Bupropion for Sexual Dysfunction, SSRI Induced User Reviews (Page 2)

• boniver
• July 22, 2011

"After being on Lexapro for 6 months, I had lost all desire for sex and it felt like a chore that sometimes could not be completed. Did I mention I am male, and my wife is amazing? Anyway, I felt missing out on one of life's greatest pleasures, and the intimacy missing in my marriage was no longer tolerable. I spoke to my doctor and started Bupropion. After about 3 weeks, I began having sexual desires that had been missing. Sexual focus returned to my whole body in a lose-your-breath, heart-skip-a-beat sort of way. I may someday give up the Lexapro (20), but I am not sure I am ready, and outside of the sexual side effect, I have to give it credit for doing wonders for me."

• Bano
• Taken for less than 1 month
• May 5, 2020

"I’ve been on bupropion for depression and ADHD symptoms, but besides that, it has really improved my sex drive. I used to be on Prozac, and that totally had ruined it. I’m really satisfied with the changes it’s given me. I have had no weight gain, acne, nor any types of side effects."

• No Nick
• Taken for less than 1 month
• February 2, 2013

"Male 59, in excellent health, no prior problems. Started taking bupropion 3 weeks ago as adjunct to citalopram. Seems to have improved my mood, but for the past 2 weeks, I have not been able to achieve orgasm. Erections are fine, just now cannot get to the happy ending. I am stopping this medicine."

• Peter...
• Taken for 1 to 6 months
• April 28, 2015

"Took the medication for a while. Worked well for depression and overall well-being, but I did notice it killed my ability to get a solid erection and sex drive was reduced. This trickled into performance anxiety. Trying to figure out how to overcome that now has made things worse for me."

• lovin...
• September 25, 2011

Wellbutrin (bupropion) "I was put on 150 mg of Wellbutrin twice a day. It has completely helped my depression and amped up my sex life. Things could not be better. Our sex life has always been amazing but without the depression in the way it's even better."

• Druskee
• Taken for 1 to 6 months
• September 4, 2013

"I have tried several anti-depressants, and this is the only one that has not taken away my libido or ability to reach orgasm. No libido can cause depression, the whole point of taking these medications. I have not mixed bupropion with an SSRI, so I can't give an opinion on the two together and how they interact on sexual issues or lack of. So for those wondering (men especially), this medication will give you energy and NOT affect your sex life negatively."

• Anonymous
• October 23, 2010

Wellbutrin (bupropion) "I was put on 100 mg Wellbutrin for PMDD issues and stayed on it for about three years. I ended up having many side effects, such as added anxiety, horrible headaches, and constipation. I also lost some weight. However, the mood swings stopped, and I have to say sex was never better. It added to my sexual response for sure, and I really miss that part. If not for the constipation and heart flutters, I would have stayed with it."

• Ninde...
• Taken for 6 months to 1 year
• August 10, 2016

"I've been on Prozac for just over a year now, and one of the side effects for me was decreased libido (it was almost extinct before the Prozac), and my psychiatrist thought adding this would help. I was excited because of the supposed weight loss and appetite suppression that goes along with this medication. Unfortunately, it did not help me weight-wise, but my libido went from 0 to 100! My husband couldn't keep up! I'd never, and I mean NEVER, been that ready to go in my whole life. After a few weeks, the effects wore down to more like a 20, so I still have that desire, just not 6 times a day (seriously). I called it my women's Viagra, lol! I also managed to quit smoking last year while on this too. Yay!"

• Switc...
• Taken for 1 to 2 years
• May 31, 2017

"I have been on anti-depressants/anxiety medications for the last year now and have been on 3-4 (Lexapro, Celexa, Trintellix, and Wellbutrin) to try to find one that doesn't give me sexual side effects. Lexapro made me feel the best but has the worst sexual side effects. Wellbutrin was my last hope, and sadly, it hasn't worked for me at all!! I see so many posts on here that say it is magical, which is great for many of you but so hard to believe. I still want to have sex but can't reach an orgasm the conventional way. I have lost all sexual sensation, and that is so depressing because I never had issues in the past. Like another person remarked, I would rather deal with my anxiety than deal with these side effects!"

• Ava
• Taken for 1 to 6 months
• December 27, 2020

"I was on 10mg/day of Prozac for over 10 years and it didn’t seem to be working anymore. I got depressed recently and the psychopharmacologist added 125mg of Wellbutrin (alternating dose of 100mg and 150mg) and I’ve tapered down the Prozac to 5mg/day. While I’m glad my energy has increased, my sex drive has actually gotten too strong, especially since the wellbutrin has made it so I can’t orgasm. It’s extremely frustrating and I find it embarrassing to talk about with the doctor. It’s nice to have my sex drive back after years of it being low, but horrible not to be able to orgasm. It’s making me irritable."

• 22Fem...
• Taken for 1 to 6 months
• August 19, 2016

"Have found it impossible to orgasm on this medication, and I will be in the middle of sex and suddenly loose all drive. It helps with everything else, but I'm in my prime. I miss the crazy sex I used to have."

• allis...
• Taken for 1 to 6 months
• November 29, 2016

"36, female. I have been on Lexapro 10 mg since late March '16. I'm very active... running, hiking, yoga, and still managed to put on 10 lbs in 6 months, and the sexual side effects suck! Pdoc added Wellbutrin XL 150 mg/day to try to help with SSRI-induced SE. I have been on the WB for 2 days now, and I could not believe that it already brought back much of my libido, as well as sensation and faster orgasm. I hope this keeps up-if so, the WB/SSRI combo may save us all! Good luck! UPDATE (3 mo use): Wellbutrin XL is still doing wonders for my depression. It still helps with sexual side effects from the Lexapro, but not as much as the first week mentioned above. Def helping but not eliminating. I'll still take it though b/c I def need some serotonin too."

