Diphenhydramine User Reviews & Ratings (Page 3)
Brand names: Benadryl, Banophen, Benadryl Allergy, ZzzQuil, Diphen, Benadryl Children's Allergy, Sleep Tablets, Diphenhist, Calm-Aid, Unisom SleepGels, Dormin, Nytol, Simply Sleep, Dytuss, Dicopanol, Buckley's Bedtime, DPH, Valu-Dryl, Diphenyl, Altaryl, Sominex, Help I Can't Sleep, Siladryl Allergy, Snooze Fast, Sominex Maximum Strength Caplet, Unisom SleepMinis, Unisom Liquid, ConRx Allergy, Hyrexin, Hydramine Cough Syrup, Bydramine, Diphedryl, Diphen AF, Diphen Cough, Aler-Dryl, Allergia-C, Benahist-10, Benahist-50, Benoject-50, Diphenadryl, Genahist, Aller-G-Time, Sleep Tab II, Nytol QuickCaps, Trux-adryl, Beldin, Belix, Vicks QlearQuil Nighttime Allergy Relief, Hydramine, Silphen Cough, Diphenylin, Hydramine Compound, Nytol Caplet, Compoz Nighttime Sleep Aid, Sleepinal, Allermax, Diphendryl Twilite Banaril Aler-Tab Sleep-ettes D Diphenydramine Quick Melt Diphenmax Ben-Tann Dytan Vanamine PD Pharbedryl Histaprin Z-Sleep Aurodryl Children's Allergy Unisom SleepMelts Complete Allergy Relief Miles Nervine Scot-Tussin Allergy Sleepwell 2-nite …show all brand names
Diphenhydramine has an average rating of 5.5 out of 10 from a total of 548 reviews on Drugs.com. 43% of reviewers reported a positive experience, while 40% reported a negative experience.
Reviews for Diphenhydramine
- Yes...
- March 26, 2013
Diphenhydramine for Insomnia "I have taken Sominex for a few days now and still wake up after 2-3 hours of sleep and can't get back to sleep again. I am so tired. Yet I can fall asleep in the chair really easily in the day. I was hoping Sominex would work, but so far it really hasn't."
- LAG...
- May 27, 2017
Diphenhydramine for Insomnia "I usually work a 10 hr shift in the afternoon, but my boss has changed my Saturday shift to 5 am-1 pm. We live on a farm and have 3 outside dogs that like to bark at night. The first morning shift, I only got 2 hrs sleep because of our dogs. I purchased ZzzQuil to get some help falling asleep the night before my morning shifts. I took the recommended dose (2 pills) at 8 pm. I went to bed at 8:30. I didn't feel any effect from the medication until almost 10:30!! And then I woke up again at 12:30 am! I do not recommend ZzzQuil if you want to fall asleep quickly and stay asleep."
Frequently asked questions
- What are the strongest sleeping pills?
- What is the max dose of diphenhydramine for adults?
- How Fast Does Benadryl Work? Onset Time and Duration
- Does diphenhydramine raise blood pressure?
- Hid...
- Taken for less than 1 month
- March 30, 2023
Diphenhydramine for Insomnia "Couldn’t believe the effect these things had! Rather than falling asleep, I was irritated, restless, and slept almost zero minutes all night. Never again. Save your money, not only does this product not help you sleep, but achieves the exact opposite!"
- Ann...
- Taken for 1 to 6 months
- June 21, 2022
Diphenhydramine for Insomnia "Works great for me and my family. Tired and able to sleep within 30 minutes. I wake up feeling rested. For all those people saying it doesn't work, it just doesn't work for them. I'm sure there isn't a product that exists that works for everyone."
- use...
- October 28, 2014
Diphenhydramine for Allergic Reactions "I was given Benadryl at the hospital for an allergic reaction. It instantly shot my heart rate up to 217 bpm, and instantly my mouth got dry. I couldn't swallow, my chest felt hot, like an elephant was sitting on it, and I got really cold. It put me into shock, my body wouldn't stop shaking, I could breathe. It was so scary, I thought I was dead. Thanks to the doctor's quick response, he saved me, but it almost killed me."
- Rob...
- Taken for less than 1 month
- March 3, 2023
Diphenhydramine for Insomnia "On two separate nights, took 50 mg: slept for 3-4 hours, then wide awake at 3 am, and mood felt low, not a nice feeling. Tried again on another night and had one of the most horrific nightmares I’ve ever had and haven’t had a nightmare for years before now, rarely ever get them. Now don’t want to sleep as don’t want another nightmare, and mood feels horrible. Won’t take these again."
More FAQ
- Does Mucinex help with Covid?
- Can diphenhydramine be used as a sleep aid?
- Does Benadryl help with or cause anxiety?
