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Dronabinol User Reviews & Ratings

Brand names: Marinol, Syndros

Dronabinol has an average rating of 8.3 out of 10 from a total of 61 reviews on Drugs.com. 84% of reviewers reported a positive experience, while 11% reported a negative experience.

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Reviews for Dronabinol

Commonly mentioned side effects
  • swe...
  • Taken for less than 1 month
  • December 2, 2018

Dronabinol for Nausea/Vomiting, Chemotherapy Induced "My father, who has cancer, was wilting away from the pain meds and associated nausea and vomiting. No water either. Mentally, he was in a real bad place. CBD/THC 4:1 oil and Marinol have completely turned him around. He is now only on one prescribed medication versus before three, all of which caused drowsiness. Gaining weight and cracking jokes. Ridiculous how a substance that doesn't cause death by overdose, gives you an appetite, and makes you happy is not available over the counter. Especially when alcohol, which is much worse, is not only legal but glorified. Legalize it. Don't criticize it."

9 / 10
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159 Report
  • Ban...
  • Taken for less than 1 month
  • November 16, 2019

Dronabinol for Anorexia "My father was diagnosed with metastatic melanoma that had spread to his spinal fluid and put pressure on his brain. He was nauseous and unable to eat (and sometimes drink) for weeks before the final diagnosis. Once they figured it out and started heavy steroids, he wasn’t particularly nauseous but he wouldn’t eat. Since there is no effective treatment for the cancer, we were looking for quality of life. Marinol got rid of the last of his queasiness and stimulated his appetite, allowing him to start eating again. Although we’ll lose him soon, at least he has more energy to sit with his friends and occasionally play the piano. It has made a big, positive difference."

9 / 10
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73 Report
  • Mad...
  • June 20, 2016

Dronabinol for Nausea/Vomiting, Chemotherapy Induced "My boyfriend has cancer and was receiving two kinds of chemotherapy. Along with blood clots and a drain in his leg, he was in a lot of pain. When receiving chemo, we would stay in the hospital for three days, and even with the Neulasta shot and all the IV anti-nausea meds, he still was sick. Finally, he was prescribed Marinol, and it changed everything. The day we came home from the hospital after taking it, he was well enough to go Frisbee golfing even with a drain in his leg! He never vomited again, and he actually got kinda chubby! The drug changed his attitude, and I believe it gave him the strength he needed to fight his sarcoma. He's now in remission!"

10 / 10
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106 Report
  • Bar...
  • September 26, 2016

Dronabinol for Nausea/Vomiting, Chemotherapy Induced "After debilitating nausea and vomiting from radiation and chemotherapy, and after trying all the normal drugs like Zofran and some others, I tried Marinol. It was by far the most effective for treating nausea and vomiting of any pharmaceutical. It gives a nice, pleasant buzz as well. The problem for me was the overstimulation of my appetite. I've never felt hunger like this in my entire life. Anyway, people who need this drug could probably use the extra appetite anyway."

8 / 10
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79 Report
  • krb...
  • August 16, 2013

Dronabinol for Nausea/Vomiting, Chemotherapy Induced "Ask your doctor to prescribe Marinol (dronabinol) to cure you of your MAJOR nausea problem. If you are taking large doses of medicines for cancer or HIV/AIDS, then you probably get nauseous a lot! We all know that it's hard to get anything done when you are nauseated all day. This medicine is a game-changer and a lifesaver. I would go as far as to say that this is a miracle. I'm still in shock how well it is helping my nausea since nothing I ever took before helped as much as this medicine!"

10 / 10
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92 Report

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  • Moo...
  • Taken for 1 to 6 months
  • July 28, 2017

Dronabinol for Nausea/Vomiting, Chemotherapy Induced "I am surprised this isn't oncologists' 'go-to' drug. After my first A/C infusion for breast cancer, I had severe nausea and vomiting immediately. The doctor prescribed 25 mg of promethazine orally and rectally (in case I couldn't hold down the pill). All it did was make me sleep for hours, induce a migraine status headache, and cause severe stomach pain/cramping, and I would still wake up vomiting. Then my doctor prescribed Dronabinol 5 mg. It was a miracle drug. The stomach pain, nausea, and vomiting completely stopped. It made me slightly tired in the beginning, but the feeling was more relaxed than tired, therefore I could continue to function normally. It also stimulated my appetite, which is very important for chemotherapy patients."

