Pylera and Headaches: What Users Say (Page 2)

• CeC...
• Taken for less than 1 month
• March 28, 2018

For Helicobacter Pylori Infection "Today is my last day taking 14 pills a day (WooHoo!!) and I wish I would have found this post sooner. It's calming to see I'm not alone in all of these side effects. End of Day 1-10: dark/brownish colored urine (really freaked me out!). Day 2-10: metallic taste. Day 3: slight headache. Day 4: slight headache, decreased appetite. Day 5: decreased appetite. Day 6: decreased appetite, dark stool. Day 7: fatigue, dark stool. Day 8: intense headache, fatigue, black stool. Day 9: peripheral neuropathy left leg and foot (again freaked out!), extreme fatigue, black stool. Day 10: numb toes left foot, EXTREME fatigue, black stool. Mucusy off and on throughout (running nose, phlegm, light vaginal discharge)."

• CeC...
• Taken for less than 1 month
• March 28, 2018

For Helicobacter Pylori Infection "Today is my last day taking 14 pills a day (WooHoo!!) and I wish I would have found this post sooner. It's calming to see I'm not alone in all of these side effects. End of Day 1-10: dark/brownish colored urine (really freaked me out!). Day 2-10: metallic taste. Day 3: slight headache. Day 4: slight headache, decreased appetite. Day 5: decreased appetite. Day 6: decreased appetite, dark stool. Day 7: fatigue, dark stool. Day 8: intense headache, fatigue, black stool. Day 9: peripheral neuropathy left leg and foot (again freaked out!), extreme fatigue, black stool. Day 10: numb toes left foot, EXTREME fatigue, black stool. Mucusy off and on throughout (running nose, phlegm, light vaginal discharge)."

• Kin...
• April 9, 2017

For Helicobacter Pylori Infection "I feel like I have been poisoned. Even though people react differently to every medication, I'm sure this one beats all bad side effects by a long way. After having H. pylori, I began with Pylera treatment for 10 days... couldn't get through it for more than 7 days as my health started taking a heavy toll. Headaches, mood swings, bloating, painful constipation, extreme fatigue, chills, and then I stopped when I had a hives allergic attack, which obliged me to stop working. I'm an otherwise healthy 32-year-old who has had her life turned upside down by Pylera. After stopping treatment, I noticed I had developed an oral thrush due to antibiotics killing my intestinal flora and was sick in bed. Be warned as to the bad side effects and look for natural remedies!"

• Ze ...
• April 4, 2017

For Helicobacter Pylori Infection "Finished my 10-day treatment a couple of days ago. Before starting with Pylera, I read all these reviews to know what to expect from side effects. Mine were dark stools, dark urine, upset stomach/intestine, bloated for 1-2 days, headache, dizziness, weakness. No diarrhea or vomiting. I always had full healthy meals and some snacks before bedtime, avoided milk and similar, as well as spicy food, juice, etc. I still feel somewhat weak, but nothing compared to during the treatment. Let's see what the outcome of the stool exam is. Good luck, all."

• Nad...
• September 24, 2019

For Helicobacter Pylori Infection "Don’t even dare to take it with dairy like milk or yogurt. It was one of my worst nightmares. I couldn’t even stand up to go to the bathroom. This medicine makes me feel I’m walking in empty space, no concentration and bad, very bad mood. Headache and my eyes are burning me. I’m on my fifth day, and I hope I will overcome these symptoms soon. My tongue turned black and my stool too."

• Nev...
• May 31, 2015

For Helicobacter Pylori Infection "Never take this drug. There are other alternatives. I am on my 6th day, and I have numbness in my hands, diarrhea, headaches, nausea, extreme fatigue, and now I am breaking out in acne all over my body. Talk to your Dr about other alternatives. This is horrible beyond explanation."