- Diphenhydramine Hydrochloride vs Citrate: What's the difference?
- Gi-...
- Taken for 1 to 6 months
- June 26, 2015
Diphenhydramine for Insomnia "Works for me in the same manner all the above have stated. Be aware, though, it is intended for occasional use, not nightly use. Its active ingredient is basically Benadryl, the same as in many allergy meds. If you check ingredient labels rather than going by the brand name, you may be able to find a bargain."
- Luc...
- October 3, 2018
Diphenhydramine for Insomnia "Diphenhydramine is a fantastic sleep aid, but you need to follow the dosage very, very carefully. I've struggled with insomnia since basically puberty, and a few years back I began taking ZzzQuil daily. I slowly grew a tolerance to it and increased my dosage eventually to 100 mg. One night I was so fed up with tossing and turning, I took another 100 mg (I was 19, OK?). An hour later I was watching the walls ripple like the surface of a pond, little black dots crawling up the walls here and there, and full-blown auditory hallucinations. (I.e., I heard orchestra music coming from the bathroom vent fan amidst its hum). I felt like my body was made of lead and was horribly lethargic. Still, after tossing and turning for hours, I eventually made it to sleep and felt as if I was awake the entire time. My roommate said I talked in my sleep the entire duration of my slumber, and my dreams were very vivid and unsettling. I felt like a train wreck the next day until I could finally go home and sleep."
- Anonymous
- October 20, 2009
Diphenhydramine for Allergic Reactions "A little-known and rare side effect of this drug is a condition that would probably be called idiopathic thrombocytopenic purpura (ITP). This describes a serious depletion of platelets in the blood. The blood will not clot properly, and an injury can be life-threatening due to uncontrolled bleeding. It's rare, but if it happens and the cause is not figured out by your physician(s), this is a big problem."
- squ...
- July 18, 2009
Diphenhydramine for Allergic Reactions "I have severe allergies and life has been miserable. I couldn't afford the time or money anymore for allergy shots. Claritin stopped working. So did a bunch of over-the-counter allergy medications. I took so many cough and zinc lozenges my tongue became sore. I coughed all the time, to the point of stomach pain and incontinence. My coworker just gave me Benadryl. I was on the verge of going home sick, but now I'm 100% better. A stress rash that was erupting on the back of my neck just now went away. This is a marvelous product, and I didn't know it had so many uses."
- Cyp...
- Taken for less than 1 month
- February 22, 2021
Diphenhydramine for Insomnia "Have trouble getting to sleep and then wake and can’t get back to sleep. Tried Nytol, followed the instructions exactly, and am wide awake at 3 am, having gone to bed at 11 and not been able to sleep. Worse off than when I don’t take anything. Complete waste of money!"
- Fra...
- July 5, 2021
Diphenhydramine for Insomnia "Don't use this medicine if you have any history of mental health issues. Took me so long to realize this was making me so mentally ill, I was as close to committing suicide as I ever have been while taking this at a dose of 50 mg. Gave me serious shaking leg syndrome, but that I could deal with. The next day, I was so knocked out I almost didn't feel alive, the worst feeling I have ever had. I am so happy I read about antihistamines and how they affect the brain, they should be illegal. Crazy drug, but hey, someone's making a profit, so oh well! P.S. This is my experience. My mother uses Nytol and has no problem with it whatsoever, so I'm just pointing out to be careful, please."
- Ros...
- Taken for 2 to 5 years
- November 24, 2021
Diphenhydramine for Allergic Reactions "So I've been taking this going on 2 years now, and I regret taking it so long. I even ended up in the ER because my heart wouldn't stop racing, it was over 170. I believe it was due to the Benadryl. I ignored the side effect before I noticed that sometimes when I took it, my heart would beat funny, and it would be hard to catch my breath, but I kept taking it as it stopped my itchy throat, eyes, and mouth. Doctors at the ER found arrhythmia but said everything else looked fine. I stopped taking it, haven't taken it in a week, and I'm still having a racing heart and palpitations. Don't take this stuff long term. I'm in my early 20s and healthy if anyone reading this was curious."
- Jim...
- November 28, 2024
Diphenhydramine for Allergic Reactions "I ate a new spicy chip I had never had before (purple bag of Takis, for reference). One of the spices or something on the chip I'm allergic to and didn't realize it, and as I'm driving 45 minutes back home, my tongue began to swell up. I grabbed two Benadryl and chewed them the second I got in the door; 25 mins or so later. Literally, the worst taste I've ever experienced in my life, but I am here today to tell you about it. Within 5 minutes, the swelling started to subside, and I was no longer half-choking on my own tongue, and I made it through. I do not recommend you rely on this in the case of allergic reactions, especially if it's involving your breathing at all, but that is my experience with it. I was 45 minutes from a hospital by ambulance and had to act. And they're talking about banning it OTC... what a world."
