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Tremfya and Pain: What Users Say

Pain: mentioned by 7 users (7.0%)

Based on user experiences from 100 Tremfya reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

joint pain 10.0%
pain 7.0%
fatigue 6.0%
itching 4.0%
tiredness 4.0%
chills 3.0%
cough 3.0%
headaches 3.0%

Reviews for Tremfya

Commonly mentioned side effects
  • Deb...
  • August 3, 2021

For Plaque Psoriasis "As a type 1 diabetic with 15 years of experience with different types of daily injections, pump sites, etc., I can say the Tremfya auto injector is the worst injector system I have ever encountered. There’s no needle control, and it personally takes a lot of muscle for me to use, and it hurts more when you push down enough to inject because the needle digs in. Overall, very bad design. However, if you dislike seeing needles, then it’s good for you because you never see the needle. By the second injection, I noticed a big difference in my psoriasis. I’ve had severe plaque psoriasis for years, and I just completed my third injection, and currently, there are no noticeable plaques on my body. I’ve been amazed by the results, but I dread each injection. Since being diagnosed with diabetes (at the age of 10), the Tremfya injector is the only needle to ever make me cry, and for that, I’m pretty frustrated. But for the results I’m getting, I’ll absolutely deal with it."

10 / 10
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24 Report
  • Sco...
  • Taken for 1 to 6 months
  • November 29, 2021

For Psoriasis "I feel like just so awful! Very sick with pain, and I think I have inverse psoriasis. Very painful and very itchy. I didn't have any of these issues till I started Tremfya. I have been on the medication for 7 months and went to the Dr, and they said keep taking it, and if my condition doesn't get better, go to your primary. What???? They are the specialists. Don't know what to do, please help."

1 / 10
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20 Report
  • Kri...
  • Taken for 1 to 6 months
  • December 9, 2021

For Psoriatic Arthritis "Last med I took was Otezla before Tremfya, but I chose the wrong insurance plan this past year and eventually couldn't afford Otezla. My rheum prescribed Tremfya then. Back to injections. I've previously taken Humira and presented with PsA while taking it. Does Tremfya work - meh. It's not controlling the PsA or P very well. I mean, I was once unable to dress myself, walk, etc., when the PsA presented, so I'm not back to that point. I wake sore and stiff. My elbows have broken out again. I also have PPP, and I don't have the pustules, but the peeling on my feet is back. I had to have mtx added back on, and this time subQ. So now I'm taking both the 8-week autoinjector Tremfya and a subQ once a week to replace Otezla. I believe the interleukin inhibitors just don't work for me very well, and the PDE4 inhibitors do. After Jan 1 when my good insurance plan kicks in, I'm asking my rheum to put me back on Otezla. Tremfya barely does anything for me."

3 / 10
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16 Report

Frequently asked questions

  • Dx1...
  • Taken for 6 months to 1 year
  • September 14, 2022

For Psoriatic Arthritis "Totally resolved all plaques. Look forward to the shots because I feel like a superhero immediately afterward - but it doesn’t last 8 weeks. After 4 weeks, I’m right back to creaks, cracks, and pains all over, waiting for my next dose."

6 / 10
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5 Report
  • Che...
  • Taken for 6 months to 1 year
  • January 31, 2024

For Plaque Psoriasis "I was covered head to toe with 3 different types of psoriasis. My doctors and I had tried all topicals on the market, UVB light therapy, and methotrexate to no avail. None of these were a long-term solution for myself. They would bring my psoriasis flush to my skin, but I would still be itchy and sore from all the lesions, and the results would only last a few days before it all flared back up. My skin was getting very thin from the topical steroids. With hesitation, I agreed to try biologics. 1 week after my initial loading dose of Tremfya, I noticed a decrease in the severity of my lesions. By the time I was ready for my second loading dose, my psoriasis had vastly cleared; all I really had left by this time was scalp and nail psoriasis. I do find that 8 weeks is almost too long of a wait for me in between doses. By week 6, I start getting spots again, but they are more like tiny little dots that clear up within a week of my next dose. Tremfya is my 1st biologic, and I am impressed with it."

9 / 10
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  • sal...
  • Taken for less than 1 month
  • February 7, 2025

For Psoriasis "I've been using the injection regularly for 2 years. From the first day, I'm completely clear, I no longer have any redness or scabbing. It cleared me 100%. I only missed one dose, and afterwards, when I took it again, I started experiencing pain, but these pains are better for psoriasis."

10 / 10
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  • Dou...
  • Taken for less than 1 month
  • March 10, 2023

For Plaque Psoriasis "I’ve been on another medicine and have given my own shots for years. The first shot of Tremfya hurt so bad, I aborted the shot. I waited the 30 minutes to warm up and had it laying flat. They don’t even provide an alcohol pad to clean the area. Will go back to my former medicine. Those shots are why some people are afraid of needles."

1 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.