Auvelity for Major Depressive Disorder User Reviews (Page 2)

• Brian
• Taken for less than 1 month
• February 26, 2023

"I'm about 3 weeks in, and I've noticed a decrease in depression symptoms, particularly low energy levels and loss of motivation. Some minor side effects the first few days, but all is good now. Hoping to continue to see symptom improvement with this medication!"

• MsSnu...
• Taken for less than 1 month
• March 14, 2024

"I stumbled serendipitously on the combo of Delsym and Wellbutrin after a Covid infection a few weeks ago and was prescribed Auvelity after observing I felt much better with that DIY version. Over the last 3 weeks, I have felt better than I have felt in the last 10 years. I've tried many antidepressants and they must work to some extent (because I felt worse when I’ve tried to stop them) but I was still very tearful, ruminative, irritable, hopeless... like Eeyore, but with anxiety."

• Amy
• Taken for 1 to 6 months
• July 29, 2023

"I've been taking Auvelity for 5 months, and I can honestly say I have not felt this good in many years. I have had depression for 40 years. I know I'm still depressed to some degree, but the heaviness is gone. I can find joy easier. I'm rarely suicidal. I felt very weird, dissociated for about the first month. It was like I was walking beside myself and watching my life - I felt separate from the depression. It's very hard to explain. I'm just so glad I stuck with it. I would definitely recommend it. I had been taking Wellbutrin for years."

• rosie
• Taken for 1 to 6 months
• December 22, 2023

"This medication has given me my life back. I have been on many antidepressants and have finally found one that has been a game-changer for me. I have prayed for many years to recover from the depression."

• Lisa
• Taken for less than 1 month
• July 25, 2024

"My adult son had tried numerous prescriptions for help with depression, anxiety, and OCD. Auvelity has quieted his OCD (it's still there, but it's not as strong) and has immensely helped his depression. He has started appreciating music and art again, noticing things of beauty. He is hopeful for his future. He usually only takes one tablet per day in the morning."

• Rubbe...
• Taken for 1 to 6 months
• March 28, 2023

"I tried several different drugs that didn’t work very well for me and was starting to get frustrated. Auvelity began working within one week and has helped me IMMENSELY. I am finally able to get through the day without crying. My panic attacks have lessened. I am excited about my future (can’t remember the last time that happened). It is very expensive, but there is a voucher to get it for $10! Search Auvelity $10 voucher/coupon and show it to your pharmacist."

• ALP
• Taken for 1 to 6 months
• April 12, 2024

"Right before being prescribed Auvelity, I was probably at my lowest. I saw no hope, no purpose, no point in continuing to fight what felt like a never-ending uphill battle. My psychiatrist switched me from Wellbutrin to Auvelity, and I didn’t feel any change for about a week. I was really discouraged, as I had read that change is usually felt within a few days on this med. Just after the 1-week mark, things changed. I felt lighter, things felt easier. Day by day, my entire view on life started changing. I wasn’t terrified of the future, I wasn’t dreading each and every day, I wasn’t hoping I would be a victim of some great accident to end my suffering. It sounds dramatic and it is, but this med has done so much for me. I am just over a month in and I literally would not be here if I had not started this medication. My only downside is the cost and access of this medication, due to insurance not covering this and the manufacturer coupon not working without it. Fingers crossed."

• Dgad
• Taken for 1 to 6 months
• June 3, 2024

"Follow-up from the first review. Been on Auvelity for 2 months now. It helped tremendously for depression but not so much for my anxiety. About a month ago, my doctor put me on Buspirone along with Auvelity. My anxiety is now almost totally gone, and my depression remains in remission. I am very grateful for both medications."

• Rough
• Taken for 1 to 6 months
• November 22, 2023

"It has been amazing. I felt better just 2 days later. My psychiatrist suggested a placebo effect, but the change has been too significant for that. My brain is quiet and I feel at peace. I've been on it for about 2 months."

• Meshal
• Taken for less than 1 month
• April 5, 2023

"I am on week two now. I would say this medication works fast. I was so depressed, but it changed the way I think and feel. No side effects for me, but just on the first day, I felt nauseous. I like it for real. I will keep you updated, guys."

• klb
• Taken for 1 to 6 months
• April 14, 2023

"Going to say this is the best medicine I have taken in a long time. Been on them all, and all stopped working as I'm very resistant to medicine. I'm very hopeful that Auvelity will be a game changer for me."

