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Synvisc-One for Osteoarthritis User Reviews (Page 3)

Synvisc-One has an average rating of 6.0 out of 10 from a total of 149 reviews for the treatment of Osteoarthritis. 53% of reviewers reported a positive experience, while 37% reported a negative experience.

Reviews for Synvisc-One

  • mla
  • November 17, 2010

"I have had problems with my knees for few years, sometimes had to use a cane and then others just hurt when I bend down or go upstairs. Osteoarthritis. I took a Synvisc-One shot today and it did not hurt at all. The doctor numbed the area up before inserting the needle. I am hoping it works as well as I've heard it does."

8 / 10
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54 Report
  • Nan...
  • Taken for 2 to 5 years
  • September 28, 2016

"Been receiving Synvisc injections approximately every 6 months for last 3+ years. They help tremendously. There is always a little soreness and swelling of the knee for about a week after injection but then I get 6 months of pain free activity. That's a pretty good trade-off if you ask me."

8 / 10
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35 Report
  • ADINM...
  • March 8, 2017

"I was told I had osteoarthritis and surgery is not an option on my knee due to my age. I had the cortisone shot in August. It did nothing. Therefore, I had the Synvics-one in March. Oh my god, there ought to be law that ALL doctors should be frank with their patients, who are in severe pain and seek relief. Low and behold, I had the shot which was somewhat painful, but bearable. The first night I was in agony...could not sleep for the pain. It has been a week, and severe stiffness has set in. A friend recommend Blue emu for the pain, and Tylenol. The Blue Emu helps, but the pain (which is as worst as last week) is beginning to subside during the day. At night...just horrible, I awake ever two to three hours with pain! Never!!!"

2 / 10
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32 Report
  • Anima...
  • Taken for less than 1 month
  • July 2, 2019

"Just to placate some fears after reading these reviews I'm glad I didn't read them BEFORE my injection yesterday. It absolutely did not hurt at all, just a little uncomfortable/weird sensation as it went through the fibres into the joint . My Dr used the ultrasound before /during /after. Today - 12 hours later - feels 'full' and a little swollen but definitely no pain."

10 / 10
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24 Report
  • Trifi...
  • Taken for 2 to 5 years
  • May 7, 2017

"1st injection= mild swelling then relief. Injection 2 = intense swelling and pain. Synovitis. Had to get a steroid shot. Injection 3= they felt maybe the 2nd injection was in the wrong place and wanted to try again I did. Worse swelling and pain. It is not a suck it up buttercup thing. I am an ironman and have had surgeries. This is abnormal and swelling to the degree of not being able to bend my knee to 90 degrees. Nor straighten. It is painful and tight. Bad reaction not good and not normal. Now I will be at the Doc Monday 72 hrs post injection b/c I am so swollen I can hardly function. He will draw fluid off and give me a steroid injection. This is awful anyway - too common."

1 / 10
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31 Report

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  • MsCltb
  • Taken for 1 to 6 months
  • October 25, 2016

"Knee surgery in March for(I was told)severe Arthritis and two Meniscus tears. The recovery and therapy was awful! My doctor kept giving me Cortisone shots, then he suggested the Synvisc, I finished the Synvisc treatments in July and I STILL have horrrible pain daily! I can't sleep through the night without the pain, unable to stand on my own without holding on to something, and every visit to a store, I look for a basket, just to have something to hold on to. The surgery was a FAIL and all the doctor will say is "you had extensive arthritis, I had to do a lot of work once I got inside of your knee". I am no longer able to straighten my knee out, I can't walk straight which has now thrown my back out of whack! It didn't work!!!!!!!!"

1 / 10
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32 Report
  • Granjan
  • Taken for 1 to 6 months
  • August 27, 2016

"I had the Synvisc-One shot in early May, hoping to be able to dance at my Granddaughter's wedding. I had been walking 2 miles a day, five times a week before I had the shot. Within 72 hours, I was in horrific pain. I sent my husband out to get a walker. 3 weeks later, I wore a knee brace to the wedding, with a tens unit beneath it to mask the pain. When I called the doctor, he prescribed pain medication. I didn't get it filled. I will not get hooked on pain meds. I have a friend I taught with get hooked on pain meds, and it wasn't pretty. Anyway, it is now the end of August, and I still have pain in my knees just sitting in a chair or lying in bed. Wished I had read these reviews BEFORE having the shot!!!!!!!"

