Synvisc-One User Reviews & Ratings

• Car...
• July 9, 2019

For Osteoarthritis "I had two prior series of Synvisc-One injections and had some relief. I get a lidocaine shot before each injection to help with pain. This third series has been awful. I have been in agony and have not been able to walk. My left leg calf muscles felt like they were being ripped apart. I was literally in tears daily. I did tell the medical staff of my pain. Third injection was almost two weeks ago and I am still in agony much of the time. Only when I have a full dose of prescription and OTC pain meds, plus lidocaine and other topical applications, in my system do I get relief. And I have to be very careful as to how I move, so as to not jar the leg and start the pain. I have been worse off than I ever was before."

• Fis...
• Taken for 1 to 6 months
• June 10, 2019

For Osteoarthritis "I had a Synvisc-One shot on 4-16-2019 in my right knee. This isn’t the first time, but it will be the last time. Today is 6-10-2019, and I still can’t bend it and limp terribly. I just want to cry. My quality of life has gone downhill since I got this last shot. I called the orthopedic doctor who gave me the shot, and I was seen last week, and he was very short with me and said, 'What did you expect? You are bone on bone. You need a complete knee replacement.' I asked for a sonogram or MRI to see if the medication had done something since I have had these shots before and they worked wonderfully. He said, 'Do you want pain meds?' I said, 'No, I want my old knee back.' I ended with a prescription for steroids again. He never offered either test, and I have private insurance. Lot # from injection: 8RSL056. Maybe it’s time for a second opinion!!! If anyone has anything that they have done to make their knee feel better, please share."

• Jak...
• Taken for 2 to 5 years
• May 2, 2020

For Osteoarthritis "I have mild to moderate osteoarthritis in my right knee from an ACL reconstruction in 2000 and meniscectomy in 2016 to clean up meniscal tears. I have been using Synvisc-One for over 2 years and it has been very effective. It takes me from having a stiff, painful knee to a nearly fully functional joint that I can train and do fairly high-impact sports on. It takes a week or two for it to kick in after an injection. Knee feels stiff and achy at first, but it eases up and within a month, you forget you ever had OA. With the single injection, you are adding an extra 6 ml to the 6 ml already in your knee joint capsule. No wonder it feels full at first. Rest and give it a week or so to blend in. I am 56 and surf nearly every day. Synvisc-One is the miracle solution that keeps my knee pain-free and functional. I highly recommend it."

• ibe...
• Taken for less than 1 month
• July 3, 2012

For Osteoarthritis "I had a knee injury over 10 years ago and was told that later on, I would have Osteoarthritis. Well, that time is here along with bone spurs on the front & back of my knee. Most times I would just live with the pain but at times when it was most unbearable, I would be taking Advil sometimes every other day. When my brother told me he had this injection after an ACL injury and how great it was, I decided to give it a try since my insurance covered it - okay then. I won't lie, the initial injection was painful only because I hate needles and it is not a fast injection because of the fluid being so thick, you can almost feel it going in and around your kneecap, but I will tell you this is the best thing I ever did. No pain at all, going on 3 weeks."

• Suz...
• Taken for 1 to 2 years
• February 21, 2020

For Osteoarthritis "I've been having Synvisc injections every 6 to 7 months for the past 2 years. Sometimes it's a rough couple of days with pain, swelling, and trouble walking, as I have it done in both knees. But once that's past, I am almost pain-free. I hope to push off a knee replacement for a few more years. I'll continue to get injections as they have made a significant improvement in the quality of life for me."

• Jas...
• Taken for 2 to 5 years
• January 12, 2017

For Osteoarthritis "Having lost a quarter-shaped size of cartilage in my right knee, so bone on bone in that one, and in the left knee, advanced osteoarthritis which hurts more than the right, I know about pain. Synvisc is the best! I take 3 shots over 3 weeks (2ml per injection), and it lasts anywhere from 3-5 months. The lasting relief is that I don't get pain from walking or sudden nerve pains during that duration. Everyone is different, but I just get the shots done, no numbing—that's just silly because it's only a needle, for God's sake. Yes, I sometimes get swelling after shots, but reading some claims about 'ruining my life' and 'pain' is really foreign to me. I really like Synvisc, it greatly improves my quality of life. My advice is to 'suck it up, buttercup,' and get the shots."

