Prempro User Reviews & Ratings (Page 2)

• Lis...
• October 29, 2013

"I started on Prempro on September 2, 2013, for my night sweats, hot flashes, and mood swings. I was on it for almost two months. The first month was fine, but during the second month, I developed way too many severe side effects. I had: swelling of hands and ankles, breast enlargement and pain, severe bloating, vaginal irritation, acne, my mood swings worsened, and I gained a lot of weight. The night sweats and the hot flashes got better, but the side effects were much worse than the night sweats and hot flashes. I started on Healthy Woman Soy Menopause Supplement, and it took care of the night sweats and hot flashes without all of the other side effects. This drug is definitely not for everybody, and my advice would be to listen to your body!"

• Anonymous
• Taken for 2 to 5 years
• October 25, 2021

For Postmenopausal Symptoms "It was a miracle for me. Within a week, I could sleep, have energy, and enjoy normal things again. I don’t get why I had to beg for almost 4 months to be allowed on it. Three years later and not a single side effect."

• pan...
• Taken for 2 to 5 years
• October 31, 2019

For Postmenopausal Symptoms "I was 52 when I started with the night sweats. Never had any hot flashes during the day. (Thank God) The night sweats kept me up and down most nights. After sharing this with my doctor, right away I was prescribed Prempro. It was a little expensive, but worth it. I took it for three years. Throughout the years, I began to have a menstrual cycle. I can recall having one for six weeks. I was in and out of the doctor's office frequently. The final conclusion was it was a side effect of the medication. I have been off of it now for six weeks, and things are not so bad at all."

• Anonymous
• August 25, 2011

"I have been on Prempro for 15 years. I am 57 now and have not had any problems. I call this my chill pill, it works great for me. Yesterday, my doctor took me off of it and gave me another pill called Activella. She said I have been on Prempro long enough and wants me to try the other pill. Wish me luck, I don't know anything about Activella."

• Anonymous
• Taken for 10 years or more
• June 7, 2022

For Postmenopausal Symptoms "I have been on Prempro for 25 years. Every time I try to wean myself off, I feel tired, moody, bones hurt, and not happy. My doctor thinks I should try weaning myself off again, my husband says, oh no... the world's not ready for that. I call it my happy pill. I’m 65, just tried again and decided if I am going to die, rather die happy than how I feel without it."

• Kat...
• Taken for 1 to 6 months
• May 14, 2022

For Postmenopausal Symptoms "I was lucky to not experience menopause until 55, but moderate hot flashes became annoying, so the doctor prescribed low-dose Prempro. At first, everything seemed fine, but after a couple of months, acne and weight gain ruined it for me. I was seriously waking up every couple of days with new pimples, and I've had good skin my whole life. Weight gain and bloating also started, and I've been thin my entire life. So no way I'm living with blotchy, bad skin and a pot belly to solve a few hot flashes."

• Mcm...
• Taken for less than 1 month
• November 19, 2019

For Postmenopausal Symptoms "So I was taking Remifemin, which wasn’t working for me, so I asked my doctor about HRT. I was having severe hot flashes at night, where I was soaking wet, and hot flashes maybe 3 to 4 an hour at 48 years old, and I’ve stopped my period pretty much eight months ago. I am on my fourth day and really haven’t seen a difference in hot flashes and night sweats yet, still bloated and very sensitive, like crying at really stupid stuff... lol. I’m looking forward to seeing how this medication works, but it is awfully expensive, but thank God I can somewhat afford it."

• SoC...
• Taken for 10 years or more
• October 15, 2022

For Postmenopausal Symptoms "I've taken Prempro for years since I was 45. I've always bought it from an online Canada pharmacy, Best Rx (with prescription). Recently ran out, didn’t think much of it. Had a doctor's appointment. Within 2 weeks, I've had the worst hot flashes and all other menopause symptoms. Honestly, couldn’t believe how uncomfortable. I ordered from Canada, but because of timing, had to pay (Walmart cheapest) $233 copay for a 28-day supply. 5 days with Rx, it’s getting better, still have unbearable heat flushes, but less of them. Ask the doctor for a written Rx, scan it to Best Rx, then go buy a 1-month supply. Stage your Canada purchases because it can take 4-5 weeks. It cost $98 for a 90-day supply, 10/12/22 just takes a while to get it and they send Premarin (Pfizer estrogen med) + progesterone, which is what I’ve taken as ‘Prempro’ for a decade. My doctor gives me 0.0625 /2.5 and said to take it every other day. My mother took Premarin until she was 85, could still ride a bike, great bones & skin!"