1 / 10
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32 Report
  • McDon...
  • Taken for less than 1 month
  • January 1, 2017

"A very pleasant experience, some strange sensations but they were expected. Got the injection December 21, 2016 @ my Ortho's office. Very happy. Used a recumbent bike today at the gym the first time in 6 months without my unloader brace."

10 / 10
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30 Report
  • Dray
  • August 12, 2016

"Omg!!.. im 25 yrs old and 2 months post knee surgery. I continued to have pain due to arthritis in my knee my Dr gave me the synvisc-1 shot and im now 3 days post my shot(8-9-16) i feel sooo much better and can walk sooo much better. I was nervous after reading reviews but i have one of the best Drs in the nation here in LA so i trusted him.. Everyone's body is different and will receive medications differently so i try not to go off of reviews. I cant wait until a few more weeks from now to see how much better i am."

8 / 10
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30 Report
  • tresv...
  • September 26, 2016

"For years I have been in so much pain in my knees and legs that I can hardly walk and spend most of my time sitting on the couch. My doctor used a numbing spray and the shots weren't painful. However by the time I went to bed both knees were hurting so much I had trouble sleeping. My right knee was bone on bone and hurt the most. Now both knees hurt just to sit, my bones, muscles and tendons hurt; I can't straighten my legs. I have to have help to stand up from a sitting position. Walking is agony, so I'm still sitting on the couch but now I'm in constant pain. There is no relief. My legs hurt at night while I'm sleeping. I am also so tired I can hardly stay awake and I am extremely nervous and shakey. Getting out of bed is a nightmare."

1 / 10
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29 Report
  • Anonymous
  • January 29, 2017

"Not really sure. Had a cortisone shot first which did nothing. I then tried the synvisc one. I really didn't have much pain from the injection. I still have pain but it's not as bad as it was. It's been about a week and a half since I've gotten it. From what I've read it may take Month to get full relief. Will report back later."

5 / 10
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28 Report
  • Educa...
  • Taken for less than 1 month
  • January 19, 2020

"I had the single-shot Synvisc One injection and the next day the pain in my knee decreased 50-60%. The key is to make sure you have an experienced orthopedic surgeon do the injection. If the gel does not get in the joint not only will it not work put you may have complications. I will continue the shots until I am ready for a partial knee replacement."

9 / 10
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19 Report
  • AmyJo...
  • Taken for less than 1 month
  • April 17, 2017

"Its been 3 weeks since my first Synvisc One injection in both knees, left knee unbearable pain since day of injection. Pain in places I didn't have before. Pain behind my knee and down my leg, can't sleep, walk or barely drive without pain. I am a professional dog walker and this was supposed to help not hurt. Will never get again! (I'm 42, severe bone on bone arthritis in both knees, have had 4 years of cortisone injections every few months, and take anti inflammatory prescription daily, have tried physical therapy 3 times) I guess I will just wait for knee replacements, and put my life on hold until then."

2 / 10
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27 Report
  • I...
  • June 25, 2017

"I received the synvisc one injection 3 months ago, it did not help my pain ,it causes me more pain and suffering. I barely can walk or sleep. The back of my knee after waking up to start my day, I can't bend my knee without extremely pain. A week after injection I had started dragging my leg because the pain is unbearable. How can I have this injection removed from my knee. I can't live with this very very very very bad pain from the synvisc one injection. the back and front of my knee is agony."

1 / 10
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26 Report
  • Crick...
  • January 5, 2017

"The first time I had a synvisc shot it worked really well with no side effects. The second time I had a shot in both knees and was in a pain, had cramping in my calves and was pretty miserable for about 2 weeks. Now I have popping in my knees as if the fluid got underneath the knee cap or around that area so every time I walk my knees pop and it drives me crazy. I never had this before I got my last shots, so now not only do I have osteoarthritis due to loss of cartilage I now have another complication with every step. I don't believe I will have another shot, and I wish there was some sort of compensation for this."

5 / 10
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27 Report
  • count...
  • Taken for 1 to 6 months
  • June 14, 2018

"I received 1 shot in my right knee about 2 months ago. I wasn't really in much pain before the shot. I had torn meniscus surgery in the beginning of February and was told this shot would help my arthritis. I have pain in both my knees now, my lower back is in pain, I actually feel worse than I did before the shot. Right knee is swollen a bit and went back to ortho doc who said I have a little fluid build up and to keep taking ibuprofen and if not cleared up in a month he will remove fluid. The only explanation I have is these side effects came from the shot and has not helped me one bit. I wonder if anyone else has these side effects."

