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Wellbutrin for Depression User Reviews (Page 5)

Wellbutrin has an average rating of 6.9 out of 10 from a total of 505 reviews for the treatment of Depression. 61% of reviewers reported a positive experience, while 21% reported a negative experience.

Reviews for Wellbutrin

  • 555Ca...
  • September 30, 2013

"I've been on Wellbutrin in combination with Prozac for almost a year now. When I began Wellbutrin, for the first couple of months I felt like I was on speed. I would constantly shake and my heart rate was pretty fast. For the first couple of months, I experienced very large mood swings that led to me making very irrational decisions. Despite this, I continued taking it, and after about 3 months I wasn't so shaky or moody anymore. When I began Wellbutrin I weighed about 115 pounds, and I lost 15 pounds over the course of 2 months on Wellbutrin, and have been stabilized at 100 ever since. Wellbutrin has caused me to be more energetic, happy, and friendly. I definitely recommend it."

8 / 10
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  • Tay
  • Taken for 1 to 6 months
  • June 9, 2015

"I spent a lot of time reading reviews, and it took me a while to even start the medication, but I finally said, 'Screw it, I'll try it.' After reading the reviews, most people said they felt better almost right away. So, after 2 months when I still wasn't feeling great, I started to get nervous. Then, 3 months approached and I started crying less and less, and I actually got excited to do things again, and by 4 months, I feel great! I'm so glad I stuck with it. If your depression is bad, this really can take up to 3 months, but don't give up! I did have to take Buspar with it because I'm just naturally an anxious person, and that helped with my anxiety and to balance it out. I now take 100mg of bupropion in the morning and 100mg in the afternoon, and it's just enough!"

8 / 10
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  • Zoe...
  • Taken for less than 1 month
  • December 9, 2013

"I am 23 and have had major problems with depression since I was 14. I've tried Lexapro and Zoloft...nothing. This is my fourth day on Wellbutrin. I told my family that it may just be the placebo effect but I already feel better. Before...I'd get depressed or angry over small things and stay that way for hours, if not for the whole day. Now...I stop myself before I start, which is a tool I did not have before. It's still way too early, yet it may all be in my head, but here's to hoping this works for me! I have a 2-year-old, fiance, and live with my parents...life has been crappy for a long, long, long time. It's time for me to be happy!"

9 / 10
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Frequently asked questions

  • Maestro
  • Taken for 6 months to 1 year
  • November 15, 2019

"I started taking wellbutrin to stop smoking but I also take effexor for depression. I replaced the effexor with Wellbutrin and took it with no ill effects and also was able to stop smoking after 55 years with the habit. Hooray for Wellbutrin."

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  • Laura...
  • Taken for 1 to 6 months
  • December 10, 2012

"I took Wellbutrin at first to quit smoking. This was last year. It really did help me quit smoking, and that was great. I have to say, DO NOT DRINK ON WELLBUTRIN because it made me black out and I had huge problems from this. After my bad experience drinking on Wellbutrin, I stopped taking it. After reading these reviews again, I have decided to get back on it, and this time around I won't have a problem seeing as I quit drinking completely. I have been in denial for a long time, but I do suffer from severe depression and weight problems, and I am praying that this time around I can stick to it and turn my life around. Thanks everyone for sharing your stories; they are very inspiring!"

7 / 10
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Are you taking this medicine?

  • someone
  • Taken for less than 1 month
  • June 17, 2023

"I started bupropion 75 mg and was on it for 10 days. The first days I was agitated and hypervigilant, had problems with driving as everything attracted my attention, and felt a bit more active. I became careless and a bit arrogant. My empathy and people-pleasing behaviors lowered. I could socialize not feeling inferior. Slowly the medicine lost effect. The next 10 days were bupropion ER 150 mg. It gave me grave depression, I feel like I am in a cage, extreme depression, and I feel people are all monsters. I still have empathy but no joy, no happiness, nothing. I can study and my brain fog is gone. I can focus If I eat something. Now I am on 300 mg bupropion ER. Still very depressed. No joy. My kidneys are starting to hurt, and I have some breathing problems and nasal dripping problems. Super aware of my surroundings studying is easy. I have lost joy and I sleep all the time. I have a dull headache. I feel like if I continue I will have a mental episode."

