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Doxepin for Major Depressive Disorder User Reviews

Brand names: Silenor, Adapin

Doxepin has an average rating of 7.2 out of 10 from a total of 4 reviews for the treatment of Major Depressive Disorder. 75% of reviewers reported a positive experience, while 25% reported a negative experience.

Doxepin rating summary

7.2 average rating out of 10

4 ratings from 5 user reviews.

Compare all 57 medications used in the treatment of Major Depressive Disorder.

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  • Mis...
  • Taken for 6 months to 1 year
  • October 24, 2016

"I've taken almost every SSRI and even a few MAOIs. I started taking Doxepin, and wow! I was finally sleeping the whole night through! Since I've been sleeping better, I am up at a normal hour. I am able to do the things that I used to do. I, without a doubt, find Doxepin to be far superior to any of the antidepressants that I've ever been on. Plus, the anxiety I used to get at bedtime, always worrying if I am going to be able to sleep, is gone now. I hope that others have the positive effects that I now have."

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59 Report
  • Par...
  • August 29, 2019

Sinequan (doxepin) "It’s the best antidepressant for major depression. I recommend it highly. I have no side effects. I take 250 mg a day in divided doses - one in the morning, one in the afternoon, and three at night. It took me a year to find it, and I love it. Thank you."

10 / 10
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34 Report
  • Bri...
  • Taken for 6 months to 1 year
  • September 6, 2019

"Did absolutely nothing for my insomnia, depression, or anxiety. Had bad nightmares, gained a heap of weight. Psych told me to stop after 9 months. Not taper off, just stop! My goodness, not a good idea... moody, awake all night, asleep all day, felt sick, was manic for 8 hours straight. Never again. I don't understand why I was not tapered off. Not happy with psych at all."

1 / 10
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10 Report

Frequently asked questions

  • Lan...
  • Taken for less than 1 month
  • March 14, 2019

"I was prescribed doxepin for depression, anxiety, and trouble getting to sleep. I started on 25 mg and still couldn't sleep, so moved up to 50 mg. Was able to sleep amazing and enough to settle thoughts and fall asleep and stay asleep. Only side effects I have noticed are strange dreams and had difficulty, like most people, who don't want to wake up in the morning."

8 / 10
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10 Report
  • Tip...
  • Taken for 6 months to 1 year
  • August 16, 2014

Sinequan (doxepin) "It has greatly improved my mood, and I have been sleeping wonderfully too."

10 / 10
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81 Report
Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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