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Buspirone and Tiredness: What Users Say

Brand names: BuSpar

Tiredness: mentioned by 76 users (5.6%)

Based on user experiences from 1,358 Buspirone reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

dizziness 19.2%
anxiety 11.9%
nausea 8.2%
headaches 7.2%
insomnia 7.0%
tiredness 5.6%
panic attacks 5.0%
lightheadedness 4.3%
drowsiness 3.8%
depression 3.7%

Reviews for Buspirone

Commonly mentioned side effects
  • A12...
  • Taken for 1 to 6 months
  • July 5, 2021

Buspirone for Anxiety "BuSpar was the first drug after 7 SSRIs that truly saved my anxiety. I thought I was never going to get better. I was plagued by anxiety and panic so badly every day. Benzodiazepines worked but were only able to be used for the short term. I could feel it working in my brain after one dose. It continually got better. Some minor dizziness & feeling tired. Other than that - anxiety gone. Thank the Lord!"

10 / 10
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1059 Report
  • Kat...
  • Taken for 2 to 5 years
  • January 27, 2021

Buspirone for Anxiety "I have anxiety from the time my eyes open to the time I close them to sleep (if I can). When I was prescribed BuSpar 10mg, my whole world changed. I can now function and my social anxiety is much better. My OCD is moderately managed along with therapy. But the anxiety is tremendously better. I do need to take it with food or I get very tired. But with a little food, I don’t notice it. And it’s perfect for helping me sleep at night. I have panic attacks far less often now too, and I’m more comfortable with this medication than the highly addictive benzodiazepines."

8 / 10
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387 Report
  • bst...
  • December 4, 2014

Buspirone for Anxiety "I'm on week 7. I thought I would wait until the effects kicked in to write a review. Regarding the side effects, mild nausea and lethargy for a short while after taking the medication, nothing to avoid taking the pill for. As for the results, very mild, but I notice a difference. I speak more clearly and confidently to people, and I am overall less anxious. One big thing, my constant worry about my health has subsided. I am 31 and live a healthy life, but I get a stomach ache and think I have colon cancer. These thoughts I laugh at now. I recommend taking this. Only 8 stars because it is not a cure all, only you can be."

8 / 10
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455 Report
  • Ant...
  • February 8, 2014

Buspirone for Anxiety "I don't like SSRIs. The fact that BuSpar can deal with serotonin receptors without causing the loss of libido, weight gain, and tiredness makes it perfect to treat generalized anxiety. Plus, it's non-addictive unlike many benzodiazepines for panic attacks. I wish they made it in extended-release form, though my doctor said it's okay to just take my full dose in the morning - and that seems to be working fine for me. It's the only medication that focuses mainly on the brain's serotonin levels that I like."

8 / 10
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249 Report
  • Dan...
  • August 1, 2020

For Anxiety "I had been taking Buspirone on and off for about a year at a dose of 5mg-15mg per day and felt disappointed after all I had read it could do. It did have a numbing effect on the GAD but it was definitely still there, and I felt more tired than it was really worth. However, my doctor and I pushed the dose to 40mg/day, and that's when it really started to work (like flicking a switch). The GAD is gone like it was never there (which is strange at first but also wonderful), and I am really no more tired than at 15mg (feeling better gives you a lot of energy). Buspirone isn't the one for everyone, but it can be life-changing."

10 / 10
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121 Report

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  • Ano...
  • Taken for less than 1 month
  • January 25, 2013

Buspirone for Panic Disorder "I have taken this medication for a month, and in that time, I have had the quietest mind of my life. I take Lexapro for my regular medicine, and this is for easing the generalized anxiety disorder that acts up so frequently. Never have I been able to stop myself from a panic attack like this. It's amazing. The first week was tiring and disorienting... after that, smooth sailing."

10 / 10
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240 Report
  • Anx...
  • Taken for 1 to 6 months
  • March 27, 2015

Buspirone for Anxiety "In a nutshell, even though I did not want this drug to work because I hate taking medicine, it really does help me! I refuse to take benzos. My therapist talked me into trying BuSpar. It made me really tired at first. But honestly, now that I look back, I think it did that because it seemed to slow my racing mind down. So naturally, once I relaxed a bit more, my body finally could rest. My anxiety is not gone. But when I am in a place where I feel safe, I am able to relax and my mind isn't so noisy. It is a strange, new feeling."

8 / 10
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145 Report
  • Mou...
  • Taken for 6 months to 1 year
  • May 16, 2015

Buspirone for Anxiety "My son is in high school and has taken this for 7 months. It changed his life. His anxiety over school was out of control to the point he had to be integrated back into school. He tried Ativan and had horrible side effects, and he was reluctant to try anything else after that. After about 3 months on the BuSpar, he walks tall into school. No more looking over his shoulder or panic attacks out of nowhere. We wish he would've taken this years ago. The only side effect he complains of is tiredness and occasional headache. The tiredness was more so in the beginning. Those side effects are minuscule compared to his anxiety before taking BuSpar."