1 / 10
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  • deelo...
  • Taken for less than 1 month
  • August 12, 2013

"Taking 300mg Wellbutrin XR, and it is already working after only one week. I have good energy, and do not feel like hiding in my room anymore. It gives me a floating feeling a little bit, but absolutely tolerable compared to the horrible depression I was experiencing. I am bipolar, and have experienced no mania at all. I am grateful for this med!"

10 / 10
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More FAQ

  • Luvnh...
  • Taken for less than 1 month
  • August 29, 2018

"I have generalized anxiety and just worry so much all the time. This medication has helped me with my anxiety. It has kept my mind from constantly running and thinking too much (about bad stuff). It has also given me a little pep in my step and has made me a lot nicer to be around, especially for my kids and husband. I have had some side effects but it did take about 2 weeks for it to finally start working. I am pleased with this med so far. No libido problems either. So I am happy."

10 / 10
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  • Sjom
  • Taken for 1 to 6 months
  • August 23, 2012

"Bupropion has restored my very far-gone faith in the entire concept of medicine for depression. It's not an acutely noticeable effect. I am not jumping for joy or smiling like an idiot, but I am not depressed anymore. I still have kind of a sad life thanks to my mental health problems, but I no longer feel like I need to kill myself in the near future. I don't cry, and my anxiety has become less severe. Prior to bupropion, I had been on a ridiculously long list of other antidepressant medications (Including but not limited to: Fluoxetine, Citalopram, Venlafaxine, Mirtazapine) and benzodiazepines for anxiety (like, 4 different ones). These did NOTHING. But bupropion did. It's kind of amazing. I recommend it highly."

8 / 10
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  • Anonymous
  • January 19, 2012

"I'd never thought about depression until I happened to read a psychology case study. I read about a person that could have been myself. I wasn't feeling sad or suicidal, but I had no energy, self-control, and the only way to get me to do something was negative motivation. I had gotten to the point where I rarely bathed, missed work as often as I possibly could without getting fired, couldn't even make myself go to the store when I needed something. When I started taking the 150 mg XL, I started to have good days during the second week, and after being on the 300 mg for a couple of months now, I feel like a new person. So much more energy, motivation, etc."

10 / 10
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  • Monk
  • Taken for less than 1 month
  • September 14, 2019

"I like my GP but I think they were a bit hasty to prescribe the Wellbutrin for me before I started therapy, which begins in 5 days. This was supposed to be an interim measure to help me cope with a severe depression from my last child leaving home. I am a dad and it really has been terrible. I have always been highly sensitive. I have been on this for 4 days and I will not take another. This stuff is dangerous if not correctly prescribed. I think it can lead to severe psychosis. That is what happened to me last night. It took every ounce of willpower I have to pull myself out of an episode which I can't even describe. Scared the living daylights out of me. USE WITH EXTREME CAUTION!"

1 / 10
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  • Nellie
  • Taken for 10 years or more
  • September 12, 2017

"Best antidepressant I've ever taken, bar none. I have been taking Wellbutrin for over 10 years, and even though I've had the dosage adjusted over time, it has worked wonders. The reasons I like it are no weight gain, doesn't zap my energy, and helps me complete tasks. The only downside I have found is that it will keep me awake at night if I take it after 10 am. I do take the generic version."

10 / 10
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  • jttw
  • November 18, 2014

"I've been on Wellbutrin (my first antidepressant/anxiety med) 150mg once a day for about 7 weeks. It's good for those who emotionally eat. I've already lost 15 lbs because I don't have that feeling of hopelessness & it gives me no appetite. I have to force myself to eat for nutritional reasons. On the downside, my insomnia is out of control & affecting many parts of my life. I also have experienced several itching fits after about a month & needed Benadryl to get some relief. Otherwise, I would give it a 10."

