Imuran and Pain: What Users Say

• Anonymous
• January 28, 2011

For Ulcerative Colitis "Have been using for over two years after several episodes of prednisone. Have been almost completely free of symptoms and have no obvious side effects. I only use the bathroom once a day and stools are generally well-formed. No diarrhea at all. Can eat and drink normally (including roughage) but did have some pain after eating too much corn on the cob."

• chr...
• April 29, 2019

For Inflammatory Bowel Disease "Shortly after commencing Imuran at a low dose (50 mg/day), I developed a severe and persistent headache and also felt very tired and listless. One week later, everything got a lot worse: within 24 hours of commencing the higher dosage (100 mg/day), I began to feel extremely nauseous, and about an hour later, non-stop vomiting commenced. I couldn't even swallow a mouthful of water without bringing it up almost immediately. That night, all the joints in my body began to swell up and become very painful. By 3 a.m., I could barely walk, and by 7 a.m., my husband had to call in emergency services: my BP had dropped to 56/40, so I was immediately taken to the hospital, where I was treated with copious amounts of IV fluids, antiemetics, and high doses of corticosteroids. Over the next few days, I very gradually began to improve and was discharged from the hospital 6 days later, but it took many weeks before I was anywhere near back to normal."

• Sys...
• December 8, 2015

For Lupus "Have been on it for over a year, works okay at this point, still having some fatigue and still have pain and swelling in feet and hands. Also take Plaquenil, so this may be helping also. Would love to feel as good as the people on Benlysta :)"

• Imu...
• Taken for less than 1 month
• January 24, 2016

For Crohn's Disease "Imuran seemed fine for the first couple weeks, until I got a fever of 103 degrees. My doctor instructed me to stop taking the Imuran if my temperature reached 103 degrees, so I stopped for a week or so. My temperature returned to normal, so my doctor instructed me to start Imuran again. After one day's dosage, I experienced the worst imaginable pain in my whole torso. It turns out the Imuran gave me pancreatitis. I had to spend 3 days on an IV drip in the hospital and an all-liquid diet for a week after."