• Dum...
• Taken for 1 to 6 months
• August 26, 2020

For Osteoarthritis "The orthopedist recommended Synvisc-One for O/A I have in my right knee. I also have patellofemoral osteochondritis. I read many reviews here and decided to have it done X-ray guided vs. just by hand touch to make sure the injection is precise. The radiologist put my knee in a certain position and went through the side, interior side of the knee, so the injection itself was successful and didn't hurt much like others wrote. The knee felt swollen for two weeks with some pain, but after that swelling went away, my old pain came back, the pain under the patella. Today is three months and a half since the injection, and I see no improvement. In conclusion, it didn't help me at all."

• map...
• January 27, 2015

For Osteoarthritis "Excess fluid was aspirated from my knee prior to Synvisc-One injection. My doctor informed me that numbing was not recommended. Aspiration and injection were not very painful at all - just the initial 'pinch.' Swelling was minimal but pain lasted almost a week. 10 days into it, knee is feeling much better. I would do this again."

• rep...
• Taken for 1 to 6 months
• April 27, 2016

For Osteoarthritis "I got this shot on March 17, 2016. It was a preventative measure because my knee is bone on bone, and I would get a cortisone shot every 6 months. 24 hours after the shot, my knee swelled up, and the pain was incredible, I couldn't walk. Three weeks later, after having my knee drained and injected with medicine, I had emergency surgery to flush out the Synvisc. I've been out of work now for 6 weeks, and with going to therapy, I am starting to walk a little better. I hope to return to work in 2 weeks. I had arthroscopic surgery 10 years ago on my other knee, and the day after surgery I was much better than I am 6 weeks later after a preventive shot. Be careful, I think they are hiding all the bad reactions to Synvisc."

• Mar...
• Taken for 6 months to 1 year
• May 6, 2020

For Osteoarthritis "Synvisc One definitely helped a lot for my meniscus tears and osteoporosis. Initially, I was a huge skeptic b/c nothing had helped me. I know that there are mixed reviews & risks. I’ve been an avid runner my entire life. I’ve had 2 meniscus knee surgeries. After the 2nd surgery, I didn’t experience relief. I couldn’t run more than a mile without pain (I’m only 25 years old!). I tried PT, etc., didn’t help. After having Synvisc One, most of the days are now good, and I can now run 5+ miles with minimal pain. It’s amazing. The downside is that I did need another injection after 7 months (but my insurance covers it). I don’t know if I’ll end up needing another. Even with the risks (educate yourselves!), I’m grateful I found something that works for my knee, even if it’s not a guarantee for the future. See a doctor who knows what they are doing, an orthopedic or regenerative medicine doctor. I have found seeing a good doctor is very helpful, especially if you have an adverse reaction, etc."

• Sag...
• Taken for less than 1 month
• June 11, 2019

For Osteoarthritis "This was a terrible experience for me. I had the Synvisc injection, and the next day I was super anxious and weepy. This anxiety lasted 7 days. I am normally none of those things. Over the next 2 weeks, my knee was painful, stiff, and I had to use crutches to walk. The injection did not work, and I will not have another Synvisc injection again."

• Mar...
• June 25, 2015

For Osteoarthritis "I was so nervous about getting this shot - and believe me, it was a piece of cake! It was slightly uncomfortable for about 2-3 seconds, but no screaming pain. After a few days I did notice a reduction in pain. I am now about 4 weeks out from the shot and my knee feels wonderful! This shot has been totally worth it for me. I will get another one when needed with no hesitation."

• chr...
• Taken for 1 to 6 months
• November 15, 2015

For Osteoarthritis "Going on 8 weeks after a Synvisc-One injection and the constant pain is now 10 times WORSE than before. My quality of life is horrible due to pain caused by the shot. I have osteoarthritis in the knee, nothing like the kind of pain I am in now. READ ALL THE REVIEWS BEFORE YOU GET THIS DONE"

• Air...
• December 16, 2011

For Osteoarthritis "I had arthroscopic surgery on both knees for meniscal tears from overuse during my time in the military. After choosing the injections versus cortisones or steroid shots, I've had excellent results. I'm 45 and still run 4 miles every other day without any pain. The injections were not painful and took only minutes in the doctor's office. I finished two series and now ready for my third. I give it an excellent rating."

• Grm...
• Taken for less than 1 month
• March 19, 2016

For Osteoarthritis "Had shot. Shot was nothing, but 48 hrs. later, I can barely stand the pain. Elevating, ice, ibuprofen, but boy oh boy, it hurts BAD. Gave birth to 3 children, one being breech, and swear this pain is worse. I am hoping to be better soon. With this experience, think I will not repeat this adventure. Do not think a knee replacement could be any worse than what I am going through right now."

• Joh...
• Taken for 6 months to 1 year
• January 20, 2015

For Osteoarthritis "Instead of giving me pain relief, it did the opposite. I went from moderate pain to severe pain. It has been 6 weeks, and my condition is worse than before the injection. I'm hoping it wears off soon. When the PA gave me the injection, some fluid came out of my knee."