8 / 10
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  • Pr23
  • November 4, 2019

"I’ve been on Wellbutrin for about almost 2 weeks now, for depression I’m giving it a seven out of 10 because I used to cry every day when I woke up , drove to work, drove home and before bed. Now I don’t cry at all, in fact I actually feel peaceful. Is this how normal people feel? I used to drink coffee multiple times a day, and now I don’t even crave it. I also used to smoke marijuana here and there to stop crying at night. And I haven’t had the urge. Anyways, I’m worried about the whole anxious thing, sometimes I find myself not focused @ work and sometimes feel overwhelmed. But I’m going through a terrible break up so I don’t know if it’s the depression or the pill. I’ve also lost a lot of weight which I’m not mad about. I don’t crave junk or carbs. I don’t feel sad any more. I guess I would say I feel kind of numb/ peaceful. I’d rather feel numb than the horrible painful depressing feeling I used to feel every day, I would feel worthless. Let’s hope the anxiety goes down!"

7 / 10
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  • Sarah...
  • September 18, 2017

"Amazing, it has absolutely changed my life, from the first day I started it. My smoking has decreased drastically. I am highly motivated to do everything I need to do in a day. I am thinking clear, I haven't had a single nap since taking it! A life changing pill for me!!"

10 / 10
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  • Anonymous
  • Taken for 1 to 2 years
  • February 12, 2015

"My depression was primarily characterized by hopelessness and lack of motivation, and within weeks of starting Wellbutrin, I experienced dramatic changes in my mood and mindset. I often forget that I even take Wellbutrin because it has given me no side effects and has only made me feel the way I was always supposed to feel. This drug is definitely worth a try; even if it doesn't work so effectively for everyone, the potential for a negative experience is very low compared to that of other antidepressants."

10 / 10
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  • hopeful
  • February 17, 2014

"Day 6 and I'm up at 2 am. Maybe the energy is kicking in, I don't know. I suffer from bipolar, anxiety, panic attacks, depression. I usually feel a little manic all the time, but the 2nd day taking this medicine, a calmness came over me. I'm a pack a day smoker, but haven't had or wanted a cigarette from that 2nd day. I'm taking 75 mg twice a day, but I think I need to just take it in the morning. I don't feel all energetic but I haven't been taking a nap in the afternoon like usual. And tonight I can't fall asleep... and I take 100 mg of trazodone to fall asleep. Also I haven't been on Amazon and eBay wanting to buy everything I see. I'll see how it goes day by day but I'm very hopeful! By the way... if you are bipolar, DO NOT TAKE LEXAPRO!"

8 / 10
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  • britt...
  • July 14, 2009

"Love it, Love it, Love it. I was on it 5 years ago and could tell within 2 days such a major change in my mood and motivation. I went off it when I became pregnant with baby #1 - 5 years later I felt I needed it again, I didn't feel 'depressed' but I knew I could feel better. I went back on Wellbutrin 150mg once a day and again by day 2 I was feeling amazing - totally can focus better and just love life again."

10 / 10
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  • Still...
  • Taken for 1 to 6 months
  • February 16, 2020

"I took this for a little over a month for depression. This medicine worked very well at improving my mood and I felt much happier on it. Unfortunately for me, something in at least the generic version of this caused me to break out in an itchy hive-like rash. The rash would tend to break out anywhere heat was generated so for me it was concentrated on my inner thighs. It was so itchy! Nothing OTC worked to make the rash go away. I stopped the medicine and slept with ice packs to ease the itch. It still took weeks after stopping the medicine for the rash/itch to go away. Kinda disappointing because I can tell that it works, I just can't tolerate the itchy rash side affect. It works extremely well for my mom and she doesn't have any side affect so it just depends on the person I guess."

