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Doxepin for Insomnia User Reviews (Page 4)

Brand names: Silenor Adapin

Doxepin has an average rating of 5.7 out of 10 from a total of 288 reviews for the treatment of Insomnia. 48% of reviewers reported a positive experience, while 40% reported a negative experience.

Reviews for Doxepin

  • Anonymous
  • Taken for 6 months to 1 year
  • November 25, 2015

"Had a brain injury, sleep 2 to 3 hours a night. Take Doxepin 10 mg I have found to take the capsule a part dump out about 5 mg of medicine. I can sleep 6 to 7 hours and wake up feeling great. No hangover. Even if I wake up during the night I can go back to sleep. This drug is wonderful if used correctly"

10 / 10
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  • Anonymous
  • October 28, 2010

Silenor (doxepin) "I had been using Ambien for years but gradually developed a tolerance to this medication. I was also frustrated with the frequency of waking during the night. My GP prescripted 6.0 Silenor tablets about two weeks ago and thus far, I am very pleased with the effect on sleep maintenance."

10 / 10
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  • Finally...
  • Taken for less than 1 month
  • June 21, 2017

"After the doctor tried other pills on me for depression, anxiety, PTSD and insomnia with horrible nightmares he decided to try 100mg of Doxepin in the evenings saying it was an older pill not used as much anymore. My body is resistant to medications and requires high doses of meds in order to notice any affects. Its hard for them to knock me out for surgery and keep me knocked out. But so (it's only been about a week) far the Doxepin has been working great at making me sleep. It takes several hours to knock me out but when it does I'm out without waking up every 10 minutes in misery with nightmares and physical pain. I tend to be groggy in the mornings though. I hope my body doesn't grow resistant to it."

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Frequently asked questions

  • Matvei
  • Taken for 1 to 6 months
  • February 22, 2020

"I have sleep maintenance insomnia/early awakenings (no trouble falling asleep in the first place, but a world of hurt trying to stay asleep after 4 or 5 hours). Doxepin worked like a dream for about three months - good (7 hours) sleep, no side effects - then zilch, nothing, back to the bad old days, even if I took ten times the dose. If you have mild/moderate insomnia, this should work for a while, but don't bank on it long term. Cheap too as a generic."

5 / 10
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  • PHick
  • April 21, 2016

Silenor (doxepin) "Been using it for about 5 months and it has been a miracle worker until recently. A few weeks ago started having random sleepless nights. This week has been terrible waking up after 3-4 hours and feeling wide awake. Not sure if my body is getting used to it but I thought I'd check the reviews to see if anyone else has had the same problem. I hope this is a fluke because Silenor really had changed my life and even though it was expensive it was worth being able to function the next day."

8 / 10
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Are you taking this medicine?

  • Cano
  • Taken for 1 to 6 months
  • June 16, 2019

"I’m a 68 yr old female who falls asleep easily but has difficulty staying asleep. Doctor prescribed 10 mg Doxepin which helped with staying asleep all too well. I had trouble waking up at usual time. Insurance won’t pay for lower dosage, so I cut 10 mg capsules, which always results in losing some medicine, but the slightly less than 5 mg works greats do reduces cost too boot. No ill effects at this dosage."

8 / 10
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29 Report
  • GDano
  • May 28, 2018

Silenor (doxepin) "I was prescribed Silenor for insomnia which I battled with for 3 years. I was taking a high dose of Melatonin to sleep but that stopped working when I was going through a stressful period. Took 3 mg of Silenor the first night. Although I slept 5-6 hours , I felt horrible the next day. I felt like crying all day. I increased the dose to 4.5 mg and was able to get 7 hours of sleep but the negative mood became more prominent during the day. I was depressed and miserable. I stuck with it for 2 weeks but my mood was getting worse. I couldn't keep on taking it. I don't know if this is only initial side effects that will go away after a month or so but I personally could not handle the depressive symptoms (major) it gave me so I decided to stop it after 2 weeks only. I felt better immediately even though I am still struggling with sleep... I have to see my doctor and try Trazodone."

2 / 10
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33 Report
  • MS407
  • October 29, 2016

Silenor (doxepin) "Difficulty sleeping through nite I did sleep first night but then most of next day on silenor. 2nd night tossed and turned but slept for about 4 hours. Felt drugged the next day. Took 3rd night slept off and on. Felt horrible next day, tired, weak feeling, headache. Also leaves mouth extremely dry. Not going to take silenor any more."

