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Diphenhydramine User Reviews & Ratings (Page 5)

Brand names: Benadryl, Banophen, Benadryl Allergy, ZzzQuil, Diphen, Unisom SleepGels, Sominex, Benadryl Children's Allergy, Calm-Aid, Diphenydramine Quick Melt, Nytol, Unisom SleepMelts, Diphenhist, Diphendryl, Buckley's Bedtime, Hydramine Cough Syrup, Diphedryl, DPH, Diphenyl, Beldin, Hydramine, Hydramine Compound, Allermax, Dytuss, Dormin, Snooze Fast, Sominex Maximum Strength Caplet, Unisom SleepMinis, Unisom Liquid, ConRx Allergy, Dicopanol, Hyrexin, Bydramine, Diphen AF, Diphen Cough, Aler-Dryl, Allergia-C, Benahist-10, Benahist-50, Benoject-50, Diphenadryl, Genahist, Aller-G-Time, Sleep Tab II, Nytol QuickCaps, Trux-adryl, Valu-Dryl, Altaryl, Belix, Vicks QlearQuil Nighttime Allergy Relief, Silphen Cough, Diphenylin, Nytol Caplet, Compoz Nighttime Sleep Aid Sleepinal Help I Can't Sleep Twilite Banaril Aler-Tab Siladryl Allergy Sleep-ettes D Diphenmax Ben-Tann Dytan Vanamine PD Pharbedryl Histaprin Z-Sleep Aurodryl Children's Allergy Simply Sleep Complete Allergy Relief Miles Nervine Scot-Tussin Allergy Sleepwell 2-nite …show all brand names

Diphenhydramine has an average rating of 5.5 out of 10 from a total of 541 reviews on Drugs.com. 43% of reviewers reported a positive experience, while 40% reported a negative experience.

Reviews for Diphenhydramine

Commonly mentioned side effects
  • Tom...
  • Taken for less than 1 month
  • February 24, 2019

Diphenhydramine for Insomnia "They do help me sleep, but I feel really terrible in the morning. Very groggy and very short-tempered. Have had to throw the pack out, as I feel so awful in the mornings. I've not noticed this to this degree of morning grogginess with other sleeping tablets. Horrible stuff!"

3 / 10
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17 Report
  • Nic...
  • September 8, 2015

Diphenhydramine for Insomnia "Funnily enough, after taking this, I feel it is easier to fall asleep during the day than at night. After an unintentional 12 hours of sleep (just couldn't wake myself up), I was awake for a few hours, then was too drowsy and fell asleep again. I really feel these tablets work better during the day than at night. :("

5 / 10
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22 Report
  • Nut...
  • Taken for less than 1 month
  • June 4, 2020

Diphenhydramine for Insomnia "I took half a Sominex last night to try to get a deep sleep. I slept better, but I am a wreck today. Bad headache, nausea, and extreme muscle fatigue and weakness. Wondered whether it was the Sominex, and reading some of the reviews, it looks like it is. Even had to nap this afternoon and still feel awful. Binned it."

4 / 10
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13 Report

Frequently asked questions

  • Dee...
  • March 4, 2014

For Insomnia "I have been taking half of a pill for years, but just recently have felt that it has not been as effective, so I increased to a whole pill (25 mg) and it works great with no sluggishness the next morning. Also, ever since I have been taking these every night for sleep, I have noticed that I have fewer sinus infections (I have allergies), so it serves two purposes for me."

10 / 10
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20 Report
  • bro...
  • Taken for less than 1 month
  • January 25, 2022

Diphenhydramine for Insomnia "I have had trouble getting to sleep after I stopped taking oxycodone that I had been taking for broken ribs. ZzzQuil actually had the opposite effect than what it promised. Was jumpy and couldn't get to sleep for hours. I gave it three days to work, and each was the same. Rubbish!"

1 / 10
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9 Report

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  • Loa...
  • December 24, 2018

Diphenhydramine for Insomnia "I think this is a brilliant drug to take when you want to break a run of bad nights. I tried it as I couldn't take Night Nurse (which I used to take) as it has contraindications with another tablet that I take at the moment. I only need half a tablet, like other people, I can get up in the night if I have to and go back to sleep. I wake up feeling refreshed. Thank you, Sominex."

