Diphenhydramine / ibuprofen User Reviews & Ratings

Brand names: Advil PM, Ibuprofen PM, Motrin PM

Diphenhydramine / ibuprofen has an average rating of 7.2 out of 10 from a total of 22 reviews on Drugs.com. 68% of reviewers reported a positive experience, while 18% reported a negative experience.

Condition	Avg. Rating	Reviews	Compare
Insomnia	7.1	21 reviews for Insomnia	113 medications
Pain	10.0	1 reviews for Pain	1148 medications

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Reviews for Diphenhydramine / ibuprofen

Sle...
November 11, 2015

Advil PM (diphenhydramine / ibuprofen) for Insomnia "I've never been the type to get a solid night's sleep. For years, I've slept 3 or 4 hours and woke up tired but unable to fall asleep. It truly made for days and days on end of being miserable. I've also never been a 'pill' person, so I never tried any kind of sleeping aid. One day, I simply decided to try some form of OTC sleep aid, and Advil PM was the first one I found. The difference it's made is amazing. I take 2 an hour before I plan to fall asleep, and I am out. No more tossing, no more turning, simply laying down and sleeping. For the first time in my life, I look forward to going to bed. The only drawback is, after 6 solid hours of sleep, I tend to wake up feeling a little out of it, but that goes away after my first few rounds of coffee."

9 / 10

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55 Report

Mum...
Taken for less than 1 month
February 12, 2019

Advil PM (diphenhydramine / ibuprofen) for Insomnia "After two years of insomnia, I was given a sample of Advil PM, and it was the answer to my prayers! Unless you’ve experienced the torture of insomnia, you can’t understand how precious a good night’s sleep is! It has also been a saving grace to me when I’m suffering from migraines. I’m so grateful to have this to go to when the going gets tough!"

10 / 10

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32 Report

JJa...
Taken for 1 to 6 months
August 4, 2020

Advil PM (diphenhydramine / ibuprofen) for Insomnia "So I’m 69 yrs old and for the last few years I’ve only been getting 5 hrs of sleep a night. I tried 2 Advil PM a year ago, and it knocked me out, but I was hungover the next day, so I stayed away from it because I couldn’t function that way the next day. Recently, I decided to try just taking 1 at bedtime, and that did the trick. I sleep for 8 hrs, and I’m not tired the next day. Alleluia!"

10 / 10

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24 Report

Pap...
Taken for 1 to 6 months
December 14, 2019

Advil PM (diphenhydramine / ibuprofen) for Insomnia "I am a 75-year-old male veteran in generally good health. Sleep apnea controlled by a C-PAP machine; however, rarely got more than 6 hours of sleep. Advil PM worked as a sleep aid for my wife, so I tried it with great results. Two Advil PM (NOT just plain Advil) have worked extremely well to pretty much guarantee me 8 hours of sleep. (Be advised that my wife tolerates me a LOT better when I sleep well!)"

8 / 10

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22 Report

sle...
February 8, 2021

Advil PM (diphenhydramine / ibuprofen) for Insomnia "I often work overnights and am also often jet lagged. After a while of this, I can no longer sleep 8 hours. Usually wake up after 4 hours. I bite one pill in half before I go to bed, and I sleep all night then. More than half, and I will feel hungover. Recommend not taking two as the directions say. Start with half, if no help, take the other half."

8 / 10

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12 Report

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Man...
Taken for less than 1 month
May 8, 2021

Advil PM (diphenhydramine / ibuprofen) for Insomnia "It works for mild case of insomnia. I feel tired at night but I have an over active mind that won’t shut down plus some neck pain and this makes it easy to sleep. Right around the 30-45 minute mark after taking it I’m falling asleep. Finally getting 7 hours!"

10 / 10

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8 Report

fin...
Taken for 2 to 5 years
August 16, 2021

Advil PM (diphenhydramine / ibuprofen) for Insomnia "It works well as a sleep aid, using a single pill. I've been using it nightly for a couple years but lately I've been extremely tired during the day. Other recent issues that are listed as possible side effects are an occasional underarm rash (looks similar to a burn) and swollen feet. I'm going to stop taking it, as perhaps the active ingredient has built up in my system."

5 / 10

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7 Report

Mor...
Taken for 1 to 2 years
December 5, 2020

Advil PM (diphenhydramine / ibuprofen) for Insomnia "I'm 67 yrs old and often wake up around 3-4 am to urinate. I then find it difficult to fall back to sleep when I need to get up at 6 am for golf 2x week. But if I take a 1/2 Advil PM 30 minutes before I go to bed I often don't wake up to pee, but if I do I fall back to sleep in moments. Been using for years if I have sleep deprivation issues more than 3 days in a row. If I sleep 7 hrs after taking, I am rested after my shower and ready to hit the links."

9 / 10

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7 Report

Dee...
Taken for less than 1 month
August 6, 2023

Advil PM (diphenhydramine / ibuprofen) for Insomnia "I switched from day shift to afternoons for 2 years and then back to days. I cannot regulate my sleep schedule. I wake up 5 or 6 times a night. I tried 2 of these pills and they knocked me right out and I slept right through. However, I felt extremely tired and foggy the next day and had to cancel going to a family function because of it. I will try a half pill next time. Do not take 2 pills as recommended."

