Imbruvica User Reviews & Ratings (Page 2)

• Log
• October 12, 2020

For Waldenström Macroglobulinemia "My husband has Non Hodgkins Lymphoma and Waldenstrom Macroglobulemia, he had been treated with Chemotherapy in the past. He was leading a very normal and active life then last year in June 2019 he needed to be started on Ibrutinib, after the fifth month of treatment on the 30th of November 2019 he suffered a cardiac arrest at home. It was the most terrifying thing I have ever witnessed, I had to perform CPR till the ambulance arrived! He was in hospital for six months, he is home now and I am his carer as he suffered a Hypoxic brain injury as a definite result of Ibrutinib! The consultants in ICU said it was a direct result of being on ibrutinib, it is also written on my husband's discharge letter from hospital. I totally blame ibrutinib and now our lives will never be the same."

• Muki
• October 2, 2020

For Chronic Lymphocytic Leukemia "I've been on Imbruvica for only 6 weeks because of bad side effects my doctor stopped the medication. Since I started taking the medication in October 2019 and now is October 2020 still have the diarrhea. I tried all medications and some teas to stopped it. Really don't know what to do."

• larry...
• Taken for 2 to 5 years
• March 19, 2023

For Chronic Lymphocytic Leukemia "I was diagnosed with 4th stage Chronic Lymphocytic Leukemia in 2011. I was prescribed Imbruvica and I have been taking it for five years now. Imbruvica saved my life, my oncologist had given me one year to live in about 2016."

• irkee
• Taken for 2 to 5 years
• March 19, 2024

For Chronic Lymphocytic Leukemia "If my mother had had this drug, she wouldn’t have died of CLL 25 years ago. Wonderful drug. Very few side effects. Hard to know what symptom to pin on what (including age). I’ve maintained excellent blood counts, life activity, general well-being for 4 years now. Side effects: blood pressure, red spots under the skin of arms, slight decrease in energy, greater tendency toward bruising/bleeding, recent slight urinary incontinence. 420mg pill/day makes it easy to administer."

• Mfirmes
• January 9, 2018

For Graft-versus-host disease "About me: AML, stem cell transplant survivor with GVHD. How Imbruvica helped: I started imbruvica in 4/17. Prior to taking it I was completely debilitated. After 4 full months on the drug I noted marked improvement. Now I am able to walk, light lifting, and carry out regular activity with much less fatigue and pain. My skin GVHD is not showing any symptoms. It's been a god send! Side effects: I noticed cramping at about 5 months and back & joint pain at 8 months. The cramping became severe however it is managed well with tonic water. The pain is extreme at times - but so far outweighs the GVHD symptoms."

• Sad
• Taken for 2 to 5 years
• August 24, 2021

For Chronic Lymphocytic Leukemia "My husband did very well on Imbruvica taking one pill three times a day when he was switched to same dosage once a day within months he had a VF heart attack went on Life support never recovered never had cardiac issues or was told to get a cardiologist high BP and smoked I suspect the med but don't know for sure. My advice is get a cardiologist if you take this medication."

• Anonymous
• Taken for 1 to 6 months
• February 2, 2021

For Chronic Lymphocytic Leukemia "After 76 days on Imbruvica (420mg) my prostate gland was swollen to the point where urination was almost impossible and my colon was blocked. Also there was swelling felt in my lungs and heart. At times after taking the tablet I could feel my heart beating against my sternum. The day after I stopped taking the drug the swelling subsided. I no apparent problems existed on the first two lots of the drug (56 days) I attribute the probable cause to a contaminated lot. After three weeks my bodily functions seemed to be back to normal. On the follow-up Pet-Scan no improvement was seen on lymph nodes."

• Anonymous
• Taken for 5 to 10 years
• September 25, 2023

For Chronic Lymphocytic Leukemia "It helped my condition immediately. Previously I've had FR and BR treatments. I take it after dinner around 6:30 pm with a full glass of water. My only negative side effects are brittle nails with ridges. I've taken it for 7 years and 9 months. I'm a 71-year-old female with CLL/SLL."

