. do to my persistence they put me on 82. 75 MCG of naturethroid. After 3 weeks of it in my system, I began to have energy again, stomach aches went away, slept better and was able to work out daily again! My new endocrinologist insisted that Synthroid was better then nature thyroid... So I will switch to Synthroid.. stomach aches and fatigue came back.. Synthroid and Levothyroxine don't help."

3 / 10
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Frequently asked questions

  • Anonymous
  • June 8, 2010

"I've been on Synthroid (Levothyroxine) for about a year and a half now. They've changed my dose 4 times so far and I'm currently at 100 mcg. Once they keep me on a dose for a bit, I feel okay, but with every change I have a few annoying side effects. I can say that if you take it every day like you're supposed to, it will work eventually. You have to be patient; it won't make you feel great right away. It took me about 3 months. But it helped with my lethargy, weight, and even depression. It's pretty good if you take it as prescribed. If you stop taking it suddenly, the effects of hypothyroidism come back pretty quickly and severely, so I recommend taking it as your doctor states."

6 / 10
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  • Nanny...
  • January 23, 2016

"Before synthroid I was achy and tired. Now I have headaches...bloating...stomach pain...loose stools and the feeling of being in a fog. I'm only on day 4 of the lowest dose cut in half. I'm stopping it. I was put on it before and it made my heart go to sinus tach but the new doctor insisted I try it again! Hell no! I felt better before the medication!"

1 / 10
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Are you taking this medicine?

  • Strong...
  • Taken for 10 years or more
  • August 1, 2015

"Since being diagnosed with hypothyroidism in 1999. First, I was given antidepressants for being tired and gaining weight (eyeroll). I have been on 88mcg of Synthroid daily. My blood work has always come back with my TSH at the high end of normal. Former doctor retired years ago, so no continuum of care (walk-in clinic). Recently, a new doctor suggested we adjust meds to bring down the TSH level. Started with 100mcg of Levothyroxine 5 days & Synthroid 88 - 2 days a week. In a few months' time, I suffered some pretty severe side effects - extreme dizziness/weakness, lack of energy, mood extremes, weight is either climbing or stagnant, racing pulse/heart rate. We checked levels, and now TSH reads at the extreme low end of normal. I'm scared, please help."

3 / 10
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  • Kat_PK
  • Taken for 1 to 6 months
  • September 15, 2016

"I was taking Levothyroxin 50mcg for the past 3 months. My initial TSH was 13 when I started Levo; within 2 months, my TSH dropped to 2.5. Although my levels were normal, I continued to have some fatigue, sleepiness upon waking, night sweats, facial flushing, anxiety, and horrible brain fog. I decided to try my sample of Synthroid 50mcg and within a week, the brain fog, night sweats, and sleepiness were gone! I wake up with the most energy I have ever had! I am still experiencing some anxiety and facial flushing which we are monitoring, but overall Synthroid is working for me! I am 32 years old and 9 months postpartum. I also take my dose at night, hours after dinner."

8 / 10
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More FAQ

  • Anonymous
  • August 16, 2011

"The only confirmation I have that it works is my blood work. I feel no better or worse on Synthroid. It is very annoying to take. You have to take it in the morning, on an empty stomach, no food for an hour. And for some, no calcium for two hours. Tell me, how do you eat breakfast with this medicine!? It does work though, so I gave it an 8."

8 / 10
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  • Dennise
  • Taken for 1 to 6 months
  • October 16, 2017

"My doctor prescribed Levothyroxine for low thyroid and I had been feeling so tired and wiped out. Levothyroxine did help improve my numbers (TSH of 7.5 dropped to 4.5) but I felt awful on it. Everything hurt and I was so exhausted. After 3 months on Levothryoxine, I asked to try the brand name Synthroid. What a difference!!! It improved my numbers even more (same dose, TSH decreased to 1.75) and not only that, I felt better. I had energy. My experience is night and day. I know generics are supposed to be equivalent but I can tell you there is a difference. Synthroid brand works so much better than Levothyroxine. Recommended."

