Bupropion for Sexual Dysfunction, SSRI Induced User Reviews (Page 3)

• Ano...
• Taken for 6 months to 1 year
• July 15, 2015

"I been on Celexa in the past. Totally kill my libido, nothing work down there, get soft most of the time. Doc chance to Wellbutrin HCL XL 150, it really helps increase my libido. Never get soft, I guess get the job done for me. Plus, keep me motivated."

• Anonymous
• Taken for less than 1 month
• February 11, 2021

"I'm on the second day of taking this drug. I am taking it because of my 5-year lack of libido issue and numb feelings because of other pills. I have borderline, so I felt different from day one of taking this pill. I hope these side effects will accommodate over time. First, I noticed hard headaches, and second, it is giving me euphoria, sudden mood swings, I have my natural emotions back. I will update later on."

• MrQ...
• Taken for 1 to 2 years
• January 9, 2017

"I have been taking Wellbutrin for about 18 months. At first, my libido came flooding back as it does when I am no longer feeling the pangs of deep depression. It eventually settled into normal levels, but my main problem is my endurance! I have always been able to go the distance more or less, but these days I climax in 60 seconds every time! It doesn't matter if we just had sex 5 minutes ago... 60 seconds and I spill the beans! I am a 37-year-old male, so maybe time is catching up with me? Idk..."

• Smi...
• Taken for 5 to 10 years
• August 3, 2020

"The arthritis doctor put me on Cymbalta for pain, but after a week or so I couldn't have an orgasm, erections were okay but couldn't get off. The wife tried to no avail. I talked to the doctor and he advised me to check with my urologist, who checked me out and found nothing wrong. So I went online for a sex therapist that would take insurance as most only take payment at office visits. The therapist recommended this but didn't tell me if it worked or not. Wellbutrin for 8 years now, and it's awesome. It took 3 weeks before I felt any improvement, but the kick was amazing! Sensation has returned and was great. I have stopped Cymbalta after back surgery but still use Wellbutrin 200XL daily, just using a shower handheld unit is great also. LOL, the therapist was happy that it worked well as she said some men really have good results as women, but it doesn't do so well for others."

• I...
• Taken for 1 to 6 months
• November 25, 2017

"A bit concerned over some of the comments. I took bupropion in the past for smoking cessation and am now on it again for depression. However, I work in the mental health field and specifically requested it for the least likely to affect my sex drive. However, prescribers should not be prescribing it to people with anxiety issues, as it's known to increase anxiety. I know when I requested it, I was grilled to ensure that I didn't. If your prescriber knew you had anxiety and prescribed this, I would find a new prescriber."

• Ano...
• Taken for 1 to 6 months
• February 8, 2025

"I'd never been able to orgasm despite having a high sex drive and masturbating a lot. I've been on multiple SSRIs and SNRIs for years. I went on this for PMDD and depression. Within 2 weeks of starting it, I had a powerful multiple orgasm. Unfortunately, I adjusted my dose, and the being able to orgasm only lasted a month. I had to take 60 mg duloxetine and 150 mg bupropion to have this effect."

• Hus...
• November 21, 2017

"My husband is 49, and I am 36, and since he has taken this medication now for 5 years, we have no sex life! Makes me mad! What other medication can he be put on to help bump it up to even 1 day a week? I thought about having him stop taking it, but the only problem is with that. He is horrible and very mean without this medication. Can someone help?"

• Cha...
• Taken for less than 1 month
• July 29, 2021

"Male, 34. I started taking bupropion 2 weeks ago (150 mg per day) as requested by my doctor. Now I can no longer get a real hard erection or have an orgasm. I'm well endowed, so I figured it took more blood flow to achieve the result I was wanting, so I took a 100 mg Viagra tablet I got from a friend. After about 30 minutes, I could achieve a full erection but still could not have an orgasm. It was like all the sensation in my penis was gone. It's very frustrating to say the least, as it does in fact increase your libido. As of today, I will no longer be taking this medication. Hope things get back to normal quickly."

• Dru...
• Taken for 1 to 6 months
• February 14, 2022

"Bupropion has been a godsend. I’m a 65-year-old male who was on paroxetine, and because of that, I had given up on sex. Paroxetine had gotten rid of my ability to orgasm or ejaculate. My doctor put me on bupropion XL 150 mg, and what a change. My mood is stable, and depression has remained under control. But my sex life has come back with a vengeance. Orgasms are insanely intense and long-lasting. I am in a constant state of semi-arousal. I am beginning 300 mg daily, so that will be interesting. Emotionally, I’m not sacrificing anything but gaining back my sex life. A win-win."

