Hydrochlorothiazide and Dry Mouth: What Users Say

• Vkp...
• January 14, 2018

For High Blood Pressure "Bad stuff. Second or third time over the past 3 months trying Hydro. It raised diastolic and heart rate to 90-100! Both were much lower before Hydro. 'Extreme' fatigue, shaky, jittery, dry mouth, dry eyes, gastric pains, hands stiff and weak."

• Bil...
• September 20, 2017

For High Blood Pressure "Terrible drug. I stopped after one week. I had major side effects such as severe nasal congestion, dizziness, headache, dry mouth, and difficulty taking a deep breath. I was very fatigued as well. I will not take this drug ever again."

• But...
• February 5, 2014

For High Blood Pressure "I noticed blood pressure began to stabilize. The side effects were overwhelming. I had a very dry mouth, no appetite. During the day, constant drowsiness and weakness, along with body aches I do not normally experience. I take three other blood pressure medicines."

• Anonymous
• March 7, 2016

For High Blood Pressure "I have been on this medicine for 2 days now. The second day of taking 5 hours after I took it. I had an allergic reaction. Dizzy, dry mouth, heart racing, and felt like I was about to faint. Anxiety panic attacks. Very scary medicine. I advise nobody to take this poison. I'm going back to my Dr. Changing this ASAP."

• Anonymous
• July 22, 2011

For High Blood Pressure "I have used hydrochlorothiazide 12.5 mg for about 2 months now. It has significantly lowered my blood pressure, but I have noticed the arches in my feet hurt, some leg pain, and dry mouth. I also feel I don't have the same ambition. I do not urinate any more frequently than usual. I do think it has affected my sex life though, lowering my sex drive. I take this along with a beta blocker called propranolol 20mg. I will have to get my potassium checked to see how it is doing though."

• Lum...
• Taken for 1 to 6 months
• January 23, 2016

For High Blood Pressure "Works with my lisinopril to lower my high blood pressure. Really bad dry mouth and throat the first week. Also, I pee all the time. My tummy has gotten smaller, and I fit into pants I could never wear."

• son...
• Taken for less than 1 month
• December 4, 2022

For High Blood Pressure "This drug works well in getting rid of water retention. I would give it at least an 8 for that. But the side effects are just horrible for me. So I am rating it much lower at a 1. I've tried to take this medication several times. Every time I end up with a very dry mouth, dizziness, and fatigue. It makes me feel very lousy. It is strange that I used to take this drug for many years as part of a high blood pressure combo such as Valsartan HCTZ. But I can't anymore. I think I am allergic to this medication. I will never take it again."

• Luc...
• August 12, 2017

For High Blood Pressure "I have been on 25 mg once daily of this medication for over 20 years now. I take it with Losartan (beta blocker). I have never experienced any of the side effects (e.g., dry mouth, dizziness, nausea, etc.) that others have reported here. Of course, it's a diuretic, so frequent urination (another side effect others report) is going to occur. But for myself, I've not noticed it, as the only time I experienced frequent urination was due to either a UTI or the massive fibroids that formerly pressed on my bladder; the HZT never contributed to this. So really, I've never had one side effect that I could attribute to this drug at all since I began taking it. In fact, the only warning from the pharmacy is to avoid sunlight or artificial sunlight."

• doe...
• Taken for less than 1 month
• January 6, 2016

For High Blood Pressure "Well, I've been on this medication, 25 mg, for about a week... I started to have side effects about two days in, like extreme dry mouth, like I woke up in the Mojave Desert or something. And I still have the side effect, so I keep a bottle of water handy at night. 2-3 days in, I started to feel the mild cramps in my legs, but it's gone away, so it's temporary, I guess. As for urinating regularly, not sure if it's not high enough or what, because I have not noticed any loss of water, I have been retaining. Really disappointed, so I'll keep taking this med for another two weeks, if I don't notice anything, I'm off it, because it hadn't worked. Oh well, I guess let's see what happens."

• Joe...
• Taken for 6 months to 1 year
• August 2, 2022

For High Blood Pressure "My doctor had me on 1 pill of hydrochlorothiazide 12.5 mg, and after initial cramping, my body was okay after adding more electrolytes. Eventually, I agreed with him to try 2 pills of 25 mg a day, and it went fine for a month or two. Then I had dizziness bouts for a whole day, and I kept taking naps (which I read were signs of dehydration), and my skin and mouth were drier. My vision doubled in blurriness (some from the first pill too), and I got pink eye from the dryness and irritation. I just felt very 'off,' so today I went back to one pill. It does help, but stay on track with your electrolytes, especially if you're doing a low-carb diet AND taking these! On a side note, companies DO put in different ingredients, so if you have a bad reaction, try another company and see if it works better."

• Hel...
• Taken for less than 1 month
• August 8, 2015

For Nephrocalcinosis "I was put on this to lower my chances of getting more kidney stones. I've been on this a few days now and wanted to share my experiences early on. At first, I felt no difference, but the second day I started feeling extreme dry mouth, headache, lower leg cramping, and some frequency of urination, although I drink a lot of water, 1/2 to 3/4 of a gallon a day. But from what I've read here, these are normal side effects as my body adjusts to the medication. I'm going to keep on this until I see the doctor for a recheck in a couple of weeks, and hopefully, these side effects will subside. I'm mainly staying on it too out of fear of a returning kidney stone."

• Mik...
• Taken for less than 1 month
• October 13, 2016

For High Blood Pressure "Started to take this medication, extreme dry mouth and overwhelming fatigue!"

• mch...
• Taken for less than 1 month
• February 22, 2015

For High Blood Pressure "Side effects: extreme dry mouth, nausea."