Wellbutrin for Major Depressive Disorder User Reviews (Page 5)

• Anony...
• Taken for 1 to 6 months
• August 22, 2021

"Currently on this medication 150mg daily. I expected the side effects to be bad after reading some reviews here and they were lol. Thought so many people said it would calm down after the first month but it's been longer than that. Usually for me the nausea is the worst thing. I never want to eat anything, food just disgusts me most of the time now. I felt like it was really helping the depression a few weeks ago but now I am more suicidal than ever. Also my anxiety is horrible. Many days I don't want to leave the house. I used to be agoraphobic about 10 or so years ago (in my teens) and now I feel myself heading that direction again. It also has really affected my sleep. Or at least that's what I'm assuming. I have been having a very hard time getting to sleep and then if I wake up from something it's even harder to fall back asleep. It just sucks. The only plus is that it doesn't increase my appetite. Hope this helps."

• bummer
• Taken for 1 to 6 months
• September 4, 2022

"I had a great experience the first three months, it helped keep me up during the day which was nice. Did nothing for my sex drive but that was zero when I started. Then it was like a switch flipped, after the third month (at 300mg) I was suddenly back to sleeping 14 hours a day, had nausea all the time, and when I was up I was having awful panic attacks. And oh my god the irritability, I was going to hurt someone or myself. I've had bad reactions to most pills, but that was a pretty big disappointment, because I did feel great for three months. My psych handled it poorly and wanted me to wait two more months for an appointment soooo I quit cold turkey. And while that was stupid and I don't recommend doing that without the help of a medical professional, I experienced no withdrawal symptoms. I will say I feel better now than I did before starting welbutrin, probably due to diet improvements and establishing an exercise routine."

• Gweni...
• July 30, 2017

"This is for Anxiety/major depressive disorder and BPD. The side effects suck. Since I've been on Wellbutrin I've had severe dizzy spells and severe insomnia where I stay up all night and get 2-5 hours of sleep in the morning, on good days. My appetite is suppression is not as extreme as other medications I've been on but I have lost 5 pounds on it. I like eating so I don't like that. I had my first self harm episode and it had been over a year and it was over something insignificant that happens all the time. It gave me depression. I personally haven't experienced a good thing about this med but I'm giving it another month or two to work. I'm hopeful."

• Anonymous
• Taken for 1 to 2 years
• December 17, 2016

"I started taking Wellbutrin (150mg) during an extreme depressive episode. It helped even me out a lot, though it didn't address all of my symptoms. I increased the dose to 300mg but had to drop back down because I was having trouble sleeping. This is the only side effect I've experienced while on this medication. I've been on it for a year and a half now and overall it has helped a lot. I'm still depressed but I'm no where near as bad as before taking Wellbutrin. I'm looking into adding an SSRI or something as an adjunct therapy to try to make things even better."

• Alexa...
• Taken for 1 to 6 months
• November 23, 2017

"Was put on this after I went to the psych ward for suicidal thoughts and general depression. Before this I was on Prozac for 3 weeks, stopped taking it due to increased anxiety and extreme binge eating that I never had before. After that my doc switched me to 20 mg Celexa. Took that on and off for over a year... it helped slightly with anxiety but quickly became as effective as taking sugar pills. I started on the generic SR, 2 a day and with that I had slight ringing in the ears, some random panicky feelings. But my mood had improved tremendously, plus my sex drive went way up after just 1 day! My appetite control is great. On 300 mg XL generic now and side effects are subsiding. Had worries about seizures but that's rare. 0.3% incidence."

• Anonymous
• Taken for 1 to 6 months
• November 16, 2016

"Was started on Wellbutrin 150mg for one month. Made me sleep and eat less but did nothing for my depression so my doctor increased it to 300mg. Within 3 to 4 days of the increase, I was having panic attacks and couldn't stop crying. Depression kicked into overdrive immediately."

• JC23
• Taken for less than 1 month
• July 30, 2017

"I was prescribed Wellbutrin 2xday after Celexa stopped working after being on it 5 years. Within a few days of taking the Wellbutrin my anxiety was back and depression was worse. Had trouble staying asleep because my mind was constantly racing. Definitely did not work for me."

• Insal...
• Taken for 1 to 6 months
• December 18, 2021

"I got this medication prescribed for MDD, ADD and as an aid to quit smoking and since I heard a lot of positive reviews on the internet I was hyped, but I've been on 150mg for 3 months, 300mg for 2 months and 450mg for 1 month now and I don't notice a thing. Just as suicidal as ever, maybe even worse, since I'm so disappointed. It's the 4th anti-depressant I've tried so far and nothing works."

