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Wellbutrin for Depression User Reviews (Page 4)

Wellbutrin has an average rating of 6.9 out of 10 from a total of 505 reviews for the treatment of Depression. 61% of reviewers reported a positive experience, while 21% reported a negative experience.

Reviews for Wellbutrin

  • hsoj
  • April 24, 2016

"Probably saved my life. This is the first antidepressant I tried as I was scared of some of the nasty side effects of the SSRIs (sexual, weight gain, tiredness). I was on Wellbutrin XL 150 mg for 1-2 months and then have been on 300 mg XL for 3 months now. Getting on it was a little strange, as I had some side effects of anxiety at first, but actually have not had a panic attack since starting. Just know that it doesn't really help with anxiety/OCD symptoms (but I've been going to therapy for that). Really made me motivated to get work done (never been the case for me) without that craziness feeling from Adderall. Very consistently good mood and makes me want to be alive. Also increased sex drive + motivation for exercise is a plus."

8 / 10
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  • Anonymous
  • Taken for 6 months to 1 year
  • July 1, 2017

"This drug has saved my life! I have struggled with methamphetamine addiction for about 4 years now. The hardest part about quitting was the extreme depression and suicidal thoughts. They always caused me to relapse. My physician prescribed Wellbutrin and it has worked like a miracle. I have been clean for over half a year and feel like I have my old life back! My relationships are healing and my family feels like they have their son/brother back. I am back in college and passing my classes! I don't attribute all that to the drug. Counseling and AA were extremely helpful but I know it was Wellbutrin that got me through the horrible depression to the other side. Only upfront side effects I had were jitteriness and dry mouth."

9 / 10
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  • Claire
  • Taken for less than 1 month
  • May 1, 2021

"I’m that patient that smokes you know what... My doctor knows. This time around being 20 now and taking this pill again, I’m on day 4 or 5 and my appetite is absolutely gone even when elevated. But I think I’m feeling more balanced out overall, but when I have my anxiety moments, they are very intense. Too soon to tell if I could recommend it, but it has interacted fine with maryJ past 4-ish days:"

6 / 10
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Frequently asked questions

  • Shy...
  • February 5, 2021

"I started taking 100mg of Wellbutrin 2 months ago. I was prescribed it for ADHD but I also suffer from severe depression. The first four days of this drug were absolutely awful, I cried and felt an extreme hopelessness. After the second week the sadness was fading but I felt numb, the only positive thing is that it has decreased my irritability HEAVILY like I used to snap at so many small things and now I am unbothered but this has been replaced with sensitivity and getting emotional/crying easily. Also has helped with my sex drive. It hasn’t helped for my ADHD, I also no longer have an appetite. Two days ago I was bumped up to 300mg a day and the first day taking it I went back into the same despair I felt, but the suicidal thoughts were worse this time but luckily my boyfriend was there. I’m not sure if this is worth taking in the long run but I’d rather be more emotional then have the irritability come back. Wishing everyone suffering from depression lots of love:)"

6 / 10
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  • berp
  • Taken for 1 to 6 months
  • January 11, 2020

"I started Wellbutrin 4 months ago at age 40. It was my first time using medication, although I've battled depression (and a subsequent eating disorder) since I was a child. A few years ago, anxiety started tormenting me. I couldn't live like this anymore. My GP started me on 150 mg, but after 6 weeks with no difference, upped it to 450. Finally, I realized the change: I was calmer, no longer judgmental towards myself, my unsatisfactory life situation, and my body. The anxiety and depression were gone. I treated myself with self-compassion and acceptance - all firsts for me! However, I also didn't care about exercising, and I've been an athlete and hiker all my life, so my energy level had evidently decreased. These past 4 months have been a lovely, gentle reprieve from the perfectionism and pressure I've put on myself my whole life. I've learned CBT and DBT therapies and am in recovery from my eating disorder. But now I want to feel energetic again and to wean myself off of Wellbutrin. I'm very grateful for it though!"

