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Imiquimod topical for Human Papilloma Virus User Reviews (Page 4)

Brand names: Aldara, Zyclara

Imiquimod topical has an average rating of 7.1 out of 10 from a total of 257 reviews for the treatment of Human Papilloma Virus. 61% of reviewers reported a positive experience, while 20% reported a negative experience.

Reviews for Imiquimod topical

  • Mendis
  • Taken for less than 1 month
  • July 22, 2015

"This right here is magic. I saw result on the 3rd weeks, warts got a lot smaller, didn't experience any burning just some mild itching. During the first week of imiquimod, the warts seem bigger than it was before but this is probably just routine as the warts eventually reduce in size since the beginning of the second week. End of the 3rd week, I'm almost cleared up."

10 / 10
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  • Phojoh
  • February 10, 2020

"Before using this cream I had tried getting the warts frozen off and also using apple cider vinegar, the freezing sessions didn’t work and although the apple cider vinegar reduced them slightly they weren’t completely going away. I got given this cream after going to a clinic for some advice, I can honestly say it has completely resolved the problem. The first few days I didn’t really notice any changes, maybe even some itching. But after about 2 weeks the warts were half the size, now I’m on week 4 and the ones on the outside of my vagina have completely gone. I have a few left on the inner by the opening but the doctor was right in saying If you treat the outside ones the ones inside will follow, I had no pain using this product either a lot of people mentioned blistering and irritation of skin but my experience is that the cream just gradually reduced the warts till they were gone. Worth the money."

10 / 10
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  • Faith
  • Taken for less than 1 month
  • June 5, 2018

"I never write reviews for ANYTHING, however I felt it that necessary to save someone from making a bad decision. Before I took this cream I went to another website with mixed results for the use of the cream. Despite seeing bad reviews I figured I was healthy so I proceeded to use the medication. Please anyone considering to use this medication for small genital warts (GW) .... DON’T! It literally activated the herpes simplex 2 virus that I wasn't aware I had lying dormant in my system. I regret not going to my usual GYN doctor because he said he never prescribes this medication because of the horrible side effects. he said little GW such as those go away on there own or could be taken care of through over the counter medication, which is way less harmful. If this review stops one person from making the life altering mistake I have made I’ve done me job. Please do your research and do not take this medication."

1 / 10
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Frequently asked questions

  • Ughhh...
  • October 2, 2016

"I went to the doctor 5 days ago and was told I had GW and was prescribed this cream. The first two applications I used, I was worried cause I didn't feel any burning or itching everyone had been saying they had felt but after the third application I woke up in AGONIZING PAIN, possibly the worst burn I have ever felt. And itching too(which I can't even itch because it burns so bad.) I literally can't stop crying because I just want this to go away so bad but I can't deal with how much pain I'm in as I type this. Please tell me what to do to make this burning go away!! I also haven't seen results yet but it's only the third application so I'm not too concerned... just praying this pain gets better. I know it will be worth it but still."

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  • Olivia
  • November 16, 2020

Aldara (imiquimod) "This cream Aldara works! 2 weeks in, using it 3 times a week with rest days in between and they have all gone! I experienced a lot of itching and a slight bit of soreness and stinging when going to the toilet but honestly, it wasn’t bad at all. I used vagisil in the day time once I washed the cream off and that was my saving grace. I didn’t feel anything or notice a change until using the cream a 4th or 5th time so just be patient and just cause you’re not in excruciating pain like people say, doesn’t mean it’s not working!! I guess I was very lucky in that sense."

10 / 10
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Are you taking this medicine?

  • Painful...
  • Taken for less than 1 month
  • November 26, 2015

"I used this creme for three days after being diagnosed with genital warts (HPV) the next day I was in so much pain in my genital area. My small itchy warts turned into big white sores. It's been 5 days since and the pain was so unbearable that I went to urgent care where I was told I had chemically burned my genitals. They told me that I was just suppose to put a small amount on the infected areas, but I had placed all over for " preventable measures" if you use this creme use as little as possible. I'm still so much pain. I have trouble sleeping and walking. Peeing is really painful.This creme made my situation much worse. Use with caution"

2 / 10
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  • jackie
  • October 22, 2019