• birdmom
• Taken for 6 months to 1 year
• September 6, 2023

"I have taken antidepressants my entire adult life, since they first became available (Elavil), with varying degrees of success. Finally, about 11 years ago, I was dosed correctly with a cocktail of five drugs, and I did well for almost 10 years. Then last fall, I noticed that the depression seemed to be creeping back in, for no apparent reason. I was afraid to have my meds changed because I was afraid I would get even worse if they were changed, but finally, I became suicidal and knew something had to be done. After a frank talk with my prescriber, she said she had a new med for MDD that she would give me samples of - Auvelity. I didn't hold out much hope, but on DAY ONE, I felt less anxious and steadier, mood-wise. I couldn't believe it. And I have done better ever since. My only problem was, I can't take two in a 24 hr. period - too much sleepiness. But I seem to be doing great on one! This is a miracle drug, but why it's so expensive is beyond me. Still, I'll take it!"

• fallout
• Taken for less than 1 month
• February 13, 2023

"This antidepressant has caused severe dizzy spells for hours on end, even after having taken it for a week. It also has increased my anxiety and seems to be making my tinnitus significantly louder. Not impressed."

• scott...
• Taken for 1 to 6 months
• January 2, 2024

"This stuff is amazing. I'm actually taking Wellbutrin 150 mg 2/day and 30 mg pure DXM tabs 2/day for a couple of months now. I'm 51. I've tried Zoloft, Paxil, was on Lexapro for many years, but nothing even comes close to this - cough medicine! I discovered this Wellbutrin/DMX combo by accident when I had a nasty cold and was taking DXM on top of the Wellbutrin. The negative self-talk, the depression, the suicidal ideation, all went away. I hope it continues!!"

• A Per...
• Taken for 1 to 6 months
• March 10, 2024

"I have severe, treatment-resistant depression. Been through four rounds of TMS and 22 medications. Auvelity has been unlike any mental health medication I've taken. The first few days, I felt outside myself, cloudy. When I went up to twice daily, it got to a point where I didn't feel safe driving. I stopped, restarted, went up to two slowly. I started with one dose late in the evening and gradually took it earlier. I then added the second dose before bed. I take it at 10 AM and 10 PM. I don't take it unless I've eaten something. Depression has improved a lot. So has my anxiety and paranoia. No more weird 'high' feelings, but it does make me drowsy. I'm one to struggle to sleep. Not anymore. I close my eyes and I'm out. Sometimes for 10 hours. After the first dose, sometimes I need an energy drink to stay awake. I can't brew the coffee strong enough. But I'm not suicidal. The oppressive, depressed 'doom' feeling is mostly gone. Not perfect, but the best so far."

• aek
• Taken for less than 1 month
• April 6, 2023

"Unfortunately, this medication made me really sick. The side effects described came on after 10-12 days on the full dose: severe anxiety, loss of appetite, headaches. All came together with severity, so be careful with this drug. I had never experienced this before, and it was awful."

• cyndee
• Taken for 1 to 6 months
• April 20, 2024

"I’ve suffered from MDD for over 5 years and have been on many different antidepressants and therapy during this time with no improvement. I had suicidal ideation and panic attacks so severe that I quit my job and spent most of the last year in bed. Within a few days of taking Auvelity, my symptoms decreased and within a couple of weeks, they were gone. My only side effect is that I get a little dizzy when I stand up, which is nothing compared to what I’ve been suffering with. I can’t say enough positive things about this medication, which in my case, has changed my life for the better."

• idbh
• Taken for less than 1 month
• April 7, 2024

"I met with a new psychiatrist last week and explained that in the past 24 years I've tried almost every antidepressant but the MAOIs. Nothing helped longer than a month. I stayed on Lexapro since it helped with the irritability, but that went away years ago. He told me about a new antidepressant that is unlike SSRIs in that it takes effect very quickly, rather than weeks or months. I had basically given up any hope, but still agreed to try it. I'm on day 6 and I can already feel it working in a positive way. I have more energy, doing basic tasks don't feel like a major chore, my hygiene has improved, and I started to laugh again. It has been so long since something struck me as funny I thought I would never feel it again. I've also stopped grinding my teeth. I know it has only been a week, and based on past experiences it possibly could fizzle. I am just praying that it doesn't, because I actually feel like a human again."

