Alirocumab for High Cholesterol User Reviews (Page 3)

• Love
• Taken for less than 1 month
• March 24, 2018

Praluent (alirocumab) "I am a 64yr old female. I did my first shot yesterday. Had to go to ER with very high bp, rapid hear bears, swollen eye lids, jittery, head and neck pain, itching, red skin. It was a negative experience"

• JJ2905
• Taken for 1 to 6 months
• April 8, 2018

Praluent (alirocumab) "I have been on this drug for 3 mo. Everytime I inject---for 36 hours I get leg pain and hand cramps and feel very tired. I am unable to sleep due to the leg pain and both hands have severe spasms. Joints seem to be getting worse with movement in tennis and pickle ball . I am going to see my doctor and stop this medication. Will have to do diet alone because all statins cause body spasms and cramps"

• Nagi
• Taken for 6 months to 1 year
• October 16, 2016

Praluent (alirocumab) "Praluent was working great for the past 9 months without any side effects but during the last 3 weeks I started to have the symptoms of arthritis that is some pain in the joints. It improves some when I walk. I hope these symptoms will not further increase. Will update you in another 2-3 weeks."

• uniqu...
• Taken for less than 1 month
• April 29, 2020

Praluent (alirocumab) "Mine is the usual story. I got horrific muscle cramps, especially in my thighs, from taking even the smallest imaginable dose of a statin (5 mg per week). I just had to stop taking any statin. I tried diet alone to lower my numbers and that didn't work. I fought trying an injectable for my cholesterol/cardiovascular issues for several years until I didn't have any options left. Two weeks ago I gave myself my first Praluent injection. I'm needle phobic so imagine my surprise when I never even felt the tiny needle and had to check to make sure it was actually in my skin. Then yesterday I did my second of my two monthly injections and it was the same; over in about 5-10 seconds! This was the big hurdle for me, so if you think you can't do an injectable, try it. It's really no big deal. This drug costs me $250/month with my Blue Cross insurance. I am hoping as users go up, the price will go down. Time will tell if my cholesterol goes down."

• Syd
• Taken for 5 to 10 years
• April 29, 2024

Praluent (alirocumab) "I have been using Praluent consistently since 2018 (5 1/2 years) and have not experienced one side effect from this drug. My cholesterol count reduced substantially within two months and has been maintained well within acceptable levels, ongoing. I have had annual visits to the prescribing endocrinologist, complete with blood work analysis, and all measurements have been satisfactory. Prior to being prescribed Praluent, my cholesterol count was considered ultra-high, and I had to be taken off statins as they caused memory loss. Praluent has been far more effective in reducing cholesterol and has done so with no side effects."

• Doone
• Taken for less than 1 month
• August 4, 2019

Praluent (alirocumab) "I have only been taking this medication Praluent a short time so I can't say whether it has helped reduce my cholesterol. What I don't like about this drug is that it makes me feel nauseous and I sweat profusely which is upsetting and embarrassing as I work part time at a store as a dressing room attendant or a cashier."

• mick
• Taken for 2 to 5 years
• May 12, 2020

Praluent (alirocumab) "I started on praluent 3 years ago not long after it was first introduced in the uk , after over ten year of on off , mostly off statins , due to there almost crippling side affects this drug has been a god send my cholesterol is below recommended levels for the first time ever for two years in a row, after having stents and one heart attack i now feel for the first time in years I'm no longer waiting for another imminent episode!. side effects, a few muscle aches but nothing like the statins and only last a short while.easy to take once every two weeks"

• Bon
• Taken for 1 to 6 months
• March 25, 2023

Praluent (alirocumab) "Been taking 150mg of Praluent for 2 months now. The first month was perfectly fine, had no problems as I inject it in my thigh areas. However, I got a big welt and itching in that area from the third injection. I changed the injection site to my other thigh for the fourth injection and had the same side effect. Showed my cardiologist when I went in for a follow-up, but they did not seem concerned as levels were down. I’m allergic to all statins and had to try something, will continue if this is all that happens I can tolerate it with anti-itch cream. I will discontinue though if more side effects appear. Will see what happens in my third month. I’m 71 years old and have had 2 stents over 21 years. My high cholesterol numbers just jumped in the last year, possibly due to age as I’m a healthy eater, and I exercise three times a week. Will update again in 2-3 months."

• Anonymous
• Taken for less than 1 month
• June 8, 2023

Praluent (alirocumab) "I took the first Praluent 150 injection and on the 3rd day after I got a terrible UTI. On day 5, I got severe body aches and muscle spasms. I’m on my second antibiotic for the UTI. I went to the doctor once and 5 days later ended up at the ER. I’m supposed to take my 2nd injection on Saturday but that won’t be happening. I’m just hoping my body gets back to normal soon. The Praluent injection was worse than Crestor or Lipitor for me."