9 / 10
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133 Report
  • Isn...
  • Taken for 6 months to 1 year
  • July 4, 2016

Buspirone for Panic Disorder "I've been on this medication for about eight months for both panic disorder and anxiety, 30 mg twice a day. Just so people know, it takes roughly six weeks to kick in fully, so if you haven't felt anything yet, you need to give it time before you try something else. While it does make me very tired after I take it for about 30-40 minutes, it doesn't make me chronically tired like I was while on antidepressants. A short nap definitely helps if I'm not doing anything in the morning. It's absolutely brought my level of anxiety way, way down to a manageable level, especially after getting to the maximum dose. I'm functioning normally for the first time in years and I love it."

9 / 10
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112 Report
  • Jus...
  • Taken for less than 1 month
  • May 9, 2012

Buspirone for Anxiety "After trying SSRIs and other medicines, I have finally found BuSpar, and it has changed my life in less than two weeks! I have had mild to moderate anxiety for a few years, and now that I'm taking BuSpar (I only need 15 mg/day in divided doses), I feel normal again. My mood is more positive, and I laugh/am happy more even in this tough economic time! No major side effects. The first couple of days it made me a little tired, and that's it. I really started noticing changes about 8-9 days, I could feel a huge difference, and the anxiety is GONE! This is a safe medicine to take (non-habit-forming), and I would recommend it to anyone. It has changed my life, thank you BuSpar."

10 / 10
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121 Report
  • Jac...
  • Taken for 2 to 5 years
  • March 6, 2022

Buspirone for Anxiety "Buspirone saved my life! Several times in the past years. It's a lifesaver and life changer. I was terrified to start taking it at first due to the horrible reviews I would read, but everyone's different. And I really needed help with my severe anxiety/panic attacks, so I started taking it and hoped for the best. It was the best decision I've made. I started taking 7.5 mg twice a day and felt the difference the next day, taking 15 mg twice a day when needed to. I had mild side effects for the first week: headaches, tiredness, vivid dreams, but all tolerable. The first 3 days being the worst, but went away. Within the first week, I felt so much better and just got better after that. Felt more calm, less anxiety, no overthinking, no more intrusive thoughts, better sleep, and it's not habit forming, which is a plus for me. It really works, I recommend it if you really want to help yourself. Don't be scared of the side effects or reviews and push through it. It really works. I'm so thankful for it."

10 / 10
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38 Report
  • A...
  • Taken for 1 to 6 months
  • September 10, 2019

Buspirone for Anxiety "This medicine is very good for long-term control for GAD. I also take 900 mg of gabapentin with the 30 mg BuSpar daily. New laws and good reasons forbid benzos long-term. I still take 2 mg of Xanax during panic attacks, which after months on BuSpar are very rare. Give it a try, it's a funny med-30 mg you're fully up, and 30 mg later tired, but a good relaxing kind. Takes a while for it to help though. My advice, if you have anxiety, is to get off benzos, they will ultimately ruin your life and brain."

8 / 10
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63 Report
  • Ano...
  • Taken for 1 to 6 months
  • July 21, 2019

Buspirone for Anxiety "The side effects of BuSpar for me were worse sleep, anger, weight gain, and tiredness. My anxiety got worse, I had an erratic heartbeat, and it made my eyes feel really weird. This drug made me completely dysfunctional, exhausted, nauseous, and also out of it. So distracted, and it made my ADD worse."

1 / 10
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57 Report
  • Ano...
  • Taken for 1 to 6 months
  • July 21, 2019

Buspirone for Anxiety "The side effects of BuSpar for me were worse sleep, anger, weight gain, and tiredness. My anxiety got worse, I had an erratic heartbeat, and it made my eyes feel really weird. This drug made me completely dysfunctional, exhausted, nauseous, and also out of it. So distracted, and it made my ADD worse."

1 / 10
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57 Report
  • Nad...
  • Taken for 6 months to 1 year
  • August 13, 2019

Buspirone for Anxiety "For me, BuSpar works pretty well on the physical symptoms of anxiety. What I mean is that, unlike the SSRI that worked for me in the past, I still have the thoughts that cause the anxiety (the SSRI seemed to squash any negative thoughts), but at least my heart isn't racing, I don't have that deep sick feeling in the pit of my stomach, and I'm not sweating like crazy. I do feel pretty lazy and tired on it though. Better than getting hooked on a benzo, and at least I can get some sleep. It has minimal side effects on me, which is what we expected with my Genesight results."

8 / 10
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56 Report
  • Jak...
  • Taken for less than 1 month
  • June 20, 2023

For Anxiety "Started for GAD. Worsened my paranoia, made me incredibly dizzy and exhausted constantly, all while making me unable to stay asleep at night. Took for two weeks before having a psychotic episode and quitting. Felt better within 48 hours. Not a good medication if you also experience depression, delusions, or psychosis."

