Alirocumab for High Cholesterol User Reviews (Page 2)

• Frmr...
• Taken for less than 1 month
• April 30, 2016

Praluent (alirocumab) "My Cardiologist prescribed Praluent to control cholestoral. I had one injection in October of 2015. within 24 hours my joints swelled to the point where for example I could not safely grasp my steering wheel. My B/P rose by 52 points to 191/ 106. My Cardiologist made no diagnosis outside of it might not be the Praulent, but began to try every drug that was available. My new normal B/P is 161/98. I have contacted the manufacturer talked generlities for an hour,who cordially let me speak with their research person and we but was unable to get any list of could be's or look for's. After perusing the Internet today, I find that the injection could have caused Vasculitis or Immunogenicity."

• FtMye...
• Taken for 1 to 6 months
• March 4, 2016

Praluent (alirocumab) "I have experienced debilitating leg pain, brought on by simple walking, and not sure if related to Praulent. Began shortly after first injection and had increased in severity. Have seen many doctors without success. Any advice to Mike.schrider@jlodge.com. Thanks"

• CMano
• February 18, 2020

Praluent (alirocumab) "I was on a statin for several years, but in 2015 I had to have 2 stents put in. When cardiologist increased the statin I had side effects so had to stop it. She urged me to try Praluent saying it had little to no side effects. After 4 doses I got a UTI that didn't respond to the usual antibiotics and I ended up in hospitals for stronger antibiotics. Then a few weeks later I developed pain in my neck muscles that got so bad it woke me up, also had pain in hips and legs. Been off the medication for 3 weeks and symptoms have all but disappeared. Only good thing was my collateral went down almost 100 points."

• Krisvb
• Taken for 1 to 6 months
• September 24, 2016

Praluent (alirocumab) "Praulent dropped my cholesterol quickly and significantly. Unfortunately, the last 3 injections have been followed within a couple of hours by a rapid, irregular heart rate. Has anyone else experienced this "side effect"?"

• Anonymous
• Taken for 1 to 6 months
• October 14, 2021

Praluent (alirocumab) "Horrendous. I called the FDA. I had side effects of horrendous fatigue, flu like symptoms, muscles hurt feel very weak, muscle skeletal issues, burning, bad sinuses, tired, tired ,diarrhea after 4th bi weekly injection and insomnia. I was on a great path before this, my diet is good, I was active, now I can’t do walking and treadmill because I just feel horrible. To walk up stairs my legs feel so heavy. Would not recommend this to anyone. What’s the be point in having great cholesterol numbers if your quality of life is horrible. I’m just waiting for this stuff to leave my system. And praying it does no long term damage."

• Unhappy...
• Taken for 1 to 6 months
• August 17, 2020

Praluent (alirocumab) "So I have been on Praluent for a month. I was previously on Repatha doing great, however my insurance doesn't want to pay for that and made me switch. 2nd dose now have UTI, muscle pain and daily headaches. I go to my doctor in 2 weeks and see if I can go back to Repatha. I thought from the reviews they are the same however theses side effects are telling otherwise. Btw both give me stuffy nose but I can live with that one. The other side effects were what I had being on statins and this is the low dose of Praluent."

• Frida
• Taken for 1 to 2 years
• December 24, 2018

Praluent (alirocumab) "Dramatic reduction in total cholesterol after about 1.5 years. 62 year old female. Went from 250 down to now 107. Have gradually been getting more and more fatigued, weaker and now to the point I can't do my walks. Going to call cardiologist after the holidays. This is how I felt on statins after just a few days. I'm disappointed. Very easy to use med."

• Badge
• Taken for 1 to 6 months
• February 20, 2016

Praluent (alirocumab) "So far this drug is amazing! I did my first injection of 75 mg on 1-6-2016. I had a lipid panel drawn on 1-8-2106 to see what my starting base line will be. In the 48 hours between the injection and the lipid panel, the results were nothing less than miraculous. My total cholesterol went from 222 to 170, LDL from 152 to 96! I can't wait to see the results at 30 days and on. The self injection was virtually painless and quick. I didn't even have any injection site reactions like swelling or redness and I always have those side effects from almost all shots. I'm not on the Pralulent payroll, just a 68 year old man who couldn't take statin's and now have a great alternative drug. I hope you have the same results as I have.."

• RSU
• Taken for 1 to 2 years
• January 6, 2018

Praluent (alirocumab) "started Praluent 9/2015. Began cough/cold symptoms 1/2016. Injection every 2 wks. Symptoms got worse each time med was injected. 7/2016 Informed my Dr who said symptoms were unrelated. Between 8/2016 and 1/2017 went to the ER 5 times and spent 20 days in hospital. Bronchitis and autoimmune reaction. The med reduced LDL and destroyed my immune system. Had to receive infusion and still have very low IGG. Once I stopped it Took all of 2017 to start feeling a little better. Reported reaction to mfg and FDA. Thinking about seeking litigation advice."

• elena
• Taken for 1 to 6 months
• October 21, 2021

Praluent (alirocumab) "My mum (76) took Praluent 75 for some months and in a short time started complaining of elevated BP and feeling of ear pressure, something she never suffered before. After some months her total cholesterol showed a marginal reduction (200) but also a CPK elevation (245). Be aware of with this drug, it is still quite experimental, doctors will mostly deny its side effects as do the leaflets but they are all there ! Doctors only care of studies with a control group, but please also listen to the actual experiences from patients !!"

