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Benadryl for Nausea/Vomiting User Reviews

Rating: 7.0

Benadryl has an average rating of 7.0 out of 10 from a total of 21 reviews for the treatment of nausea/vomiting. 57% of reviewers reported a positive experience, while 24% reported a negative experience.

10
38%
9
14%
8
5%
7
10%
6
0%
5
10%
4
0%
3
5%
2
5%
1
14%

Reviews for Benadryl

Commonly mentioned side effects
  • Anonymous
  • June 15, 2012

"I have emetophobia, that is, a pervasive fear of vomiting. I do not know if this affects vomiting, but if I feel nauseous, Benadryl works wonders. My stomach settles right down and my anxiety lowers just enough for me to deal with it without the use of benzodiazepines."

7 / 10
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194 Report
  • A b...
  • Taken for less than 1 month
  • December 20, 2015

"I got a severe back injury about 2 years ago. Couldn't function, pain was so bad. So my doctor started putting me on codeine, then Vicodin, then tramadol, and then so on, but they all gave me hours of vomiting, gut-wrenching cramps, and sweating. Read about Benadryl being used to prevent this side effect. I took 3 25 mg tablets. I know that is one over recommended dose, but I was desperate. 35 minutes later, I was sitting with my kids and not by the trash can for the first time in a while. I can't believe I didn't figure this out sooner, especially with a biotech degree."

10 / 10
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107 Report
  • Sha...
  • December 20, 2022

"Benadryl has been incredibly effective for nausea and vomiting, in my experience. There are times when I'm so sick that I literally can't eat, but give me some Benadryl and within an hour or two, I feel much better."

9 / 10
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28 Report

Frequently asked questions

  • Mar...
  • June 5, 2016

"I had a couple of surgeries on my jaw where I could not open it fully for an extended period of time. I am already semi-allergic to pain meds/anesthesia (excessive vomiting and nausea), so I was terrified to take my painkillers after surgery. The nurse/doctor recommended taking a couple of Benadryl tablets (25 mg) before the pain meds, and it worked wonders! The only side effect is drowsiness."

10 / 10
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52 Report
  • Sim...
  • Taken for less than 1 month
  • September 14, 2017

"ER gave me 25 mg diphenhydramine IV for nausea. The only effect was delirium and a brief medication nap. I felt woozy and poisoned for at least two hours afterward. It may work for others, but it certainly didn't help me."

3 / 10
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29 Report

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  • Pat...
  • Taken for 6 months to 1 year
  • October 2, 2024

"It's a miracle worker with benzodiazepines, take 50 mg with Xanax, etc. If you're like me with a decent tolerance or don't seem to get what you wanted from it. Benadryl amps the effect and takes away more anxiety. Love it!"

10 / 10
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0 Report
  • Ros...
  • Taken for less than 1 month
  • September 3, 2022

"I used to take this med when I was younger. I had no side effects. Now, as an adult, a child's dose gives me nightmares and hallucinations. I do have Hashimoto's and take levothyroxine, not sure if that's the reason in the mix. Then again, my friend who is older than me and takes levo for Hashimoto's has no side effects from Benadryl."

5 / 10
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0 Report

More FAQ

  • net...
  • Taken for less than 1 month
  • October 29, 2022

"Took Benadryl when I was out of town and did not have my generic brand Equate with me. I had done this twice, and both times, the Benadryl made me sick with diarrhea and nausea. I will always stick with the Equate for hay fever, as I never feel sick from it."

1 / 10
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2 Report
  • Mmw...
  • December 29, 2015

"I get severe migraines and was given this in the hospital instead of traditional nausea meds. It works well and I now use it at home and actually works better than Zofran or Phenergan."

10 / 10
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84 Report
  • wor...
  • Taken for 10 years or more
  • October 2, 2015

"I use it for nausea. It works wonders for me."

10 / 10
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85 Report
  • cd1...
  • Taken for 1 to 6 months
  • November 30, 2014

"Great for nausea. However, does cause sleepiness."

9 / 10
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89 Report
  • And...
  • November 24, 2015

"I have Cyclic Vomiting Syndrome and take Benadryl every day. It helps take the edge off. There are fewer side effects than other anti-nausea medications and is safest for the body."

9 / 10
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73 Report
  • mai...
  • Taken for 6 months to 1 year
  • May 8, 2018

"The nurses at my cancer center, where I get my chemo treatment, give me Benadryl before my chemo medicine, and it works wonders, but it puts me to sleep once every week."

10 / 10
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42 Report
  • Anonymous
  • September 2, 2017

"I take Methotrexate weekly, 25 mg, and have found that taking Benadryl at a dose of 12 and 24 hours after my weekly dose helps reduce the nausea."

8 / 10
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23 Report
  • joy...
  • Taken for 2 to 5 years
  • November 6, 2022

"Benadryl works better than Zofran for me, but it knocks me out. But when you're so sick with nausea, you don't care. I take 1 full tab."

7 / 10
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7 Report
  • Ano...
  • Taken for 6 months to 1 year
  • January 24, 2021

"Take it for my migraines or cluster headaches to help with nausea. Works amazing for me."

10 / 10
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10 Report
  • Dia...
  • Taken for less than 1 month
  • September 12, 2020

"Benadryl seems to help with light nausea from hormones and/or motion sickness."

10 / 10
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10 Report
  • Alm...
  • Taken for less than 1 month
  • February 29, 2020

"Made me very anxious and didn't help my nausea at all."

1 / 10
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9 Report
  • Anonymous
  • April 12, 2012

"Didn't seem to work very well for me."

2 / 10
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15 Report
  • Wil...
  • Taken for less than 1 month
  • March 22, 2021

"I used it originally for food allergies but ended up puking (expected, to be honest). Not long after, I took another to wave off the extra symptoms like nausea. All it did was induce vomiting again."

5 / 10
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2 Report
  • Amy...
  • Taken for less than 1 month
  • August 7, 2018

"I took a single pill of Benadryl, and it made me vomit, nauseous, diarrhea, dry throat, and gave me a stuffy nose. I wouldn't give this to my worst enemy."

1 / 10
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28 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.

Learn more about Nausea/Vomiting

Symptoms and treatments

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