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Doxepin for Insomnia User Reviews (Page 5)

Brand names: Silenor Adapin

Doxepin has an average rating of 5.7 out of 10 from a total of 288 reviews for the treatment of Insomnia. 48% of reviewers reported a positive experience, while 40% reported a negative experience.

Reviews for Doxepin

  • Anonymous
  • December 23, 2010

Silenor (doxepin) "I took Lunesta only for a few days because it gave me unpleasant taste. It was really bad. Then I switched to Ambien. It was better than Lunesta, but there was a residual effect that the medicine made me irritable and anxious next morning. My doctor gave me Silenor. It is better than Ambien CR. I do not feel anxious or irritable next morning and I can sleep 8 hours. The only side effect, though very minor, is that it makes me sluggish a little. But, overall, Silenor is better than Ambien CR. "

9 / 10
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50 Report
  • mskrazy
  • April 17, 2016

"Have been taking doxepin 10mg for sleep for at least 10 years. When I found this, I felt like I might actually manage life. Have problems staying asleep since onset of menopause and doxepin really helps. Since I am overweight my doctor will only prescribe for me to take every other night as he believes it causes weight gain. We disagree on this subject."

9 / 10
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34 Report
  • Boddie
  • Taken for 6 months to 1 year
  • March 3, 2016

"I take about 10 milligrams of Doxaprin about four nights a week. I've been doing this for about 8 months now .I don't have trouble falling asleep I have trouble staying asleep and Doxaprin keeps me asleep. I now sleep like a baby on this 4 nights. I don't really build a tolerance up to it like I did with xanax. I find virtually no side effects other than I don't want to get out of bed in the morning but a cup of coffee solves that. Unless there is some long term side effects I don't know about I can't say anything negative about this substance good luck."

8 / 10
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34 Report

Frequently asked questions

  • Sleepy...
  • Taken for less than 1 month
  • June 27, 2015

"I was having trouble falling asleep. I would lay there for hours. Still even with this drug I can't "fall" asleep and still I lay there for hours. This drug makes my eyes red watery and blurry. The next day after taking this med I am sooo sleepy. I just don't think this is the drug I need."

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36 Report
  • Mae
  • Taken for less than 1 month
  • June 5, 2019

"I’m not sure, but has anyone taken this & passed out so hard that they don’t even remember falling asleep? I’m on 25mg & I fall asleep like quickly, but I do wake up early no matter what time I wake up. I can admit some days I’m tired throughout the day, but I’ve never had a medication work so well for my sleep issues."

7 / 10
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23 Report

Are you taking this medicine?

  • Robin...
  • November 15, 2016

Silenor (doxepin) "I have had severe insomnia for about 3 years. My physician gave me 2 sample packs of 6mg Silenor. I cut them in half to take 3mg as needed. They worked wonderfully and I finally got several good nights of sleep without the groggy feeling in the morning. After the samples were gone, I got my Rx filled and found out my insurance will not cover it. After having been awake for 36 hours straight, out of desperation, I paid an arm and a leg for the Silenor. The first tablet of the Rx worked but that's it. I Increased to taking 6 mg and it still didn't work. Still no sleep. I have given up on Silenor and have gone back to a different insomnia Rx that works sometimes but at least my insurance covers it it only costs me $5."

1 / 10
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31 Report
  • MJano
  • Taken for less than 1 month
  • May 23, 2019

"Was on Quetiapine 100 mg which made me sleep all day and night. Psychiatrist changed my medicine to Doxepin 25 mg and I am on day 3 and have only slept 5 hours total in 3 days. Called his office to advise and his Secretary (non medical person) advised myself that it was going to take time and to continue. I fired him as what Dr allows a Secretary to give Medical advice. Seeing a Neurologist that specializes in sleep disorders tomorrow."

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23 Report
  • BSFMI
  • Taken for 1 to 6 months
  • May 27, 2016

"I have severe sleep problems and now take 50mg of doxepin nightly. I fall asleep and stay asleep. I have tried numerous other meds and most either don't work or work for only a short period of time, this has not been a problem with doxepin."

