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Imiquimod topical for Human Papilloma Virus User Reviews (Page 3)

Brand names: Aldara, Zyclara

Imiquimod topical has an average rating of 7.1 out of 10 from a total of 257 reviews for the treatment of Human Papilloma Virus. 61% of reviewers reported a positive experience, while 20% reported a negative experience.

Reviews for Imiquimod topical

  • Nordi...
  • Taken for less than 1 month
  • November 30, 2016

"Imiquimod is amazing! I found out I had HPV last week and I had one small wart plus some textured ares where it seemed as if more were forming. I was prescribed Imiquimod and one week later all of the texture is gone, the area is smooth and the one raised small wart is pretty much gone! I had no side effects other than a little sensitivity and "rawness" on the site of application but totally worth it. However, I have been taking very good care of myself: eating well, and getting sufficient rest so I can boost my immune system to help fight the outbreak. It's nice to feel back to "normal"."

10 / 10
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  • Happy...
  • Taken for less than 1 month
  • December 16, 2016

"So, I have to admit I was really surprised when I was diagnosed with HPV. I had had two sexual partners, kept up to date on regular Pap tests, and even received the most recent vaccines against the virus (gardasil 9). But it happened. I found one abnormality inside my vaginal opening. It didn't even really look like a wart, it was so small. But. It wasn't there before. So I went in to see my doctor, and yep. Low-risk Hpv. Prescribed aldara. I was told to apply it daily for one week. After the first four applications it was almost gone! Very happy. But. Because of the location, it chemically burned my skin in nearby areas. Very painful. But it works! I also eat healthy and take vitamins. My boyfriend was incredibly supportive as well."

9 / 10
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  • XXX
  • Taken for less than 1 month
  • March 28, 2020

Aldara (imiquimod) "In the first week of using this cream I felt no difference, although now I’m in my second week ( I apply mon, wed,Fri for 16 weeks) and I’ve got a sore throat and sneezing, also down there BURNS and ITCHES like anything!! I’ve noticed swelling around the surrounding area of the wart (I only have one) but I have noticed it’s decreasing in size slowly but surely ! To reduce the itchiness, take two showers per day ( no scented shower gels) to keep them clean also if you can don’t wear underwear as the friction can make it more painful. For the pain whilst urinating , take a cup or jug and rinse off with cool water! Although the pain is unbearable sometimes ,try and stick it out. :)"

10 / 10
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Frequently asked questions

  • allbe...
  • June 27, 2015

"3 weeks ago after seeing my Dr about some weird "bumps" on my vagina I got the devastating news that I have HPV. In tears walking out with my prescription for Aldara I was in too much shock to recall what my DR or pharmacist said about applying this very pricey cream. I came across this site and the more I read the more scared I was to use it. I'm sorry for those that had severe side effects but I think it is important to note how effective and great this medication is and how it can work well if used properly!! I only applied it to the warts, used vasoline around on the healthy parts and took benadryl with it at bedtime. In the morning I was sore swollen and sensitive, however it was tolerable. 3 weeks after using it the warts appear gone!"

10 / 10
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  • K94r
  • February 6, 2015

"I started trying with home remedies to get rid of warts (Acv) but saw no results. When I was prescribed imiqumod I was not very diligent about applications but saw some small results. However, I refilled my prescription and began to follow the 3 day a week regimen and after 3 weeks even the largest warts have subsided. There was some intense irritation (reason for the 9 out of 10) but as long as it is only applied where needed and washed well, the results are great!"

9 / 10
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  • 24234...
  • April 9, 2017

"Absolutely awful. Reaction to this was so bad I was told I almost 100% had herpes (due to Aldara causing severe blisters). Made it 3 days with this medicine and started to have severe vaginal swelling to the point where I had to sit in a warm bath to urinate or dump a water bottle on myself while going (TMI). Stabbing pains, nausea, could not sleep, rawness like I never knew was possible, missed a week of work because I could not even move after I had stopped using it. Took about 2 weeks, 4 doctors appointments, countless tests for various STIs/STDs for my body to fully recover."