9 / 10
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  • ValC
  • October 3, 2016

"I've had sleep issues for years and after having multiple sleep studies done as well as nasal surgery to fix deviated septum, I tried a dental sleep appliance and a c-pap machine and nothing worked. I was finally given Doxepin - OMG LIFESAVER...6 drops per night and I am out like a light wake up around 5 hours later but refreshed and not tired. However, if I go off routine, as in different time-zones, late nights, it does take a while to get back on track...I'd be in a mental health institution if I hadn't found this as I was at the end of the rope and couldn't cope anymore being constantly exhausted."

10 / 10
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  • Paited
  • Taken for less than 1 month
  • January 17, 2020

"Started dose of doxepin was 10 mg for insomnia. Slept some but definitely not enough. Moved dose up to 20 mg and I’ve done well thus far with few awakenings. I'm off Xanax after 15 years. Finding anything to help me sleep has been a huge challenge. Try this. Get doxepin generic not the the name brand or you will pay $$$$$"

8 / 10
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  • Thatc...
  • Taken for 1 to 6 months
  • October 5, 2018

"I was put on many different sleep medications before Doxepin and nothing worked for how bad my insomnia is. My doctor had to put me on 30mg of it just to get it to work at all. But once we got the dosage right it works perfectly. Puts me to sleep in 10 to 15 minutes. Other people freak out with my high dosage but, if it works it works. The only downside for me was when I take it I have to sleep for 8 hours or more my body literally will not wake up otherwise. Whenever I did manage to wake myself up before 8 hours I always ended up falling asleep while I was doing something."

8 / 10
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31 Report
  • Needs...
  • Taken for less than 1 month
  • October 1, 2018

Silenor (doxepin) "I tried both the 3mg and the 6 mg to try to sleep and they did nothing for me. I didn’t feel anything and I still had a hard time falling and staying asleep. I didn’t have any side effects but also no sleep. My doctor gave me samples of the medicine to try so I thought I’d give it a hopeful shot but it just didn’t do anything for me."

2 / 10
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  • Mark4...
  • Taken for 1 to 6 months
  • November 22, 2019

"Amazing how varied responses are to this drug doxepin! I take a 50mg capsule before bed and sleep well for 7-8 hours . Have vivid dreams but not nightmares and wake refreshed on a good day but not always. I find it better than elavil."

10 / 10
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  • berry...
  • Taken for 1 to 2 years
  • June 29, 2016

"I've been taking 100mg @ night for insomnia/anxiety for approximately 1 1/2 years! I love it! I take it about 30-45 minutes before bed and BAM I'm out! The only side effects I've noticed is talking in my sleep (nothing major though)!! I would highly recommend this medication for insomnia."

10 / 10
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  • asiss...
  • Taken for 1 to 2 years
  • September 17, 2016

Silenor (doxepin) "I have trouble sleeping from 3 - 6 am. I wake up and cannot go back to sleep creating the daytime symptoms of insomnia (see: http://www.mayoclinic.org/diseases-conditions/insomnia/basics/definition/CON-20024293 ). I rarely have trouble falling asleep. I have been taking LIQUID doxepin for 18+ months (along with a 5 mg time release melatonin) - 30 min before bedtime. The LIQUID has to be especially prescribed by your Dr and approved by your drug company. A 120 ml bottle is $79 - with medicare & drug co approval, my out of pocket (last bought in 6/2016) was $7! Much cheaper than Silenor. I am prescribed 0.6ml/night, but sometimes I take 0.5ml or less, & never over 0.7ml (rarely). Doxepin & melatonin work well to help me sleep from 10p-6a!"

9 / 10
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  • Craig
  • Taken for less than 1 month
  • February 4, 2020

"Took it for insomnia, and I did sleep, woke up several times as usual but I did sleep better. Trouble came the next morning. I should have taken it on a weekend and not on a work day, almost impossible to get up and moving the next morning, hangover all day. Will not be using again"

1 / 10
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  • Dizzy...
  • Taken for less than 1 month
  • March 10, 2017

Silenor (doxepin) "Silenor works very well keeping me asleep longer than usual. I normally wake up 3-4 times a night without it. But I have extreme dizziness and headaches the next day. I think I'll go back on my Lunesta because I have trouble functioning the day after Silenor. It is a great medicine but I'm not sure if it's for me."

