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Diflucan and Rash: What Users Say

Rash: mentioned by 6 users (4.2%)

Based on user experiences from 144 Diflucan reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

itching 20.8%
burning 11.1%
dizziness 11.1%
swelling 8.3%
headaches 7.6%
nausea 7.6%
allergic reaction 5.6%
blisters 4.9%
pain 4.9%
rash 4.2%

Reviews for Diflucan

Commonly mentioned side effects
  • Kik...
  • Taken for 2 to 5 years
  • September 7, 2019

For Vaginal Yeast Infection "Have taken sporadically for a yeast infection. Seemed to work, but I broke out in hives. It took me a bit to figure it out because I’d take 1 pill maybe once a year. It didn’t register. Well, now I know! I took 1 pill in March, 1 pill in July, and thought, huh, I wonder if fluconazole. Took 1 pill yesterday and paid attention!!! Yep! Ugh! Hives and allergic reaction not on the list! I get hives, my knuckle swells on 1 finger, and it is painful. It blisters and finally pops and heals on its own. Each time it is worse. Now my lips are swollen, and hives on palms and on skin by thumb. My hands are so dry. NEVER AGAIN WILL I TAKE THIS fluconazole!!"

1 / 10
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32 Report
  • Lin...
  • Taken for less than 1 month
  • February 5, 2018

For Vaginal Yeast Infection "I took Diflucan for a yeast infection on a Friday around 8 PM, at about 10 PM, my lips started to tingle. I went to bed and woke up at 2 AM to find my lips severely swollen with a rash around them. Today is Monday, and my lips are burning, dry, and still swollen. I am now getting sores inside of my mouth from the Diflucan. My yeast infection has cleared up, but the pain I am feeling now is horrific. I will NEVER take this pill again."

2 / 10
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32 Report
  • Bad...
  • Taken for less than 1 month
  • January 19, 2019

For Vaginal Yeast Infection "I have taken Diflucan for yeast infections for years. I always get the infection after having to take antibiotics for a sinus infection (at least 1x/year). I have never had any issues - until now. Twelve hours after taking the Diflucan, I developed 3 hives - two on my face and one on my thumb. I thought maybe it was from something else or stress, so I ignored it. Big mistake. Had to take a second pill this week, and the hives came back in the exact same places, only worse, and have blistered. I also now have blisters inside my mouth and on my lips. They are extremely painful and are healing, but still there after 6 days. I expect scarring. If you have an allergic reaction to this drug, DO NOT take it again. It only gets worse. Now to figure out what I CAN take, as the yeast infection is still there."

1 / 10
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24 Report

Frequently asked questions

  • Ama...
  • November 8, 2015

For Vaginal Yeast Infection "Personally, this drug gives me a fixed drug eruption in the form of a huge, round rash on one of my breasts that is intensively itchy and burns. It feels like a horrible sunburn. Therefore, I am clearly not a fan."

1 / 10
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17 Report
  • Kay...
  • Taken for less than 1 month
  • January 19, 2020

For Vaginal Yeast Infection "After taking one dose of Diflucan, I developed a severe rash, it looked like sunburn on my chest, upper arms, stomach, and back. It was extremely itchy. I’m assuming this is an allergic reaction."

1 / 10
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23 Report
  • Mrs...
  • August 10, 2017

For Vaginal Yeast Infection "Diflucan caused me to break out with a rash on my face and on my arms, neck, and back within two days of starting it. Therefore, I can't honestly rate its effectiveness, so good luck."

1 / 10
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15 Report

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