Wellbutrin for Major Depressive Disorder User Reviews (Page 4)

• Dan...
• Taken for less than 1 month
• March 16, 2015

"First day sucked, and most of the second day sucked... I got home from work and was sitting on the couch watching pbs thinking about how much I hate tv, when I started to feel really good about watching it.. I liked the people in it and was interested in what was being said. It was obvious it had kicked in. As far as negatives I have a slight ringing in my ears... and I'm taking 150mg XL and I can only feel it working for about 6 hours. Maybe I'll have to up my dose or take another dose later. 25yr old male. Cheers!"

• darstar
• Taken for 1 to 6 months
• July 27, 2018

"This was the only anti-depressant that I've taken that actually made me worse. Most of the others, Zoloft, Lexapro, Cymbalta, Prozac either helped a tiny bit or not at all, but never worse. Wellbutrin raised my anxiety sky high. I'm sure it may not be the case for others, but I wanted to share my experience. Good luck to anyone who does try this."

• Dan
• Taken for 1 to 6 months
• August 20, 2016

"This medication has been a godsend for me. I've been on some other antidepressants, namely Cymbalta and Buspar but I couldn't quite get my head out of the funk. Now, with Wellbutrin I feel like I'm awake and enjoying life again!"

• raven...
• December 17, 2016

"I've been prescribed several anti-depressants throughout the years, many being SSRI's and they've had little to no effect, or even the opposite effect but this medication works so well I can't even believe it. I'm so happy I was prescribed this medication for depression. I have been on it for 3 years now and my life is changed dramatically. I suffer from major depressive disorder and SAD."

• Terrie
• Taken for 1 to 2 years
• July 24, 2022

"I have taken Wellbutrin twice before and started it again. YOU NEED TO GIVE IT TIME TO WORK!!! People come in here after 3-4 days and have expected a miracle. Your body is getting used to it and will have some side effects at first. THEY GO AWAY!!!! For my first time I had to get off of it due to breastfeeding but on it I felt happier and don’t have anxiety etc with it. It was easy to get on as well. My second time I was happier, pretty much no anxiety and lost 15lbs. I don’t remember why I got off it. I had to beg my dr to put me on it and he wouldn’t so I simply found another dr who listened to me. It’s the best choice for me. I have depression and horrible anxiety. I quit two jobs due to the anxiety. This is my miracle med. we are all different though but don’t give up so easily. It works! And added bonus is some weight loss…"

• AMA
• Taken for less than 1 month
• September 21, 2019

"I took Wellbutrin for 15 days and it was a game changer.. BUT I developed an awful rash with hives all over my body. I was devastated as this has been the only medication that has actually worked for me. It took about a week for the hives to stop. I was absolutely miserable."

• Nurse
• January 11, 2020

"Made my mood better instantly. But the side effects are atrocious. Worse muscle pains ever In my back, worst abdominal pain ever. Been on it about 5 days. Not sure if I can handle side effects another week before everyone claims they go away"

• AMano
• Taken for 2 to 5 years
• March 7, 2018

"Wellbutrin is an excellent medication. I take 1/2 of a 75 mg tablet in the morning after breakfast and at 14:00. I also take 10 mg of Lexapro at 16:00. Lexapro, on its own, was providing me relief from my major depression and occasional panic attacks. However, there were some days when I felt that it was not helping. Additionally, I often felt very lethargic by the afternoon and had occasional brain fog. My psychiatrist suggesting that I complement Lexapro with Wellbutrin explaining that it is an SSRI with mild stimulating effects and does not carry the risk of weight gain. I am a slim man, so weight gain is easily noticeable for me. The combination of Lexapro and Wellbutrin has been wonderful! My depression and panic attacks are very much under control; however, there are a few manifestations throughout the year during hectic periods. I have energy throughout the day, and I am very much happier with the quality of my well-being and life."

• Kbano
• Taken for 1 to 6 months
• January 13, 2021

"I was prescribed Wellbutrin 150mg and so far it has been pretty good! I’ve been doing better mentally, and only have few side effects. Wellbutrin has made me stop biting my nails, which I’ve been doing for 14 years. It also has increased my sex drive and I can get aroused so much faster! Another thing is that I am hardly hungry, so it’s helped me lose some weight. The only negative side effect I’ve noticed is irritability. I get very snappy, and it’s over the smallest things."