1 / 10
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23 Report
  • Mad...
  • February 19, 2020

For Anxiety "Not going to lie, I had this about a year, almost 2. I noticed when I am on this, I am more irritable, I have restless nights where I don't fall asleep or stay asleep. I noticed that my mindset has completely changed negatively, and it doesn't keep me calm or relaxed. I feel more nervous or anxious. I noticed if I am off of them, I get more emotional. I am telling you, this is not the medication for you, especially if you take half. I think it messes with my breathing too. I am more tired and low energy when I take this."

4 / 10
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52 Report
  • Ste...
  • Taken for less than 1 month
  • August 9, 2013

Buspirone for Anxiety "I recently started having panic attacks and was diagnosed with generalized anxiety disorder. My doctor put me on Prozac, but after 5 days, I was having such horrible side effects that she switched me over to BuSpar 5mg in the morning and 5mg in the evening. I am to up my dosage after 5 days to 7.5mg in the morning and then again in the evening. However, I feel dizzy, upset stomach, and just exhausted. My doctor told me to give it time because I'm coming off a medicine and starting a new one at the same time. It is worse in the morning. I just want to feel better. I've had to take half of my 0.5mg Xanax just to take the edge off every day and have zero appetite. I'm feeling hopeless and need some encouragement and help."

3 / 10
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82 Report
  • Anonymous
  • Taken for less than 1 month
  • June 10, 2012

Buspirone for Anxiety "Before BuSpar, my anxiety from post-traumatic stress disorder was very out of control. Xanax and Ativan barely touched it. My constant anxiety led to a suicide attempt because I was in constant fear, which felt like constant panic. I've taken BuSpar 15mg 3x a day for almost a month now, and I have my life back. The only side effect is a little tiredness. But I will take that over what my life was like."

8 / 10
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80 Report
  • Wor...
  • Taken for 6 months to 1 year
  • March 3, 2016

Buspirone for Anxiety "My doctor prescribed due to its low dosage. And that I didn't want to take meds. I became so helpless after years of trying to cope with anxiety on my own, I finally reached a point where medicine was my only hope. It kicked in quickly, my obsessive thoughts stopped, then the dosage would wear off, so I started taking a higher dosage. Then it made me become upset, super emo crying, not myself, and finally realized it was BuSpar. Cut back dosage again. It made me tired all the time, couldn't concentrate, weird dreams, and loss of interest in things. Was not a good fit, I finally had to ask the doctor for something else after a year. It didn't work altogether except for stopping obsessive thoughts. It also gave me brain zaps, memory loss, and space cadet syndrome."

2 / 10
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64 Report
  • Wwe...
  • December 30, 2015

Buspirone for Anxiety "Wait 6 weeks, but it helps before then too. I have been on it at 25 mg a day for a year. Just recently, I have been in a traumatic situation, and I ramped up the dosage to 40/50 mg to help. It has been a huge help, and I only have taken 2 Ativan during this three-week ordeal. I think BuSpar for me makes me tired when I am not anxious and is a huge help when I am. It seems to cut the adrenaline levels, and that is what works for me without the sexual side effects that SSRIs have."

10 / 10
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53 Report
  • Anonymous
  • October 7, 2009

Buspirone for Anxiety "A little over 2 years ago, I started feeling anxiety thinking of bad things that would happen to me or my family. I would worry about these things every day, and then I would have trouble breathing, and it was all due to anxiety. My doctor prescribed BuSpar, and everything went away. I felt normal and stress-free, and the feelings I had went away. I also read BuSpar is for short term, but as long as your doctor prescribes it for you, you should take it as long as you need to. Without it, I would be a wreck. As for side effects, I get dizzy and tired. I take one 15mg at night and the other in the afternoon after work, and take about a 30-minute break to lay down or just watch TV. I feel much better after that."

10 / 10
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75 Report
  • joe...
  • August 8, 2018

Buspirone for Anxiety "My doctor prescribed BuSpar 5. I felt drugged with no energy. Now taking 2.5 twice a day and feel more relaxed and energetic. Experiment with different doses before you give up. The doctor doesn't have a clue what dose you can tolerate, as everyone is different."

5 / 10
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41 Report
  • Alf...
  • Taken for less than 1 month
  • October 21, 2019

For Anxiety "Been taking buspirone for 3 weeks, 7.5 mgs 3 times a day. Helped tremendously with my generalized and social anxiety. First week or so had side effects consisting of headaches, dizziness, tiredness, and lack of motivation throughout the day. But that all went away with the exception of slight dizziness for 30 mins or so after taking it. When it happens, it comes and goes fast. Doesn't always happen. My anxiety is almost non-existent. I can concentrate better, especially in conversations, which before, my mind would wander then race when talking to others. This turns into anxiety attacks. Buspirone helps my mind stay focused on the conversation. I'm more confident in these situations. So far, this drug is exactly what I needed."

10 / 10
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33 Report
  • Anonymous
  • January 12, 2010

Buspirone for Anxiety "I started taking BuSpar for my anxiety, and it made me very dizzy and tired. It also made my arms tingle, and I started getting terrible headaches every time I took it. My anxiety just got worse while taking it because I was worried about the side effects it was causing."

1 / 10
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60 Report

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