1 / 10
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  • 40s Mum
  • Taken for less than 1 month
  • August 12, 2016

Aldara (imiquimod) "I had 3 HPV near my V opening, went to see my gyne. Had it checked and she gv me a box of Aldara, Probas Omega 3 AEE, Protexin Protect Multi Prebiotic. The doc explained treating HPV (skin tags, warts) must be done both ways, frm inside and outside due to low immune/anti body system inside us. Aldara is for skin app, 3x a week (Mon, Wed, Fri). Apply while lying or sit down - allow it to absorb for a while before sleep at night. 1 sachet perweek. As for the Omega 3 & Protect, 2x a day. On top of that, double up my norm 1000mg VitC and MultiV. All these for 30 days. Aft 2 weeks, it completely gone. Balance of Aldara, will keep if any for future."

9 / 10
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More FAQ

  • Anony...
  • June 30, 2015

"To all of you using this drug for your warts, I want you to know that there is a light at the end of the tunnel. Your love life DOES continue... And you should not be worried. 90% of all cases clear up for good within two years, and for those that don't, Aldara is a powerful medication to finish it off (Not a cure!). I had that lasted for three years until finally a doctor prescribed me Aldara on Dec 11, 2011. For the first eight weeks, nothing happened (as is common for male treatment), but my doctor seemed to be disheartened by the lack of progress and opted to have them frozen off. A week later I finished the remaining four weeks of treatment. The affected area was red and painless. My doctor finally told me... "You're cured.""

10 / 10
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  • Happy...
  • December 2, 2015

"I was diagnosed with anal HPV last month. This week will be my 5th week on this creme and since last week I noticed my GW are gone! I didn't have serious pain, but there was some redness, itching, and mild pain, but that's how u know it's working. The goal was "irritation" my doctor said. I used it 5x's a week before bedtime for 3 weeks then when it got irritated I went to 3 x's a week. I used the entire packet at each application and rubbed the creme into the wart and surrounding skin. I did get itching about 4 hours after application. In the mornings I washed it off. I'm happy this medicine worked for me. Don't be afraid to try it."

10 / 10
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  • A Guyy
  • November 10, 2015

Aldara (imiquimod) "Contracted GW and went to dermatologist who diagnosed them after one before misdiagnosed them. Had them burned (electrocuted off) and frozen. Had to return two weeks later as many more small ones had grown, same treatment again. I was then prescribed Aldara for a month, morning and night for 5 day stints (Mon-Fri). I kept up with this first week but second week I started just doing nights as twice a day seems excessive after reading everyone else's prescriptions. Things look much clearer but I got a blister which healed significantly after taking a break for a few days. This stuff takes a few days to kick in but expect to be pretty red and your scrotum to be sore if you're a guy. I'll repost in a couple weeks when I'm done my treatment."

9 / 10
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  • Jano
  • Taken for less than 1 month
  • July 19, 2019

"Gay Male, 29 years old, anal Warts, Imiquimod 5% worked great for me. I recently discovered some anal warts. I talked to my pcp and we decided to give the imiquimod 5% creme a try after freezing didn't work well. I applied the creme 3 times a week (Mon, Wed, Fri) before bed. Within a week I noticed a huge improvement in the size of the warts. After two weeks, the warts were completely cleared up. (one had been quite large initially) I didn't experience any of the major side effects. Its difficult to contain the creme to just the wart when applying and rubbing it in. I did notice some light itchiness the first week and I did wake up groggy and stuffy. I made sure to take lots of vitamins which seemed to help. Both outbreaks were huge blows to my self confidence, and finding an easy at-home treatment that worked for me was a huge relief."

10 / 10
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  • Smurf...
  • Taken for less than 1 month
  • February 3, 2019

Aldara (imiquimod) "Black female aged between 24 and 28. Used Aldara for about 1 month, 3 times a week- Saturday, Tuesday and Thursday and washed it off after 10 hours. The wart was on my perineum area. First week on this medication made the wart increase in size, bummer. However, by the end of the second week, the wart had drastically reduced in size. For the first two weeks, I used a whole sachet for each application (realized later this was some sort of over dosage) and might explain the on and off sore throat I experienced during this time. Reduced my dose for the last two weeks- one sachet for 3 applications. In total, I ended up using 8 sachets from the recommended 12. Keeping the rest in case of any re-occurrence. Strangely enough, I only experienced burning and irritation on the last two weeks when I was using a more reduced dosage. There's also minor discoloration where the wart was."