10 / 10
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  • AmyBill
  • August 13, 2016

"Diagnosed with Graves disease, my thyroid was radiated and destroyed. Put on synthyroid, took a while to get dosage right, but I have been on it for 8 years now and without it I would want to die. I take 100 mcg a day and I set my phone alarm to go off same time every day so I won't forget it."

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  • Teddy...
  • July 31, 2016

"I feel awful! I have been on this drug for 6 weeks. I have so many side effects. 1. Very tired (no energy). 2. Nausea. 3. Headache. 4. Can't sleep (even if I take a sleeping pill). 5. Always feel hot. 6. Sweating. 7. Clammy skin (have to have the fan on all the time). I live in Canada so it's not that hot. Never felt so sick."

1 / 10
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  • Anonymous
  • September 27, 2009

"I was born without a thyroid and I've been taking Synthroid every night. I'm only 13. I have to tell you this is the best thing ever. If I didn't have this medication, I would be barely alive. I wouldn't be this tall either (5'7). This medicine is my lifeline."

10 / 10
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  • Art
  • Taken for 10 years or more
  • August 21, 2018

"I have been on Synthroid for 12 years and I have had no side effects. I only have good things to say about this drug. However, when you start blood tests are essential to determine the right dosage. You must take on an empty stomach and no food for about an hour. Also, you need to keep the Synthroid level constant in your blood system. If you skip a day or two It is like you have to start over to get back to the dosage you were prescribed. This drug works. Use it as your Dr. tells you to and have blood tests on a regular basis."

9 / 10
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  • plinv...
  • October 25, 2009

"I have taken Synthroid for 23 years. The first 3 years I did okay on it but over the past 20, I started to feel lousy. I'm tired all the time and very irritable. I've taken from 0.050 MG to 0.125. I still feel bad. It's been adjusted at least 30 to 35 times throughout the course of 23 years. I feel totally helpless and hopeless. My doctor will not change my thyroid medication."

2 / 10
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  • Anonymous
  • February 20, 2012

"Have been taking thyroid medicines for 10 years. I found that the generic version is not absorbed as well as Synthroid. Went back to the brand name a few days ago and am no longer tired, and my period finally stopped after 3 continuous weeks. 10 on the scale for sure!"

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  • CatB
  • Taken for 10 years or more
  • November 27, 2020

"I have been on Synthroid since 1993. Prior to starting it, I couldn't lose weight no matter what I did. It was and is the help I needed. After being on Synthroid for about a decade, my insurance requested I switch to a generic. After a couple of months, my TSH levels were no longer balanced and my dose was increased. After nearly a year of no control, no matter what dose I was on, my levels and symptoms wouldn't stabilize. My doctor and I realized the change happened when I was switched to the generic. It took several months back on the Synthroid before I was stable again. No more generics for me, now it's my wallet getting lighter because of how expensive it is. But at least my levels are stable."

10 / 10
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  • Anonymous
  • July 3, 2008

"I have been taking Synthroid for about eight years now. I have tried the generic Levoxothyrine, and it makes me shaky all over even at the same dosage. My history has been going from hyperthyroid, caused by thyroiditis, to hypothyroid afterwards. I take my dose religiously every morning, 1 hour before breakfast. Even in light of this, I seem to have great fluctuations in my levels. I assume this is more a physiological problem than that of the medication. When we get it leveled out, I feel well."

8 / 10
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  • KFSI
  • April 13, 2011

"I have been on Synthroid for over 8 years and have actually gained weight. I have a very healthy lifestyle (exercise for one hour 5 days a week, and eat healthy), but nothing has been working. My endocrinologist consistently increases my prescription and nothing changes. Next time I see her I am going to get on Armour."