• don...
• April 28, 2017

For Helicobacter Pylori Infection "Let me start by saying everybody's experiences are different, but after reading all the reviews, I seriously expected the worst. I am now on day 7, the first day was okay, 2nd day slight headaches, 3rd day when I went to bed, I had a stomach spasm. Once I went to the bathroom, I was fine. Yes, you have headaches, but I take Advil for them. Slightly constipated, and the stool is dark, urine was dark, but the worst of it all for me was the nasty taste in my mouth. No vomiting, no diarrhea, just make sure you eat with your meals and take a probiotic. I take Accuflora. I read some people say don't eat yogurt, I did, and I was just fine. 3 more days to go, let's all pray this works. Oh, and I missed just one day of work."

• ENa...
• February 14, 2018

For Helicobacter Pylori Infection "Day 5. I am exhausted, lots of dark, loose stools, dark urine, dizziness, nausea, and headaches. Started getting the chills this morning. I'm contemplating whether to stop this medication altogether. This is my second treatment (different course of antibiotics). Omg.. Help..."

• Ska...
• July 13, 2016

For Helicobacter Pylori Infection "Day 1 - Started with first dose after breakfast. Full meal and 16-ounce glass of water to wash down medicine. Second dose taken six hours later with a full meal at lunch. Also drink 16 ounces of water with medicine. Around 2:30 in the afternoon, started to develop a headache. I drink more water to see if that would help. Around 3:30, my headache was much worse, and I started developing a stiff neck. Took my third dose at 6 PM with a full meal and 16 ounces of water. 30 minutes later, I got really nauseous and threw up four times. I have never thrown up this much in my life. I contacted the pharmacist, and she told me to stop the medication immediately. I also contacted my doctor, and she told me to stop, as well."

• Ste...
• Taken for less than 1 month
• February 16, 2018

For Helicobacter Pylori Infection "I was given Pylera after being diagnosed with H. Pylori. I am a very active and healthy 41-year-old male. I'm 5'7" and 150 lbs. I will tell everyone that this medicine is TOUGH! All the way around. I'm on Day 6 of a 14-day regimen. I constantly have a metallic taste in my mouth, a slight headache, and severe nausea. I started the Pylera Saturday and have thrown up most every day and sometimes multiple times a day. I tried working on the meds, but I find it VERY difficult. I've had to use vacation days while on this medicine. I just physically cannot do it with the extreme fatigue and nausea/vomiting that I'm experiencing. I also have dark stools and diarrhea at times. My urine is also dark. My doctor did call in Zofran 4 mg for nausea on Day 4. The Zofran has helped. But I will say that my girlfriend says that I'm acting more like myself despite the severe side effects. It's like I'm being poisoned, is the best way I personally can describe Pylera. Good luck to all."

• Anonymous
• Taken for less than 1 month
• August 23, 2017

For Helicobacter Pylori Infection "Day 1-2: sweet metallic taste in the mouth after taking the drug. Day 3: sweet metallic taste in the mouth, some extra production of saliva, feeling very tired and sleepy in the 2nd half of the day, reduced appetite. Day 4: feel great in the morning, sweet metallic taste, irritated tongue, excessive production of saliva, mild headache, weakness, black stools multiple times a day and at night, ringing in the ears, reduced appetite. Day 5: sweet metallic taste that doesn't go away, tongue hurts, mild headache, feeling weak and sleepy, black stools many times, ringing in the ears, no appetite, slight dizziness, blurred vision, excessive production of saliva, vomiting several times 15-30 minutes after the 3rd dose, chills, heart palpitations, cramp."

• Tuc...
• Taken for less than 1 month
• January 19, 2017

For Helicobacter Pylori Infection "This is my third time that I have had the H. pylori bacteria and my first time taking Pylera. Well, personally, it has not been a fun ride, and the side effects have not been positive for me. I've been having terrible headaches, dizziness, feeling like I'm going to vomit, and a horrible taste in my mouth even with water. The positive side is I'm not hungry like I used to, so I force myself to eat something in order to take this medication. I have already missed a day from work because I was not able to keep myself focused, and the headaches are killing me. Staying positive."