Aldara (imiquimod) "Prescribed Aldara after 2 failed rounds of cryotherapy for Genital Warts (GW) after being diagnosed with HPV about two months ago. Struggled mentally with GW as there were a few clusters and two very large ones, especially after the failed cryotherapy, and wasn’t sure about Aldara after reading reviews, but I’ve been using it 3 times a week in the evenings for one week so far - one large GW has gone and the majority of clusters. Prescribed to use it for 4 weeks, but after being one week in, not only have the GW’s improved but so has my mental health. Fair amount of itching and occasionally pain when urinating, as well as soreness after the first couple of applications, but nothing compared to what some people seem to have experienced. Could not recommend more, and I wish I’d gone straight for this over the cryotherapy! (Only giving 7/10 as I’m one week into treatment, don’t want to jinx it, and there has been some discomfort)"

7 / 10
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12 Report

More FAQ

  • Calig...
  • Taken for less than 1 month
  • November 22, 2016

"Have been using for almost a month. Have had about a dozen dark brown, non raised warts around the base of penis and pubic mound for about a year. . Anyways they are slowly lightening in color and seem to be going away. Even being moderately careful Ive had a few sores and severe itching(nothing too horrible). Make sure to use a q tip and apply a ball point pen tip sized amount to the wart only. Even then you can still get some cream on healthy skin and cause small sores. I am confident that this cream will eventually kill all the warts slowly but surely. Dont be afraid of the cream, just respect it. I believe all the people having horrible side effects put entirely too much on. This isn't a medication that you just slather on!!!"

8 / 10
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  • Why
  • January 5, 2019

"So I was told I had a few little warts near my vagina and butt after I gave birth. I wanted to try something a little less dramatic than the acid so I opted for the cream and now I wish I had just let her use the acid. The first time I used it was no big deal. It was after the second time that I started to feel the burn and itching. I figured it was no big deal a minor side effect. The next day I had a doc appointment she looked at it before my pap and told me it looked fine. Then I went home used it for the third time and that will probably be the last time. The day after I woke up to complete burning and itching everything hurt sitting walking peeing evening taking a bath burned like hell. I look one look at my vagina and it was red swollen it looked almost like I had been burned. The pain is so bad I took a shower and cried the entire time. DON'T USE THIS CREAM. You will find a bunch of other women say this cream did nothing but cause them pain. I wish I had done my research."

1 / 10
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  • Landor
  • Taken for 1 to 6 months
  • July 25, 2019

"Hetro male 33. Have HPV warts on my pelvic area (5), 2 on my penis shaft and 2 on my scrotum. Very depressing. Been using this cream for a month and my warts have not gone away, they seem to have gotten a bit bigger. I do not feel any tenderness on the areas where I have applied it and no redness or burning. A slight itch is all. Will continue to use for the recommended 4 weeks total and keep updating."

1 / 10
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  • User
  • Taken for less than 1 month
  • September 25, 2018

Aldara (imiquimod) "I’ve been using Aldara for just over 2 weeks now for anal warts. The sachet with the cream is so small that I assume you just used one entire packet however upon reading reviews people started with less and worked their way to more. I have had no flu or nausea symptoms but I got open slightly bleeding blisters leaking a lot of fluid around my perineum and on the outer rim of my anus. I have to have some absorbent material there 24/7 or it becomes too wet and irritated. However the warts themselves have gone from cauliflower to tiny barely recognizable bumps in the tiny amount of time I’ve been using it. So it has worked but my body was definitely not ready for the dose I applied. Recommend starting small amounts using cotton swap onto direct area and using more from there once your body is used to it"

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  • Mjjan
  • Taken for less than 1 month
  • July 4, 2015

"I had a few small GW right at the opening of my vagina. The doctor prescribed imiquimod 3x a week for 6-10 hrs. HOWEVER she told me that I could get about 2-3 applications per packet because I didn't have too much. I applied VERY small amounts. Like I'm talking about a grain of rice on a q tip small. I got about 4 applications from one packet. The 2nd night I think I might have put too much on and I woke up with a swollen throat and a weird taste in my mouth and swollen armpit lymphs so thats when I decreased my dose amount. After that I had no side effects except for a small swollen armpit lymph node. NO PAIN NO ITCHING NO SCABBING. Just used vaseline before applying and took vitamins C and D everyday. Now about 3 weeks in I'm wart free."

