Ixekizumab for Plaque Psoriasis User Reviews

• Sid...
• January 4, 2019

"The benefits of Taltz for me are fantastic. I've had plaque psoriasis since I was 16. I’m 54 and have been clear for 2 years. It also helps with my osteoarthritis pain. I know the injections can hurt. I allow the injector to reach room temperature. Then I ice the injection site. It's hit or miss on pain. But if being slapped across the face once a month cleared my psoriasis, I’d do that too. Just saying..."

• DWO...
• Taken for 1 to 6 months
• June 7, 2016

"This drug is what my doc put me on when I asked for Cosentyx. She said it had a little bit better success rate and might be a little cheaper. She also told me that I would only have to do labs once per year. I have moderate plaque psoriasis from head to toe. I should say HAD. I am 99% clear at 4 weeks. I only have light spots where plaques used to be. The only other biologics I have had are Humira, which worked for a year or so, and Otezla, which did not work at all. The only side effects I have had have been a slight touch of digestive trouble and maybe one day of mild (flu-like) body aches. My cost after insurance and copay assistance is 5 bucks per month. Needless to say I am super happy so far. So far, so great."

• Hgr...
• Taken for 1 to 2 years
• September 8, 2018

"I’ve been using Taltz for a year now. I’ve suffered with psoriasis and psoriatic arthritis for about 20 years. I’ve tried everything, and nothing seemed to work completely. Some meds worked okay on the plaques but didn’t touch the joint pain! When I started using Taltz, I noticed a difference in my skin in about 4 weeks. After 3 months, I was completely clear! I said completely clear! After having plaques for decades, you can imagine how ecstatic that made me. My joint pain has improved so much that I’m able to take dance lessons! Yes, the injection is the most painful medication I have ever taken, but the benefits are totally worth it. I can play with my kids and dance with my husband! I can wear a bathing suit on vacation or wear a skirt or short sleeves to the office! I wish the shot itself weren’t so painful, but for the first time in my life, I’m not a prisoner to my psoriasis and joint pain!"

• Lef...
• Taken for 6 months to 1 year
• April 11, 2020

"This has been a wonder drug. I tried Otezla and Humira, and neither got rid of my plaques. After being on Taltz for about 2 months, all of my plaques are completely gone. Zero side effects. I now have been on Taltz for a year, and my plaques have not returned. This is the best I have ever felt since first being diagnosed with psoriasis as a kid."

• Sco...
• September 9, 2016

"This stuff is absolutely amazing. I've been on Enbrel, Stelara, Humira, methotrexate, topicals, and none of them have ever done this well. Within 3 days of the first injection, I started to see clearing. I thought, no way! But it has only continued to get better. I'm about to inject my week 5 dose and most of my areas are scale-free. My self-esteem has gone way up. My wife isn't complaining about flakes in the bed. No bloody spots on the sheets from picking. I can wear dark-colored shirts, short sleeves, no sleeves again; and not be concerned about people staring. Yes, the injection stings. Yes, sometimes the injection leaves a swelling under the skin. But for me, it is completely worth it."

• Dea...
• Taken for 6 months to 1 year
• May 2, 2019

"After dealing with psoriasis for over 50 years, I am finally totally clear. I started Taltz 9 months ago with concerns about taking a biologic. So far, I have had no side effects, and I am looking forward to wearing summer clothes without embarrassment. The shots do hurt, but it's well worth the results. It helps to swear while injecting. I qualify for a $25 co-pay per month. If not for that, I would never be able to afford it. It's a lifesaver for me."

• Tal...
• November 10, 2016

"I have been on this study for nearly 3 years. My psoriasis has been a problem since I was young and have dealt with it for 30 years! I have tried all sorts of different drugs over that time, and nothing has given even close to the same results as this. It truly is a miracle. I take one shot a month, and I'm clean and clear of everything! Just like others have posted, it took about 2 weeks to show big improvements, and by a month in, you wouldn't ever guess I suffer from severe plaque psoriasis. I thank all the doctors and nurses that have helped me through this process, and I'm very happy to see this hit the market! Hope it works as good for you as it has for me."

• Rob...
• Taken for 1 to 6 months
• November 14, 2019

"Was on the Otezla pill for about 4 months, it began to work for my psoriasis, on lower shins and elbows, but then stopped. My skin doctor recommended Taltz. Took this, and I did get very clear on this, but began also noticing terrible, yes terrible, side effects as it really affected my immune system. I got so many fungal-related infections - ringworm, I got athlete's foot, my stomach was killing me, and I developed fungal infections all over my body. Still fighting a serious fungal infection in my sinuses, and now today had X-rays of my lungs, thinking I must have pneumonia. Now may also have a serious fungal infection in my lungs. I am so mad at Lilly for putting out such garbage, as Taltz makes people very sick. I understand that 27% of all people get very sick on Taltz. I have not noticed in a while now any more commercials on TV about Taltz. Did they take this off the market? I am still very ill, even being off of this drug for 4 months. But it lowered my immune system and got me very sick, I plan on suing."