• Sam...
• Taken for 1 to 6 months
• February 8, 2021

For Postmenopausal Symptoms "After having a complete hysterectomy, I started hot flashes that same day of the surgery. At my 2-week post-op, I was a mess, wasn’t sleeping, hot flashes, crazy emotionally. My doctor started me on Prempro. Sticker shock on the cost, $206 for a 1-month supply! After a month, I felt great, sleeping and less emotional. A few months in, I started experiencing migraines and awful cramps in my legs. I didn’t want to go off Prempro, but the migraines were happening so often that I couldn’t get my work done, so I had to discontinue it after 6 months. I’ve since switched to a doctor that uses a compounding pharmacy and am trying to find the right combination of hormones."

• Chu...
• December 3, 2011

For Postmenopausal Symptoms "Took this medicine for 18 days. Hot flashes, nausea, and migraines disappeared after about a week. Then, on the 10th day, I felt nausea and a migraine come on, since then, no more symptoms. Not sure if it's okay to not take it anymore now that I feel better."

• Clo...
• Taken for less than 1 month
• March 12, 2019

For Postmenopausal Symptoms "I started the lowest dose of Prempro just 5 days ago. The GYN said it would stop/diminish the hot flashes, which in the last 5 months have been so debilitating I'm barely functioning. (Roughly every 45-90 minutes, for 8 minutes each, 24/7) I have been astonishingly moody, weepy, and fearful for the last 3 days, more than I can ever remember being since I was a teenager and new to my periods. However, I've lost most of my appetite, and although I feel 10x more stressed out inside, despite meditation and yoga, I will continue for as long as I can endure it because it's such a relief to be having fewer hot flashes. (Not gone, but maybe half as many!) However, at several hundred dollars per month for the drug, this won't last long. I figure I'll give myself a two-month break from hot flashes and then go back to suffering."

• Ter...
• Taken for less than 1 month
• July 10, 2024

For Postmenopausal Symptoms "I've been taking Prempro for the past month. The first week, my hot flashes got worse, but by week 2, they started to cool off. So far, I like what I'm feeling, but I can't sleep without my fan. I think I'm gaining weight. Today I got my second refill, and I started searching for more info. To be honest, what I read really scared me and made me rethink if I should continue taking it."

• hop...
• Taken for less than 1 month
• November 11, 2022

For Postmenopausal Symptoms "I am just starting on PremPro. My insurance charges over $670 a month due to the deductible. I looked at Canadian pharmacies, and it is a tiny fraction of the price! Everyone, you can Google Canadian pharmacies and get it CHEAPER! Get your doctor to give you a paper prescription, then you can email it to them in Canada! Good luck!"

• Jod...
• Taken for less than 1 month
• September 22, 2022

For Postmenopausal Symptoms "Day 3, and I am floored! My doctor didn't have high hopes that it would help with my depression/anxiety, but it has 100%! I can deal with stresses now. Moisture and sexual attraction have returned. I am sleeping through the night. I am not having moodiness and a short temper. I am able to concentrate and perform daily tasks. There is a mental clarity now. I just feel so well and happy! I am so grateful, I am saved! Side effects so far: mild headache, gas, and constipation. All are easily treatable. I also noticed that my hot flashes have increased a bit. I was managing those pretty well with Estroven, which I am still taking, but for some reason, I am getting them again. If I have to, I will live with them as long as I can continue to feel this peaceful. Aetna denied coverage, saying it isn't medically necessary for me, so I paid out of pocket. I am switching to United Healthcare next month, they cover it as a tier 3, still expensive but $100 vs. $140 out of pocket. Tough on the wallet, but worth it!!!"

• Anonymous
• Taken for 2 to 5 years
• August 4, 2021

For Postmenopausal Symptoms "Had a partial hysterectomy at 43 and went into full menopause. Sweat and felt like my back was on fire and burning pain down to my toes. Was on estrogen for 5 years and it really didn’t help, was put on the highest dose of Prempro about 7 years ago and everything went away. Then my oncologist retired 3 years ago, so my primary wanted me to wean off it, so I started dropping the dosage and was doing great. Then went to the lowest, doing so good I thought in April I could stop it. Boy, not a good idea going on the lowest dose again. Personally, it will be something I will take forever, as long as I can afford it. Cancer does not run in my family, so I feel safe and much happier on this med."

• Deb...
• Taken for less than 1 month
• September 5, 2019

For Postmenopausal Symptoms "Pros: Better mood, sexual functioning back to normal (great!). Cons: Every day terrible bloating, gas, and constipation. On the third week, sudden terrible water retention in legs made walking uncomfortable for me (I'm normally very athletic). I'm not sure if the severe migraine I had 10 days ago was the Prempro or not, but it's suspicious since I had to go in for injections on emergency for the first time from my headache specialist. I plan on NOT taking it in the morning and calling my doctor about the water retention. (I already called regarding the other side effects, but the edema occurred after that phone call today). Anyway, I was going to just ask for either a lower dose or an option a friend recommended (Bijuva). But now, I just want to switch meds altogether. This amount of edema just won't cut it for me!"