2 / 10
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  • jrb
  • Taken for less than 1 month
  • February 7, 2020

"I had a partial thyroidectomy in 2007. I've been on generic Levo 88mcg for about 10 years now. Maybe it would be different had I been started on Synthroid from the get go but I've tried Synthroid two times, once at 75mcg and this week at 88mcg and the results were the same. Within three days I had muscle weakness, muscle spasms, more pain in neck and extreme fatigue. Regulation mandates 95-105 % of the active ingredient be present. I've taken Unithroid 88mcg and I never had the extreme symptoms like with Synthroid. I steer clear of this med because I can't afford to miss another week of pay fiddling around with it. Generic and Unithroid aren't perfect but at least I can function."

1 / 10
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  • Mizz...
  • October 27, 2014

"Had partial thyroid removal with benign tumor 30+ years ago, was OK until about 2 years ago and routine bloodwork showed low thyroid. After 2 years being OK on the medication suddenly the thyroid levels are dropping again, hair falling out, skin is breaking out in itchy red welts, gaining weight, so Dr upped the dosage. A couple weeks on higher dose I feel like I am "wired" in high gear, can't sit still, talking to myself going in circles, and my hot flashes have really really ramped up big time. Dr. says to give it at least 60 preferably 90 days to adjust, not sure I can hold out that long before stopping it. Hoping there is a better solution out there someplace."

7 / 10
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  • CMIRE
  • March 6, 2012

"I've been taking synthroid for about 3 years. I had to have radiation on my thyroids because they couldn't control levels. It just would go real low than extremely high. I'm on a 300 mg taking mon through to sat. I'm feeling better but it takes a long time before they find the right dosage."

9 / 10
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  • Marbunk
  • June 17, 2021

"I have taken Synthroid (branded) since 2005 (dose .075) with no issues or side effects, have kept annual notes on TSH t3 t4 test results since that date. Recently, my TSH dropped to .25 with t3 and t4 in normal range. Doc switched me to .50 from .075 because my TSH was low. The side effects were absolutely awful for 5 weeks with the worst being muscular pain throughout my whole body afraid my legs would give out. I stopped taking after 5 weeks for 2 days while waiting to see Doc to see whats happening. Within 1.5 days, the symptoms relieved without any pain medication. I believe there is some change to the drug and have contacted Abbvie (waiting for an answer) to see if the fillers (which are numerous) have been changed from 1 dosage to another. If you are having any side effects, you must call them and report it, especially if they are long term or severe as mine were. I am back on .075 with no issues...... something is wrong here. Will keep posted."

1 / 10
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  • ThisG...
  • Taken for less than 1 month
  • April 25, 2017

"After seeing my ob for some problems with menstruation, I was sent for about 10 different blood test to check my hormone levels. Let's just say that we found the source of my problem and I was referred to an endocrinologist. She wanted to repeat my TSH level cause she said that being at 3.65 was a little high for someone my age. So I went back within 4 weeks to get retested and my TSH was 10.36 and I was feeling it. I was so tired I could barely get out of bed. My headaches were out of control and I gained about 10 lbs in a months time. I just started 75mg Synthroid a few days ago so I'm feeling optimistic. I feel once we get my pituitary adenoma, thyroid and my vitamin D under control I'll be so much better. ADVICE: listen to your body."

6 / 10
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  • Ayapl...
  • December 6, 2017

"I used Synthroid (25, 50 or 75 for over more than 10 years, but had to use the original, not the generic because generic does not work in some people. I've not been operated, but for over 2 years I've been using NatureThroid (32.5) instead which was recommended by my ND and have to say that all my side effects that Synthroid caused, had gone. I almost lost all my hair and had terrible heart beats, headaches, joint pains, etc. I do not have hashimoto, and really don't know if it works for people with this condition, but I tried NatureThroid and I am very happy with the results."

1 / 10
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  • Anonymous
  • October 4, 2009

"I've been taking Synthroid for a few years and has really helped. My dose has gone up several times. I can really tell a change in how I feel now, then before I was taking it. Tried the generic and it actually made me feel worse so I am taking the name brand only."

9 / 10
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70 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.