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Letrozole User Reviews & Ratings (Page 3)

Brand names: Femara

Letrozole has an average rating of 6.5 out of 10 from a total of 355 reviews on Drugs.com. 49% of reviewers reported a positive experience, while 23% reported a negative experience.

Reviews for Letrozole

  • Ash
  • January 10, 2021

For Female Infertility "I was diagnosed with unexplained infertility. I took Femara one month shy of a year, started at 2.5 then upped to 5mg. After almost a year, I went to a new doctor. We set up a plan and just let my last cycle of medication run its course from the other doctor. My next month appointment, she was in delivery with other patients and I had to reschedule. I was desperate and just started googling everything. My husband and I were having sex multiple times a day, but I had read online that if you have sex during the next couple days after ovulation, the egg won’t implant. The percentages were high, so after ovulation, we waited three days. A week later, I was pregnant. It was literally the only thing we did differently. Two years of trying non-stop, we finally did it. I honestly think waiting after ovulation is what did it for us. I never heard this before."

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  • Baby...
  • Taken for 1 to 6 months
  • March 10, 2024

For Female Infertility "I've been trying to get pregnant for 15 years. I only have one son who is 16. I wanted to have two children back to back and be done, but it didn't happen. My doctor prescribed me Letrozole 2.5 for cycle days 3-7. I got a faint positive test one day before my missed period. I'm 5 weeks pregnant."

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  • Erica...
  • February 9, 2013

Femara (letrozole) for Breast Cancer "I have been on Femara for almost a year. At first, I had nearly constant hot flashes and night sweats. I was started on Effexor with nearly immediate relief. I have had increasingly painful joint and muscle pain, especially in my knees. Nothing seems to be helping much with that, and it has been a major detriment to my quality of life. I have recently added Magnesium, Fish Oil, and Glucosamine/Chondroitin to the Calcium and D3 I had been taking. Hopefully, this will ease the joint stiffness and pain. I am 52, and some days I feel 92. Still, I am cancer-free so far, so I will continue to take Femara."

7 / 10
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Frequently asked questions

  • inday
  • Taken for less than 1 month
  • June 23, 2020

Femara (letrozole) for Female Infertility "I recently found out I have PCOS. My periods were regular, never late. Then I went to my Dr. She gave me Femara. I just took my first pill 2-5 days of my period, and I'm still hoping this month or year to get pregnant. Keep on praying."

5 / 10
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  • Stage...
  • Taken for 6 months to 1 year
  • January 9, 2020

For Breast Cancer "Started on Anastrozole for 4 months. It was debilitating to me. Could hardly move, could not sleep, could not focus, had serious brain fog. Oncologist switched me to Letrozole. Started off good, then about 4 months into it, I noticed my hands and feet were so sore, could hardly move them. Swelling, weight gain, intense hand, knee, and foot pain, foggy brain, sweating all the time. The knee pain got so bad, I could hardly walk. Took myself off them, seeing the oncologist in a couple of months. She said I had to have a bone scan and possible transfusion because Letrozole was known to cause issues with bones. I am 54 years old and was feeling like I was 80. I want a quality of life, decided to take the risk at this point. They all have the same side effects, not worth it to me."

1 / 10
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Are you taking this medicine?

  • Lexie
  • Taken for 1 to 6 months
  • March 3, 2020

For Female Infertility "I have been taking letrozole for 7 months now and I finally ovulated in January!!! So I’m hoping to get pregnant this month!! This treatment really works, just have to be patient, ladies. I hope we all have a safe pregnancy and birth."

10 / 10
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  • Red
  • Taken for 6 months to 1 year
  • November 11, 2019

For Female Infertility "I struggled for many years to try to conceive. About 5 years ago, I started taking letrozole 2.5mg once a day. I wasn't producing follicles so after 2 months, they upped my dose to 2.5mg twice a day, and this was working. But they wanted to give me an extra boost to make me ovulate, so they prescribed me an HCG shot to take to ovulate. I now have a healthy 4-year-old and a healthy 2-year-old. It took me 5 months to get pregnant with my 4-year-old and 7 months to get pregnant with my 2-year-old. Now crossing my fingers because I have been on letrozole with HCG shot for going on the 7th month. Good luck to you all."

10 / 10
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More FAQ

  • Almost...
  • Taken for 1 to 2 years
  • January 6, 2020

For Breast Cancer "I was on Letrozole for one year. Stage 1 breast cancer, no lymph node involvement. ER/PR+ HER2- Why I was put on this drug is beyond me. I now need hip replacement. I have stress fractures in my shin. Every joint in my body aches. I stopped taking the drug after one year. When I see my oncologist, I will tell him I stopped taking it. Although I stopped the drug in November, I am still having bone pain and joint pain. I use a walker because of my hip and stress fractures. I did not have any problems before taking this medication. I hope the FDA changes its use for breast cancer patients."