8 / 10
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Are you taking this medicine?

  • McLovin
  • Taken for 1 to 6 months
  • May 20, 2014

"I tried a couple of different SSRIs and found that most of them gave me bad side effects and made me feel empty, so when I heard about Wellbutrin, I asked my doctor if I could try it. It's one of the few that also doesn't give you a decreased sex drive. I was a bit scared after hearing some of the negative reviews, but this medication works wonders for me. I have had no side effects at all, and within a day, I started feeling better. I would recommend this to anyone who hasn't had luck with SSRIs."

10 / 10
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  • momsn...
  • Taken for less than 1 month
  • November 15, 2012

"This is the most amazing medication for depression! I have used it in the past, and I am so glad to start back on it again. I have had so many bad things happen, that it is time for some good. I am grateful for the way it helps me see the bright side of life, instead of living so unhappily and feeling hopeless. If you have ever thought of suicide, please don't do it. I know this medicine helped me from doing it in my past, it's wonderful. Problems are temporary."

10 / 10
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152 Report

More FAQ

  • judon...
  • Taken for 1 to 6 months
  • June 11, 2022

"I've had moderate depression and some anxiety most of my life. It manifests mostly in the forms of low energy, worrying, irritability, and avoidance. Dishes piling up, laundry not getting done, car interior a mess, etc. I tried two SSRI's (Lexapro & Zoloft) before switching to Wellbutrin, which is Dopamine Reuptake Inhibitor. Dopamine! That was the answer. It wasn't a serotonin problem, it was a dopamine one! The SSRI's worked ok, but I was always tired and foggy. I gave each 6 months. I eased off the SSRI and eased into the Wellbutrin. I only take 150mg at the moment. I'm almost 4 months in, and I can't believe the improvement. I bound out of bed in the morning and start getting stuff done. My attitude is positive, excited, eager for the day and being alive. I can't believe it. All those years with the background hum of depression, even if mild at times, made me think feeling that way was normal. It wasn't! This turned out to be the perfect fit for me."

10 / 10
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  • smw
  • Taken for 5 to 10 years
  • July 20, 2012

"I'm 33 years old. I've been on this medication for 6 years. My mood, temper, and life in general are so much better. I went several years with depression that came on with postpartum. In a state of denial about my condition and not wanting to be labeled, I would not seek treatment. I wish I would have done so much sooner. I cannot say enough about Wellbutrin; it has changed my life. I deal with stress, death, and everyday life of raising two teenagers now, which I firmly believe I could not have done without it. I have found you can be happy and would encourage people to get the mental help they need because medications like this one are life-changing. I can also add side effects have not been an issue for me at all."

10 / 10
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  • HHano
  • March 1, 2020

"I was on Celexa for a couple of years but I flatlined and felt like a zombie. My psychiatrist switched me over to Wellbutrin. I was nervous to take it because it works with different neurotransmitters. Celexa works with serotonin while Wellbutrin with dopamine. It felt like my eyes were being pulled up by magnets, it was hard to look forward and I was dizzy. This subsided after a few weeks. My anxiety became way worse. Everyday I felt like all of my nerves were exposed. I overreacted to everything and caused a lot of fights. Then the suicidal thoughts. I've struggled with these thoughts when I was off of meds, so to be flooded with them again was scary. These thoughts were invasive and more intense than I've ever experienced. Luckily I was able to realize that it was just the medication, so I switched to Zoloft. Please be careful if you take Wellbutrin. If you get those dark thoughts, remember it is not you, it's the meds."

2 / 10
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  • Lost...
  • May 3, 2009

"It has helped me a lot with my depression and anger problems. For the first time in 9 years, I don't wake up mad at the world with homicidal thoughts. The side effects that I experienced are dizziness when I stand up too fast and my loss of appetite (not a bad thing). I was overweight anyway. I've only been on it for 2 weeks and have lost 13 pounds, but it makes me feel so much better about myself."

