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Imbruvica and Swelling: What Users Say

Swelling: mentioned by 3 users (4.5%)

Based on user experiences from 66 Imbruvica reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

diarrhea 13.6%
fatigue 7.6%
heart palpitations 7.6%
high blood pressure 6.1%
back pain 4.5%
mouth sores 4.5%
nerve pain 4.5%
shortness of breath 4.5%
swelling 4.5%
tiredness 4.5%

Reviews for Imbruvica

  • Anonymous
  • Taken for 1 to 6 months
  • February 2, 2021

For Chronic Lymphocytic Leukemia "After 76 days on Imbruvica (420 mg), my prostate gland was swollen to the point where urination was almost impossible and my colon was blocked. Also, there was swelling felt in my lungs and heart. At times after taking the tablet, I could feel my heart beating against my sternum. The day after I stopped taking the drug, the swelling subsided. I no apparent problems existed on the first two lots of the drug (56 days), I attribute the probable cause to a contaminated lot. After three weeks, my bodily functions seemed to be back to normal. On the follow-up PET scan, no improvement was seen on lymph nodes."

1 / 10
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  • May...
  • Taken for 1 to 2 years
  • April 1, 2025

For Chronic Lymphocytic Leukemia "I was diagnosed with CLL in May 2007, after not feeling well for nearly a year. I went on the sit & wait program. In March 2016, I started my 2nd round of Bendamustine & Rituximab, but was only able to get through 5 rounds. It was clear I wouldn't make it through a 3rd round. February 13, 2022, another trip to the ER, this time for upper chest pain. Coming out of CT, I officially had a heart attack. Doctors inserted 1 stent for a 99% blockage. I thought the pain was from all the swelling in my lymph nodes. My lymph nodes were always the first indicator. This time, the lymph nodes were much larger, egg to large orange. I was trying to hang on till my appointment at the end of February. Two weeks later, at my regular oncology appointment, my oncologist put me on the Imbruvica 420 mg. The Imbruvica was working great! Mid-July 2024, I got through the first of 7 excruciatingly painful granulomas in my mouth. In February 2025, 3 days shy of 2 years, I was told the Imbruvica was the cause. Stopped."

9 / 10
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  • Luk...
  • Taken for 1 to 2 years
  • October 18, 2024

For Chronic Lymphocytic Leukemia "Mild swelling of lower legs at sock line. Purpura with both arms and hands. Mild fatigue. A greater need to rest at times."

9 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.