9 / 10
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14 Report
  • Anonymous
  • Taken for less than 1 month
  • October 2, 2020

Diphenhydramine for Insomnia "I went on a trip away, and the change of environment, i.e., sleeping in a different room and change of bed, made it very difficult for me to sleep. I had 3 hours of sleep for 2 nights running, so I decided I needed to do something about it. I tried Nytol, and it made me sleep an average of 8 hours, so it worked really well. The only downside is the 'fuzzy' head feeling the next day and feeling spaced out. However, for a short-term solution when you need to get back into a good sleep rhythm, I would highly recommend it. Not for taking long-term though."

8 / 10
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10 Report

More FAQ

  • Anonymous
  • Taken for less than 1 month
  • January 11, 2021

Diphenhydramine for Insomnia "Been suffering with insomnia after losing my dad recently and this whole pandemic. I have to say Nytol has worked really well for me. No side effects, takes about 20-40 mins to start to relax and drift off. Once asleep, I’ve slept through unless interrupted by the cat or kids (they’re teenagers). I feel like I’m getting decent quality deep sleep, which I haven’t for a while, so I’m pleased with that. It’s given me the energy to train the next day, which we all know is the best therapy."

9 / 10
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9 Report
  • Mig...
  • Taken for 5 to 10 years
  • May 19, 2018

For Nausea/Vomiting "Diphenhydramine has saved my life. I have a severe migraine disorder that comes with extreme nausea and sudden vomiting. I now take liquid diphenhydramine, sold as children's med, for nausea and vomiting. I tried pills, and they are not fast-acting enough, and the dose is too high, so it makes me very sleepy. The smaller liquid dose knocks my nausea out almost immediately and only makes me mildly sleepy. I carry this med on hand at all times and take it as needed when I feel the first sign of nausea. If I feel like a full migraine is coming on, I'll take the complete adult dose. The reduction in nausea, in addition to the powerful sleepiness, can really help me avoid more expensive or risky migraine abortive medications. I've taken this medication for years, and the only chronic side effect that I've noticed is dryness/dehydration, but I compensate for that with added water and fish oil. Thank you, scientists, for diphenhydramine!!"

10 / 10
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14 Report
  • pet...
  • Taken for less than 1 month
  • October 15, 2019

Diphenhydramine for Insomnia "I was using the liquid form, and it was fine, working for me, but yesterday I took 2 of these pills. I slept for 5 hours, and now I have a terrible headache. I took 2 painkillers, but it doesn't help at all. I can't sit or work or concentrate. Terrible pill, will not take it again."

1 / 10
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12 Report
  • Zzz...
  • Taken for less than 1 month
  • September 26, 2022

Diphenhydramine for Insomnia "Desperately in need of sleep and decided to take ZzzQuil tablets. This product DOES NOT WORK! I tossed and turned, horribly restless, could not get any sleep! Heart pounding, pulse at high speed! Vicks must remove this product, like now!"

1 / 10
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7 Report
  • Qui...
  • June 21, 2017

Diphenhydramine for Insomnia "At first, I thought I found the perfect drug, I slept finally! But the side effects are pretty much there. (Dizzy, blurred vision, strange emotions, anxiety), and after every use, they are getting stronger."

6 / 10
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15 Report
  • Jen...
  • Taken for 6 months to 1 year
  • May 12, 2012

Diphenhydramine for Allergic Reactions "I use this medicine for weather allergies and allergies to medications when I need it. It does help greatly, but does not last long, and my burning sensation comes back into my body and the hives start to show. However, a lot of people say that this medicine makes them feel sedated. I have the complete opposite, I take 1 before bed, and I will not sleep."

8 / 10
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21 Report
  • Pef...
  • Taken for less than 1 month
  • March 25, 2020

Diphenhydramine for Insomnia "Nytol did not help my insomnia. A waste of money. I don't know how the company dares to make the claims it does in its adverts in the UK. The problem with the product has a warning that it may make you feel drowsy - if only it did."

1 / 10
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15 Report
  • Bab...
  • Taken for less than 1 month
  • December 27, 2017

For Nausea/Vomiting "Was told by pediatrician to give to 4-year-old for nausea and vomiting for a virus. I tried Pepto-Bismol but vomited it back up within 10 minutes. Ondansetron was prescribed to the entire sick family. My son and I tried our ondansetron and still felt nauseated. After 4 hours, it was clear we needed to try something else. The Benadryl is definitely helping."