• Joh...
• Taken for 1 to 6 months
• September 1, 2022

"I was on bupropion for 2 months. I switched to Zoloft, which I think was a mistake. I don't think I gave the bupropion long enough of a chance. The last week that I took it, I noticed I was 'happier,' but I had already begun weaning myself off it. I am putting in a request to my doctor to go back on it. As for sexual-related stuff, I will say it made me last longer, and my 'ejaculate' was about 4x more than the normal. No joke, it just kept going and would shoot far like in the adult films. Crazy stuff, and I want to get back to that. I long for it."

• Kar...
• Taken for 1 to 6 months
• July 9, 2022

"Oh goodness, where do I start? I was on fluoxetine for depression for 3-ish months, and it absolutely tanked my sex drive. Like, for 2 entire years. I maybe had sex 6 times within that timeframe. I stopped taking fluoxetine and didn’t take anything else in case my sex drive came back. It didn’t at all. I almost lost all hope, to be honest. 3 weeks on 150 mg/day Wellbutrin-bam. It was like a light switch went off. Better than it was even before taking fluoxetine years ago. I feel like a monster, lol. I was certainly skeptical because there’s no *real* scientific evidence that it should help with sexual issues in women, and my doctor expressed that as well. But it was the only medication that my insurance would cover. Dang, am I glad that I’ve been prescribed Wellbutrin. I’ve heard that it helps certain people, and others it doesn’t. It’s worth a shot, though. I haven’t really had any adverse effects yet."

• Bup...
• Taken for 1 to 2 years
• April 29, 2022

"For the first few weeks, I experienced increased sex drive, I lost a few pounds, but if I took it too late in the day, I had trouble sleeping. After the initial effects wore off, I noticed my orgasms have gotten really strong, some so powerful it almost hurts. I’ve never felt anything like it. That’s been a side effect that hasn’t subsided, but I am definitely not complaining."

• AJP...
• Taken for 1 to 6 months
• December 29, 2022

"This actually gave me anorgasmia despite being used to improve sexual function. It improved libido and ED somewhat, but absolutely zero feeling from orgasm. It is not a typical response, but beware, it can happen."

• Mat...
• Taken for less than 1 month
• September 13, 2016

"I used Wellbutrin for a month to start stopping smoking. I used it as you should use Zyban (first week, one pill in the morning, then the next two months, two pills a day with a minimum of 8 hours in between, best long before evening). After 2 weeks of use, I lost a lot of libido and nearly all ability to get fully erect. Now I stopped it by eating one per day for a week. Since two days, I've fully stopped and am still waiting on the libido and erectile ability I had before that idea of stopping smoking and eating Wellbutrin...."

• Anonymous
• October 5, 2020

"I lasted 3 days on this. I had been taking Lexapro for 1 year at 10 mg and was up to 20 mg. A few months after that my libido had entirely gone, I gained 20 lbs, and wasn't able to focus. My doctor switched me to Wellbutrin. Huge mistake. Day 1 I was full of anger followed by bouts of anxiety and crying. I was sent home from work and put on leave for my mental instability. Day 2 I was extremely irritable and crying every few hours. Day 3 was the deal breaker. I was home alone and randomly started crying. Crying turned into a major panic attack, and from there I was thrown into a state of hysteria. I had to call my mom to come over, and it took her 3 hours to calm me down. I immediately stopped taking it. I'm 28 with 2 small kids. I couldn't afford to let them see me that way and honestly was terrified of what had happened on the 3rd day. It seems to either work really great for some and really bad for others. I highly suggest taking precautions when starting this medication."

• Anonymous
• Taken for 1 to 6 months
• April 7, 2024

"I added bupropion to treat PPD, and I began to notice an increase in my sexual desires. This medication was added in addition to Cymbalta. Since starting Cymbalta, I became virtually asexual. I had no desire for sex, found attempts at intimacy by my husband off-putting, and generally had to prepare myself to enjoy sex (mentally and never pressured). I was on bupropion for about 1 month, and my sex drive returned. Then, I stopped due to concerns over my son's health and breastfeeding, and my sex drive tanked again. After bupropion was ruled out as the cause of his issues, I restarted and sure enough, my sex drive returned."

• Wor...
• Taken for 1 to 6 months
• May 30, 2023

"Started on 75 mg twice a day. Felt mood improvement in about a week. The only major side effect I have experienced is extreme horniness. Thoughts of explosive sex go through my mind constantly, even in my dreams. I’m in a much better mood and significantly less irritable, but the constant desire for sex is disturbing."