10 / 10
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  • Lani
  • July 5, 2019

Aldara (imiquimod) "I developed genital warts (GW) on my vulva going in my vajay jay. I was prescribed Aldara using it (Mon, Wed and Fri) for 16 weeks at bed time. I noticed change on my seventh application. The end of that third week 95 percent of my warts were gone. And the rest were gone in my 4th week. I am now free from GW but my Doc says I must continue to apply aldara until 16 weeks. I don't have any side effects , only headaches in first three weeks of using Aldara. My Doc also told me to apply vaseline on the skin that isn't affected around the warts before applying Aldara cream on the warts. I found this cream amazing and I am happy. The only thing its that , the cream is bloody expensive."

10 / 10
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  • Anon
  • March 13, 2016

"I had about 13 small warts around my anus and opening to the vagina. I was prescribed Aldara (Imiquimod) and told it would fight the virus from within and was better than freezing them off. My doctor had said that it could possibly take up to three months to work. Well, only two applications in and theyre almost gone! I cannot believe they are disappearing so quickly. I had read many horror stories about the side effects, itching, sores, etc. My own experience is that, yes, it does get very itchy ( I resisted the urge to scratch) but that itch lasted for approx. an hour and then dies down. I had no burning sensation but i guess it depends on the individual. Overall, I am thrilled with the product. The expense was worth it."

10 / 10
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  • ConCon
  • February 14, 2017

"So I want to help everyone out there who hates the way these things look. So the other day I was looking in a handheld mirror at my warts and started to scratch them. I realized I couldn't feel it when I was touching the wart its self! I then proceeded to pinch off as much of the wart I could grab. It bled a little but I didn't feel any pain! I let the cut heal for a few days then used the cream once and I've never seen better results! THE WHOLE WART IS GONE! I DIDN'T HAVE TO WAIT FOR IT TO SHRINK IN SIZE! Now I do not know if this is safe or recommended but I figured if I went to get them surgically removed then they'd basically do the same thing but with a scalpel and charge me a lot! Good luck and let me know if this works for anyone!"

9 / 10
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  • Girl
  • Taken for 1 to 6 months
  • June 28, 2018

Aldara (imiquimod) "Aldara works wonders. I used it as prescribed and with in 2 weeks, most of the really large lesions were gone! The only downside to Aldara is the side effects. The itching, swelling and redness around the affected area was almost unbearable! I’m on my 5th week of treatment and honestly, I can’t wait for this to be over"

9 / 10
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  • Caz
  • Taken for 1 to 6 months
  • April 6, 2020

Aldara (imiquimod) "I noticed small lumps on the inside of my labia. I went to my gyno who confirmed they were genital warts. My gyno prescribed Aldara cream 2 times a week for 6 weeks. The cream caused intense itching in the area, soreness and ulcers in and around the area. I also had headaches, very fatigued & flu-like symptoms. After the 6 weeks, the warts have gotten somewhat smaller but had not disappeared, as it had somewhat worked I asked my gyno if I could get another dose of the cream. I went through another 6 wks of the medication and finished up about 2 wks ago. Aldara did significantly reduce and clear most of the warts but there is still some of them there and 2 wks after finishing treatment, I felt itchy down there again and noticed warts growing back again. I am sad as I went through so much pain physically and emotionally. I can imagine the treatment does work for some patients so it is worth a try, sadly it just didn't fully work for me."

5 / 10
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  • KQQ
  • July 1, 2016

"Best medication ever if used correctly! Have HPV and had about 6 small warts around vagina/inner labia for almost two years. I was embarrassed to address the issue but after this experience wish I would've spoken up sooner. The key is using a TINY amount. I applied to the tip of each wart with a q-tip every other night. Keep OFF your healthy skin - all these negative reviews are from people applying it liberally. This isn't like Neosporin, people. Read the warning that comes with the medication. My warts cleared up one/two at a time and in no more than two weeks. The discomfort was minimal. Slight tenderness mostly. It has been almost 3 years and they haven't reappeared. I have a few common warts on my hand so I'm trying it there, too."

