Fetzima and Vomiting: What Users Say

• Non...
• Taken for less than 1 month
• January 23, 2019

For Depression "Prozac quit after 10 wonderful years. Tried many others. Nothing. Then Fetzima can’t get by 20 mg tablet due to nausea, bloating. Then attack either gallbladder or something else? Severe vomiting. Did Fetzima trigger gastrointestinal problems? Hasn’t improved mood either. Going off. What to try next? This is a crazy circle. Hopefully, one day there will be something better than “try this,” “try that” approach. At 70, ready to give up."

• asd...
• June 4, 2014

For Depression "The potential side effect list became my life. I got everything, the extreme sweating, nausea, dry mouth, constipation... all of it. Had to stop going to my daily kickboxing classes completely because I'd get dizzy and throw up every five minutes until I stopped working out. I had to plan taking it around being able to spend two hours in bed not moving in air conditioning just to keep it down. Saw 0 effect on mood. I was switched to a new one yesterday, and hopefully life gets better."

• ksm...
• June 19, 2014

For Depression "I was only able to take it 4 days. On day four, I got very ill. Started as uncontrollable depression, then violent vomiting. I proceeded with Dr. advice to go back to old medicines. I've been off it 2 days. I can't eat without severe stomach pain, no matter what I eat."

• Tir...
• January 14, 2016

For Major Depressive Disorder "I have adult ADD, anxiety, and chronic pain. Had to switch docs (he moved), and the new one insisted I try Fetzima. I have been on it for a week. In addition to severe nausea and vomiting, my stomach is rigid. I have been having bursts of rage that have started to become directed inward. Thoughts of self-harm (though not ones I would act upon). Have had flashes of suicidal ideas and am sad. I wasn't sad at all before I took this drug-just anxious and couldn't focus. I have had serious problems with all antidepressants I have tried in the past. I'm reacting in a similar way, though it is less severe, and my anxiety (when I'm not angry) is marginally improved. Not enough benefit to outweigh thoughts of self-harm and suicide!"

• Tif...
• May 18, 2017

For Major Depressive Disorder "I've tried damn near every med you can think of. I have MDD, GAD, PTSD, ADHD. Wellbutrin stopped working after 3 years, and I don't do well on SSRIs (Fetzima is SNRI). So I said, everyone is built different, so trial and error/guinea pig it is. 20 mg once daily for 2 days, then up to 40 mg/day. Day 1 had completely 0 side effects. Day 2 nausea and vomiting lasted until day 5, which is when constipation began. BUT my depression is under control despite environmental factors I can't control. I am less emotional, moody, or irritable in general. Suicidal thoughts don't last as long as before. I'm not a zombie. No weight gain. It's good. Not great. 7/10 for me. Started 80 mg today, nauseous but will subside. I'm pretty stable. Give it a chance."

• Jam...
• Taken for less than 1 month
• February 14, 2016

For Major Depressive Disorder "I've tried Zoloft, Prozac, Effexor, Viibryd, and now this. Started with 20s for two days before going to 40s. First three days, I was vomiting, nauseous, and itchy. When that subsided, the depression got way worse (which is huge considering how bad it was before). I cry and sleep way more. I feel suicidal and reckless. Calling my doc first thing Monday morning to change plans because this is not working."

• Anx...
• Taken for 1 to 6 months
• August 13, 2019

For Depression "Fetzima is ruining my life. It's like poison. After being on Paxil for 4 years, I weaned off it with my doctor's direction. After withdrawal was so awful, my doctor put me on Fetzima. The first 2 weeks I experienced all-day gut rot. The doctor said that wasn't Fetzima causing it. Weeks 3 and 4 were pure torture. From vomiting daily, diarrhea, crying nonstop, fits of rage, chest heaviness, lost 12 lbs. Can't eat, feel like I'm losing my mind. After 30 days, I stopped these meds cold turkey. I'd rather suffer with GAD than live on these kinds of meds. Never been so sick. Haven't been able to work. In my opinion, Fetzima is garbage."

• Wom...
• Taken for less than 1 month
• October 23, 2018

For Depression "Trying this for depression, nothing major, lost my motivation and enjoyment for the usual things. Horrible vomiting a few hours after the first 20 mg. Pharmacy says try Gravol with it. Tried it for 12 days, had chills; my extremities are frozen, feet, nose, and hands like blocks of ice. Nausea is debilitating; I felt exhausted 24/7. So I stopped for 5 days to allow the nausea to go away. Tried again after 5 days of break. Day one okay, days 2, 3, 4, and 5 the nausea is back and overwhelming. As soon as I try to get mobile, the nausea sets in. Sleep is non-existent. I don’t think this drug is for me. Back to the doctor I go."

• bor...
• Taken for less than 1 month
• October 24, 2016

For Major Depressive Disorder "I gave it a 5 because I'm only on day 5 of treatment. The only reason I'm leaving a review is because the side effects have been awful already. I've vomited every single day between last Wednesday (first dose) and today (Monday, 5th dose). I've had a killer headache 3 out of 5 days. I can't sleep for longer than a couple of hours, which makes no sense as I'm on 2 different sedatives - I should definitely be sleeping. And I've been constantly covered in sweat. Even when I feel cold, I'm sweating like an animal. I haven't noticed any mood changes (positive or negative), which is expected because of the short time I've been taking it. I just thought I'd share the side effects and hope they go away with continued treatment!"

• sum...
• Taken for 1 to 6 months
• April 10, 2019

For Depression "Be careful before deciding to take Fetzima for depression, it is absolutely horrible. Caused me severe vomiting almost every day. The worst part was the way it messed with my brain chemistry, making me angry, confused, and having severe mood swings. It’s been almost 2 years since I’ve been off this medication and still look back on this medication as a real nightmare. It REALLY makes things worse. DON'T TAKE IT."

• Ver...
• April 20, 2018

For Major Depressive Disorder "I'm on lamotrigine, and as unsure as it could be, my own reaction. I suffered horrible symptoms for 3 weeks - migraines that lasted for literally 2 weeks straight - eye pain (I do have glaucoma) - upset stomach - once vomited - after coming off, severe violent mood swings leading to outbursts - neck pain, back pain, which on week 4 has not gone away yet - muscle pain - muscle flinching as if my brain was giving shock through my body - severe confusion to the point I couldn't tell what happened and didn't really happen - weakness to the point I could hardly get up - severe chest pain - always out of breath - sore nose as if stinging - blurry eyes - watery and burning eyes - broken sleep - thoughts of losing sanity - weight gain - out of control hunger - chills - sweats - shaking - shivering - difficulty warming up. This was only 2 weeks, by week 4, I'm only now starting to feel better."

• Nit...
• Taken for 2 to 5 years
• August 2, 2022

For Major Depressive Disorder "The worst drug I have ever taken, and I have taken at least 50. Caused extreme anger/rage outbursts over simple things. It jacked my heart up 45 beats, I was having serious AFib. Not to mention, after four years, I have never experienced a drug this physically addicting. More physical and intense withdrawals than coming off Benzos, by far intense stomach pain, nausea, vomiting, migraine, dizzy, just feel horrible, and this is a taper. This medicine turned me into a very scary human being, and discontinuing it is just as scary. Don't take this medicine, if you do, be prepared to deal with insane rage."