• Hik...
• January 9, 2018

"I have been taking antidepressant and anxiety medication for 30+ years. You name it, and I've taken it. I have been diagnosed by several doctors and psychiatrists as bipolar and manic depressive. After 23 years, I finally got tired of all the meds and went cold turkey and stopped taking them all. My doctor put me on Wellbutrin/bupropion to calm my nerves and depressed moods... (SSRIs) were causing me sexual side effects. Just after 1 month, it helped with my depression, but it caused erectile dysfunction. Then I had to go on the expensive Cialis medication to help with my ED... BTW... Bupropion didn't have any effect on my libido."

• Eme...
• December 14, 2016

"I added this to my dosage of sertraline because I was always tired and foggy, and sex had become really difficult. It initially helped for these issues, but it worsened my anxiety and caused constant fluttering heart. I went ahead and tapered up to the dose the doc told me to start with, and suddenly I began developing horrible hives all over my body. It was easily the worst itching I have ever experienced. My hands and feet blew up like balloons, and I couldn't walk as a result for over a week. I stopped taking the bupropion the day after my symptoms appeared, but they also stuck around for over a week."

• Anonymous
• Taken for less than 1 month
• January 6, 2023

"I am taking 300 mg, and by the second day, it has shown a lot of results. Definitely easy to get aroused again, but stimulation is still reduced in quality for me. Still makes everything easier, and perhaps it will continue to increase in function. As for its antidepressant effect, I do think it makes daily life things more enjoyable when I'm not caught up in thoughts. It also may be contributing to better focus for me due to it blocking the reuptake of norepinephrine. The main side effect, which goes away in 2 weeks for me, was a dry mouth. I would really recommend trying this drug in general. Definitely isn't an unwelcome addition to my daily meds."

• abi...
• Taken for less than 1 month
• November 24, 2023

"I am taking bupropion XL 150. It helped in improving my mood and focus. It had some side effects like nausea and tingling in ears, but two of the other side effects were good for me. I feel less horny and have reduced cravings to smoke."

• Ray...
• Taken for 1 to 2 years
• March 6, 2018

"Helps counter Effexor XR 75 mg sexual issues. I have OCD, so it agitates that. I take 450 mg XL, but may drop it to 300 mg. It helps if you are tired. It can raise blood pressure. I also take 25 mg of Naltrexone, and that greatly helps in the sexual side effect department."

• Por...
• Taken for 6 months to 1 year
• July 22, 2021

"Firstly, I had moderate depression with loss of sexual drive. Then I took Zoloft plus bupropion. While I took both, my sexual drive increased a bit, but I had a very hard time to cum. My therapist removed Zoloft from the equation, and I am only on bupropion now. Now my sex drive has gone away, it is very hard to maintain an erection. My sex life is ruined. It destroyed my mood in consequence. I'm in the process of stopping taking bupropion."

• 2x5...
• Taken for 1 to 6 months
• September 19, 2022

"50-year-old male. I was put on Strattera for ADHD, and it helped with that concern, but in turn, it caused my orgasms to be completely lackluster. My drive stayed normal (high for me at my age), no problems getting/staying erect, but my orgasms and ejaculations were subpar. I talked to my NP about this, and she said, 'I'm going to send a prescription over for Wellbutrin. You don't have to take it, but I think you'll like it.' Well, I definitely like it. It's made orgasms as good or better than they used to be, and my ejaculations seem to have more volume and certainly more power. The only 2 unusual things now are I have A LOT of pre-ejaculate as I approach climax, and after I actually climax, my penis, just my penis (shaft), aches harshly for 30 seconds to a minute. It's very odd, but I've become accustomed to it. It beats the bland finish Strattera caused me."

• 69...
• Taken for 1 to 6 months
• February 16, 2022

"I have suffered from anorgasmia for over 10 years now, and my urologist did not offer an explanation. I achieved an erection and orgasm, but there is no pleasure at ejaculation. This situation upset me because I was a sexually active man for my entire life, and orgasms were intense. About 4 months ago, the doctor prescribed Lexapro to treat anxiety. Within 10 days of taking it, achieving an erection and orgasm was nearly impossible. My doctor switched me to Bupropion (200 mg/day). Within 4 days of taking it, my orgasms returned with a vengeance. I had never experienced such an intense orgasm in over 10 years - it was explosive and traveled from my groin to my feet! I also noticed that I was more horny. The intense orgasms continued each time I ejaculated, which was on average once per day. However, after maybe 3-4 weeks of taking Bupropion, the orgasm intensity began to wane. Even after ejaculating less, maybe every other day, the intense orgasm was never as good."