10 / 10
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  • Sara
  • Taken for less than 1 month
  • February 18, 2020

Aldara (imiquimod) "I found out I have genital warts and they were pretty much a lot to do any other treatment so the doctors suggested me topical cream. At first I was scared when I read all the reviews first 3 applications I didn’t feel any difference but the day after my third time I started feeling like I had a cold or cough and next day morning I had a hard time peeing as I was burning like anything. I found a trick I started sprinkling water cold water on me before I start peeing that made me not feel 95% of my pain peeing. And in 1 day my burn pain while peeing was gone and I saw 50% of my warts have disappeared I’m still a little sick but I’m happy"

9 / 10
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  • Anonn...
  • November 2, 2016

"Okay if you're here before you have applied the medication, GOOD JOB!! The worst mistake I've ever made was not reading reviews before I applied this medication. The first couple of days I had AGONIZING pain because of the severe burns I had all over my vagina... and that is because I spread it all over. Be very careful when applying this medication. Just put a little amount on the tip of a Quitip and apply it on the wart only. If you do experience burning or itching, use neosporin, aloe, or any other numbing/pain relieving cream!!! Also apply the cream before you use the application and that will help you too. Other than that this cream does work, it takes time but it works. Don't lose hope!!!!"

8 / 10
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  • Lady
  • Taken for 6 months to 1 year
  • July 23, 2019

"imiquimod really does the job for HPV warts. The only problem was when I first used it for warts. I did not know that a little goes a long way. Since I used too much, my skin didn't react very well and it was stinging. I let it heal and began using the cream, but less amount. It works so well. The warts go away in about a week and a half or 2. I don't get then much. I've had HPV for about a year and I just catch the warts early and apply a tiny bit of cream and they're gone. I'm glad this was given to me (: Highly recommend. HPV is a bit deteriorating emotionally so medication to help rid of symptoms is really nice."

9 / 10
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  • found...
  • Taken for less than 1 month
  • November 24, 2016

"The Only thing that relieves the pain from this cream 100% is prescription lidocaine ointment usp 5% it only takes a small amount and works within seconds! I can finially sit and walk without cringing. It last about 5 hrs. I don't see why drs don't automatically give you this when the aldara is filled !"

10 / 10
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  • Rachel
  • Taken for less than 1 month
  • February 4, 2014

"I developed genital warts while pregnant and was given this cream. When I first applied the cream it didn't itch, it only itched when I woke up at 4am to pee (pregnancy bladder) so I went ahead and washed it off after 5 hours every time I used it. I've only used it twice and my warts, I had a couple big ones and some small ones, are almost totally gone! The itching was bearable, but the key to it being bearable and it not driving you insane is using VASELINE! USE VASELINE WITH THIS PRODUCT! I applied vaseline to the skin around my warts to protect it from this powerful cream, and have no redness or irritation."

8 / 10
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  • Girlg...
  • Taken for less than 1 month
  • August 30, 2017

Aldara (imiquimod) "The Dr said I had genital warts and put me on Aldara and said I should use it for 4 weeks, thrice per week. I only used this cream once and within two days the warts started disappearing and within four days it had cleared totally. I used just a pea sized amount and applied it with a cotton swab directly on the warts. It did get a little uncomfortable and itchy after about three hours."

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  • Byker
  • Taken for 1 to 6 months
  • January 28, 2017

"Have dealt with gw at base of and on penis shaft for over 6 yrs. First had surgical excision but soon returned. Used otc wart freezing many times with minimal success and actual rebound wart growth. Finally was prescribed Imiquod 3 times weekly. Dramatic results. Started showing "activity"..shiny, liquid-like appearance on warts within a week. After 5 weeks the 2 large masses are almost completely gone. Normal surrounding skin does get red and inflamed, but quickly heals. (I also use selenium 200mcg daily and cimetidine 800mg 2daily). Keys are in patience and meticulous, careful, application. Apply only to lesions. Apply after gently washing area. Do not over apply, do rub in and then gently clean surrounding tissue with damp q-tip. Works"

10 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

Learn more about Human Papilloma Virus

Symptoms and treatments