• Unk...
• July 9, 2017

For Helicobacter Pylori Infection "Took a 14-day course, changed my diet to only organic fruits and veggies, no sugar, no box or packaged products, took probiotics with every meal. Experience the following: Day 1 - mild headache for 2 min. Day 2 - dark urine in the morning and tingle in the foot. Day 3 - dark urine in the morning, dizziness in the evening. Day 4 - back pain, tingling scalp. Day 5 - sore right shoulder. Day 6 - bloat after eating. Day 7 - bloat. Day 8 - headache nonstop, slight chest pain, but lots of energy. Day 9 - slight chest pain, but lots of energy. It does get better after a few months. Now I have gotten rid of the bacteria. My only side effects are slight chest pain, possibly costochondritis from inflammation, some neck pain. Keep faith, I'm 80 percent healed."

• Anonymous
• Taken for less than 1 month
• April 25, 2015

For Helicobacter Pylori Infection "I am on day 8. Finally starting to feel somewhat normal again. This medicine has made me feel horrible. The first few days, I was extremely agitated with crying bouts that are completely abnormal for me. My doctor told me that it's a side effect, but I have seen several people mention the same issue. I still have a general feeling of being anxious and feeling ill. Nausea, vomiting, diarrhea, and headaches have all been frequent. Stool is very black. Metallic taste and dry mouth. I can say eating well before each dose and drinking water seems to have helped. I wish my doctor had given me more information, so I was at least prepared. I won't know until 3 months if it works - for my breath test. If it works, I suppose it is worth it."

• Jaz...
• Taken for less than 1 month
• April 10, 2018

For Helicobacter Pylori Infection "I just finished my 10-day treatment last Thursday, 4/12/18. I was very skeptical after reading all the bad reviews on this medication, but I do have to say that for me, the only side effect I had was a headache from the day I started until the day after I stopped, other than that, nothing. I have a high tolerance to meds, so I hope this works for me so I can go ahead with surgery. I go back the 3rd week of May for my breath test."

• Fai...
• Taken for less than 1 month
• June 3, 2022

For Helicobacter Pylori Infection "I tested positive for H. pylori on a blood test with results past the scale in 2013. I took the amoxicillin and clarithromycin with bismuth and Protonix for 14 days. I never had a test afterward due to no insurance, so I don't know if it was eradicated. Fast forward to May 2019, EDG showed negative for H. pylori, so they took my gallbladder out. I still had symptoms off and on since 2013. Fast forward to now, May 2022. I had another EDG due to recurring symptoms. EDG pathology showed negative, but the CLO test showed positive. I started the Pylera 5 days ago, and it has been nothing but a nightmare! Day 1, I immediately felt exhausted and nauseated. I wasn’t able to eat much prior due to extreme bloating and nausea. Each day since has just continuously gotten worse. Whole body aches, exhausted, brown urine, black poop (what little I am pooping due to not being able to eat), headaches, weak as if I have the flu. I’m taking the 3 capsules of Pylera every 4 hours with two 40 mg Protonix daily. I’d rather die than take this again."

• ADM...
• Taken for less than 1 month
• March 10, 2021

For Helicobacter Pylori Infection "I'm on day 3 of treatment, I get side effects of headaches, body aches. I get very tired and sleepy after taking this medicine. I also have a weird taste in my mouth, even water tastes weird to me. I feel heavier even though I have been eating less and healthier, and I feel general inflammation in my body, especially in my legs and feet. No nausea so far, thank goodness! I hope this treatment works."

• mam...
• March 25, 2015

For Helicobacter Pylori Infection "I am on my 7th day at Pylera, and so far, everything is good. Yes, I feel a little bit tired, had a few headaches, especially in the mid-frontal head, and I had a metallic taste every morning; however, I've been eating better. I had some diarrhea the first days, and now my stools are better. It is annoying to take 12 pills a day and be on top of schedules. I also take probiotic yogurt, even though my gastroenterologist did not tell me about it. I hope this works."

