Skip to main content

Auvelity for Major Depressive Disorder User Reviews (Page 4)

Auvelity has an average rating of 8.4 out of 10 from a total of 103 reviews for the treatment of Major Depressive Disorder. 78% of reviewers reported a positive experience, while 8% reported a negative experience.

Reviews for Auvelity

  • SJM
  • Taken for less than 1 month
  • September 3, 2023

"After 6 days, I feel less depressed & have more energy. I hope I can stay on Auvelity because I do have side effects of diarrhea with abdominal pain & an increase in tinnitus. I am taking 1 tablet a day."

8 / 10
Was this helpful?YesNo
12 Report
  • litvos
  • Taken for 1 to 6 months
  • September 1, 2023

"I've been taking this medication for six weeks. It is a life changer. If you also take ketamine infusions, 100% will change your life. I started experiencing some side effects like sleepiness probably after 3-3.5 weeks from the start. I am okay with this side effect. I didn't feel that good since 2005. Unfortunately, my insurance doesn't want to cover it anymore. Not sure what I would do without it. Tried many different prescriptions. ketamine infusions help, but they're crazy pricey, and you need to do it every four weeks. This medication is a game changer."

10 / 10
Was this helpful?YesNo
12 Report
  • Chron...
  • Taken for less than 1 month
  • September 23, 2023

"I have been on a variety of antidepressants for the past 15 years. I started Effexor about 6 months ago, and it was life-changing, but I still had depression and my anxiety was paralyzing. My psychiatrist put me on Klonopin for anxiety and Auvelity for depression. I was very hopeful this would be the combination that would allow me to function. The first week, I felt amazing despite having intense nausea and generally feeling kinda loopy like being on a pain pill. By week 2, those side effects went away. Now, I can’t wake up and can’t stay awake during the day. At first, it was just general tiredness, but now I fall asleep throughout the day, including while driving, regardless of how much caffeine I have had to help me stay awake. Although my depression has decreased, I go through intense and unexpected mood swings. I can be extremely happy and excited about an upcoming event and then randomly fall into a deep depression while on the way there. After a bit, I’m fine again."

5 / 10
Was this helpful?YesNo
11 Report

Frequently asked questions

  • Bob
  • Taken for less than 1 month
  • February 10, 2023

"After the fourth day, I developed a violent cough. My doctor instructed me to stop taking the medication, but the frequent dry cough persisted for 2 months I was previously prescribed Wellbutrin 20 years ago, which at that time was the best drug for me and lasted for 13 years before it stopped working"

2 / 10
Was this helpful?YesNo
16 Report
  • CTCin
  • Taken for less than 1 month
  • April 24, 2023

"For reference, I’ve been on Wellbutrin and Effexor for several years. I stopped the Wellbutrin when starting Auvelity and I just started weaning off the Effexor this weekend, so it’s too early to tell. However, since I do feel “lighter” already I’m hopeful. The first couple of days at the full dose caused some dizziness and mania about two hours after taking but both have decreased. I took the second dose a little later last night and now I feel extreme fatigue so I’m going to be more diligent about taking it earlier. The doctor said the side effects should go away soon so I’ll update here. Again, I’m hopeful!"

8 / 10
Was this helpful?YesNo
14 Report

Are you taking this medicine?

  • momto...
  • Taken for less than 1 month
  • January 22, 2023

"I started Auvelity a few days ago. Some background information about me is that I’m on 450 mg of Wellbutrin and 40 mg of Lexapro. Unfortunately, the Wellbutrin or the Lexapro isn’t helping. I’ve been on Wellbutrin for 4 years and Lexapro for 3 years. My question is, have any of you been on Wellbutrin and switched to Auvelity? Doc switched me to one Wellbutrin per day, along with two Auvelity per day. If any of you have had the same experience with this same combination, I’d love to hear about it. I’m curious since Auvelity and Wellbutrin have bupropion in it. Thanks!"

Was this helpful?YesNo
15 Report
  • Marjo...
  • Taken for 1 to 6 months
  • August 8, 2024

"Improvement in that depression doesn't seem as deep or last as long. Only side effect that interferes with my day is sometimes I am very dizzy and definitely would not drive. I take the regular dose of 45/105 mg twice a day. I do take other meds that might increase the dizziness - my doctor knows all of my meds. I have been taking it for 4 weeks. Simple to take."

9 / 10
Was this helpful?YesNo
1 Report

More FAQ

  • Ricky
  • Taken for less than 1 month
  • January 8, 2024

"Started taking this medicine 6 days ago. It started making a difference today because I usually wake up around 3:30 ruminating and very depressed. This morning was much better. I didn't have the negative thoughts as bad and could let go of the rumination. However, after my second dose today, I'm super dizzy and irritable, so I'm hoping that goes away. I had a great day today, and I think it may be working, just not sure if the dizziness is from this medicine or the discontinuation of my Lexapro."

8 / 10
Was this helpful?YesNo
7 Report
  • hatem...
  • Taken for 6 months to 1 year
  • March 13, 2024

"I was on one Auvelity a day (45mg) even though the doctor had prescribed two a day for me. About 8 months after taking one a day, I felt my depression getting worse, so I told my doctor I would take two, his original prescription dosage. Two and a half to three weeks later, I have been experiencing much increased anxiety, feelings of discomfort and restlessness/nervousness, extreme agitation and fear. I did not know what was wrong with me until I decided to look up Auvelity side effects, which is why I will be going back to one tomorrow and calling my doctor. Another disappointment from the medical community that causes more problems."