• LauraJM
• Taken for 1 to 6 months
• January 22, 2023

"I suffer from medicine-resistant depression and PTSD and have been taking Auvelity in addition to other antidepressants for about 3-4 months. I initially felt better for the first month, but then I regressed again. It was frustrating as I had just refilled Auvelity with a $100.00 copay. I believe that this medication could work for people without resistance, it just didn't work for me."

• CAL
• Taken for 1 to 6 months
• May 10, 2024

"I have suffered with MDD for years and have tried numerous medications without success. I was hesitant to take Auvelity because I didn't want to be let down by yet another medication that didn't help me. However, to my surprise, within a week I noticed an improvement in my MDD symptoms. I've been taking it for 3 months now and I cannot picture going back to a life without it. The only noticeable side effect is short bouts of mania, but they don't impair my ability to work and function in my day-to-day life."

• itsju...
• Taken for less than 1 month
• May 3, 2023

"I’ve recently added Auvelity to my repertoire of meds. Sertraline has been very affective for my anxiety but I’ve still been struggling with depression. I’m about three weeks in and I can definitely say I’ve noticed some improvements in my depression. I’d say it took close to three weeks before I noticed a response and not the one week it says. Side effects have been minimal and I don’t notice any currently. So far I’m happy and I feel my depression lifting. Hoping this continues to work. Was on Wellbutrin for over a year and had no results with that. And tried a series of antidepressants, mood stabilizers and antipsychotics."

• STL
• Taken for 1 to 6 months
• October 10, 2023

"This drug was a life saver, literally if you know what I mean. Six months on Prozac (20 mg) after depression sudden onset was a disaster with trembling, brain fog, chest pounding anxiety, an eye floater, and gastrointestinal issues. Auvelity started to improve my mood within three days and got better once Prozac was out of the system over about a month. The early side effects were some weird tired feeling in my legs that went away after a few weeks. There is some mild shakiness a few times a day. Today I tentatively feel like a normal person again and almost like who I was before the depression onset after about 10 weeks of 1 tablet per day. Going to 2 gave me some anxiety, it seems 1 tablet is good enough for me. There is some fatigue associated with the drug but it is mild and not everyday. I was lucky to get prescribed Auvelity."

• Janie
• Taken for 1 to 6 months
• September 6, 2023

"I've tried so many different antidepressants. This one has made my mood lighter. I feel not so sad. Less crying spells. More motivation to feel like going out and doing something. Not so much hopelessness. More humor. More feeling like being social. (Forgot to say I'm on my second month of this med.) The downside is minimal. When I do yard work or housework - I sweat way more than I used to. Sometimes a little clumsy. Slightly confused at times. A little more forgetful. A little more hungry, but no major weight gain. For me, this med has been a lifesaver. I have enjoyment where before I had very little. I've had some sexual side effects which I don't like. All in all - much improved. Much better. Hope this helps!"

• Kelly
• Taken for less than 1 month
• August 15, 2023

"I've been on Auvelity for 2 weeks now. I swear I felt a difference on day 1 but wanted to wait a while to see if it lasted or if I got any side effects. I can see the beauty in things again & catch myself smiling a lot. I've been majorly depressed since 2012!! This has been a life changer so far. I even have it in me to get up and take care of myself or complete a task that needs done. I'm almost back to who I was before the trauma and MDD. If you've tried a ton of other antidepressants that didn't work, ask your dr about Auvelity! Also, my anxiety has lessened greatly on this med. I don't take my Xanax as nearly as much as I used to before Auvelity. I also take Zoloft (200 mgs a day) still for depression."

• Lexi
• Taken for less than 1 month
• January 9, 2023

"I have had some success with Wellbutrin (Bupropion), but after a number of years, I seemed to have developed a tolerance. An increase in dosage caused me to have anxiety. I was hopeful Auvelity would help as it has similar properties. Sadly, the smallest dose created overwhelming anxiety that felt like I had taken a high dose of Wellbutrin. Although one should not expect half a sustained release, I was hoping it would reduce the anxiety. Auvelity, I felt, gave me more energy and even curbed hunger, which was a positive. Though, sadly, I still had severe anxiety, was jittery, and my heart was pounding. I couldn’t continue and went back to regular bupropion while searching for something else."