• Harley
• Taken for 1 to 6 months
• March 31, 2023

"Please do not take this medicine. I took this because of my depression and I took it only for a week maybe a month at the longest until I found out I was pregnant with my son. In that short amount of time, it caused my vagina to be dry and I don’t like sex because it is uncomfortable and it feels like my skin is ripping apart. and I can't orgasm anymore. It has been like 5 years since I took it and I still have these problems and I don’t think there is a way to fix it. I hate myself for this. I cry all the time."

• I...
• Taken for 1 to 6 months
• November 25, 2017

"A bit concerned over some of the comments. I took buproprion in the past for smoking cessation and am now on it again for depression. However I work in the mental health field and specifically requested it for the least likely to affect my sex drive. However, prescribers should not be prescribing it to people with anxiety issues as it's known to increase anxiety. I know when I requested it, I was grilled to ensure that I didn't. If your prescriber knew you had anxiety and prescribed this, I would find a new prescriber."

• SIA
• Taken for 1 to 2 years
• August 19, 2018

"My doctor switch me to bupropion 300mg because Zoloft caused me sexual dysfunction when I was changed to it at first it was great I had orgasms again but, after being on it for over a year I have lost interest in sex and when I have sex I couldn't have an orgasm so needless to say I'm no longer taking this medication."

• AJHJR
• Taken for 5 to 10 years
• December 13, 2021

"I have read some of the comments from people here stating that there is no clinical evidence showing proof that Welbutrin helps with sexual issue. This is not an accurate statement. My wife takes this medication and it indeed works. Clayton, A.H. et al. “A Placebo-Controlled Trial of Bupropion SR as an Antidote for Selective Serotonin Reuptake Inhibitor-Induced Sexual Dysfunction,” Journal of Clinical Psychiatry (2004) 65:62."

• Anonymous
• Taken for less than 1 month
• February 11, 2021

"I'm second day taking this drug. I am taking it because of my 5 year lack of libido issue and numb feelings because of other pills. I have borderline so I felt different from day one taking this pill. I hope this side effects will accomodate over time. First I noticed hard headaches and second, it is giving me euphoria, sudden mood swings, I have my natural emotions back, I will update later on"

• Wowee...
• Taken for 1 to 2 years
• June 6, 2016

"Male 30. I've been taking it to control add and depression and as a pleasant side effect it allows me to go 2-3 times a night if she'll let me. I have not been this horny since I was 13 . Thank you magic chemists for making this drug."

• Weird...
• Taken for 2 to 5 years
• September 15, 2016

"I love this pill! I call it the happy pill ! 32f. After the first few months of nightmares - I've become the happiest person alive. After reading all the comments. - my sex drive seems to have increased but reaching orgasms has been hard. It does gives me energy. I quit cigs. And it possibly lowered my blood pressure. I can't comment on the weight part cause I'm already chubby and love food. I've been way more nice and friendly to people too."

• Bob
• Taken for 1 to 6 months
• March 10, 2019

"Love that it helped take the edge off my depression. But I’m 35 and have a horrible time now getting hard (erectile dysfunction) - I’m stopping it today to see if in a few days, it’s better. Needless to say, I hadn’t had a problem before taking it."

• Anonymous
• Taken for 1 to 6 months
• April 27, 2023

"I really, really like bupropion. I’ve been on all the main SSRIs over the years. My most recent expedition was with Zoloft, which was TERRIBLE. Truly the worst experience I’ve ever had. I had every single symptom and it exacerbated all my anxiety. I kept hoping it would help but it never did. I could also barely orgasm. At some point I got frustrated at feeling numb and sexually dysfunctional and got a script for bupropion since it worked well for my brother. Oh my. Things changed. I’ve tapered off the Zoloft, stayed in the bupropion and feel better than I have in a year. My sex drive is crazy - my boyfriend is overwhelmed. Very grateful I found something that works for me."

• Young...
• Taken for 1 to 6 months
• November 22, 2017

"I was prescribed this drug for my depression and I've been in it now for about 6 months. It's definitely made me a happier person over all. I feel great until I try to have sex... I'm 24 years old and the only significant change in my life recently has been this drug. At first I thought it was me, but I'm convinced it's the drug. I used to be a stud in bed but now it's nearly impossible for me to get hard. I'm going to talk to my doc about getting off this pill before it ruins my relationship."

• Bullet
• November 24, 2017

"I’ve been taking Zoloft for three months and after one month it was damn near impossible to orgasim. I still had the desire for sex and would reach the peak before the orgasm, however, the orgasm would never come! It was so frustrating that I gave up on even trying. I told my doctor and she added the lowest dose of Wellbutrin. I’ve been taking it for four days and I’m proud to say I had an orgasm within two minutes the other night. I also feel a lot better and a lot more calm. I also like how I’m able to focus on a task like I use to pre medication. With the Zoloft it made me so lazy and even took away my good anxiety. I have a high metabolism and felt the effects of Zoloft and Wellbutrin within the same day. Which isn’t typical."

• Husband
• November 21, 2017

"My husband is 49 and I am 36 and since he has taken this med now for 5 yrs we have no sex life! Makes me mad! What other med can he be put on to help bump it up to even 1 day a week?!! I thought about having him stop taking it but the only problem is with that.. He is horrible and very mean without this med. CAN SOMEONE HELP?"

• Anonimo
• Taken for 6 months to 1 year
• July 15, 2015

"i been on celexa on the past totally kill my libido nothing work down there get soft mostly time doc chance to welbutrim hcl xl 150 it really help increase my libido never get soft l guess get the job done for me plus keep me motivated"