6 / 10
Was this helpful?YesNo
5 Report
  • Kathy
  • Taken for less than 1 month
  • August 3, 2024

"It has really helped with my depression, and I have been taking it for almost a week, so it’s fast acting. However, the side effects are making me want to stop taking it. I have chest pain, jaw pain, dizziness, horrible headache, excess sweating, vision changes, shortness of breath, and I almost pass out every time I stand up. I’ve continued taking it, though, in hopes that the side effects will subside because it has drastically improved my mental health, and I no longer have suicidal ideation. I love everything about it aside from the side effects."

7 / 10
Was this helpful?YesNo
1 Report
  • Rob
  • Taken for 1 to 6 months
  • May 18, 2024

"My experience has been a positive one. I have been taking it for a few months now and after trying everything else, Auvelity plus Zoloft works. I'm just curious how everyone is paying for this expensive lifesaver."

9 / 10
Was this helpful?YesNo
3 Report
  • AnL
  • Taken for 1 to 6 months
  • May 23, 2024

"I started taking Auvelity as a supplement to my antidepressant as I became resistant to treatment. At first, I took one a day. I didn’t see much difference. So, my doc switched to 2 a day. I think it helped. But I started having a very dry mouth. It is affecting me, and I am not sure what to do about that."

8 / 10
Was this helpful?YesNo
2 Report
  • Anonymous
  • Taken for 1 to 6 months
  • August 1, 2024

"I took this medication for 2 months. It did seem to improve my depressive symptoms within the first 72 hours of starting! However, I noticed that my feet were swelling. It got to the point where my left foot and ankle were constantly swollen. I didn't think it had anything to do with this medication, so I continued to take this while I worked with my primary care to figure out what was causing the edema. There were no answers, so I decided to stop Auvelity, and within 48 hours the swelling was gone. I have since stopped taking this medication due to my personal reaction."

7 / 10
Was this helpful?YesNo
0 Report
  • Spkit...
  • Taken for 1 to 2 years
  • August 22, 2024

"It helped me feel immensely better from chronic, treatment-resistant major depressive disorder. It helped me feel more normal than anything else I had tried in the last 20 years. I could not take it twice a day, or I wouldn’t be able to sleep at night. So I only took it once in the morning, and it still seemed to make quite a difference. It causes mild diarrhea daily, but not enough that it’s terrible."

9 / 10
Was this helpful?YesNo
0 Report
  • behin...
  • December 5, 2022

"This drug is really helping me out and acted in less than 2 weeks."

10 / 10
Was this helpful?YesNo
45 Report
  • Depre...
  • Taken for less than 1 month
  • November 19, 2022

"Really great experience, feel a lot better. Have only been taking it for a few weeks though so we’ll see"

10 / 10
Was this helpful?YesNo
37 Report
  • Mary
  • Taken for less than 1 month
  • July 14, 2023

"I've been on this drug for 2 weeks and every day is better. I actually get out of bed. I've tried several other rx and over time they go flat. I look forward to my continued improvement."

10 / 10
Was this helpful?YesNo
26 Report
  • Chris
  • Taken for 1 to 2 years
  • July 17, 2024

"After 12 years of depression and trying everything else on the market, my doctor prescribed this, and it worked."

10 / 10
Was this helpful?YesNo
4 Report
  • jako
  • Taken for less than 1 month
  • May 24, 2023

"From the first day, it worked well. It raised my spirits a lot, and gave me energy, calmness, and the desire to do things."

10 / 10
Was this helpful?YesNo
24 Report
  • Sunny...
  • Taken for less than 1 month
  • December 24, 2022

"I haven't had any side effects. I'm on day 3 and taking it with Lexapro and Hydroxyzine. So far so good."

10 / 10
Was this helpful?YesNo
29 Report
  • garyh...
  • Taken for 1 to 6 months
  • August 29, 2023

"Never felt better, cannot afford. Cost first time $95.00, second $95, third $114, and then off the wall $270.00! I can't afford to take it but I can't do without. Fixed income, 77 years old."

10 / 10
Was this helpful?YesNo
18 Report
  • jane
  • Taken for 6 months to 1 year
  • June 4, 2023

"Helped with energy, anxiety, and having an interest in life again."

10 / 10
Was this helpful?YesNo
21 Report
  • kathun
  • Taken for 1 to 6 months
  • May 31, 2023

"I don't get it. I think it's very overrated but that's just my opinion. I am disappointed, too because I really wanted this to be it."

4 / 10
Was this helpful?YesNo
21 Report
  • Miguel
  • Taken for 1 to 6 months
  • April 21, 2023

"Worked very well on me and from the very first week. Works similarly to ketamine, without the hassle of taking a scheduled drug."

9 / 10
Was this helpful?YesNo
21 Report
  • Jpal
  • Taken for 1 to 6 months
  • March 18, 2023

"Took for 3 months . Started asking if there were people in the house . Stopped taking and feeling very lightheaded. Did not work for me ."

4 / 10
Was this helpful?YesNo
21 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

Learn more about Major Depressive Disorder

Care guides