8 / 10
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  • Sleep...
  • September 21, 2011

Silenor (doxepin) "OUTSTANDING. It sustains sleep!! But the COST of this medicine is, well, stunning. But I still think this is a near-miraculous medicine. I am menopausal and had a "pattern" of waking at 3:30AM. Horrible. By taking Silenor -- and ONLY Silenor -- I am guaranteed sustained and uninterrupted sleep. THE DOWNSIDE. The cost. I cannot afford Silenor at this time... And it makes me very, very sad."

10 / 10
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51 Report
  • notice
  • Taken for 1 to 6 months
  • February 9, 2020

"I took this for the first time last night, and what an awful night I had, and today well I am just a mess, My dr took me off Xanax as he said it's was the worst meds to take and put me on 10mg Doxepin, I'm not taking it again, will be calling the dr Monday."

1 / 10
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  • KathS
  • Taken for less than 1 month
  • February 17, 2014

"First night on 10mg didn't fall asleep until 5:15 am after 4 am popcorn binge. Woke up about 7:30 am. Same on next 3 nights with middle-of-the night coffee-cake, chocolates and even a couple of frozen dinners. Dr. upped to 20mg. Same result. Hardly any sleep, night snacking, and started eating more during the day. People have commented about rapid weight gain. They're right. I gained 8 lbs. the first week! My weight has been pretty consistent by 2-3 lbs. for years. Going back to Ambien!"

1 / 10
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  • NCAno...
  • December 15, 2011

Silenor (doxepin) "I have been using Ambien for several years and I seem to have built a tolerance so that I am no longer falling asleep nor staying asleep. (Note: I have used both Ambien and Ambien CR). I was on a "local" trip and had forgotten my Ambien, so I asked my Dr if she had samples of anything that would help me sleep. She gave me Silenor samples. While I was extremely happy with the sleep, I did wake up "hungover" and had a hard time getting moving. I also experienced very real hallucinations. Don't know if they will lessen with use, but I am going to ask for a months supply to see if it works out after an adjustment period."

6 / 10
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  • Veron...
  • August 22, 2014

"This medication is the first I've tried for insomnia and it's better than nothing, but there has to be something better. I have problems staying asleep and 80% of the time it helps that, and if I wake up for the bathroom or a snack (okay two snacks), I can fall back asleep quickly. But the weight gain! I had no idea it would cause me to gain so much in a short period. 25 or so pounds in 3 months. I will be looking into Prosom instead and hopefully be able to drop this weight."

6 / 10
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  • Anonymous
  • August 4, 2011

Silenor (doxepin) "I have been taking Silenor 3mg for over 6 months now. I have had zero nights when I have had to get up because of failing to return to sleep. Most nights I get 7 to 8 hours of sleep. The only thing different is having vivid dreams most of the time. Not sure if that means more deep or rem sleep is taking place. Silenor does not put you to sleep but it will let you stay asleep. I highly recommend it for sleep maintenance."

10 / 10
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50 Report
  • Arthur...
  • February 9, 2014

"I was given doxepin 50mg after a very bad experience using Xanax for insomnia. It works fine for my depression, I have a good energy level during the day, but it doesn't do a thing for my insomnia. I feel that if I can solve my insomnia it would go a long way to helping my depression."

2 / 10
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  • bookl...
  • August 7, 2019

Silenor (doxepin) "The first time my Dr gave me Silenor samples, he didn't tell me it specifically helps you "get back to sleep" so it didn't work for me because I didn't take anything with it. A year later, I tried the 6 mg samples again. This time I added 3mg Melatonin (time released) and 1 -25mg Benadryl to help me initially get to sleep. When I woke up to go to the bathroom I COULD GET BACK TO SLEEP!! I take it every night without fail. I don't like having to make sure I've not eaten for 2 1/2 to 3 hours before I take Silenor, but it was worth it to get a good night's sleep and I thank Jesus and my Dr for helping me to find it! I use CVS pharmacy and it was cheaper to get a 3 month supply ($125) from the mail order company than going to the store. This worked REALLY WELL for me for about one and a half years!! Now I am having trouble sleeping even with my 3 pill concoction. I may try going back to Trazadone and Melatonin. We'll see..."

8 / 10
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24 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.