10 / 10
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  • Nigel...
  • Taken for 2 to 5 years
  • June 28, 2024

"For years I was on SSRIs and they almost destroyed my life. This drug saved it. I feel like myself without that awful hazy effect that SSRIs produce. It helps a lot with anxiety and my PTSD. It also helped me quit smoking."

10 / 10
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  • JIC
  • Taken for 1 to 6 months
  • November 19, 2016

"I tried for 2 years after a major life change to get my life back. All the SNRIs and SSRIs gave me the worst side effects, and I became more depressed, dizzy, had migraines, and felt suicidal. This wasn't me, and every doctor wrote me off as being a bad patient. I was ready to throw in the towel and tried a low dose of Wellbutrin, and OMG. 2 months later, I was completely myself, and 6 months later, I'm medication-free. Don't give up, keep trying. I thought my life was over, and I was a difficult patient. Don't let message boards or doctors rule your life. If something isn't working, don't stay on it!"

9 / 10
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  • graph...
  • Taken for 1 to 6 months
  • June 16, 2015

"I've been on Prozac for about 20 years, and it's been a lot of help, but at age 68, I found myself wanting to nap a lot more and my motivation decreasing. I switched to Wellbutrin, and once the therapeutic dose was established, I began to feel better within a week or two. I feel more energetic and yet more composed and at ease. I'm very pleased with this drug, not the least because my sex life has returned. I think my life would have been different if I'd started it 20 years ago."

10 / 10
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  • Connor...
  • January 5, 2014

"I've been taking bupropion 75mg twice a day for the past 6 weeks and I feel like I'm finally back to the real me. I'm 18 and have been dealing with depression, but this medication helped me tremendously. I was originally on Paxil, but due to sexual side effects, I switched to this and it restored my sex drive. I also have a little bit of anxiety, but this medication cleared that up as well. The first week was hard. I experienced heart palpitations, very anxious, ridiculous energy, and I was easily agitated. After the first week, those side effects slowly diminished and now I don't have them at all. That is the only reason I didn't give this medicine a 10. It saved my life. I HIGHLY recommend this to any who doesn't want sexual side effects."

9 / 10
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  • pearl
  • July 31, 2008

"I've been taking this medication for a couple of years. I no longer obsess over things and am no longer as depressed as I used to be. They seem to keep me in balance with my emotions. I would recommend this to anyone with depression and also compulsive behavior."

9 / 10
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179 Report
  • Anonymous
  • Taken for 6 months to 1 year
  • January 4, 2017

"Started Wellbutrin XL at 150 mg once a day to treat depression and anxiety, although was more concerned about depression. The first week I was on it, I was absolutely miserable. I did not sleep or eat at all, and was crying constantly, and I think it definitely worsened my depression. However, I called my doctor and had my dose lowered to 75 mg and not extended release, and I immediately felt better. I have been on that dosage for about 6 months now, and I feel amazing. I am able to control my emotions so much better, and I rarely have meltdowns (I used to have a complete meltdown anytime anything negative happened to me). I definitely plan on staying on Wellbutrin. Would just recommend you make sure you are on the right dose."

8 / 10
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  • eliza
  • June 3, 2016

"Shortly after my 20th birthday, I developed what I later found out was major depression. After starting counseling, I reluctantly started taking Wellbutrin, and within a few days, I was a noticeably different person than I had been the past 6 months. I began to act like my old self again, gaining confidence, and for the most part, being free from all of my depression episodes that had occurred daily. The biggest side effects that I experienced were weight loss/loss of appetite and trouble falling asleep at night, but after about two weeks, those both went away. I've now been taking 300mg daily for about six weeks and feel great! I'd encourage you to give this medication a try because it can potentially really change your life."

