Diflucan and Nausea: What Users Say

• Nic...
• Taken for less than 1 month
• January 10, 2021

For Vaginal Yeast Infection "I took Diflucan years ago for a yeast infection—got rid of it quickly and efficiently with no side effects! Fast forward to this year. I had a major yeast infection, took Diflucan but this time had multiple weird side effects, including: peeling/swollen lips (with ulcers on the inside), nausea/vomiting, terrible stomach pains and diarrhea, heart palpitations, itchy throat, and increased vaginal and anal irritation. I even developed hemorrhoids for the first time in my life, and I attribute it all to this drug. I think it severely irritated my mucous membranes and then this was only worsened by coupled chronic diarrhea I was having. Be really careful taking this drug... it’s no joke."

• Lil...
• Taken for 1 to 6 months
• January 20, 2017

For Vaginal Yeast Infection "I got one Diflucan pill to take, which I thought at first was a waste of money, but it works GREAT. The discharge and smell changed after 1 day! There were no side effects, no headaches, nausea, pain, etc. Highly recommend!"

• Ano...
• June 14, 2015

For Vaginal Yeast Infection "Took antibiotics and got a yeast infection, went to the Drs, they prescribed Monistat 3. Took it for the 3 days, still was experiencing a lot of itching and burning. Went back to the Drs, she prescribed the one-dose pill. Took it Thursday afternoon, felt nausea, had headaches, and stomach aches (side effects), but helped with the burning pain by the next day. It's now Sunday, and the itching, burning, and pain are back. Going back to the Drs tomorrow for the 3rd time in 2 and a half weeks. So want this to go away. Feeling like I need to get a second opinion."

• Diz...
• Taken for less than 1 month
• September 2, 2019

For Esophageal Candidiasis "I was prescribed Diflucan in the ER for an over-the-moon sore throat I had had for 2 weeks—100 mg for 30 days. The side effects are terrible. It was approximately 2 weeks into the prescription that I began noticing just how truly weak I was. Dizziness is not the best description. More like brain fog + really severe confusion? Being too weak to walk a straight line. My depth perception is severely out of whack. I have fallen on stairs 3 times since starting this awful med. The dry skin started right off the bat. The skin on my face and neck is drying out and sloughing off like dandruff. I have a painful lip crack, moisturizer can’t beat out Diflucan. I’m constipated, I have 7 days to go. I’m going to have to muscle through it. While having vertigo, stumbling around on shaky legs, constipated, with a split lip, and no appetite whatsoever because I’m so nauseous. I do not recommend this medication at all. For me, it’s necessary. Just 7 more days of pure misery."

• Smi...
• May 5, 2011

For Vaginal Yeast Infection "I've taken this as needed over the years without any problem. This time, I had nausea, diarrhea, and dizziness. Our pharmacy gives a printout of all the possible side effects, and it says you can be allergic to it (as most drugs). I guess it just depends on the person on how much you need and how your body will react. It takes more than one dose for me."

• She...
• January 2, 2016

For Vaginal Yeast Infection "I took this pill 2 days ago. I have been sick ever since. I have an awful headache, constantly feel like throwing up, and I'm itchy. Stick to the cream, I have never had a reaction to any medications, so thought this would be fine. Don't risk it!"

• Hor...
• Taken for 1 to 6 months
• October 15, 2015

For Tinea Versicolor "After nine years with a fungal infection on the skin, I was given 100 MG/week for a month. I already took the last pill of the course, and all it has done so far is turn the spots pink and make them slightly bigger, and some itched more often (although one looks like it's starting to disappear)! But the side effects! Oh, the side effects! After the first pill, I felt extremely dizzy, headachy, and nauseous for an hour after bedtime. The next day, I had little appetite that only recovered that evening. The next two times, I took two Rolaids, which helped with the nausea. That left the headache to contend with all day the day after I took the pill. I took two ibuprofen three times to combat the headaches on the last pill. What a joke!"

• Ano...
• Taken for less than 1 month
• April 5, 2025

For Vaginal Yeast Infection "Treated for candida infection, 3 strains, and had lowered immunity. So had Canesten and Diflucan prescribed, 150 mg, fine for 1st day. Next day, severe migraine-like headaches that have lasted every day on and off, bar last 2 days. Off balance, anxiety, and severe nausea for 2 and a half, nearly 3 weeks now. Thrush has cleared up, but couldn't get my GP's surgery to give me an appointment for a couple of weeks. I've had this tablet before, no issues. Never again, feel really ill on it. I'm 65 and normally very active, have had to suspend my gym membership for a month as I feel so unwell. Do not take this drug."

• Anonymous
• Taken for less than 1 month
• January 15, 2015

For Candida Urinary Tract Infection "I am still having problems with a bad taste in my mouth, no appetite, nausea after taking a single dose over a week ago. I suffered a very bad headache for 3 days after the dose. It was miserable."

• Anonymous
• July 23, 2010

For Vaginal Yeast Infection "This was my first yeast infection. The pill worked really well and felt immediate relief. Had vomiting the next day and nausea, which is apparently a rare side effect, but it got the job done."

• kun...
• Taken for less than 1 month
• February 23, 2021

For Vaginal Yeast Infection "Never again. One day after taking Diflucan, I got a splitting headache, severe dizziness, and nausea with vomiting."