10 / 10

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2 Report

Mar...
Taken for 1 to 2 years
June 29, 2023

Advil PM (diphenhydramine / ibuprofen) for Insomnia "I take this occasionally for pain, insomnia, or restlessness. One tablet usually gives me that push to fall asleep. So far, I haven't noticed any negative after-effects from taking it. I possibly feel a little extra groggy in the morning, but that usually subsides after having my coffee."

8 / 10

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1 Report

Luc...
Taken for less than 1 month
March 29, 2023

Advil PM (diphenhydramine / ibuprofen) for Insomnia "Couldn't sleep due to pain in neck. Got up and took two AdvilPM. I am a 72 year old woman. Was able to sleep but had dry mouth and got up and drank water and brushed teeth. When I woke up I felt nauseous and then threw up bile with some bright blood. Threw out the rest of the bottle of AdvilPM."

1 / 10

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1 Report

Tee...
Taken for less than 1 month
December 7, 2022

Advil PM (diphenhydramine / ibuprofen) for Insomnia "I have degenerative disc disease and lumbar spinal stenosis. I've been through cortisone injections, chiropractic, nerve ablation. Nothing helps for very long. OTC NSAIDs do nothing. Pain interrupts my sleep. I was desperate for sleep and so I took 2 Advil PM at 10:30 pm. Although it put me out, I literally could not get out of bed until after 2 pm the next afternoon! I woke up at 10 am and stumbled to the bathroom to use the toilet. After almost 12 hrs of sleep, I felt like I couldn't keep my eyes open, my heart was palpitating, my hands were slightly shaking. I fell back into bed and slept another 4 hrs until 2 pm!!! Even after getting up and getting dressed, I still felt fuzzy-headed. I can't take liquid NyQuil when I'm sick because it has the same affect on me. Bottom line, while Advil PM does put me to sleep, I can't stand the after-affects. I'll be looking for a natural pain/sleep aid in the future."

5 / 10

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1 Report

Pau...
Taken for 1 to 2 years
January 6, 2024

Advil PM (diphenhydramine / ibuprofen) for Insomnia "I'm a 69-year-old male. I've been taking half a tablet, no more than that or you will get dry mouth. I take it when I wake up to go to the restroom at 2-3 AM. 30 minutes later, I'm fast asleep and since I've been taking it, I have no pain anywhere. I do exercise and have been taking them for at least 2 years."

8 / 10

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0 Report

Pau...
Taken for 1 to 2 years
January 6, 2024

Advil PM (diphenhydramine / ibuprofen) for Insomnia "I'm 69 male, been taking 1/2 tablet, no more than that or you will get dry mouth. I take it when I wake up to go to the restroom at 2-3 AM. 30 minutes later, I'm fast asleep and since I have been taking it, I have no pain anywhere. I do exercise and have been taking them for at least 2 years."

8 / 10

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0 Report

Chr...
Taken for 1 to 2 years
June 3, 2024

Advil PM (diphenhydramine / ibuprofen) for Insomnia "I have been taking 2 Advil PMs off and on for over a year now and they work for me, and other sleep aids I've tried either don't work well or elevate my blood pressure, which wakes me up. When I get up in the morning, I have gotten about 7 hours of sleep, which is sufficient, and sometimes there is a groggy feeling that goes away in about 20-30 minutes after getting up."

9 / 10

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0 Report

Cas...
Taken for 1 to 2 years
November 1, 2024

Advil PM (diphenhydramine / ibuprofen) for Pain "Works for me! Amazing. Before, due to arthritis pain, I only slept for 2 or 3 hours per night. Now I can take 1 or 2 Advil PM and sleep for 8 or 9 hours. I wake up refreshed with no side effects. I guess, like everything, it works for some but not for others. Lucky me."

10 / 10

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0 Report

Pal...
Taken for 1 to 6 months
March 23, 2020

Advil PM (diphenhydramine / ibuprofen) for Insomnia "When I cannot get back to sleep after my regular meds only lasted 2 hours I try Advil PM. It does not work, or else takes a couple of hours for one or two hours of sleep."

1 / 10

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6 Report

Anonymous
December 24, 2019

Advil PM (diphenhydramine / ibuprofen) for Insomnia "Needed a sleep aide. Yes, Advil PM did its job. However, the next day I woke up extremely irritated and with a mild headache. It felt like I was hungover for the latter of the day. No Thanks!!!"

3 / 10

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5 Report

ero...
Taken for less than 1 month
November 17, 2022

Advil PM (diphenhydramine / ibuprofen) for Insomnia "I took 2 pills and waited for 5 hours hoping it would kick in. Tossing and turning all night. I was wide awake at 2am. Don’t waste your money."

1 / 10

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2 Report

GtG...
Taken for 1 to 6 months
April 18, 2022

Advil PM (diphenhydramine / ibuprofen) for Insomnia "Very positive experience taking 2 x blue Advil PM pills a night. No side effects and wake up feeling good. I am 61 Maie."

9 / 10

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2 Report

Tre...
Taken for 1 to 2 years
April 9, 2022

Ibuprofen PM (diphenhydramine / ibuprofen) for Insomnia "1/2 tablet 1-2 times per week only if you really really need it otherwise resistance builds and you will soon need whole tablet or more for same effect"

7 / 10

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1 Report

Ami...
Taken for 1 to 2 years
January 13, 2020

Ibuprofen PM (diphenhydramine / ibuprofen) for Insomnia "1/2 tablet works. 100mg"

10 / 10

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1 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.