8 / 10
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  • fluffy
  • Taken for less than 1 month
  • January 24, 2020

"I was put on Wellbutrin for depression and had violent, psychotic episodes out of nowhere. Was delusional, convinced that people in my life were out to get me, were spies, that my pet kitten was evil. When people tried to calm me, I saw them as menacing and would physically lash out. I went to my doctor and was told that I was lying about this... I'd never had psychosis before or after the medication. Only on it."

1 / 10
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  • Manav
  • Taken for 1 to 2 years
  • December 8, 2016

"I got depression and anxiety after one summer of abusing ecstasy and acid. This was 2003. For quite a while I didn't medicate as I was still in denial. After about 2 years of suffering, I started taking Lexapro. It didn't do much. I began to get severe headaches. After 2 years, I switched to Zoloft. Kept waiting for things to get better but they just got worse. I began to put on weight. To feel better, I was binge eating junk food. I became sickly bloated and had terrible OCD. Eventually, out of desperation, I switched doctors 2 years ago and he prescribed Wellbutrin XL. Thank God. The fog began to clear up, I felt optimistic, less anxious, lost weight. I am almost 80% better. Living a normal life. Wellbutrin saved my life."

10 / 10
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  • natur...
  • April 4, 2008

"I have tried many many other medications for my bipolar depression, none of which were effective. Wellbutrin improved my mood significantly and within the first two weeks. (They tell you it takes 4-6 for most meds to begin working.) Don't suffer any longer, try this one. P.S. No weight changes!"

8 / 10
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150 Report
  • Nandor
  • Taken for 1 to 2 years
  • September 29, 2019

"In summer 2017, I had a depressive episode, worsened by Cymbalta. I was suicidal with no emotions or appetite. I told my doc and started Wellbutrin 300mg. I was wary because the last 2 meds I took didn’t help. 2 weeks later, after Cymbalta’s horrific withdrawal ended, my emotions returned. I could enjoy things again. By week 4, I was happy for the 1st time in years. I could cry again (a weird thing to be happy about, but it felt good to feel again). I had mild side effects: a dry mouth and shaky hands. I think how I felt the following year is how healthy people feel. I’ve never felt better. In fall 2018, things went downhill. I was having panic attacks and dark depressing thoughts. I thought it was stress, so I reduced my workload. It didn’t work. I was depressed/anxious daily until now because I was too nervous to tell anyone. Last week my doc prescribed an extra 150mg (450mg total). Nothing yet, but the higher dose may help. If I can edit this, I’ll add my experiences on 450mg"

9 / 10
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  • Itsok...
  • November 27, 2015

"I have not noticed an effect on my emotions. I experience them like normal but they're less intense and not as long-lasting. My appetite is not as much as before. The biggest difference for me is that when I wake up, I'm not exhausted. I am finally waking up with energy! I am so thankful for that. My dreams are incredible now and very vivid. I still wake up in the middle of the night sometimes from a noise, but even if that happens, I still feel well-rested in the morning. My sex drive has increased a lot, but it had been a year of feeling complete apathy towards sex so maybe I'm just back to normal but not used to it. I feel good and this actually has decreased my anxiety! Wish I would have found this years ago."

8 / 10
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  • Anonymous
  • Taken for 10 years or more
  • June 16, 2012

"I have taken this medication for approximately 10 years. I have discontinued use 3 times, and my depression resumed each time. I believe many side effects and negative experiences could be avoided if doctors would start patients out with a smaller dose. It has been my experience that when I start with 300 mg I have migraines, nausea, dizziness, and itching. I do not have this issue if I start off at 50 mg and gradually increase over 3 months to 300 mg. This medication helps me more than any other and does not make me gain weight. It also seems to slightly help with my adult ADHD, anxiety, OCD, PMS, and chronic pain."

10 / 10
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119 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.