• Hom...
• Taken for 6 months to 1 year
• June 27, 2020

"This drug worked pretty well while I was using it, and the company has very friendly and cooperative service representatives. Be that as it may, you need to understand that this is a lifetime investment if you start using it. If you have to stop using it for any reason at all, like I did, please don't start. My psoriasis came back much worse, and the areas of my body affected increased 5x. I don't know why this is, but it is important that prospective users are aware of this hidden side effect."

• Tal...
• August 25, 2018

"35 y/o female, issues with mild psoriasis for decades and in April became severe after having strep. I was covered. My scalp was covered, and spots started to appear on my forehead and face. My back was completely covered, and my arms and legs looked like a horrible case of chickenpox. Started with a steroid shot that seemed it was going to work, a week later it came back with a vengeance! Then tried other injections (also immunosuppressors), same thing, acted like they were working, but a week in it was back full force. I began Taltz with 2 injections, then 1 every 2 weeks for 6 doses, then 1 a month. I am beginning the 1 a month regimen now. I was completely clear in days. I haven’t been sick and work in a high-risk profession of catching colds/flu/etc. The injections are painful but quick. First, the injections left large welts, but that has subsided. I would take that any day over the psoriasis. I recommend taking the medication out of the fridge a couple hours before injection and follow it with an ice pack."

• Sco...
• April 24, 2019

"I have suffered with plaque psoriasis for over 40 years. I have tried several treatments over the years. I tried Methotrexate, this was a miracle drug, but everything runs its course I guess. I’ve tried other biological drugs, which haven’t worked. Then my dermatologist suggested I try Taltz. I was a little nervous, but by now the pain from my plaque psoriasis was so sore. Anyway, I took my first double dose of Taltz 2 weeks ago. I injected into my stomach, either side of my belly button, and yes, it does sting, but it wasn’t unbearable. Within days, I started to see a difference, my legs were looking less red and painful, and less itchy. It felt amazing seeing such a difference so soon. I look 60% better already, I can’t believe it. I’m about to take my next injection, and I’m hoping the progress continues. I can’t wait. No side effects up to now, I feel great, trying to stay positive. This medication looks like we’re going in the right direction to find a cure."

• Sus...
• Taken for 1 to 2 years
• September 14, 2018

"I’m 61 and have had psoriasis since I was 8 years old, have tried every treatment. Tried Otezla, and it affected my liver, kidneys, so got off that. I started Taltz a year and a half ago with fabulous results. In the last 8 weeks, I have never, ever been so sick with a sore throat, swollen lymph node on the right side, cough, and sticky phlegm. I feel lousy on and off, and this throat infection won’t go away. I have had every blood test, strep test, and everything checks out fine. I’m on hold now for the next shot. Wondering if anyone else has had this problem and what I should do. I have to go back to work, but if I’m this sick all the time... is it worth it? Any other comments would be appreciated."

• Rac...
• Taken for 1 to 6 months
• February 16, 2019

"I have been on several biologics over the past few years for psoriasis and psoriatic arthritis. This is the only one that has worked. I work in sales, and the disease process had severely affected both my professional and personal life. My former boyfriend broke up with me due to the skin lesions associated with this disease process. My immune system is a bit weaker, but my quality of life has drastically improved. I am beyond thankful."

• Mea...
• July 18, 2016

"Injection burns like fire!! But the results are incredible. After 3 treatments, almost all areas are cleared. Legs were raw and would bleed daily over most of the lower leg. Now only slight redness still exists. This has been a miracle drug so far. Had previously used Stelara and Otezla, without much result."

• Cat...
• Taken for 1 to 6 months
• September 28, 2018

"43 yr old female, psoriasis since 9 yrs old. Tried Humira 50% cleared, Stelara 90% cleared. Tried others because Dr. thought I could be 100% clear - Cosentyx maybe 60% clear now Taltz. Skin looking OK, like it might get to 90% during loading stage (12 weeks) BUT injection site pain and reaction over my whole thigh, can’t wear pants, but it did get better by icing immediately after. Other side effects - heavy scaling in my hair, ear infections fortnightly, thrush, skin rash/chafing, dry nasal passages, my nostril has split and scarred on one side. Thick sticky discharge from my nose, ears, and eyes and developed a rash reaction to the discharge at the corners of my eyes, nose, mouth, and my ears including my earlobes. Hearing issues and can’t see when eyes inflamed. I am really sick, 1 month since stopping it and waiting and praying for side effects to improve. ENT specialist booked for 6 weeks' time, absolutely not worth it for me unfortunately."