• Wife
• Taken for 1 to 6 months
• February 17, 2022

For Mantle Cell Lymphoma "Imbruvica was added to my husband’s treatment for MCL after 6 months of treatment for gastric cancer. He tolerated the herceptin well but after initial infusions of Imbruvica he was hospitalized for respiratory distress with what was thought pneumonia. This drug wreaked havoc on his lungs . He left the hosp after nearly a month and was on oxygen for the rest of his life and a DX of pneumonitis caused by this drug. No more Imbruvica at that time, was treated several months w IVIG to help his O2 stabilize and it did, then his oncologist started him back on this same drug ! 3 weeks later my husband was dead from respiratory failure. I read that anyone with respiratory issues should not be treated with Imbruvica."

• Brook
• Taken for 1 to 6 months
• June 9, 2023

For Waldenström Macroglobulinemia "My father was diagnosed with stage 1 Waldenstrom macroglobulinemia in March 2021. He underwent chemotherapy and in January 2022 he was doing so well that they switched him to Imbruvica. By May 16, 2022, he was rushed via ambulance to the hospital and admitted to ICU on June 5, 2022. Sadly he passed away. I believe with all my heart this medication killed him within 4-5 months of taking it … They NEED to take this medication off the market… People are losing their loved ones quicker because of this medicine."

• Mike
• Taken for 2 to 5 years
• August 2, 2021

For Chronic Lymphocytic Leukemia "I've been on it a little over two years after relapsing from FCR in 2014, was in remission till May of 2019. I haven't had much in the way of side effects, mouth sores that can be controlled with mouthwash. My counts are all in the normal range & waiting on the results of an MRI I had for another issue to see what my lymph nodes are looking like."

• GGL
• Taken for 1 to 6 months
• December 7, 2018

For Graft-versus-host disease "Started Ibrutinib (Imbruvica) on 22/10/2018 (7 wks ago) for cGVHD (Chronic graft-versus-host disease) arising from stem cell transplantation (SCT) (matching female sibling) in 2014 to treat Mantle cell lymphoma (MCL). cGVHD (skin, eyes, mouth & subcutaneous tissue resistant to front line treatment (Mycrophenolate & predinsoline - ave dose 20mg). Experienced quite severe diarrhoea after 2 days. Resolved after 5 weeks after taking loperamide, which is no longer required. Also experienced increased fatigue and maybe slightly more cramping (was already getting some cramps which is common for cGVHD). Immunoglobin levels have dropped will require an infusion. Some early signs that skin symptoms ie scleroderma might be reducing. However too early to tell effectiveness, suspect will be another 30-60 days before start to see if going to have impact"

• patri...
• Taken for 2 to 5 years
• April 29, 2023

For Non-Hodgkin's Lymphoma "I developed afib, high blood pressure, dizziness, tiredness, and slightly blurred eyesight. I can only take 1/4 dose as I had an allergic reaction to the full dose. Appears to have slowed the progression of the lymphoma. I depend on Pan Foundation or Johnson and Johnson to help with the price of the medication as I also have infusions every 8 weeks at $963."

• rcp
• Taken for 2 to 5 years
• July 15, 2024

For Chronic Lymphocytic Leukemia "I took it when I was first diagnosed with CLL in 2014. It was the third medication I tried, and it worked very well for me 10 years ago. I was in remission from 2018 till 2023 when my CLL became active again. I tried various new meds that did not work well. Therefore, I asked my doctor to try Imbruvica again. I took it for 4 months, and it stabilized me. Then, I started having neuropathy all over my body, especially my feet and legs. It hurt to walk on my feet, and my legs felt very painful and heavy. My doctor took me off it again in May 2024. Then I began night sweats and felt very tired all the time. He put me back on it, and I broke out in boils. So I stopped taking it as of July 2024. I guess it no longer will work well for me. But in the beginning, it saved my life!"