10 / 10
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18 Report
  • Person
  • Taken for less than 1 month
  • December 11, 2019

"I was prescribed this imiquimod medicine for HPV and wish I would have been given better instructions! I used two doses and am in the most excruciating pain I’ve ever been in. You only need a little bit and only on the warts themselves, NOT all around them!! I made this mistake and have been experiencing nausea, loss of appetite, tenderness and pain on external genitals, body aches, chills, headache, fatigue, Swelling, all the symptoms that you DON'T want a medication to give you!! I think if I had been given clear instructions on how much to actually use, I don’t think I’d be in this much pain and agony. It hurts to walk, sit, go to the bathroom, the only time it feels better is when I’m in a warm bath. If you are prescribed this DO NOT use the whole packet!!!! I hope this helps so nobody has to experience the same thing I am!! OUCH!!!"

3 / 10
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  • Ruined...
  • Taken for less than 1 month
  • September 23, 2018

"The first application went well but the second application - idk what happen but I'm never using this cream again. Then I had the chills followed by a 101.7 fever. My labia also started to swell. This flu symptoms lasted another day and then completely stopped. But now my labia is so swollen, I can’t even see what’s inside anymore. I went to the hospital they prescribe me antibiotics and said I now have a severe yeast infection when I didn't a few days ago. It hurts to urinate. It hurts to walk. It hurts to move. My labia still burns like hell and it makes me want to cry because when I look down at my inner thigh my skin looks ruined. I think the doctor used me as test dummy for this cream."

1 / 10
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  • Condoms...
  • April 10, 2019

"Stock your liquor cabinet, it’s gonna be a long 2 months. When I first started using this medicine, I had virtually no symptoms. Warts were falling off (the medication seems to dry the warts out and they fall off), I felt great, life was amazing. Then about 2 weeks in, Body aches, nausea, diarrhea. That lasted for 2 days. Then the skin started to blister and bleed. Putting on the medication made me scream. When it started to burn when I peed, I decided to take a 3 day break from the medication so my lady parts could heal up. 3 days later, my vagina still looks really bad , but I can sit down without dying. We apply the cream again. Hurts like a son of a gun, but the next morning more warts are gone. Cool. I’ve got this. Currently it’s week 4 of the medication: I have 2 stubborn warts left, halfway through medication, my vagina still looks scary, and peeing no longer feels like childbirth. It works."

9 / 10
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  • Cam
  • Taken for 1 to 6 months
  • April 25, 2020

Aldara (imiquimod) "Best tip is use a feminine itch cream and Vaseline with the cream. Use the itch cream after and cover any close skin with Vaseline. This is my 3rd time using this cream. The first two times were absolutely easy for me. The small tiny warts near my vagina went away within a WEEK TOPS. Sadly, this past time was absolutely awful. The location & size definitely determines how the ride will be. I had two baby pimple size one on each sides of vagina in the crease of my thigh. It has been a long 2 months and I've went through bleeding, itchiness, skin color change and everything else. They’re finally gone and I’m just thankful I have a loving boyfriend who was supportive and patient with me. Sadly my vagina looks so different but I’ll take it if it means no warts for a while."

6 / 10
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  • WhyMe
  • November 3, 2015

"I've been using this cream for 5 days now for anal hpv. Last night was the first night I skipped a treatment and I'll reapply it again tonight. I'm using it 5 x's a week. I have yet to experience the horrible reaction a lot of people complain about. And I've been using an entire packet of the cream. It seems to be working different on everyone because everyone's immune system is different but I'm HAPPY to say that aldara appears to be working. In just 5 days I can already see the warts getting smaller. They are kinda red but they aren't painful just a little tender. No bleeding and no horrible side effects. Don't be afraid to use it. If u start getting bad side effects use less cream and space the days out more."

9 / 10
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  • ashash
  • Taken for less than 1 month
  • March 4, 2015

"This drug is incredible at getting rid of warts. But I would DEFINITELY recommend using it for one day then waiting 3 days to see how severe your reaction is. I used it on 2 days before getting any reaction, and boy it was a huge reaction. Even the TINIEST amount of aldara causes your vagina to literally swell and burn for days and cause blisters and I used the stuff very sparingly and only on the warts. For anyone about to try aldara please just try it once and wait 3 days to see how you react before applying any more because man this stuff is strong!!!"

