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Bupropion for Sexual Dysfunction, SSRI Induced User Reviews (Page 4)

Brand names: Wellbutrin XL, Wellbutrin SR, Aplenzin, Forfivo XL Budeprion Budeprion SR

Bupropion has an average rating of 6.8 out of 10 from a total of 98 reviews for the off-label treatment of Sexual Dysfunction, SSRI Induced. 55% of reviewers reported a positive experience, while 21% reported a negative experience.

Reviews for Bupropion

  • Anonymous
  • Taken for 1 to 6 months
  • April 7, 2024

"I added bupropion to treat PPD, and I began to notice an increase in my sexual desires. This medication was added in addition to Cymbalta. Since starting Cymbalta, I became virtually asexual. I had no desire for sex, found attempts at intimacy by my husband off-putting, and generally had to prepare myself to enjoy sex (mentally and never pressured). I was on bupropion for about 1 month, and my sex drive returned. Then, I stopped due to concerns over my son's health and breastfeeding, and my sex drive tanked again. After bupropion was ruled out as the cause of his issues, I restarted and sure enough, my sex drive returned."

9 / 10
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  • 2x52x6
  • Taken for 1 to 6 months
  • September 19, 2022

"50 year old male. I was put on Strattera for ADHD and it helped with that concern, but in turn it caused my orgasms to be completely lack luster. My drive stayed normal (high for me at my age), no problems getting/staying erect, but my orgasms and ejaculations were sub par. I talked to my NP about this and she said "I'm going to send a prescription over for Wellbutrin. You don't have to take it, but I think you'll like it" Well, I definitely like it. It's made orgasms as good or better than they used to be and my ejaculations seem to have more volume and certainly more power. The only 2 unusual things now are I have A LOT of pre-ejaculate as I approach climax and after I actually climax my penis, just my penis (shaft) aches harshly for 30 seconds to a minute. It's very odd, but I've become accustom to it. It beats the bland finish Strattera caused me."

9 / 10
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  • Portu...
  • Taken for 6 months to 1 year
  • July 22, 2021

"Firstly I had a moderate depression with loss of sexual drive, then I take Zoloft plus bupropion, while I take both my sexual drive is increased a bit but I had a very hard time to cum. My therapist removed Zoloft from equation and I am only bupropion now. Now my sex drive has gone away, it is very hard to maintain erection. My sex life is ruined... It destroyed my mood in consequence. I'm in a process to stopping to take bupropion."

1 / 10
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Frequently asked questions

  • 69...
  • Taken for 1 to 6 months
  • February 16, 2022

"I have suffered from anorgasmia for over 10 years now and my urologist did not offer an explanation. I achieved an erection and orgasm but there is no pleasure at ejaculation. This situation upset me, because I was a sexually active man for my entire life and orgasms were intense. About 4 months ago, the doctor prescribed Lexapro to treat anxiety. Within 10 days of taking it, achieving an erection and orgasm was nearly impossible. My doctor switched me to Bupropion (200 mg/day). Within 4 days of taking it, my orgasms returned with a vengeance. I had never experienced such an intense orgasm in over 10 years - it was explosive and traveled from my groin to my feet! I also noticed that I was more horny. The intense orgasms continued each time I ejaculated, which was on average once per day. However, after maybe 3-4 weeks of taking Bupropion, the orgasm intensity began to wane. Even after ejaculating less, maybe every other day, the intense orgasm was never as good."

8 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • December 27, 2019

"I was on 20mg Celexa for anxiety and depression and it was helping apart from the notorious sexual side effects. Being fed up with this I thought I'd give Wellbutrin a try. The Wellbutrin helped the sexual dysfunction, however ,it increased my anxiety. The voice in my head was racing, I was sweating a lot, and I could barely get off the couch. I have since switched back to celexa ,however, I'm still feeling the effects of the Wellbutrin 2 months later and my celexa isn't working as effectively now."

2 / 10
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Are you taking this medicine?

  • abid...
  • Taken for less than 1 month
  • November 24, 2023

"I am taking bupropion XL 150. It helped in improving my mood and focus. It had some side effects like nausea and tingling in ears, but two of the other side effects were good for me. I feel less horny and have reduced cravings to smoke."

8 / 10
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  • SCARL...
  • January 24, 2016

"Just met the most amazing man that is taking this medication to stop smoking. He's been nervous about sexual side effects as a result of using this. Good news - since getting together, even via text or Skype we discovered he doesn't need it.....just talking turns him on. Touching me will eliminate and and all need for any type of medication without doubt!! Sorry burproin but we're OK...actually fantastic"

2 / 10
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  • Toby...
  • Taken for 1 to 6 months
  • September 16, 2021

"Terrible Drug, it’s making me agitated, I’m having frequent mood swings, increase in depression and quite frankly has done nothing for my Sexual Dysfunction, I was so hyped to start this line of treatment as SD induced by Clomipramine was taking its toll on me, very very disappointed I’ll be going off it in a few days, but I’m glad it’s working well for others but it just isn’t for me"

1 / 10
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  • Paul
  • Taken for 1 to 6 months
  • March 20, 2022

"I experienced a slight orgasmic delay with sertraline. I was started on Bupropion XL. After 3 wks on the 300mg dose, this resolved and I actually started experiencing “cluster” orgasms (usually 2-4 orgasms in rapid succession with about 5-10 seconds between)."