• Nar...
• Taken for less than 1 month
• June 4, 2019

For Osteoarthritis "I have had bone-on-bone knees for many years and cannot have replacements since I have too many back problems to go through rehab. My knees have been in constant pain for at least 10 years, and narcotic pain meds do little to help. I went for Synvisc One shot in each knee 6 days ago, and the pain is so unbearable all I can do is lie in bed and cry. I am doing ice, but no help. It feels like a knife stabbing my left knee joint, and that’s bad enough, but my right leg from thigh to calf feels like the muscle is being ripped apart. I have had 2 major back surgeries and have rods in my lower back and have never had pain like this. Before, the pain would keep me in bed with ice about 3 to 4 days, but this time I hurt worse every day. Please be aware these injections work well most of the time, but things can go horribly wrong for no rhyme or reason."

• Rob...
• October 18, 2014

For Osteoarthritis "I had a Synvisc-One shot about 7 months ago in my right knee. The injection was not painful at all - just uncomfortable as the thick fluid goes into the knee. I had pain relief for 6 full months. After this experience, I decided to get 2 shots - one in each knee. I had the shots done yesterday, and the pain from the shots was excruciating. The experience was nothing like the first time. I felt like I was going to pass out and as if I had been 'sucker punched' in the gut. I couldn't get off the exam table for 20 minutes and could barely get in my car to drive home. I was in such pain and discomfort I went to bed and slept for 12 hours. Today, I still have discomfort and aching."

• Col...
• Taken for less than 1 month
• March 5, 2016

For Osteoarthritis "Was treated on 3/5/2016. The injection of Synvisc-One was painless, and I felt immediate relief in my knee. Now, just hours later, I notice a greater range of motion for my leg and almost no pain in the knee joint."

• Day...
• Taken for 6 months to 1 year
• December 26, 2014

For Osteoarthritis "I've had both the cortisone shots and the Synvisc-One. I believe they were equally painful, the Synvisc maybe slightly more, as the fluid seems to be quite a bit thicker so there was noticeably more pressure. However, it's been well over 6 months, and I haven't had any pain. I've recommended it for my father and would recommend it if the normal cortisone shots don't seem to work any longer."

• hig...
• Taken for less than 1 month
• July 8, 2015

For Osteoarthritis "This is day 2 after my first Synvisc One shot. The shot wasn't bad, only uncomfortable during the last 3 seconds. I walked out and had a little tightness as the gel was settling in. Day 2 I'm walking around with absolutely no issues and with a 90% reduction in pain. Day 2 far exceeded all my expectations. I am completely pleased and satisfied with Synvisc One. I hope it lasts more than 6 months."

• Qua...
• December 25, 2015

For Osteoarthritis "This was, without a doubt, one of the most painful experiences I have encountered in my 65 years. I had it last January. The shot itself was not bad, but immediately after the shot, the pain around the knee was excruciating. I pretty much lived with pain twice as bad as before I had the shot for the next eight or ten weeks. Staying off of it, icing it, and painkillers were the only help. Eventually, the pain slowed down, but I would recommend that people look carefully and study the possible side effects before doing it. I had a partial knee replacement in July (six months ago) and the results are spectacular. I am walking, doing water aerobics, and extremely active without any pain."

• sac...
• Taken for 2 to 5 years
• December 15, 2013

For Osteoarthritis "I have taken the Synvisc-One shot in both of my knees. It really does work, and I am pain-free for actually six months. The reason I will not take it now is because the last time I was given these shots, it hurt just too bad. Now I am trying to find something else without all the more pain when taken."

• Mar...
• Taken for 6 months to 1 year
• October 6, 2015

For Osteoarthritis "I stopped running marathons, something I really enjoyed. My arthritis has put a stop to any running. Now, I walk 5-6 miles every other day with a pair of weights around my ankles. My arthritis kept me up at night until I started my Synvisc-One injections. I get one in each knee every 6 months; they really make a difference."

• P S...
• August 4, 2010

For Osteoarthritis "I had Synvisc-One injection in January 2010. I'm due for another this month (every six months). I'm an avid 56-year-old tennis player, and my knee has developed severe arthritis through injury (tear and scope) and years of pounding on the court. I haven't been able to play the Singles that I love for three years, as a consequence - and have had to settle for Doubles. No more - this is a miracle drug for me personally. I'm playing singles again and being very active in other ways with no debilitating swelling and pain. It is all good for now. I'll keep taking the shot, and I am so grateful for this drug."