• Anonymous
• June 1, 2017

For Postmenopausal Symptoms "I had been on Enjuvia (plus a progesterone supplement) for 3+ years, and they worked fantastic from day one! Unfortunately, they have stopped making it for reasons I can't find. I was put on Divagel, and I gained 15 pounds in 3 weeks, plus the leg (including my foot) I put it on swelled up like a balloon, among other side effects. I have been on Prempro for 6 days now, and my hot flashes/night sweats are worse than ever, but all my other 'problems' seem to be okay. The doctor's office said to give it a month, wish me luck!"

• cbe...
• April 5, 2012

For Oophorectomy "I am 22 and underwent oophorectomy surgery following 2 massive ovarian cysts on each ovary. Right out of surgery, I was prescribed Prempro and had to take it. I experienced hot flashes for the first few days. The doctor told me that if I felt bloated, I could skip a week and I would have a small period, which I have done. I had cramps and sporadic bleeding, but the bloating never went away. I have gained a lot of weight that has been really hard to lose, and I have been on this medicine for only 3 months. I also have really bad acne all over my face that I haven't had since junior high. Once I go back to the doctors, I will be asking to try another hormone replacement therapy."

• Sun...
• Taken for less than 1 month
• February 21, 2021

"I enjoyed reading all the comments. I literally took my first pill last night. I will be 50 in August, and for the last 2 years, I’ve had hot flashes, day and night, can’t sleep, and terrible leg cramps where I would need to get up in the middle of the night and walk. My doctor suggested I take it at night at the same time every day! She wants to see me in 4 weeks because my blood pressure was a bit high at my appointment. Never had an issue with my pressure. I think I was just nervous. I hope my experience will be a good one!"

• Kik...
• Taken for 1 to 6 months
• August 10, 2018

For Postmenopausal Symptoms "I was prescribed Prempro by my gynecologist in April 2018. After taking it for one week, my period came, and I had a huge bald spot on the side of my head! I only took it for a week, I stopped, and now here I am, 4 months later, the back of my nape area, my hair is all gone!"

• cyn...
• Taken for less than 1 month
• November 8, 2020

For Postmenopausal Symptoms "I am 52, and I've tried everything for hot flashes, nothing really works, so my GYN tested my prolactin levels. They were pretty high, and that causes hot flashes. I recommend checking prolactin levels. Also, I have tried Prempro, but it made my throat itchy, possible allergic reaction. Anti-anxiety medications helped me with my hot flashes a lot."

• Mrs...
• Taken for less than 1 month
• October 11, 2022

For Postmenopausal Symptoms "I am 47 years old and perimenopausal and have felt horrible before now, day 2 of using Prempro. I was in constant PMS, heavy bleeding, mood swings, and depression. Yippee, the bleeding has stopped and feels like the weight of the world is off my back."

• Ano...
• Taken for 1 to 6 months
• January 1, 2025

For Postmenopausal Symptoms "I’m 54 and have been experiencing menopausal symptoms since I turned 50. After 4 years of suffering from hot flashes, night sweats, sleep deprivation, and worsening vaginal dryness/discomfort, I decided to start Prempro at the lowest dose. I’ve been on it now for about 6 months. After 2 weeks of taking it, my hot flashes and night sweats were completely gone. It was truly amazing. My sleep and my vaginal symptoms improved too. However, after about 3 - 3 1/2 months of taking it, I noticed significant hair loss. I thought my body just needed more time to adjust, so I kept taking it and my hair kept falling out, and it didn’t let up. It’s become so thin. Now I’m in the process of weaning off of Prempro because I don’t want to go bald. It’s so depressing because it was helping me in every other way. But it’s either go bald and feel good or keep my hair and feel horrible. Again, depressing."

• Anonymous
• Taken for 6 months to 1 year
• February 21, 2022

For Postmenopausal Symptoms "Have been on Prempro for almost a year. Did help with the hot flashes. I do experience a lot of headaches. I have also had a lot of hair loss since taking this. Just got a letter from my pharmacy saying they will no longer pay for Prempro and giving me covered alternatives, such as Estradiol-norethindrone acetate, Fyavolv, Jinteli, Mimvey, and norethindrone-ethin estradiol. Does anyone take any of these HRT alternatives? If so, what is your experience? Also, has anyone had hair loss from Prempro or any other HRTs?"

• Anonymous
• Taken for 1 to 6 months
• January 13, 2022

For Postmenopausal Symptoms "Doctor had me on Premarin for a year, worked great. Doctor then switched me to Prempro. Only took for a month and a half, was having leg cramps and a period after no period for 5 years. I’ll try a supplement instead."