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Vascepa and Pain: What Users Say

Pain: mentioned by 11 users (9.2%)

Based on user experiences from 119 Vascepa reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

joint pain 10.1%
pain 9.2%
muscle pain 8.4%
diarrhea 4.2%
heart palpitations 4.2%
shortness of breath 4.2%
gout 3.4%
back pain 2.5%
bloating 2.5%
constipation 2.5%

Reviews for Vascepa

Commonly mentioned side effects
  • Nan...
  • Taken for 1 to 6 months
  • July 20, 2019

For Hypertriglyceridemia "I started Vascepa on April 27th for high triglycerides. After 3 weeks, I started with horrible ankle pain in both ankles. I had been on vacation and attributed it to walking on the beach. It did not go away and after another couple of weeks, I started with joint pain in both knees and flu-like symptoms. I told my co-workers I felt like my legs weighed 100 lbs each. I could hardly make it through the day. On July 9th, I started researching Vascepa as it was the only thing different in my meds. I even was scared I had something like Lupus or Fibromyalgia. Imagine my relief when I saw that the main side effect was joint pain!! I discontinued the Vascepa on July 9th and 10 days later my ankles and knees are pain-free, and I can sleep again!!! It doesn't affect everyone the same way, but for me, I'm finished with it!!"

1 / 10
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133 Report
  • suz...
  • Taken for less than 1 month
  • November 6, 2019

For Hypertriglyceridemia "I took Vascepa for two and a half weeks. I developed severe hip and leg pain. It got to the point that I couldn't put any weight on one leg. I stopped Vascepa immediately when I figured out that it was the culprit. I'm praying that those side effects go away quickly."

1 / 10
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91 Report
  • suz...
  • Taken for less than 1 month
  • November 6, 2019

For Hypertriglyceridemia "I took Vascepa for two and a half weeks. I developed severe hip and leg pain. It got to the point that I couldn't put any weight on one leg. I stopped Vascepa immediately when I figured out that it was the culprit. I'm praying that those side effects go away quickly."

1 / 10
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91 Report

Frequently asked questions

  • Mou...
  • Taken for 1 to 6 months
  • October 29, 2019

For Hypertriglyceridemia "After taking Vascepa for two months, I have developed side effects of severe bilateral hip pain, buttock, and leg pain. Sometimes it’s so bad I feel like crying. I stopped taking it about a week ago, and the pain might be slightly better. I’m hoping it will go back to normal. I’ll be discussing this with my Dr. in a couple of weeks."

1 / 10
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61 Report
  • Dig...
  • Taken for less than 1 month
  • April 10, 2019

For Hypertriglyceridemia "Started causing bad leg pain and weakness in legs after about 3 weeks. Hip, knees, and finger joints started aching bad. Got where I was stumbling and too weak to move. Quit 4 days ago and am getting better now."

2 / 10
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61 Report

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  • Osl...
  • Taken for 2 to 5 years
  • September 17, 2019

For Hypertriglyceridemia "I was prescribed Vascepa for elevated triglycerides associated with HIV+. As I am on polypharmacy due to various unrelated conditions and many meds in my daily regimen duplicate, interact, enhance, or all three, the many side effects associated, my physicians and I are hard-pressed to attribute the cause of most of my discomfort. Recently, I developed terrible ankle pain (bilaterally upon flexion). Another review contributor here voiced the identical issue along with foci of seemingly arbitrary intense deep muscle pain (for me, this is in the right quadricep). Stopping all meds and reintroducing them in turn is not an option for me. Additionally, MDs are no longer trained in full; rather, specialty is rife with the lack of scope that results. As I don't feel that Vascepa is of singular need for my life and health, I shall share my thoughts with my PCP and then wean myself off this med with care."

5 / 10
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  • Cha...
  • Taken for 1 to 6 months
  • September 26, 2018

For Hypertriglyceridemia "Started with the recommended dose of 2 Vascepa twice a day. After about 4 months, the pain started in the hip - couldn't even lay on that side. To take a daily walk needed a support pole as pain would come suddenly. Went off, cleared up. Also, ringing in ears increased and 8 lb weight gain. Went off Vascepa - most side effects cleared up. Tried half dose a few months later. All side effects--plus came back. Never again! I am a female in my late 60s."

1 / 10
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39 Report

More FAQ

  • Sle...
  • Taken for 1 to 6 months
  • September 1, 2021

For Hypertriglyceridemia "I took Vascepa at my doctor's request. I am awake now at 1 AM because every muscle and joint in my body aches. I can now barely function during the day, the pain is so bad, and I wake up in the middle of the night numerous times to use the bathroom. My knee joints now crackle every time I sit down. My right arm, from elbow to wrist, is swollen, and I can no longer make a fist. I only took this medication for 6 to 8 weeks and had to stop because it felt like a cinderblock on my chest. I used to be able to take walks and ride a stationary bike. I can no longer do either. I am now doing a liver cleanse to try and get this stuff out of my body. If I don't improve soon, I don't know how I will continue to function."

1 / 10
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11 Report
  • Cre...
  • Taken for less than 1 month
  • July 25, 2021

For Hypertriglyceridemia "I started on one gram Vascepa twice a day a week and a half ago. My cholesterol is only 215, but my triglycerides are over 750. Yesterday I started hurting all over in most of my muscles and joints, even my ear, eye, and bottom of one foot. My hip is in terrible pain, although it was hurting previously, but not this bad. I'm not taking Vascepa again. Terribly expensive even with insurance."

3 / 10
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7 Report
  • Hig...
  • July 19, 2015

For Hypertriglyceridemia "I've been on Vascepa (2 pills daily) for about 7 months now. I went from 475 to 625 in three months. I don't know how my try spiked. Now I have stomach pain along with knee and back pain. I had back surgery 4 years ago unrelated to taking the drug, obviously. However, I do have some stomach pain when laying on my belly."

6 / 10
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27 Report
  • vin...
  • Taken for 1 to 6 months
  • December 27, 2018

For Hypertriglyceridemia "I think this drug thins your blood. After I started taking it, I had constant bleeding on my sclera of the eye. I didn't realize it was the medicine at first until I looked up the side effects. My knees also hurt."

1 / 10
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12 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.