10 / 10
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66 Report
  • Mic...
  • July 24, 2015

Dronabinol for Anorexia "I have common variable immunodeficiency, which causes anorexia. I found Marinol 5 mg taken a couple of hours before meals makes a huge difference. If I do not want to eat, ulcers, etc., I found it easier with Marinol and have actually gained around 10 lbs in the initial month or two. I would recommend it for any patient with weight loss issues!"

9 / 10
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68 Report
  • Anonymous
  • March 16, 2010

Dronabinol for Nausea/Vomiting, Chemotherapy Induced "My doctor prescribed Marinol after I had adverse reactions to most antiemetics given to me during chemotherapy. Converting from IV to oral cytotoxins, nausea made my quality of life poor. Marinol made such a positive change for me. Taking between 2.5 and 5 mg, there is only about 20 minutes of silliness, which my family welcomes, then relief from vomiting for 6 to 8 hours. It has been a lifesaver for me and for my family."

9 / 10
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87 Report
  • Mik...
  • Taken for 6 months to 1 year
  • July 1, 2018

Dronabinol for Nausea/Vomiting, Chemotherapy Induced "Marinol medication was given to me for extreme nausea due to gastroparesis. It has been a godsend. It loses some efficacy if you overuse it but is very effective for nausea relief when others haven’t helped. I highly recommend this medication."

10 / 10
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45 Report
  • 9IN...
  • August 22, 2009

Dronabinol for Anorexia "I suffer from appetite suppression as a result of medication which I take for narcolepsy (Amphetamine-based). Although the medicine works wonderfully, the only negative side effect that bothers me is appetite suppression. Hence, my introduction to Marinol! I would like to clarify a common myth that Marinol is a form of prescription 'medical marijuana'. My doctor explained it is a synthetic cannabinoid, a distant chemical cousin of marijuana that lacks recreational effects at therapeutic doses. It works by activating the endocannabinoid system of the brain, which regulates appetite. When I first tried it, it started working by the end of the next day!"

10 / 10
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89 Report
  • Anonymous
  • March 19, 2012

Dronabinol for Nausea/Vomiting, Chemotherapy Induced "I have never personally taken this medication. However, my mother recently was prescribed Marinol after other medications provided no relief from chemo-induced nausea. Her first dose took about 3 hours to kick in (which is a long time when you're nauseated), but after that, she's been a brand new person. I'm guessing it takes those first few hours to get fully in your system. She takes it twice a day and has had little to no nausea."

10 / 10
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72 Report
  • mys...
  • April 7, 2015

Dronabinol for Anorexia "Amazing! My stress after my tonsillectomy led me to relapse into anorexia. This medication saved my life, allowing me to enjoy flavors of food and gain 10 needed pounds. Amazing life changer, and my depression is less chronic."

9 / 10
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57 Report
  • Inj...
  • Taken for less than 1 month
  • December 4, 2014

Dronabinol for Anorexia "I am a disabled veteran with a spinal injury. The opioid med was all I knew for my back. I have since been amazed at the pain relieving ability of this medicine. It helps me eat and allows for a more positive day."

10 / 10
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56 Report
  • Gen...
  • Taken for 1 to 6 months
  • July 3, 2012

Dronabinol for Anorexia "I lost my appetite when I was diagnosed with autoimmune hepatitis. I take 5 mg twice a day. My stomach has to be completely empty in order to feel the effects of the pill. Even with a bowl of ice cream or a milkshake in my system, I will not get anything from the pill. You have to time it right because the effects kick in an hour (or later) after taking it. It's hit or miss, but when it hits, it allows me to eat for 3 hours straight."

8 / 10
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61 Report
  • Bea...
  • Taken for 1 to 6 months
  • September 17, 2017

For Post Traumatic Stress Disorder "I have PTSD, 2 double lung transplants, bronchomalacia, gastroparesis, and Nissen fundoplication. A-fib, A-flutter, vertigo, pulmonary artery stent, cardiac arrest, sternal wires, and artificial right hip. Extruded and mangled L4 and L5. Two back surgeries, smashed thoracic vertebrae, and broken toes. Broken ribs, CMV, donor-specific antibodies. Blah blah blah. A lot more to go, but Marinol has been a savior. Keeps me from puking daily, knocks out most of my pain, and does wonders for my anxiety. Screw taking Klonopin, Norco, and Zofran. This covers most of the bases very well."

10 / 10
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41 Report
  • Tyl...
  • Taken for 1 to 6 months
  • August 13, 2014

Dronabinol for Anorexia "I have severe gastroparesis at a very young age as a male. I have exhausted every single option other than surgery, and nothing seemed to be working. My doctor recommended Marinol. At the time, I did not know what the drug consisted of. He told me, and I accepted it over the experimental surgeries they wanted to perform as the only other option. I began taking the medication for increasing my appetite, nausea, vomiting, and the pains associated with gastroparesis. It has worked wonders for me, and it doesn't have the same severe side effects as Phenergan, Reglan, Domperidone, etc."