• dataB...
• Taken for 10 years or more
• October 7, 2022

"150mg x2 Bupropion SR An excellent but dangerous drug. Side Effects: seizures, nausea, appetite loss, hearing damage, increased libido, increased energy, aggression or agitation. A strange medication, you lose cravings for everything but sex. No desire to eat, smoke, drink, or street drugs. However, at therapeutic levels its can cause seizures. The medication works great otherwise, I just needed to increase my anti-epileptic drug (AED). Wellbutrin acts very stimulating, so piggybacking a sedating anti-depressant or anti-anxiety med is usually a good idea. Personally, I use doxepin and (as needed) valium. It balances out Wellbutrin nicely. For the first few years, I had constant stomach pains from the medication even when taken before bed. The stomach pains went away immediately with the SR. There are studies showing Wellbutrin causing damage to hearing after decades of use. I noticed the ringing in my ears went away (after 20 years or so) but my hearing was now worse."

• Istrian
• Taken for less than 1 month
• December 22, 2022

"Was taking this for only 2 weeks due to intolerable side effects: high blood pressure that was causing nose bleeding, fast heart rate, insomnia, easily angered, crying spells, and it didn't really make me feel any better."

• Depre...
• Taken for 1 to 6 months
• March 3, 2021

"From the past 10 years I’ve been fighting depression and anxiety which leads to ongoing panic attacks that lasts a week or two. Escitalopram was working really well but my erections became impossible (I’m a 31 year old male). My doctor stopped that and put me on Wellbutrin 150XL. After just the first dose, I noticed an odd shift in my perception of reality. After a month, I was off caffeine, cigarettes and urbanol (used to manage initial anxiety). I made an effort with regard to my career and managed to land the job of my dream. After month 4, I was put on the full 300XL. My brain feels healed. My pathways that were broken for years are now lighting up in my brain. A lot of people think this drug is a strong stimulant but I’ve taken Ritalin and it’s WB is no where close! Also, since I’ve given up caffeine and nicotine, the net effect is less brain stimulation. After 6 months on this dosage, I plan to wean off with the help of my doctor"

• KateD
• Taken for less than 1 month
• August 6, 2018

"I want to preface this with a note: we all react differently to medicine; my experience is not indicative of Wellbutrin itself, nor is it premonitory of how you will react to the medication. My psychiatrist prescribed 150mg of Wellbutrin at the beginning of July. He added it to my Prozac 40mg to help with some major depression I've been having as of late. When I began the drug, I took it in the morning because it is supposed to give you energy. I immediately felt like a zombie! I could not function -- everything was in slo-mo. I walked as though I was drunk, I forgot words while speaking, I was forgetful in the midst of doing a task. It got really bad when I was driving so slow and swerving into the curb. I dropped from 150mg to 100mg. It did not a difference. That day, my mother took my to the hospital. I was given fluids and immediately stopped. I've been off of it about a week and a half and I am feeling so much better."

• Alexa...
• Taken for 2 to 5 years
• August 23, 2015

"Wellbutrin is probably the best antidepressant on the US market. It's best to start at > 75 MG a day to make sure you can tolerate it; there are many who this medicine does nothing for or causes anxiety or other health problems. Regardless of what they say; do check your liver and kidneys; it is more non-toxic than a lot of drugs but it does take a toll on your body over time. For me, nothing as of yet."

• Name
• Taken for 6 months to 1 year
• June 8, 2019

"Even after 8 months of taking Wellbutrin 300 mg daily, Wellbutrin increased my anxiety from a 7 to a 9. Even though I'm not bipolar, I felt mean and irritable on it. It helped reduce physical symptoms of depression such as sleep and body weakness problems but it gave me way too much energy during the day. Now, the drug company is researching adding a cough suppressant to it. No thanks."

• NJMan
• January 31, 2020

"I was on Paxil 20mg for 16 years to treat MDD. It was extremely successful at treating the depression. I still had some anxiety and the side effects of weight gain and loss of interest in sex were apparent. The Paxil pooped out on me. The psych nurse practitioner advised Wellbutrin to get away from the weight gain and sexual side effects. I've been on 75mg once per day for nearly 8 weeks now and honestly I'm still unsure. I've lost 15lbs and my interest in sex has increased a little. I've had really bad agitation especially in the first few weeks that made me want to scream. It has eased up since then but not completely gone. Just as I think I've turned the corner I slip back a little. My dose is low as that is how my Psych nurse wants it. She has suggested switching to 200mg of the SL version to address the anxiety I'm still having but I fear the agitation returning like it was or worse. I couldn't say to someone - choose Wellbutrin."

