Leqvio and Pain: What Users Say

• Man...
• Taken for 1 to 6 months
• January 20, 2025

For High Cholesterol "I took Leqvio because of my high cholesterol. My main health concern besides cholesterol is that I have peripheral neuropathy. I noticed recently that my calves are extremely stiff, and I have pain in my calves. For those reasons, I am considering stopping Leqvio. I will make a decision shortly."

• 194...
• Taken for 1 to 6 months
• August 31, 2024

For High Cholesterol "I have been on this injection for one month, absolutely in agony, painful legs, feet, toes, shoulders, knees, burning skin. Contacted the cardiologist, and his reply was, 'I’ll put you on steroids.' No thanks, was on Repatha for 3 years with no side effects. Wish I’d never had it, not having another. Wondering how long it takes to leave my body."

• She...
• Taken for 2 to 5 years
• October 26, 2024

For High Cholesterol "Two weeks after my first injection, just out of the blue, my right hip started aching. Then it got to where it felt like it was catching and caused a sharp pain, keeping me from walking correctly. X-rays showed arthritis, but it still bothers me. Then my legs started burning, tingling, and hurting, and by the end of the day and when I first get up in the morning, I am so stiff. I’m due for a 5th injection in December, but I’m seriously thinking of canceling it. My cardiologist will probably throw a fit. It has lowered my cholesterol level a lot, but I’m tired of being in such pain just to go grocery shopping."

• Gti...
• Taken for less than 1 month
• October 3, 2024

For High Cholesterol "Had first injection 9/19/24 with just a slight burning sensation. Monday 9/30/24 mild muscle aches and spasms in arms, shoulders, legs, and lower back. Thursday 10/3/24 moderate muscle aches daily with difficulty sleeping. I eat a healthy diet and work out several times weekly. Hopefully, the side effects will subside, and I can continue my workouts without pain and discomfort. Since I just started the program, I will stick with it until the second injection. Am not sure if I will complete the program."

• Lin...
• Taken for 1 to 6 months
• August 25, 2024

For High Cholesterol, Familial Heterozygous "First off, I do have fibromyalgia and Sjögren’s, but after the first shot, the pain definitely went up, and I had chronic bronchial congestion. After the second shot two months ago, the pain accelerated in my knees, feet, legs, sides, chest, shoulders, and wrists. And I still have lots of congestion. I attributed the severe pain to the injection which, of course, as many say, did really help my cholesterol numbers greatly, but my next shot is in December, and I think I may not bother with it as the pain and anxiety that I attribute to the shot are not worth it. Reading these reviews and other reviews of this drug, it sounds like it just causes incredible mental muscle stiffness and congestion for many people. It works well for what it was designed to do: lowering all the numbers, and I appreciate that, but this is tough being in pain."

• you...
• Taken for 1 to 2 years
• October 2, 2024

For High Cholesterol "No problems with the injection site, only sore for about an hour, then nothing. As for the side effects, I seem to get a cold 3-7 days after the injection. Once very severe, with coughing, but my last injection only produced a runny nose and some upper chest congestion. I have BPH, so it is hard for me to determine if some burning and slight pain is caused by the BPH or the injection. As for my LDL, it has been reduced by about 30%."

• Let...
• Taken for 6 months to 1 year
• January 30, 2025

For High Cholesterol, Familial Heterozygous "Initial lowered cholesterol, but later injections, severe rash appeared many days later, size of lemon at injection site. Very sore, red, and itchy, lasting many weeks. Antihistamines helped, as well as cold compression."

• Sus...
• Taken for 1 to 6 months
• May 25, 2023

For High Cholesterol, Familial Heterozygous "Have had significant hair loss. Pain in legs and knee joints. Both knees have cartilage and meniscus damage, with no previous history of knee injury or knee-related issues."

• San...
• September 4, 2024

For High Cholesterol "Two weeks after the first injection, I developed pain in my hips, lower back, ankles, feet, hands, including toes and fingers, burning with urination, burning in my eyes, fatigue, and headaches."

• Ifr...
• Taken for 1 to 2 years
• February 23, 2025

For High Cholesterol, Familial Heterozygous "Reduced LDL, now listed as too low. UTIs, leg pain, hand nodules. Have to wait out the 6-month dosage to eliminate it."