• Ray
• Taken for 1 to 6 months
• February 22, 2024

For Chronic Lymphocytic Leukemia "Thus far I have done well on Imbruvica. My swollen lymph nodes have been reduced by almost 100%. I am on week 5 and am in the early stages of taking the medication. I have had one mouth sore which cleared up and has not returned. I am fighting a bad chest cough. I see my doctor tomorrow."

• John
• Taken for 2 to 5 years
• September 22, 2023

"For the most part, I've had an excellent response to Imbruvica, with very little side effects. 2 months ago, the 560 mg hard tablet was discontinued. So they changed it to 4 capsules adding up to 560. Since I started taking it, I began having muscle pain and dry eyes in the morning. I'm wondering if it's getting into my bloodstream quicker as a capsule and that is why I'm having the side effects."

• Del
• Taken for 5 to 10 years
• June 23, 2023

For Chronic Lymphocytic Leukemia "On Imbruvica for almost 7 Years. I had to do 2 cycles of RCHOP first as Imbruvica was a second-line treatment. It was very effective at reducing my tumor load and keeping it away with 420 mg a day. I had side effects that were managed for most of the time. The neuropathy, diarrhea, heart palpitations, and lung damage were the most persistent. Fifteen months of bleeding from the lungs was the reason for stopping Imbruvica."

• James
• Taken for 1 to 2 years
• October 16, 2023

"I’m currently going on 19 months with Imbruvica. I take 240 mg once a day. Side effects include all listed. Chemo infusions didn’t work. I was diagnosed with stage four cancer. Liver, spleen, lymph nodes, blood riddled with cancer. First year of Imbruvica reduced signs of cancer all the way to no signs of cancer for 3 months. Then cancer showed itself again in spleen and just a few lymph nodes. Very tired, but with the help of coffee, I can risk going out and doing yard work, shopping, and day trips with family. It was prescribed as a cancer maintenance drug and has improved my way of life versus the year of chemotherapy infusions. I take risks with my family by going outside and enjoying life. Risks such as COVID. But Imbruvica has given some of my life back. I have severe diarrhea daily, brain fog, short-term memory loss, dizziness, high glucose levels, and high blood pressure."

• JjR
• Taken for 2 to 5 years
• September 24, 2023

For Waldenström Macroglobulinemia "I'm very pleased with the drug, but it would be prohibitive if I were on Medicare Part D. I'm not positive if my side effects of pain, fatigue, and diarrhea are caused by this or other health issues..."

• Jinjari
• Taken for 6 months to 1 year
• May 13, 2023

For Chronic Lymphocytic Leukemia "I was diagnosed with CLL in 2013. Treated with Rituxan and Bendamustine. Went into remission but CLL returned in 2022. The oncologist prescribed Imbruvica 420 mg daily. My WBC level is now in the normal range. I suffer a great deal from rash and fatigue since my hemoglobin level and red blood cell count are below the normal range."

• rspre...
• April 17, 2016

For Chronic Lymphocytic Leukemia "My husband took 3 Imbruvica before bedtime and died from sudden cardiac arrest the next morning."

• Genicon
• Taken for 1 to 6 months
• March 25, 2017

For Chronic Lymphocytic Leukemia "Shrunk lymph glands in back of neck first week of taking 3 capsules a day second week swollen glands in armpit are gone minor side effects ."

• Poor...
• July 7, 2017

For Chronic Lymphocytic Leukemia "My husband took 3 Imbruvica before bedtime and died the next day from Sudden Cardiac Arrest"

• Nicole
• January 24, 2017

For Chronic Lymphocytic Leukemia "My 78 year old mother was taking this and in her third month she had vomiting one day back and neck pain for 3 days, then passed away in her sleep, Didn't get a chance to lower the dose."

• Eddie...
• October 27, 2016

For Chronic Lymphocytic Leukemia "Medication has effectively arrested my father's CLL. From 140,000 WBC to 5,000 within two months."