• Bupro...
• Taken for 1 to 6 months
• April 19, 2022

"It didn't really help at first, until I gave it 6 weeks and my doctor upped my dosage from 150 mg to 300mg. Everybody is different, I'm just saying what seems to be working for me. I was very suicidal after coming home from the hospital and coming cold turkey off of venlafaxine. I was on an extremely high dose of venlafaxine (375 mg. of XL daily) a previous doctor was prescribing. I lost that psychiatrist and because I was extremely psychotic partially because of the venlafaxine, ( I Think) and had to go to the hospital and be put on Haldol which has been very effective at treating my psychosis. I am also on buspar (15 mg. daily ) and ecitalopram. The buspar is very safe and is helping me, anyways, a great deal with my anxiety. Today, I'm not so sad or nervous as I was a few months ago. I'm sharing what's helping me in hopes that it might help someone out there.Thanks! Sincerely, from someone who has suffered a great deal from chronic depression, psychosis, and generalized anxiety disorder."

• slam
• Taken for less than 1 month
• March 8, 2019

"I suffering anhedonia for 1.5 years I don't feel happy, but no angry or any other emotion. I heard about wellbutrin and I got some of hope so I asked my doctor to give it a chance. Day 26 I feel horrible. I felt the same 2 weeks ago I though these side effects will go away and it will be my life saver because is a dopamine inhibitor. I was hoping it works but now I feel completely hopeless I don't know if give it more time or get off this drug it is my last resort. Other antidepressants just make me feel worse wellbutrin too but some days I've been feeling a little of hope and more energy. I don't know what to do anymore"

• MrCage
• Taken for less than 1 month
• November 18, 2015

"I started taking Wellbutrin for my depression, and it was the first medication that I have tried. The first week and a half or so was uneventful and I barely felt any change. After that, things went downhill. I began having major mood swings - I would go from being happy and energetic one minute to so depressed I would break down crying and couldn't even motivate myself to do anything to being angry and agitated for no apparent reason. I also began to "space out" at random times, myself or my friends and family would catch me staring at the floor for minutes at a time. I also had a sort of out of body experience where I lost my sense of self and felt depersonalized for about 15 seconds. I ended up stopping the drug after just under a month."

• Anonymous
• Taken for less than 1 month
• February 18, 2022

"I had high hopes starting on Wellbutrin given that it was much different than the previous antidepressants I had tried. The side effects though within just the first two weeks were awful. I had dealt with many medications side effects before, but with this, I could not stop shaking and my heart was constantly racing (120+ bpm constantly). I was throwing up, yet also not hungry at all. On multiple occasions, I almost passed out, feeling almost feverish. I had wanted to stick it out and see if they went away, but I felt so awful I didn’t even have it in me to try and wait any longer."

• Mano
• November 8, 2019

"Wellbutrin is a disappointment. I started taking it on August 12, 2019 because Celexa was making me more depressed. By the raving reviews, I gave it a try. It didn't take long to bring me up to "just OK," and I noticed I had motivation to get things done quickly without procrastination or avoidance. I still have that to a degree. The bad news. I also take Strattera for adult ADHD and I read that Wellbutrin can affect the efficacy. I am 99% sure it has because after three months, I'm back to having trouble processing information, being so angry and volatile and not remembering any pleasant memories. I have a reduction in empathy and increase of feeling sorry for myself. Wellbutrin is not a miracle drug, but a good anti-depressant should make you feel well enough to want to make things better, right?"

• Cmarie
• December 3, 2016

"I have been taking this medication for about 2 weeks now.. I got prescribed it in the hospital after a fallout. I tried prozac while in high school and had no luck with it. Then was prescribed Zoloft a few months ago and obviously didn't work.. considering landing myself in the hospital. Now trying Wellbutrin. Even though I have just started it I'd say that I do see some positive effects in it. I have more motivation and trying to do better for myself. But, I do have some side effects including really bad headaches, ringing in ears, insomnia, dizziness at times with nausea. I also have noticed taking Excedrin to suppress the headaches doesn't help, but make my anxiety increase. Don't take a dose late either as that just increases mood swing"

• Conqu...
• Taken for 1 to 2 years
• September 15, 2021

"It took about 2 months for me to begin to feel the effects, but it was worth it. Prior to starting Wellbutrin I tried Lexapro, Zoloft, Prozac, Cymbalta, and a fifth I can't remember, and none of them had any effect on me. After wellbutrin kicked in, my motivation returned, I was able to focus a little easier, and I reduced my stress eating. I have found that my depressive symptoms correlate strongly with my ADHD (a bad ADHD day will be a bad MDD day, and vice versa) and wellbutrin works well to combat this. The only downside is that my insomnia has become even worse, but until can find a better solution than wellbutrin, this is something I will have to put up with."