1 / 10
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  • Treas...
  • October 25, 2020

For Female Infertility "Have been trying to conceive for some months now, started letrozole 5mg on days 3-7. It's my first time and I'm very hopeful it works for me because I am so encouraged right now by some comments here. Baby dust to everyone."

10 / 10
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  • Jan
  • May 15, 2016

For Breast Cancer "After taking Letrozole for about 6 months, I had the aching muscles, etc., felt like a 90-year-old! Then I did a lot of research! Take your calcium and MAGNESIUM (which is a muscle relaxant); it is amazing, no more aching bones! I take 2 magnesium a day, one in the morning and one an hour before I go to bed. Don't take it at the same time as your calcium; wait a couple of hours! Read up about this brilliant supplement! It also gives you energy, etc. I seriously thought about stopping taking Letrozole, but along with the Adcal and Magnesium, I feel great! Also, I get these on prescription!"

8 / 10
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  • Anonymous
  • Taken for less than 1 month
  • March 2, 2023

For Female Infertility "I had been trying to conceive for 18 months with two miscarriages and no luck for a sticky pregnancy. I took one round of letrozole 2.5mg cycle days 3-7 with progesterone suppositories after a confirmed ovulation lab. I got pregnant and tested positive on 8 dpo! Currenly 7 weeks and about to head in for my first ultrasound. Letrozole works! I am amazed."

10 / 10
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  • Tina...
  • Taken for 1 to 6 months
  • March 20, 2024

For Female Infertility "It took me 5 years to have my daughter who is now 14. When my daughter turned one, I found out that I had a miscarriage, which made me want to try for another baby. After 12 years and 5 miscarriages later, I was really concerned that I wouldn't have any more children. I was very blessed to get my daughter! I tried 4 other treatments from different doctors, but when I went to a new OBGYN that gave me letrozole 2.5mg, I thought it would just be another fail. With a lot of prayers going up, God answered and said this prescription is the one that will work for your body. He blessed me with a healthy baby boy. He's now 14 months old, and we didn't have any issues at all. Everything went according to plan. We're actually going back to the OBGYN to try again so he'll have a sibling to grow up with! Oh yeah, I don't want to forget to mention that it actually worked with the first prescription we took, the first month of it!"

10 / 10
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  • cauryn
  • August 30, 2013

Femara (letrozole) for Breast Cancer, Adjuvant "I had stage 3 breast cancer, have been through chemo, radiation, and have been on Femara for 4 months. I started on Aromasin but had terrible joint and muscle pain, so my oncologist changed me to Femara. My joints and muscles feel better, but I am so tired that even my oncologist tells me I look worn out. I will live with the fatigue as I know this medicine works. I am 58, and I can no longer do what I did less than a year ago. I ride a bike 40 minutes a day, I eat healthy, but I just have no vitality. I miss my old self."

4 / 10
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  • Anam
  • Taken for less than 1 month
  • August 28, 2020

For Female Infertility "I have PCOS, I have taken Clomid for 3 months to try and get pregnant but it didn't work. Now my doc gave me letrozole 2.5mg. But after my last day of period I am still having vaginal bleeding. Is that normal?"

6 / 10
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  • Anonymous
  • March 5, 2022

For Female Infertility "I’ve been trying to conceive from 2017 to 2022. I was seeing an endocrinologist and all he suggested was IVF. Finely I saw a new endocrinologist January 2022 and he was great. This doctor suggested I take Letrozole 2.5mg twice daily to ovulate because I have PCOS. He also suggested I get the digital ovulation clear blue test so I can test for ovulation. I did exactly what the endocrinologist doctor told me to do and got a positive ovulation test February 8th and 9th. Positive pregnancy test February 22nd and a beta hcg blood to confirm pregnancy levels of 1449. I’m currently 5 weeks and 2 days pregnant early I know but letrozole worked for me. I have had problems getting pregnant for 5 years, one hsg, almost did an IUI and now I’m pregnant. I’m so excited letrozole worked on day 3 of cycle to day 7. I had no side effects in taking Letrozole."

9 / 10
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  • Ezel
  • Taken for 1 to 6 months
  • June 9, 2022

For Female Infertility "If you are wondering if this medication will work then there’s me, a living proof that letrozole works! I've taken it orally from day 3-7 cycle then had timed sexy time with my husband. Baby dust to all women! May we all conceive in Jesus’ Name."