• biker
• Taken for 1 to 6 months
• December 23, 2022

Praluent (alirocumab) "I have been on this for a month. Two injections so far. I am 64 years old, I exercise frequently, and have a history of cholesterol - total number under 200 however. Since taking this drug, I have been sluggish and fatigued. The fatigue comes and goes. Prior to taking this, I rode my stationary bike about 8 to 10 miles every other day. It is difficult to do what I regularly did prior to initiating this drug. Now, my exercise routine is tougher to do and I am very fatigued after riding. PSk9 inhibitors appear to have an impact on my blood pressure response to exercise. Hypotension response appears amplified (I am going for a follow-up on this). Research I have read on the PSK9's like this says, however, that the impact is "inconclusive" with respect to BP. However, I am more fatigued being on this drug. The first few days my cognitive abilities were impaired but this did improve. I also had more frequent nighttime urination. I am not taking a third Praluent injection."

• Meano
• October 11, 2018

Praluent (alirocumab) "I have had two shots getting ready for my third not sure if I want to take it because I've had chills, headache nausea a lot also aching. I'm going to get my blood test tomorrow to see if it's lowered it enough for me to keep taking this cuz the side effects for me are horrible. Also my blood pressure goes from being high to drastically low."

• EdE
• Taken for 1 to 6 months
• June 6, 2018

Praluent (alirocumab) "My total cholesterol has dropped from 268 to 125! The “all important” LDL (bad cholesterol) has been reduced from 184 to 50! Dramatic reductions in just 6 weeks on 150mg every two weeks. My HbA1c is essentially the same at 6.6 (was 6.7)...not bad. Kidney, liver- all stable and ok. No side effects at all with Praluent. Statins are toxic to my system--not just side effects, but toxic."

• Crono
• Taken for less than 1 month
• December 23, 2020

Praluent (alirocumab) "Switched from repatha to praulent due to insurance. I injected first of the month. Now after 2 Er Visits and a bunch of prednisone, it's finally starting to leave my body. To recap. The next day I felt like I got hit with the flu and had no energy and felt like crap, shorty after my whole face, fingers and feet blew up and I has covered in hives, from head to toe. I'm a day done with my steroids and the hives are already coming back. Not as bad, but enough to be bothersome, especially during bed time. If you have any sensitivity to statins, I highly suggest you stay away."

• Lon
• Taken for 1 to 6 months
• July 20, 2018

Praluent (alirocumab) "After 15 years on statins I could not accept Iiving with the continuous aches and pains. After three months on Praluent I feel fine, no noticeable side affects, no problem with injections. Cholesterol numbers reduced dramatically."

• Diane
• Taken for 1 to 2 years
• April 11, 2024

Praluent (alirocumab) "I’ve been on Praluent for over 2 years and have not had any side effects. I take the injection every 2 weeks, and all cholesterol levels are very good. If I had read all of these negative comments before using this medicine, I would’ve been petrified to try it."

• Jrano
• Taken for 5 to 10 years
• January 24, 2019

Praluent (alirocumab) "Awesome stuff for me. No side effects. Cut the pravastatin in half 40mg pravastatin 1x daily plus 75mg alirocumab every other week HDL down from 399 to 85mg dl. Still taking the other stuff. Livolo works fairly well but not like this. Can't tolerate ACE inhibitors and some med put a bruise across my back within three days. instant kidney damage. Now blue cross wants to deny me the only med combo I could tolerate. Actually prime theraputics is doing that. Forwarding their denial to cardio and via my atty to oag and state insurance board. After one 4x cabg 3 stents 2 mi. Bilateral endarectomy and original LDL around 400. I think my widow will be a millionaire as for ME.. we can prove this is the best and most correct treatment plan and it did work for about 5 years until they decided they should play doctor..."

• Paul
• Taken for 5 to 10 years
• March 15, 2023

Praluent (alirocumab) "My family has a genetic history of high cholesterol. I've been using Praluent since it came out after the clinical trials. We arranged a cath lab examination two years after I started taking the Praluent, and everything looked normal around the heart, with no calcium buildup other than one little speck. I've never had a stroke or heart attack. My cholesterol levels are in the normal range but were high when I was younger. Statins had too many side effects, and I stopped using them. The side effects are minimal to date. I take two injections twice a month, 150 mg. each."