- jen...
- Taken for less than 1 month
- March 22, 2023
Diphenhydramine for Insomnia "Beware!!! Had the worst night of my life. Hallucinated and ended up calling 911 to get to the hospital. My doctor confirmed it is the worst over-the-counter hallucinogen on the market. I have no idea how this is still available."
- Ali...
- Taken for 1 to 6 months
- February 10, 2021
Diphenhydramine for Insomnia "As an ex-drug addict, I've tried many things to help me sleep that are non-prescriptive. Promethazine (Sominex) does work, but the vivid dreams are horrendous, so be ready for wild nightmares. This was a symptom that is very common and does not seem to wear off the more you take, so be warned!"
- Twi...
- Taken for less than 1 month
- August 22, 2019
Diphenhydramine for Insomnia "Don’t work at all. Have used Ambien and zopiclone in the past to good effect but wanted something more natural, but these had no effect whatsoever. Total waste of money and time, and now can’t take anything else tonight as this is in my system! Would have been better to take one of the others in the first place."
- Zzz...
- Taken for less than 1 month
- September 26, 2022
Diphenhydramine for Insomnia "Desperately in need of sleep and decided to take ZzzQuil tablets. This product DOES NOT WORK! I tossed and turned, horribly restless, could not get any sleep! Heart pounding, pulse at high speed! Vicks must remove this product, like now!"
- Ale...
- Taken for 1 to 6 months
- February 1, 2020
Diphenhydramine for Insomnia "This pill literally does not work. I tried taking one every night, believing that it would work, and nothing happened. Got 3 hrs on a good night. Then I upped it to 2 per night, then 3, and after a few weeks, still nothing! Nytol is so useless, it's unbelievable. Absolute waste of time."
- Anonymous
- June 4, 2010
Diphenhydramine for Allergic Reactions "I have taken Benadryl or its generic equivalent for many years. It is very good for itchy throats and ears and all kinds of symptoms, and particularly good for sneezing. If the Benadryl doesn't work, then I know I'm coming down with something more than just seasonal allergies. I try to keep Benadryl with me all the time. There are so many food products that I am supposed to be allergic to that sometimes I take Benadryl before I eat, especially peanut butter and bananas, two of my favorite foods."
- Anonymous
- Taken for less than 1 month
- April 11, 2015
Diphenhydramine for Allergic Reactions "Experienced an allergic reaction during dinner at a new restaurant. Throat started itching terribly, so we left and drove to the nearest pharmacy. Used Benadryl syrup because I thought it would work faster. Fixed my allergic reaction in a minute."
- Sic...
- Taken for 1 to 6 months
- June 7, 2019
For Nausea/Vomiting "Have nausea often, especially if I undereat one day. I'll be nauseous and have trouble eating for days on end. I've been given Zofran, Phenergan, and Bentyl at the ER. When those ran out and the nausea didn't, I looked on the web and saw Benadryl recommended. It's worked very well for me every time! You will most likely be pretty sleepy, though. Plan on some nap time."
- Joh...
- October 31, 2020
Diphenhydramine for Insomnia "Basically, Nytol didn't work and had the opposite effect by keeping me awake, but I had a weird reaction too, as it made me feel fairly sick while I was lying in my bed, and that happened both times I took it. So it's into the bin with these tablets. I would be very cautious about taking this product, as most of the reviews are bad."
- Anonymous
- Taken for less than 1 month
- June 16, 2020
Diphenhydramine "My last 2 nights taking Nytol had the opposite effect on me. Took them to help me sleep for work. I normally doze off at 3 with my insomnia, with Nytol, it was 6 or 7. Missed two days of work. Won't be taking these again."
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Other brands
Benadryl, Banophen, Benadryl Allergy, ZzzQuil, ... +23 more
Professional resources
- DiphenhydrAMINE monograph
- Diphenhydramine (FDA)
- Diphenhydramine Capsules (FDA)
- Diphenhydramine Injection (FDA)
- Diphenhydramine Oral Solution (FDA)
Other brands
Benadryl, Benadryl Allergy, Diphen, Dicopanol
Diphenhydramine for Allergic Reactions "My adult-sized teenage son was given Benadryl IV, 50 mg, along with Compazine IV as a 'headache cocktail' in an emergency room in September of 2016. While there is no way to know for certain if Compazine or Benadryl caused the severe reaction he experienced, he has tolerated oral Benadryl just fine in the past. However, it seems important to share our experience based on the severity of his reaction that day and that multiple reports of similar exist. I do not recommend the 'headache cocktail' of Benadryl and Compazine together and hope the number of similar reports is looked into."