10 / 10
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  • Bup...
  • Taken for 1 to 6 months
  • March 13, 2024

"I took it for 1 and a half months, my erections became more frequent and easier to get and maintain. I managed to have much more pleasurable sexual relations with my partner and I managed to be very satisfied with sex, even under the influence of alcohol I was able to obtain and maintain erections without any difficulty."

7 / 10
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  • Anon
  • Taken for less than 1 month
  • December 9, 2021

"I'm about 1 month into Bupropion, and my experience is a bit different than what seems like most on these comments. I took Paxil many years ago so recall the sexual difficulties or an SSRI, but I found that Bupropion also has adverse sexual side effects. Over the past month I have not been stimulated or aroused or interested in masturbation. Additionally, my manhood has been more flaccid than it is usually. When I did have sex once last week, I had an uncontrollable premature ejaculation, which I've never really had before. Then, after that, I wasn't able to get erect again, and remained flaccid, even though I've had multiple consecutive erections and ejaculations with the same person before (up to 5 times in a row at times) AND I had taken 1mg of Sidenafil! This time, I was basically one and done. I will keep taking it for some of the energy and motivation it provides, and the feelings of positivity, but I hope to get off of it soon–or when I have a more regular sexual partner."

6 / 10
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  • csand
  • Taken for less than 1 month
  • June 5, 2023

"During week 3 of using bupropion, started getting what the internet said were "thunderclap" headaches. The moment I orgasm BAM! instant migraine from hell. I'm thinking it's raising my blood pressure. I will give it 3 more weeks before I toss it out. I need to enjoy my delicious orgasms again. Haven't noticed much change in the depression department."

2 / 10
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  • I...
  • Taken for less than 1 month
  • February 14, 2017

"I am a 35-year-old woman, and I've always had a pretty healthy sex drive...but this is insane. I have been on this drug for three days, and I can orgasm at the drop of a hat. Best day ever."

10 / 10
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76 Report
  • Grays...
  • Taken for 1 to 6 months
  • December 24, 2015

"Used to be a wild man in bed. I've been on it for 4 months and have completely lost all interest in sex."

1 / 10
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77 Report
  • Bdap
  • Taken for 1 to 6 months
  • July 6, 2019

"Experience less sensation and inability to climax"

8 / 10
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46 Report
  • Anonymous
  • November 13, 2015

"Full erections and orgasms again. Prozac killed my libido and my sexual functions, but no side effects with Wellbutrin."

10 / 10
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61 Report
  • CHAgirl
  • Taken for 1 to 6 months
  • December 8, 2015

"I was on Paxil, which killed my sex drive. My sex drive on Wellbutrin is insane. My husband is a very happy man."

10 / 10
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53 Report
  • Harmony
  • Taken for less than 1 month
  • March 18, 2020

"I've been on these pills bupropion for three week I they really helped me ...(I had sexual problems caused by SSRI meds "

10 / 10
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29 Report
  • Anonymous
  • April 27, 2010

Wellbutrin (bupropion) "Has always worked for me. Zero sexual side effects."

9 / 10
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63 Report
  • Ron
  • August 23, 2017

"this medicine has decreased my my libido. I'm just 24 years old and cannot reach orgasm after taking this med. horrible."

1 / 10
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36 Report
  • Uknow...
  • Taken for less than 1 month
  • January 17, 2016

"I'm a female and man this drug has made me orgasim like 3 times in one night I love it !"

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37 Report
  • Sleep...
  • Taken for less than 1 month
  • January 17, 2020

"I was prescribed this to counteract the sexual side effects of Fluoxetine (low desire). This did seem to increase my desire but orgasms were mild. Also caused me sleep issues, insomnia, restlessness."

6 / 10
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17 Report
  • Anonymous
  • March 5, 2017

"Check out the article entitled " The antidepressant drug best for sex". Phycology Today"

9 / 10
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19 Report
  • Anonymous
  • Taken for 2 to 5 years
  • March 28, 2018

"It did not affect libido at first, but after 2 or 3 years I have little interest. I'm happy without it and do not seek it. I'm married and 35."

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12 Report
  • Yuri
  • Taken for 1 to 6 months
  • November 1, 2021

"Improved my sex life considerably. Stronger orgasms, I can’t explain, almost had spontaneous orgasms, now it’s stable. Very good medication."

10 / 10
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6 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.