• Ellie
• January 4, 2018

"I want to start by saying that drugs have different effects on everyone so not every experience is the same. This medication has changed my life. After trying 7 different anti-depressants, then stopping, then trying again I have finally found one that works. One of my biggest problems was an inability to focus on anything and I am finally clear-minded and able to focus. I still have some problems with mood regulation but it is SO much better than before. I had some pretty bad side effects getting on Wellbutrin (but did with every drug I tried) -- extreme dizziness, nausea, vomiting and bad headaches. Side effects wore off after a week but I still get bad headaches with this med (worth it). Definitely a drug to discuss with your doctor."

• Edgem...
• Taken for 1 to 6 months
• August 21, 2016

"I was prescribed 150mg of Wellbutrin after I had attempted suicide twice. It really didn't help me. For a while I kind of just felt empty and it didn't really help my mood. To be honest, it made me worse. My anxiety was at its worse and I was still self harming and thinking about suicide. This was definitely not for me."

• JayC
• January 5, 2018

"I've only been taking it a week. I went up to 300 mg on the fourth day to help me quit smoking but I will also continue the medicine for my depression. So far, after the first day of taking this medication I've noticed I will not sleep more then 9 hours which, I could easily sleep 12 hours. When I smoke a cigarette after the first day, first couple days 1-6 so far, I do not feel any effects of the cigarette its like, I'm just filling up my lungs with smoke and not being ''rewarded'' mentally... but the craving was still slightly there. I also see people saying this medication is making them angry ... I don't know, I roll my eyes at that but everyones different."

• NJersey
• Taken for 1 to 2 years
• October 15, 2017

"I was prescribed this drug treatment in the 1997-2000 years and it caused me to end up in the ER due to spontaneous unthinkable suicide attempt by taking an overdose dose of Amblify (15 tabs!) and as soon as I swallowed it I asked myself “what did I just do?!?!? Then I didn’t know what was going to happen!?! My friend called an ambulance and I ended up in ER !?!? When Doctor asked me why I did it-“ I told him that I didn’t know?!? I had no “ thoughts of suicide and I had no idea what I was doing and that I was not going to be a danger to myself because of that!?! I had to go to Outpatient Therapy for several weeks!"

• Mj...
• Taken for 6 months to 1 year
• August 5, 2022

"I started on Wellbutrin for smoking cessation, which as only been mildly successful (I successfully quit for two weeks which was a big deal to me at the time having tried to quit 5x prior and only being able to go without smoking for max four days). It was prescribed by my PCP but when I told my psych doctor how much it helped with my depression he upped my dose. Wellbutrin is great, I've been on two SSRI meds before and I can honestly say it's the first anti-depressant that I've been on that has had a demonstrative and marked affect on my depression. I'm going to stay on it for a few years and then slowly wean off it, hopefully by then I'll've gone long enough without an episode to have next to no risk of a major relapse."

• StevenB
• August 10, 2017

"Welbutrin ruined my life. I went from 220 lbs. down to barely 100. I cannot eat. I am literally rotting away. It enlarged my prostate and now I feel like I'm carrying around a grapefruit. It also increased my libido to the point of being completely frustrating."

• Sam...
• September 8, 2016

"I'm on 100 mg of bupropion Sr twice a day. Some days I'm balanced, some days I'm full of so much energy and today zombie state. Pros? The "voices" in my head berating me every second of the day is silent. I am starting to see less hallucinations. My sex drive is up and paranoia down. Cons? Vivid dreams. Like vivid to the point of not being able to differentiate reality. Also, you always sleep late and wake up early. But you trade one major problem for a manageable one so I can deal with this. It's only been a month. Perhaps it gets better. Who knows. I am worried it may trigger another psychotic episode...may have to talk to Doctor."

• suici...
• Taken for less than 1 month
• November 3, 2015

"Took for three days. Immediately developed a craving for cigarettes. The next day I started to feel out of sorts and a stabbing pain in my heart. Stopped immediately but the other drugs I took after that made me even worse. Not recommended at all."

• Veron...
• August 19, 2021

"I believe this is an overall fantastic drug, but likely not the best fit for those with a history of chronic insomnia. I was prescribed Wellbutrin after quitting Lexapro (to avoid sexual dysfunction associated with SSRIs) and experienced a temporary decrease in my depression, but developed horrific insomnia that lasted the entire duration of my use of Wellbutrin. Because I was chronically underslept for a period of 6 months, my depression and panic disorder worsened exponentially to a critical point which resulted in me quitting Wellbutrin. Thankfully, Wellbutrin was much easier to taper off and quit than conventional SSRIs! No brain zaps or severe withdrawals. Give this drug a chance but be weary if you already battle with sleep."

• Anonymous
• Taken for 6 months to 1 year
• December 29, 2016

"Started on this med low and slow as I am sensitive to medicine. Had to increase up and no relief. Increased 3 times and still no relief. Did not do much for me but give it a chance. I took it for over six months. Many others report excellent results with it"