10 / 10
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32 Report
  • Tonywo
  • Taken for less than 1 month
  • March 24, 2019

Silenor (doxepin) "The vivid nightmares and felt like sleeping all the next day made me not try it a second time. I think it’s possible because I am so sleep deprived if I took on a Friday night I could laze around all weekend and maybe get back to feeling normal."

6 / 10
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23 Report
  • pepper
  • Taken for 1 to 6 months
  • November 29, 2018

"For chronic insomnia, I ran into a anxiety situation of which my diazapam was not effective. I took this and found (with the D) yes it worked for both, yes groggy and lazy the next day, I never get more than 4-5 hrs sleep anyway. Yes have gained weight. Male 56 YO."

5 / 10
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23 Report
  • FastA...
  • Taken for 1 to 6 months
  • November 16, 2019

"I found this medication to be the perfect match for my sleeping issues. I fall asleep faster and stay asleep it's so nice. I've only been taking it for a month and am hopeful it'll last for a long time."

9 / 10
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20 Report
  • Anonymous
  • February 5, 2011

Silenor (doxepin) "I've been on Lunesta for 3 years and would sleep 8 hours exactly every night..Cost went to $125 a month (New Insurance) and then switched to Ambien but only slept 4-5 hours a night. Tried Silenor for the first time last night and slept almost 11 hours."

10 / 10
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43 Report
  • Sarah...
  • Taken for 1 to 6 months
  • September 4, 2016

"Prescribed for nightmares and night terrors due to PTSD. trazadone gave me a horrible body buzz and made me feel like I wasn't in control of my faculties. Worse off, it didn't stop the nightmares, just made it harder to wake from them. Doxepin was prescribed at 25 mg capsule, increasing to 75mg over a period of a month. Stopped the nightmares and night terrors instantly, with no body buzz. In fact, I don't dream at all anymore, and I'm okay with that. Miracle drug. I was becoming desperate and fought sleep as long as I could so I didn't have nightmares. This saved my sanity."

10 / 10
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29 Report
  • Shan...
  • June 23, 2016

Silenor (doxepin) "First night I tried a half. Fell asleep but woke up and was wide awake through the rest of the night. 2 nd night took a full pill feel heart pounding numb fingers can't fall asleep now wide awake. Worse then first night."

1 / 10
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29 Report
  • Benzo...
  • May 18, 2015

"This made me sooooooo tired and drugged feeling I could barely wake up! It was terrible! I hate insomnia but this was ridiculous! This stuff is not a solution! Unless all you do is sleep. So frustrated! Thought this was the one!"

2 / 10
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32 Report
  • Anonymous
  • January 5, 2011

Silenor (doxepin) "Just tried Silenor at the 6 mg dose and it works great for me. I didn't think there was an alternative for treatment of insomnia until my doctor told me. I have been on the others and did not do me any good. Those would include Ambien and Lunesta. I just want to sleep and now finally I can."

10 / 10
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41 Report
  • Anonymous
  • December 29, 2010

Silenor (doxepin) "I took Silenor 6 mg and slept like a rock but had a terrible time getting going the next morning. Although I drank coffee I still felt groggy and in a light daze well past noon. Going to try cutting it in half to 3 mg and see if it works without the groggyness."

3 / 10
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  • boyzmom
  • Taken for less than 1 month
  • February 17, 2020

"I tried 5 mg dose of doxepin by dividing the contents of a 10 mg. capsule. No help for my insomnia. Then tried the whole 10 mg. Still no help for my insomnia (didn't make me sleepy at all; I was up all night), but I felt awful the next day with a dry mouth. Strange, because I remember this putting me to sleep back when I used it for depression decades ago (even when I had weaned down to just 10 mg aday). Wonder if the generic is the same potency and quality now? Back to doxylamine (OTC generic Unisom), which works well, but is pricey."