• Anonymous
• Taken for 5 to 10 years
• January 31, 2024

Praluent (alirocumab) "Fifteen years ago I had two stents as I was suffering from blocked arteries and terrible angina. I was only 43 years old. I took statins for years, as much as my body could stand, as I suffered from insane muscle pain to the point where I could hardly walk. Because of this, my statin use dwindled to once or twice a week. Five years ago, with my cholesterol high again, I had a minor heart attack. I was then given Praluent, and my gosh, what a savior! Cholesterol levels down to recommended levels and no side effects. I would probably say, without exaggeration, that this drug saved me!"

• Mike...
• July 14, 2016

Praluent (alirocumab) "I couldn't tolerate statins. Tried 3. Each one gave a lot of pain....liver and angina. I had to stop them. While off them for a month my Total Cholesterol went from 165 to 213, LDL's went from 65 to 110. Now my Total is 97 and LDL's are 24. I take Lovaza to keep my HDL's up at 45-49; they never were above 34 my whole life no matter what I tried. I have no side effects and I feel the best in 5 years."

• Ssbelts
• Taken for less than 1 month
• June 8, 2023

Praluent (alirocumab) "I have had a CV event and have very high LDL and high LPa and cannot tolerate statins. I started on Praluent and was fine right after the injection. But the first night I woke up with a very swollen tongue and lips and an extremely dry mouth and throat. Took 1/2 Benadryl which seemed to resolve. But over the next few days, I would experience bouts of extremely high BP and flushing of my face and chest (I tend to have low BP so this was very odd). High BP and flushing seemed to occur after any exertion and followed by extreme tiredness for a few weeks and my doctor told me not to take the next dose. Additionally, I have had very unusual headaches, and odd bruising, as well as pinpoint bleeding under my skin and bleeding (large thick clots of blood) from my nose. If I got bit by an insect I would have rubbery clots of blood on my skin. All very strange, and I will be glad when this med has worked its way out of my system (about 40 days). FYI I do have a lot of sensitivity to many meds so I am not surprised."

• Macem...
• November 19, 2016

Praluent (alirocumab) "After having a myocardial infarction on December 22, 2015 , I was still struggling to get my numbers down, after trying just about every statin on the market, they all made my body ache and my joints so stiff I had to have help getting out of bed. I changed physicians she tried another statin with no luck. She asked if I would be willing to try praluent injections. LONG STORY SHORT NOTICE SIDE EFFECTS NUMBERS HAVE DROPPED DRAMATICALLY AND I FEEL GREAT,only benefit on injections 3 months!!!!!! Thank God for this medication!!!!!!! Got help paying for this from the manufacturer!!!"

• CLano
• Taken for 1 to 2 years
• February 8, 2020

Praluent (alirocumab) "I have been on Praluent for about 2 years. My lab numbers are awesome. However, 2 weeks ago after my bimonthly injection I developed a terrible itchy scaly rash at the injection site. No problems with the next 2, but then same thing again (different site). Not sure what's changed."

• Ellie
• Taken for 1 to 6 months
• May 13, 2023

Praluent (alirocumab) "I found Praluent fairly easy to use however I experienced very little reduction in my levels. What I did experience was inflammation of two pre-existing weaknesses in my body - both my feet, and my right elbow. Neither of these things caused me great discomfort prior to Praluent but left me almost unable to walk and performing normal activities with my right arm was excruciatingly painful. I could no longer safely lift things like a kettle, or whipper snip, trim hedges, etc. - things I’d always easily managed. It took me a few weeks to connect the onset of this pain with Praluent but it reduced considerably after I stopped using the product. I will always have these weaknesses in my body but the inflammation caused by this medication is not something I am prepared to put up with for the rest of my life."

• GEB
• Taken for 6 months to 1 year
• August 3, 2023

Praluent (alirocumab) "Fatigue, lethargy, developed varicose veins in both inner thighs best described as parallel mirror twins. The breaks were discovered during a routine annual screening by my surgeon. The tears were serious. My doctor was concerned because previous procedures on legs were minor. My cholesterol was reduced by one hundred points. My memory improved... recall... somewhat. The medicine is brutal and fatiguing. Didn't realize how draining it was until it was interrupted. My energy returned. My dosage was 150 ml injection twice monthly."

• Chris...
• Taken for 2 to 5 years
• May 24, 2024

Praluent (alirocumab) "It has adjusted all my cholesterol levels into normal ranges when they used to all be outside of those ranges. Even when I was 25 years old and playing soccer, I had high cholesterol. I did not tolerate statins, as indicated by a *very* high 'Creatine Kinase, Total, Serum' blood test. Then, I had a heart attack and started taking Praluent. Now I am doing fine and all my cholesterol values are in normal ranges, plus, my cardiologist's stress tests are all normal. Obviously, it's working great for me. I only have minor side effects such as shivering for 1 to 2 minutes about once a month or so when sleeping."