10 / 10
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49 Report
  • Anonymous
  • May 28, 2009

Dronabinol for Nausea/Vomiting, Chemotherapy Induced "I used Marinol for nausea during cancer therapy. I have to take some narcotics for excessive pain, and Marinol still keeps the nausea down that the narcotics create. It makes my life quite a bit easier."

9 / 10
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67 Report
  • luc...
  • Taken for less than 1 month
  • May 9, 2014

Dronabinol "I've had chronic pancreatitis for about 7 years. I've struggled with nausea and vomiting for so long. Reglan, scopolamine, Phenergan, Zofran-I've been on all of them. Yes, they worked at first, but Marinol is best for me. For the first time in years, I'm not sick! I don't have an appetite like some do, it does make me giddy for an hour or two, but I'm finally not sick at my stomach!"

9 / 10
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43 Report
  • Tya...
  • March 12, 2020

For Post Traumatic Stress Disorder "Since my doctor prescribed me dronabinol, I no longer have nightmares and greatly reduced my anxiety attacks as a result of my PTSD. With absolutely no high, my dose I am taking is 10 mg 3 times a day."

10 / 10
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19 Report
  • mob...
  • Taken for less than 1 month
  • September 3, 2015

For Nausea/Vomiting, Chemotherapy Induced "I have gastroparesis and a pacemaker for it in my stomach. I've been on every nausea medicine, and this is the only one that worked! I felt so relaxed, and my mood went up, and my appetite is better than it was."

7 / 10
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25 Report
  • Ton...
  • Taken for 1 to 6 months
  • September 21, 2018

For Nausea/Vomiting, Chemotherapy Induced "I have advanced small cell lung cancer. I'm currently now up to 104 lbs thanks to dronabinol. I have an increased appetite and overall sense of relaxation with the drug. I think it's wonderful. It does what it says, and I just enjoy the feeling it gives you and relax and EAT! I've gained weight, and it relaxes me. Same high as weed, just takes longer to kick in. I think people are waiting on euphoria because it's made in a lab. Same thing, just give it time. It's pure THC! Chill out, relax, and enjoy!"

9 / 10
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20 Report
  • wha...
  • Taken for 6 months to 1 year
  • March 31, 2019

For Nausea/Vomiting, Chemotherapy Induced "I've been on Marinol for about 2 years for nausea, appetite, pain, and anxiety. I've had 12 surgeries on my stomach and nearby areas. I've lost 50 lbs in the past couple of years, and it would have been a lot worse without Marinol. It works on multiple areas, yet now my insurance won't pay for it after 2 years, and it's $300 a month, so I'm not sure what to do besides the old-fashioned way, but I would rather have the Marinol. Thank you."

8 / 10
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16 Report
  • sky...
  • Taken for 2 to 5 years
  • May 17, 2012

Dronabinol for Nausea/Vomiting, Chemotherapy Induced "I have the 2.5 version. It works well about 90% of the time, while Zofran works about 50% of the time for me. However, I don't like taking even one because of the hangover the next day. Further, it enhances the chronic pain, making the pain worse sometimes. Never know when that will happen."

8 / 10
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35 Report
  • Air...
  • May 23, 2010

For Nausea/Vomiting, Chemotherapy Induced "I was just put on this medicine about 2 weeks ago. So far, it has helped a lot with the nausea and a little bit of the vomiting (so far). It has also helped with my appetite a little, seeing that I can seem to eat only one meal a day. This will be a welcome effect if it keeps working or even starts to work better for that. The biggest hurdle or trouble I had was with the insurance company not wanting to pay for it, I could not afford to pay it either (about ten dollars a pill, the entire 30 pills were almost 300 dollars). So after getting prior authorization denied, I asked my doctor to write a letter to the insurance company stating why she feels I should be on it, it finally went through. So I would recommend this to anyone suffering! Stop suffering."

8 / 10
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29 Report
  • Mik...
  • Taken for 5 to 10 years
  • December 17, 2022

For Post Traumatic Stress Disorder "Suffering from CPTSD, constant nightmares, daytime flashbacks, and treatment-resistant depression, I was prescribed dronabinol 40 mg/day. This drug changed my life completely. If it wasn't for this amazing drug, I would have committed suicide long ago. No more anxiety, no more depression, and I dream about happy unicorns."

10 / 10
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7 Report

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