9 / 10
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  • Kufan
  • Taken for less than 1 month
  • November 9, 2015

"I'm a 24-year-old male. I started taking Wellbutrin a week ago. I did 150mg for 3 days, then 2x a day now. I noticed a change by the 3rd day. My coworkers said I was more energetic and a nicer person. I'm on day 7 now and I am thinking more clearly than I have in a long time. I don't get frustrated so easily, I can fall asleep a lot faster because I'm not worrying all the time, and I get up in the morning with ease. I really like this antidepressant. It's the first one that has actually worked for me."

9 / 10
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  • Anonymous
  • Taken for 1 to 2 years
  • October 17, 2018

"I’ve been on Wellbutrin for a little over a year, and honestly it’s been life-changing. I’ve been able to go farther in my weekly talk therapy and get to issues that were blocked in the past because of depression and anxiety. I’ve gone further in my career and found a lot of daily comfort from feeling generally better and able to get through depressed times. I think I finally see an end point to therapy (it’s been nine years). I lost a few pounds and initially had a burst of sexual energy that has sadly dissipated. Now I’m back to normal sex drive, which is so much better than an ill-fated Lexapro trial years ago that prevented me from trying other antidepressants for years. I’m so very glad and grateful I found bupropion."

10 / 10
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  • toni
  • Taken for 2 to 5 years
  • February 12, 2020

"Started Wellbutrin 150 three years ago for depression, worked great, lost about 15 pounds in 6 months. Here's the downside, HAIR-LOSS. I have loss 1/3 of my hair, and enough was enough. Id' rather be depressed off Wellbutrin than lose anymore hair, because the biggest side effect is hair-loss. Two week after getting off Wellbutrin, new hair everywear. I'll take back my weight and some depression cause I want my hair back."

4 / 10
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67 Report
  • Anonymous
  • June 30, 2010

"I was tired all the time. I have been to Iraq and back, and the way I felt was just the way I thought I should feel. I was lazy sometimes, would put things off, irritated, and got upset quickly. For years and years, I just thought that was me. I was a major drinker and smoker, couldn't ever get enough sleep, and had no motivation to get out of bed. Again, I thought that was me. I started to have anxiety after my wife had a miscarriage. Then we got pregnant again, and things really started to get out of control. Wellbutrin saved me. I quit drinking and smoking! I'm motivated, love being a dad, work is great! Slight sexual side effects."

8 / 10
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158 Report
  • Liz
  • June 30, 2020

"I have anxiety, depression ADHD and so far on wellbutrin I have had stomach problems. Also I have lost 7 pounds while on this medication. Most of the time I don’t feel like doing anything through out the day."

4 / 10
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  • Piano...
  • Taken for 1 to 6 months
  • May 12, 2013

"I am a 53-year-old prostate cancer survivor (radical prostatectomy and adjuvant radiation treatment) with depression/anxiety. I started on 150mg of Wellbutrin 6 months ago. Recently, I started having major depression/anxiety feelings about work. I am now taking 150mg twice a day, and I feel great. I cannot believe the difference in my mood from dismal depression to optimism. I also quit smoking and drinking. I've been doing the South Beach diet with moderate exercise (30-40 minutes walking on a treadmill) and have lost 20 pounds, but I was about 100 pounds overweight so I have a long way to go. I am just a few days into the 150mg twice a day regimen, but the results with respect to mood change have been remarkable."

9 / 10
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  • HBano
  • Taken for 2 to 5 years
  • October 23, 2019

"I have been on Wellbutrin 300 mg once a day for about 2 years now. This medication has changed my life. It did cause me to have severe anxiety at first, but I am now on a medication for the anxiety and the Wellbutrin has knocked out the depression almost 100%. I am doing the things that I love again and am so much nicer and calmer to the people around me. I went off of it recently for a week and a half due to some insurance issues and I am back to crying daily, laying in bed wanting to do nothing, and sleeping my weekends away. I recommend trying Wellbutrin and seeing what it can do for you!"

10 / 10
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69 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.