10 / 10
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14 Report
  • Bra...
  • Taken for less than 1 month
  • September 1, 2020

Diphenhydramine for Insomnia "For years, I’ve suffered from insomnia. I could fall asleep, but I would often wake hours earlier than I was supposed to and would wind up exhausted all day. Lately, I’ve had trouble falling asleep in addition to staying asleep. I’ve tried melatonin and sleepy tea with no success, but I was desperate and gave ZzzQuil a try. I typically get very sleepy 30-60 minutes after taking it and can sleep for 8 hours without feeling “hungover” in the morning. My body is actually a little stiff when I get up because I haven’t even moved all night."

10 / 10
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10 Report
  • Mot...
  • Taken for 2 to 5 years
  • August 3, 2017

Diphenhydramine for Insomnia "Certainly helps me to sleep. But first time I slept for about 12 hours, which meant that I slept badly the following night. I now take 3/4 of the tablet for a solid 8 hours. I suggest trying 1/2 or 3/4 your first time. The first half hour or so on waking leaves me groggy, then I'm fine. Also seems to help me sleep really well the following night. I use only occasionally."

9 / 10
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13 Report
  • Sco...
  • August 23, 2020

Diphenhydramine for Insomnia "A complete waste of money. I have had recent sleep problems, so thought this would be a solution. It had no effect whatsoever, apart from causing a headache. This made the dire warnings I got from the pharmacist when I bought it about long-term usage and dependency completely laughable. I considered returning the garbage to them and demanding my money back."

1 / 10
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12 Report
  • Sim...
  • Taken for less than 1 month
  • September 14, 2017

Diphenhydramine for Nausea/Vomiting "ER gave me 25 mg diphenhydramine IV for nausea. The only effect was delirium and a brief medication nap. I felt woozy and poisoned for at least two hours afterward. It may work for others, but it certainly didn't help me."

3 / 10
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29 Report
  • bra...
  • Taken for 1 to 6 months
  • March 6, 2024

Diphenhydramine "I have tried hydroxyzine in the past for panic and anxiety, and it did not work for me. In fact, it always made my anxiety worse. Benadryl, on the other hand, works amazingly well. Now, it's as needed and should not be taken every day, but as a temporary panic medication, it worked very well for me."

10 / 10
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3 Report
  • Sle...
  • Taken for less than 1 month
  • January 13, 2023

Diphenhydramine for Insomnia "I took this for sleeplessness caused by anxiety. Personally, I found that Nytol knocked me out and kept me asleep, which was great because I needed the sleep, but the next morning, each time I would wake up and lose my balance, I felt faint and lethargic the whole next day after taking them, alongside aches and pains all along my body and heart palpitations."

4 / 10
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5 Report
  • Mel...
  • Taken for 5 to 10 years
  • July 24, 2019

For Nausea/Vomiting "Uhhhhhh.... Wow..... All I have to say is that I have had extreme nausea all night... I tried Dramamine. Didn’t work. I remembered that diphenhydramine can also be used for nausea relief. So I took a liquid gel (50 mg), and it’s been maybe 10-15 minutes, and I already feel better. Thanks again, diphenhydramine!!"

10 / 10
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13 Report
  • Fir...
  • Taken for less than 1 month
  • January 17, 2021

Diphenhydramine for Insomnia "I decided to try these after a period of either not being able to sleep or waking up and not getting back to sleep. Having read quite scary side effects of prescription sleeping tablets, I thought I'd try these first. So... I did drift off to sleep around 30-40 mins after taking a tablet. I woke up in the night to go to the bathroom but did get back to sleep much faster than usual. The downside was feeling spaced out (a bit like a hangover) until lunchtime the next day! I'd not take them if I had an early start or important meeting. I'd recommend trying them but don't expect anything amazing. If your sleep issues are acute due to a trauma, etc., then I'd suggest these wouldn't work sufficiently."

6 / 10
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8 Report
  • Ann...
  • June 12, 2020

Diphenhydramine for Insomnia "I have insomnia for the past several months, and a friend told me to try ZzzQuil. I took it at 10:00 p.m. and went to bed 30 minutes later, but still can't sleep the entire night. I was so disappointed that it did not work at all. What a waste of money."

1 / 10
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9 Report
  • Ano...
  • August 6, 2008

Diphenhydramine for Insomnia "This stuff works ridiculously well. The first time I took it, I woke up the next morning and I was instantly wide awake and full of energy, it's like nothing I've ever had before. Absolutely no drowsiness carrying on to the next day."

10 / 10
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25 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.