10 / 10
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  • Abc
  • October 25, 2020

For Female Infertility "I have taken letrezole 2.5 mg from day 2 to day 6 in Aug2020 but I got my periods. Then my doc recommended me clomid 50mg next month but I didn't take it as my flow was very light. Now my doc again recommended me letrozole 2.5 mg ...so hoping for postive test next month. Wish me luck and pls pray for me ...may everyone get baby soon"

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  • Anonymous
  • July 7, 2014

For Breast Cancer "I have been on Letrozole for 9 months. I have dry mouth, extremely dry skin, vaginal dryness, reduced libido, weight gain, and hair loss. My joints are increasingly stiff and painful. I wake in the night from pain and can scarcely walk first thing in the morning. My breast cancer was stage one and I had both breasts removed. I am considering stopping taking it."

4 / 10
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  • tinyb...
  • Taken for 6 months to 1 year
  • April 29, 2023

Femara (letrozole) for Breast Cancer "Awful! I've been on Femara for about 8 months. And since I started, I seem to have every single side effect. My joint and muscle pain is excruciating. In no particular order, I suffer with body pain (fingers, hands, shoulders, chest, back, sides, hips, legs, feet - basically everything head to toe). Plus, weight loss, hot flashes, headaches, dizziness, thinning of hair, dry mouth, high BP, night sweats. Even my scalp is tender. Chest pain that radiates to upper arms, shortage of breath, over all depression. Chills, insomnia, intestinal pain - sharp pains, plus dull aching. Constant feelings of nausea, diarrhea, constipation. I'm afraid to eat but also have little appetite. Brain fog, shortness of breath. Feeling that I am just going to die. Sitting up in pain all night. I hurt everywhere - too sick to move; too sick to cry. Feels like I am going to have a heart attack. Can’t lie down, can’t stand up. Full body chills, hands shaking. Haven't slept through the night in months."

1 / 10
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  • Shorty
  • September 21, 2016

Femara (letrozole) for Breast Cancer "I've been taking letrozole (Femara) for 9 months, after a right-side mastectomy for stage IIA breast cancer. I'm ER & PR positive. No radiation or chemo. I'm 58 & this is the only drug I take, besides vitamins. The first 6 weeks I had trouble sleeping, occasional dizziness, some joint pain, & mild headaches. Around 4 months in, I started losing hair. I'd guess approximately 25% of my hair has fallen out. Besides the hair loss, I have dry eyes, genitals, & skin. There's some stiffness & joint pain in my hips. These side effects are tolerable, especially knowing that the drug is preventing a cancer recurrence. None of these side effects are enough for me to stop taking letrozole!"

8 / 10
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  • Miledha
  • Taken for 1 to 6 months
  • April 27, 2016

For Breast Cancer "After 4 months on Letrozole, I felt like an old crock, in pain everywhere, barely able to move, depressed, not sleeping well and developing carpal tunnel syndrome. I've gone off it ready to try something else and after only a week, nearly all the pain and stiffness is gone. I'm sleeping well and have a sense of well-being. Letrozole stole my quality of life and I'm glad I discovered it after not too long. Let's hope other drugs are better tolerated, but if not, I'd rather have quality of life than quantity of pain."

4 / 10
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  • Anonymous
  • July 14, 2009

Femara (letrozole) for Breast Cancer, Metastatic "I have been using Femara for 8 months, and I have been having very few side effects. I get the hot flashes only once in a while now. I do have some joint pain, but that has been easy to tolerate. If that means I will have a longer life, only God knows that. There is always hope, just keep the faith and have no doubt in the medicine, doctors and mostly God."

9 / 10
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  • Clp
  • Taken for 6 months to 1 year
  • January 16, 2021

For Female Infertility "My story: I did not have any periods for a year and after tests was diagnosed with PCOS. I was referred to a fertility clinic as have been trying to conceive for over a year. They started me on 2.5mg letrozole to kickstart ovulation but I didn’t ovulate in the first month, so the dose was doubled to 5mg (two tablets) and I began to ovulate which was good news. However unfortunately after 6 months of taking double letrozole I have not had a pregnancy. I’m now being re referred for IUI/IVF. Everyone is different, and it’s nice to see the success stories here. Many ladies seem to have achieved pregnancy with letrozole which is lovely, it gives us hope. Stay strong and keep going x"

5 / 10
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  • ramade
  • June 5, 2013

Femara (letrozole) for Breast Cancer, Metastatic "Femara for 18 months, no side effects for first 6 months, then joint and muscle pain, physical fatigue, bone density loss. Will continue for as long as it works, at the moment looking clear, I want to live."

10 / 10
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  • Lizzie
  • Taken for 2 to 5 years
  • February 2, 2021

For Female Infertility "I hope you all get pregnant but this is a drug review site , That being said here is my review. PCOS and conceived on first round letrozole in December 2019. Miscarried in Jan. Conceived again on 2nd round in July 2020 , miscarried in Sept. Currently on my next round. 5mg day 3-7 and side effects are ... tired , dizzy, blurred vision, depressed and anxious. It’s only 5 days ladies. It’s worth it. It works. Hang in there."

10 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.