Prempro Interactions
There are 313 drugs known to interact with Prempro (conjugated estrogens/medroxyprogesterone), along with 25 disease interactions, and 6 alcohol/food interactions. Of the total drug interactions, 53 are major, 239 are moderate, and 21 are minor.
- View all 313 medications that may interact with Prempro
- View Prempro alcohol/food interactions (6)
- View Prempro disease interactions (25)
Most frequently checked interactions
View interaction reports for Prempro (conjugated estrogens / medroxyprogesterone) and the medicines listed below.
- aspirin
- atorvastatin
- bupropion
- clonazepam
- Cymbalta (duloxetine)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- folic acid
- gabapentin
- hydrochlorothiazide
- levothyroxine
- Lipitor (atorvastatin)
- lisinopril
- losartan
- Lyrica (pregabalin)
- meloxicam
- metformin
- Nexium (esomeprazole)
- omeprazole
- pantoprazole
- prednisone
- simvastatin
- Singulair (montelukast)
- Synthroid (levothyroxine)
- tramadol
- trazodone
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Zyrtec (cetirizine)
Prempro alcohol/food interactions
There are 6 alcohol/food interactions with Prempro (conjugated estrogens / medroxyprogesterone).
Prempro disease interactions
There are 25 disease interactions with Prempro (conjugated estrogens / medroxyprogesterone) which include:
- abnormal genital bleeding
- abnormal vaginal bleeding
- carcinomas (estrogenic)
- hypercalcemia in breast cancer
- hypertension
- thromboembolism/cardiovascular
- hepatic neoplasms
- bone mineral density
- menstrual bleeding
- breast malignancy
- liver disease
- thromboembolism
- angioedema
- gallbladder disease
- hypercalcemia
- hyperlipidemia
- liver disease
- melasma
- depression
- fluid retention
- glucose intolerance
- retinal thrombosis
- thyroid function tests
- hyperlipidemia
- weight gain
Report options
More about Prempro (conjugated estrogens / medroxyprogesterone)
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- Side effects
- Dosage information
- During pregnancy
- Drug class: sex hormone combinations
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