10 / 10
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  • Jake...
  • Taken for 1 to 6 months
  • November 12, 2013

"After only being on this medicine 3 weeks, I have noticed a huge difference as my warts are all gone except for one, but it's so tiny & shriveled now that I don't think it'll last much longer either. During the first week/week and a half of using the Aldara (Imiquimod) Cream, I didn't notice much after applying the cream except that the warts got very red & stood out even more. This was a little distressing, but within a few more days the area on and around the warts started flaking up & falling off sort of like a healing scab. There have been some side effects of redness, slight rash, & itching, but Gold Bond powder daily & neosporin occasionally really have helped. One more week left this round, & will use it again in a flash if neeeed."

10 / 10
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  • Christi
  • Taken for less than 1 month
  • April 8, 2021

Aldara (imiquimod) "I was exposed to a lying partner. After we had sex I developed a wart 30 days later. One month later I was given aldara. I was prescribed three nights a week for six weeks but my warts came off after two applications. I continued the medication as my paranoia of HPV —naïvely-was greater than the damage aldara could cause. At week three I had ulcers on my vulva and severe erosion. My doctor told me to stop the medicine. nobody warned me that dormant autoimmune diseases can be set off permanently by the medicine. I now have lichen planus on my vulva for the rest of my life. do not take this medicine allow your body to naturally fight off the warts! that is what I wish I had known then."

1 / 10
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  • Anony...
  • Taken for less than 1 month
  • August 9, 2019

Aldara (imiquimod) "I'll use Aldara 3 times a week. I recently used it for the 2nd time and warts on my penis already started shrinking, some are gone too. I didn't experience any side effects so far but I got mild flu like symptoms. Expensive medicine but definitely useful, very quick to effect."

10 / 10
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  • jen
  • Taken for 1 to 6 months
  • July 18, 2019

Aldara (imiquimod) "4 weeks in and only one wart has shrunk. Most have stayed the same and I have actually had lots more warts appear despite taking really good care of myself. The side effects are horrific - I have red raw patches that feel like blisters and burns on my inner labia, which is odd because I've not applied the cream there and have no warts there! It is difficult to sleep at night because of the pain and itching. I've used warticon in the past and had a much better experience - Aldara feels like I'm just putting acid on my genitals without any reward or success!"

2 / 10
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  • GW GW
  • January 31, 2015

"Initially I was worried that this treatment wasn't working because I didn't see immediate results after the first 2 applications. After a week, however, I saw significant reductions in the size of my warts. And now at week 3 you can barely see anything at all. At first I was very distressed about the extreme side effects I had (severe itchiness, erythema, some bleeding), which were very concerning to me. They did subside, however, by the 4th or 5th application of Aldara. My advice would be to not give up! Yes, it is very itchy and somewhat painful with the first few applications but the side effects do subside and the effects are significant. Just be patient and you will see results."

8 / 10
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  • Older...
  • October 30, 2019

"I've been using the imiquimod cream 3 x weekly for a month for HPV. No side effects yet (grateful). I have a few tiny warts and the meds keep them at bay. Also one spot a cluster. Told by docs it's a mild case. The cream have yet to make a huge difference. I'm hopeful it will soon. I do feel prickly and bothered there. This started about 6-8 months ago. I do feel dirty and not sexy... At all :( Good luck and sending healing vibes.."

6 / 10
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  • Seein...
  • Taken for less than 1 month
  • September 2, 2017

"I'm a 37 year old female recently diagnosis with low risk HPV or genital warts. After much crying about this diagnosis my doctor decided Aldara would be best so I could see the warts start to disappear. I chose Mon, Wed and Friday to be my treatment days. It's been one week and I can no longer see or feel any warts and I am both amazed and relieved! I will continue to use this product for additional week just to make sure everything has cleared. Thank you Aldara! I read some horror stories concerning the side effects and I'm guessing I'm one of the lucky one cause I never had any real severe side effects. I did have slight irritation, redness of skin, and very mild itching. Aldara worked for me!!!"

10 / 10
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13 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

Learn more about Human Papilloma Virus

Symptoms and treatments