• MWH
• August 10, 2022

"Oh boy do I have a lot to say about this medication! I started taking this med and didn’t feel much for a few weeks. One day I woke up and my depression vanished! My concentration improved as well and my ADHD was non existent! As the day went on I started to feel extremely euphoric though, almost to the point where I thought I was manic. After a couple days that subsided and this medication was amazing! My ADHD and depression pretty much vanished Until one day I came home from church and had a grand mal seizure. I never had a seizure in my life until then. I spoke with my psychiatrist and my mother who is also a licensed mental health professional and they both confirmed that Wellbutrin CAN induce seizures in anybody. Please be careful because doctors will not tell you this side effect. I was so sad because this was the only medication that seemed to work and I had to get off to prevent another seizure. This is a great med but be careful!"

• Mid30...
• Taken for less than 1 month
• December 7, 2016

"This medicine has improved my depression dramatically. I feel calm, am able to focus and get things done, but not with the manic rush of another medicine I used to take. Hopefully will help me lose weight over time."

• wanna...
• Taken for less than 1 month
• November 28, 2015

"I've been on Bupropion 150 SR once a day for 8 days. So far I'm only feeling side effects; dry mouth, sweating, jaw clenching. It has not lifted my depression or energized me. Celexa and Zoloft used to work for me but then slowly stopped working. I'll try to stick it out for a few more days. I was really hoping that this med would work for me. I feel that I may be drug-resistant to A/Ds. I also take 1 mg Klonopin to sleep and to lower anxiety."

• Somer
• Taken for 2 to 5 years
• July 14, 2021

"I started taking Wellbutrin 150mg SR about 3 years ago. It didn't help my depression very much. I finally started seeing a psychologist that told me it has to be taken 12 hours apart. So I was taking it at 8am and sometimes wouldn't take it till 11 pm or I'd forget a dose. I was finally switched to 300 mg 1x along with buspar for anxiety & a mood stabilizer. The mood stabilizer is the best medication I've ever taken. It's helped me 100%. With the Wellbutrin XL I started out with tons of energy and no appetite but after awhile that stopped. So if you're taking the SR and it's not working I'd switch to the SL once a day. Once I switched it started working."

• Halcyon
• Taken for 1 to 2 years
• September 3, 2019

"Probably the most effective medicine I took for my suicidal ideation and depression but unfortunately I had almost all the adverse reactions. I didn't want to give up because it was the first time I felt better after so long but my doctor felt it was necessary for me to not use it anymore. Sometimes I consider requesting to be put on it again but I just haven't found anything that really works properly for me and I've just become super desperate at this point."

• Iwant...
• Taken for less than 1 month
• July 5, 2016

"I have been on Wellbutrin 75mg x 2 a day for a week. I have CFS and MDD, SAD, as well as mild OSA. My sleep doctor suggested Wellbutrin because of its stimulating effects after I asked about Provigil or Nuvigil for my extreme fatigue and depression. The first four days I felt like I drank 20 cups of coffee. Jittery, gnashing my teeth, tensed up muscles, hard time sleeping, while still depressed. Not a good combination. After four days the stimulant effect suddenly went away and was replaced by the worst sleepiness I've ever felt. An hour after taking the pills I practically fall asleep. Drowsy and sleepy all day to the point of not being able to function at my job. Not sure if I can continue Wellbutrin for much longer."

• jaime
• Taken for 5 to 10 years
• March 30, 2024

"Wellbutrin improves concentration and clarity of mind. It reduces anxiety and improves sleep when you don't get enough but is not a sleeping pill. Low sexual side effects but may increase erectile dysfunction. Not sure about it."

• Nicole
• Taken for 6 months to 1 year
• May 6, 2019

"This worked amazingly for my mood and really helped me get through a very dark time but this medication unfortunately caused me to develop severe cystic acne on my face. It was after a couple of months on the medication that the acne started develop and it only got worse from then. As soon as I stopped the medication, the acne disappeared almost immediately but I am left with a lot of scarring. I tried countless creams and tablets for the spots but nothing worked therefore coming of wellbutrin was the only option which was a shame because this pill was a life saver for me."

• Sta
• Taken for 1 to 6 months
• April 17, 2021

"I started taking this medication both for my depression as well as for weight loss. I also take Paxil. For the positives, I have noticed increased motivation, increased libido, and decreased appetite. I haven't lost much weight yet but I have PCOS so I know that's going to take time. As for side effects, I sometimes experience drowsiness within an hour or two of each SR dose. I also notice that I become very cold sensitive and need to bundle up to stay warm, but this goes away as each dose wears off. I have occasional premature heartbeats and they seem to be happening more often on Wellbutrin. I've also noticed my dreams are more vivid."