Wellbutrin SR and Tiredness: What Users Say

• Anonymous
• Taken for 1 to 6 months
• February 17, 2013

For Depression "I have ADD, anxiety, and depression. I began 100mg once a day for a week then went to 100mg twice a day. You have to give this medicine time to work. The first week I was thinking of not taking it anymore because it made me feel so tired. But I'm so happy I stuck it out! My overall mood, attitude, and outlook have improved tremendously. My mood and attention are consistent, unlike when I took Adderall and would experience crashes. This medication has made a world of difference. I'm less anxious and happier."

• Pin...
• Taken for less than 1 month
• January 30, 2014

For Depression "I started Wellbutrin SR just last week. I feel 90% better already. Previously I was taking Zoloft and after a year and a half, I felt sluggish, tired, hopeless, and just plain blah. I now don't have constant worrying, it helps with my OCD, and the things that bothered me before have just become basically no big deal to me. I'm happier, I focus much better. And my spirits are brighter than they have been in months!"

• Emi...
• Taken for less than 1 month
• October 19, 2013

For Depression "I am only on my 3rd day with Wellbutrin SR (150mg once a day for now) but I really feel good about this medicine already! I'm brand new to antidepressants but had been on Lexapro for 2 weeks prior to getting the Wellbutrin prescription, and I really did not like the Lexapro. With it, I had been having a headache every day, tense muscles, felt emotionally numb, was tired all the time, couldn't focus, and absolutely could not reach orgasm even having sex every day (which was extremely frustrating). Since switching 3 days ago, I have had more energy, more ability to focus, I feel happier about life as a whole, and I have been really productive with school work (I'm a college student). I also have noticed that I'm not feeling as hungry. Good feels."

• Ron...
• Taken for 2 to 5 years
• May 2, 2017

For Depression "This medicine has been the best at treating my depression. I've tried Prozac, Pristiq, Effexor, and Trintellix, and Wellbutrin's stimulating properties are what have made this drug so effective for me. Every other antidepressant I've been on has made me feel drugged, zoned out, and tired. Probably the best out of all the other antidepressants I tried was Effexor, but even then, it triggered what I now believe to have been manic episodes. The sad thing is that this drug is no longer effective for me after 3 years."

• Anonymous
• November 29, 2008

For Depression "I tried various other anti-depressants. I have severe depression, which runs in my family. Wellbutrin works well for me. The only noticeable side effects have been twitching and some sleeplessness. It is expensive, though. The generic was just terrible. Gave aching, even more twitching, tiredness, lack of concentration, etc. I would not recommend the generic, as many other people had similar complaints. I do recommend Wellbutrin SR NON-GENERIC, especially if you have insurance."

• D-0...
• Taken for less than 1 month
• May 1, 2015

For Depression "I've been on the generic version of Wellbutrin SR 100 mg once a day a little over a week. Added to supplement my 20 mg Prozac twice a day and 0.5 Klonopin twice a day. I've been on the Prozac and Klonopin for over a year, and it began to be not as effective. I began to feel very depressed along with my anxiety, also, I've gained about 20 lbs, so my psychiatrist prescribed 100 mg Wellbutrin SR once a day in the morning to help. So far, I've noticed I'm extremely tired about 1 hour after taking it, so tired even my strongest cup of coffee can't keep me awake. I know Prozac and Klonopin can have this as a side effect, but my body is well adjusted to that now, those side effects are long gone. I've noticed better focus and reduced appetite, so now I will just wait."

• 17...
• December 19, 2010

For Depression "I have been on this medication for less than a month already, and to be honest, I still haven't noticed anything too big yet. I have severe depression and have tried four other medications, and all they did was make me tired and antisocial. With this, I don't fall asleep during class or eat a lot, but I still feel like I'm not completely here. I feel sad, and I have been crying a lot over small things, but I'm still giving it time, and I feel confident about this."

• Mis...
• July 30, 2016

For Depression "I rated it a 5 because I felt for me it was 50/50. Tomorrow will have been only my 5th day taking the generic version (bupropion SR), but I am making today the last one. I was prescribed only 150 mg once a day. The first 3 times I took it, it worked wonderfully. I experienced a handful of side effects that were super mild, but I felt great. I felt energized and positive. Today, on the other hand, about two hours after I took my dose, I was hunched over the toilet, almost throwing up with bad stomach pain in addition to the nausea. I never threw up. I have ZERO appetite and no energy and a bad sharp pain in my upper stomach. I feel totally disconnected from my body."

• Anonymous
• September 8, 2010

For Depression "I have been taking Wellbutrin SR 150 mg for five years. Have been doing really well, but here lately I have been really tired, low sex drive, wanting to eat when I am not hungry. Maybe I need an increase."

• Ht1...
• Taken for 1 to 6 months
• August 10, 2018

For Depression "Switched to Wellbutrin after being on Zoloft for two years, and it has been awful. I suffer from depression, PTSD, and anxiety. Wellbutrin has made me extremely irritable, and I'm constantly tired."