1 / 10
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17 Report
  • Anonymous
  • November 15, 2011

Silenor (doxepin) "I was given samples of Silenor, and I've been taking it for about two weeks. My problem is not only that I can't sleep for more than 2 hours straight, but it also takes around 3 hours to fall asleep. Anyway, I noticed that I was getting a lot of terrible nightmares right away with the Silenor. As someone who hardly ever even remembers her dreams, the nightmares were quite obviously related to the medicine. Also, the Silenor didn't help me fall asleep/stay asleep at all. My doctor switched me to Ambien, and I'm trying that for the first time tonight. Most of you had a bad experience with Ambien and are loving the Silenor, so I'm not sure how this will work out."

2 / 10
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37 Report
  • Mushy
  • Taken for 1 to 6 months
  • July 12, 2018

"Been taking Doxepin 10 mg every night for two months. It helps me sleep but that’s all I want to do now! It’s near impossible to get up in the morning and I’m fatigued and irritable all day. I used to be very active but now everything is a chore and I’ve put on weight. I would recommend this only if nothing else worked for you."

5 / 10
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21 Report
  • Daisy...
  • Taken for less than 1 month
  • September 30, 2016

Silenor (doxepin) "I have had chronic insomnia for 5 years. I struggle to fall asleep, and once I'm asleep, I never sleep longer than 45 minutes - 1 hour without waking up. I take Ambien when I can afford it, so I have to limit myself to only a few times a week. I was given a sample pack of Silenor about a year ago, but the online reviews made me not want to try it. I was desperate last night, so I tried one 3mg. My heart raced and it did not make me sleepy. I took another half 3mg. and finally dozed off about an hour later. The amazing thing is that even though I never felt sleepy from it like I do with Ambien, I actually slept for 3 straight hours on the Silenor. I do have a tiny headache today, so I don't know if I will take it again."

7 / 10
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  • Lumbe...
  • Taken for less than 1 month
  • September 3, 2016

"Doxepin is the fourth medication that I have been prescribed for my insomnia. Prior to Doxepin, I had taken melatonin (as many insomniacs begin with), Trazodone, and Seroquel. I do not remember any noteworthy effects from the first two, but I was amazed with Seroquel. It worked like a charm once I fell asleep. However, it often took me far too long to fall asleep and I felt extremely groggy, sometimes for hours, when I woke up. Still, I was very satisfied, having finally found something that brought me some much needed rest. When I switched doctor's, though, I was switched to Doxepin. I have only taken it for a short time, but I cannot praise it highly enough. It takes effect far more quickly and has less grogginess than Seroquel (for me)."

8 / 10
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  • Anonymous
  • July 6, 2011

Silenor (doxepin) "My sister had a stroke 5 yrs ago and has not been able to sleep since. I read about Silenor on the internet and got her doctor to prescribe it. She has now had her first good nights sleep in almost the last 5 yrs. "

10 / 10
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36 Report
  • aunti...
  • Taken for less than 1 month
  • September 15, 2015

"I was prescribed 10mg pills for insomnia; I fall asleep readily, but can't stay asleep for more than 2 hours at a time. That's partially due to having dry mouth; drink something, have to go to the bathroom, wake up with a dry mouth, drink something, go to bathroom - vicious cycle. I'm awake for about 15 minutes after each episode. I took doxepin for 4 days out of 9. I started having very vivid dreams, to the point that I did not know what was actually real the next day. I also started feeling "who am I?", "where am I?","what am I doing here? - in other words, very disoriented. I had walked to a neighbor's house to get paperwork for the Civic Assn. I truly had no clue what the lists were, or what they were for. I glad I made it back home."

2 / 10
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  • Doxepin
  • Taken for 1 to 2 years
  • October 28, 2023

"Best sleep medication I've used for insomnia. However, I wish my prescriber had informed me about the weight gain. I never would have used it. I went from 125 lbs to 155 lbs in 18 months. I couldn't figure out what was causing this, along with severe bloating. So, I'm now weaning myself off because you can't just stop taking it, or you'll go through withdrawals. It also makes it harder, especially for women, to lose the weight. Ugh! Everyone is different, but I wouldn't recommend this drug!"

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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.