1 / 10
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23 Report
  • Paul
  • Taken for 5 to 10 years
  • August 9, 2018

"I have been getting the synvisc one shots for years. The first time I had the 4 shots. After about a month I was doing great.. it lasted about 2 years. Then my next shot lasted about a year. I went to every 6 months with the shots and now I am back to one each year. This medicine is about the best.. it works for me. Thanks to my Doctor and this medicine I am able to keep working and living a normal life."

10 / 10
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22 Report
  • ander...
  • Taken for 2 to 5 years
  • October 1, 2016

"I have had about 4 rounds of both knees with synvisc one. I have cortisone shots done at same time. My Dr. Is great. He sprays a cooling spray first then numbs one side. Does the same to other side. He then injects cortisone and synvisc one with just one needle. Doesn't hurt really. I always ask for the cooling spray! Lol!! I guess everyone at this office asks for the cooling spray."

10 / 10
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27 Report
  • Busy...
  • Taken for less than 1 month
  • June 3, 2017

"I have had one problem since I was 10. Patella dislocations. I am 43 and had a partial knee replacement already. They knew that had not had any surgeries and recieved the SYNVISC shot. The worst pain ever. Someone had to hold my leg. I could barely stand and limped in horrible pain. My leg has a big bruise and knot where the shot was administered and the pain had been the same. Praying the pain subsides but I don't have months to wait for relief.I don't think I'll be getting another. The pain had me crying on the bus ride home and I have a high pain tolerance."

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25 Report
  • tucso...
  • Taken for 6 months to 1 year
  • December 10, 2016

"Originally I had SynviscOne injection 4/2016, & although it took about 6+ wks for my knees to feel full benefit, I was pain free about 4-5 months. It was great!! (Not everyone experiences the same benefit for the same amount of time, I was told.) I started getting knee pain pretty badly again late Aug & by mid-Sept. I couldn't take the pain so I got steroid injections in both knees. My insur only allows 2 SynviscOne injections/yr. By the end of Oct. the steroid injections had worn off so I got another SynviscOne injection each knee. It's now 6+ weeks later (Dec. 10) & haven't had much relief to speak of. I'm hopeful in next 10 days or so I'll feel more relief, but honestly it's the best med I've had for my knees."

8 / 10
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26 Report
  • Anonymous
  • June 24, 2017

"I'm not entirely sure which Synvisc injection I just received in both knees, perhaps Synvisc-One as the physician said it could provide pain relief for up to 6 months... I was, periodically, taking Ibuprofen when my knee pain flared up. Anyway, immediately after he injected both knees they felt much better. I thought, maybe, there was some type of Novocaine combined with the injection, but I think the pain relief was most likely just the Synvisc. It's now been almost 48 hours since the injections and I would say my pain reduced dramatically and immediately. I hope it does last for up to 6 months. Your "mileage" may vary, but I hope it works as well for you as it seems to be doing for me. -Nat-"

9 / 10
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24 Report
  • JDM...
  • March 7, 2017

"I received the Synvisc-One injection in early February in both knees. The injection was extremely painful for one knee. It's a month later, I'm still in pain especially at bedtime. Lots of pain/stiffness in my calves and behind my knees. Not sure if I would receive another injection. Can surgery be worse?"

5 / 10
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25 Report
  • Shark
  • Taken for less than 1 month
  • October 25, 2019

"After surgery to repair a tear 3 years later I started to have so much pain. I tried cortisone but did not last. This time I tried the synvisc injection. I was still in a lot of pain until 3 weeks after and it finally kicked in. Now I can finally take my dogs out walking again. No pain at all from the injection it just took some time to start working but worth it."

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17 Report
  • Texas...
  • Taken for less than 1 month
  • August 28, 2018

"55 year old male with arthritic knee. Had one Synvisc one injection July 30th 2018 (Lot number 8rslo11). I was in hospital with infection 2 days later with 3 arthroscopic surgeries to clean out infection. I contracted staph aureus bacteria in blood from injection. I can't walk, I have horrible pain, swelling in thighs, myocitis (muscle inflammation) due to infection. In hospital 20 days. May not be able to have knee replacement in future due to this infection."

1 / 10
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20 Report
  • Anonymous
  • December 4, 2016

"Acute pain and swelling 6 hrs after the injection , unable to walk, difficult to sleep. Can't bend my knee and in absolute agony. Day 5 and my entire life is on hold as it very difficult to move, wish I would never have had the shot- dangerous!!"

1 / 10
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24 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.