• gra...
• March 27, 2017

For Helicobacter Pylori Infection "It is a hard treatment to do. I don't know yet if it is effective or not. I'm on my 6th day taking this medicine. I'm not able to work. I have a lot of side effects: headaches, dizziness, vomiting, diarrhea, black stools, dark urine, etc. I already read the prescription again, and it says: 'Do not have milk or dairy products while you are taking this medicine.' I'll avoid these products, and I hope to feel better."

• Sam...
• Taken for less than 1 month
• January 22, 2019

For Helicobacter Pylori Infection "I am on day 6, and let me tell you, that med is so nasty that it is the most hated med in my life. At day 2, I started having nausea, dark stool, headache, and just sometimes an uncomfortable feeling, and dark urine started at day 4. I wish I never went to the doctor or got this med. I hope it works because I would be annoyed after all that suffering, it must give me relief. I avoided everything they said to avoid, and the side effects still didn't go away. Hope that is helpful."

• Anonymous
• Taken for less than 1 month
• May 19, 2017

For Helicobacter Pylori Infection "40 years young female. I consider myself an average, slightly overweight but generally healthy woman who exercises 3 days a week. Before starting with Pylera and Creon, I read all these reviews about H. pylori bacteria. On meds now, 8th day. Side effects terrible day 1-2, vomiting, uncomfortable, uneasy. Felt everything was dirty, cleaned entire house and laundry. Day 2-4: loss of appetite, extreme bloat, sleepless nights. Terribly tired, everything smells. Mood swings, heart palpitations, stools, dark urine, upset/pain stomach/intestine, bloated, headache, dizziness, weakness. I always had healthy meals: jello and yogurt. I still feel somehow weak, but nothing compared to 1-5. Still can't sleep, and the copper taste is worse, but I have intestinal pain."

• Efu...
• Taken for less than 1 month
• June 2, 2017

For Helicobacter Pylori Infection "This is Day 4 for me, and I feel like I'm pregnant, having morning sickness. Everything I eat, it comes right back out, slight headaches, very tired, and I smell everything, and it makes me nauseous! Please let these last six days come quick!"

• Bif...
• Taken for less than 1 month
• April 14, 2018

For Helicobacter Pylori Infection "I'm on day 5 of Pylera. I had dark, loose stools for the first 2 days and a nasty headache the 3rd. All that is gone now. I'm just extremely tired! Been napping 2 hours a day, and I couldn't stay awake to take my last dose, so I had to wake up and take it. I've been taking a strong probiotic with it and drinking 4-5 cups of tea a day (green, black, peppermint, ginger). Staying away from gluten too. Good luck, everyone! I've had this infection since 2008. Was on other meds then, but I guess I've had it and it never went away. I was deathly sick for a month, dropped under 100 lbs, and had 6 emergency visits all because of this nasty infection. Praying this finally makes it go away!"

• Rey...
• Taken for less than 1 month
• May 11, 2017

For Helicobacter Pylori Infection "It's only the end of day 2, and I am drained! During the day, I don't have any significant side effects except for being really tired and a minor headache. At night, I get a strong sense of nausea and loss of appetite. It's only day 2, good thing I have a doctor appointment in 2 days because an antiemetic is very much needed. Let's hope the next 8 days don't get any worse than what they are."

• koh...
• April 30, 2021

For Helicobacter Pylori Infection "What helped me was to be prepared for everything that could go wrong: - I talked to my doctor to prescribe me antifungal medication - I quit eating sugar (completely) - I took strong probiotics 2 times per day (about 15 billion live cultures), at least 2 hours distance from the antibiotics. - I made myself a plan with the hours when I have to eat/take probiotics/take medication. - I planned to start on a Wednesday, so that there is only one weekend in between. You can plan to have it over 2 weekends. Side effects: - The first night was bad, I shivered and had a terrible headache. The next day I got diarrhea and some fever. Took rehydration salts and a lot of mint tea. - Next days it got better, except for the metallic, bitter taste (chewing gum helped a lot), sometimes my tongue got darker and the stool was absolutely weird. For me, it was crucial to know why I need to go through this and to look at antibiotics as allies, not enemies. If you have concerns, talk to your doctor openly."