• Han...
• August 15, 2018

"I have been on Taltz for about 8 months now, and before Taltz, NOTHING even subsided my psoriasis. I am now completely clear of the plaques (still have the white spots that occur when the plaques go away). The only downside to this medicine is it really does weaken your immune system. I was never sick before this medicine, and now I am ALWAYS sick. Strep throat, multiple infections, colds, everything. I've gotten so sick I've almost considered this medicine not worth it even though it's effective. What's even worse is that I'm on a trial for the child version of the medicine. Overall, really effective medicine, completely clear, yet always really sick."

• Lin...
• Taken for 1 to 6 months
• May 26, 2019

"I have tried everything for 24 years, and only Taltz has worked. My psoriasis has gone completely!!! I was covered with it. I feel so much better. Thank you for giving my quality of life back. God bless you."

• Tab...
• Taken for less than 1 month
• June 22, 2018

"I have had psoriasis on 75% of my body for about 15 years (since I was 9). I have been to many doctors, used creams, phototherapy, Enbrel, and Humira. I have been on Taltz for 12 weeks now and have completely clear skin. It is amazing to feel like a person again and not be in constant, dry, flaky pain. The injection hurt more than any I have ever had, and the injection spots were horrible. I learned a lot of tricks to mask that pain, and the spots have not been as bad since. I love Taltz, this medication has changed my life."

• tal...
• Taken for 1 to 2 years
• September 9, 2018

"It's been over a year on Taltz, and I am 100% clear. Miracle drug for me and improved my quality of life. Was in Hawaii last week and sunbathing, snorkeling, swimming like any other person without feeling ashamed. One last callout: I see a lot of negative reviews on Taltz due to the injection. I migrated from autoinjector (very painful) early on to a normal needle, and the latter has minimal pain."

• Mat...
• Taken for less than 1 month
• October 12, 2016

"I took my first dose a week ago. Within days, I started to see improvement. I have psoriasis all over. Some smaller spots, some larger than a softball. Now, at a week, my thickest plaques are almost gone. I still have discoloration at the sites, but no plaques. I've been on Raptiva, which worked very well until they took it off the market. I've been on Humira, Stelara, just about all the topicals you could name, and most recently Enbrel for the last few years. I really can't believe how quickly this cleared my skin. The only thing that gave me this type of result was cyclosporine, and that took over a month to get this clear. I'll admit that the auto-inject was not the most pleasant feeling, and I typically use a prefilled syringe."

• Anonymous
• August 24, 2018

"I just started Taltz. My first two injections were two days ago. I’ve done auto-injectors before, but this one is so painful that I have to have someone else do it for me. Is it the injector itself or is it the medication? Am I doing the injections wrong? Idk."

• Cen...
• Taken for 1 to 6 months
• July 28, 2018

"39-year-old male who never had previous issues until about a year ago. I developed psoriatic arthritis and plaque psoriasis that covered 80-90% of my body. I tried multiple other medicines without any success. I was finally able to see a new rheumatologist who gave me my first 2 shots of 80 mg TALTZ, and I was on my way to clearer skin and less joint pain. Now, almost 3 months later, I'm almost completely clear of plaque psoriasis except for a few scars along my lower legs. I can honestly say this medicine has saved my life and given me the quality of life back that I had prior to this psoriatic arthritis and plaque psoriasis breakout. I know it's something I will forever have to deal with, but I'm thankful my doctor found a medicine that works for me."

• Sco...
• Taken for 1 to 6 months
• July 20, 2019

"Just wanted to give an update. I have now finished taking Taltz every two weeks, and will be injecting every four weeks. I had very severe plaque psoriasis, thick, which basically covered all my legs. Although I’ve had amazing results, I’m about 80% clearer since starting this drug. I still have lots of smaller patches on my legs. I’m just hoping in time these patches will also disappear and not start to get any worse. Now I’m moving to injecting every four weeks, keeping my fingers crossed. I feel good, no infections, amazing drug."

• ATL...
• July 11, 2016

"Taltz caused severe swelling the size of hockey pucks that lasted an entire week at injection sites for the initial two injections (mid-thigh). Thought it was just my body adjusting to the new medication, but upon week #2 injection, an even worse reaction! Same 'hockey puck' under my skin as week #1 and spread to an 8' hardened 'pancake' under the skin with redness, severe swelling, itching (for a week and counting). It is painful and radiating heat, an under-the-skin 'hive.' My doctor believes I may be reacting to a certain protein often used in injections. I was on Stelara = no improvement, tried Humira, and had some improvement but problems getting the product shipped at proper refrigerated temps and flimsy injections needing to be replaced."

• Twi...
• Taken for 1 to 2 years
• July 19, 2018

"I actually have guttate psoriasis. I tried light therapy, creams, and Otezla. Taltz is amazing! I have cleared up pretty much 95%! Using this drug, there is a good 5/10 second pinching feeling when using the auto-injector. I found I'd really swell up around the injection site for a few days. But I started taking allergy pills/antihistamine a day before my shot and a day after, and it really helped the swelling. Being on any drugs sucks, but this really did a miracle on my psoriasis."