• a woman
• January 18, 2016

Praluent (alirocumab) "After three shots, my cholesterol came down over 100 points to 152 as did my LDL, down over 100 points. But am not happy with side effects of sinusitis and now earache. Whole face is throbbing from neck to face. Not sure if pain in arm is part of side effects. Am fearing other side effects noted on bladder infection. First three shots were samples, next will cost me about $50 a shot; having problems with prescription...pharmacy still working with Pharmaceutical Co. Will ask to discontinue even if all other statins have not helped.I am a 79 year old female."

• Michael...
• Taken for 2 to 5 years
• June 17, 2024

Praluent (alirocumab) "My Cholesterol was so high, I was destined to have a stroke. I am highly allergic to any Statin drugs, and had given up hope. Praluent has helped me to regain good health! My numbers are consistently in the 'good' range, and my family & I are relieved that I have a better chance of a long life!"

• Anonymous
• Taken for 1 to 6 months
• November 30, 2022

Praluent (alirocumab) "Like so many other patients I had unfortunately side effects too. Muscle pain, leg, arms, even feet and neck pain. Worst, my hands are really hurting me, getting cramps, special at nights, now way to sleep properly. I just took medication for only 3 month..... Right now I am taking nothing to get rid of all these side effects. I hope it will be better, I don't know what will come next. After all these readings I get the idea that all the patients using these drugs are "guinea pigs" to try out this medication. It is very expensive and costs the health system a lot of money. Why is this drug still on the market....? I feel with anyone of you out there and hope one day you will be pain free again."

• Big...
• Taken for 1 to 6 months
• March 28, 2021

Praluent (alirocumab) "Had my first heart attack at 41yrs old had 4 more ended up with 2 open heart bypass surgery’s my cholesterol was off the chart 80 mg of statins did little to nothing. Repatha was prescribed 4 days after the first injection I was bed ridden for 5 days, hands, hips, neck, shoulder, lower back and knees all frozen, I couldn’t move without pain. Was switched to Praluent and worse effects. I’ve been in construction for 40 years and now I can’t provide for my family But my numbers have never been better but I will never inject again"

• EDB
• Taken for 1 to 6 months
• November 23, 2017

Praluent (alirocumab) "I posted here in Aug stating that due to pain in my legs, fatigue, backache etc I had stopped this med. On a recheck w/doc in Sept I found that my chol had risen to 410! So rebound was terrible; double what it was pre-praluent! I am now back on 75 mg and will be rechecked in Dec. I am already experiencing nasal/mucous issues and some back pain and fatigue altho not as bad as when on 150 mg. What I'm wondering is if anyone out there knows if this can cause long term severe problems and has anyone talked to their doc about these side effects and if so what were their comments please."

• Mary
• June 10, 2023

Praluent (alirocumab) "This medication (Praluent) sent me to the hospital for three and a half days with pneumonia and UTI, after injecting the second dose I felt like I have injected poison into my body, the body pain and cramping were horrible, and there will be no third injection EVER."

• HAPPY...
• Taken for 5 to 10 years
• December 14, 2023

Praluent (alirocumab) "Been taking since it was experimental, over 5 years now with NO side effects before taking bad cholesterol was near 300 after the test it was around 50. I do and have recommended this medicine, it is a very GREAT med!"

• Neutr...
• Taken for 1 to 6 months
• October 9, 2019

Praluent (alirocumab) "3rd month at 150mg/month to 300mg/month. Some side effects sore muscles joints for a day or two. Nothing too bad see what happens after increase. When on Statins there is no sore muscles joints for a day or two it's all the time. This drug is much better. Going to once a month dosing so am only sore or sick 2 or 3 days out of the month. Not a bad trade off if you ask me."

• Beav
• Taken for 1 to 6 months
• November 17, 2019

Praluent (alirocumab) "66 yrs old, female, active tennis and daily walking; diagnosed heart disease but no symptoms. Can’t tolerate statins due to fatigue , memory, muscle issues. I’m on the bimonthly 75 mg Praluent for last three months. The shot is a sharp sting. The first week my legs ached really badly for 3 nites, couldn’t sleep , but that has diminished. Now after the shot , by the 3 day my legs are tired at nite, but It’s liveable. My chol numbers dropped dramatically from 350 (With HDL at only 50 a year ago). Now HDL is 127 and LDL is 60! Got much lowers and It Reversed. Great ratio. BUT liver enzymes are way up AST (was 26 to 130 now) and ASL up! But I had just returned from a cruise of heavy eating and drinking. So, now I cut out my nightly glass of wine completely, and will get a new blood test in a month."

• larry...
• Taken for 1 to 6 months
• July 17, 2017

Praluent (alirocumab) "I no luck with statins, Dr. put me on praluent (3.5 mo.) I have had 1 heart attack resulting with 1 stent before I started Praluent. I also have torticollis in my neck and buldge discs in back which I am treated for, but since I started Praluent seems like my symptoms are worse. My neck , back, and legs hurt. 2 weeks ago I thought I was having another heart attack, went to hospital ER pain eased and EKG came back normal, possible side effect? I am thinking about taking myself off Praluent, I am tired of feeling like garbage . I'm a 67 year old male ,"

• Allan
• Taken for 1 to 6 months
• October 7, 2021

Praluent (alirocumab) "Hi Just discovered this site, and reading through some of the reviews I now realise that I am not alone with all my negative thoughts with taking Praluent. I had heart bypass 2nd April 2020, and have been injecting Praluent last 4-5 months I have just had bloods taken by doctors to find out what is wrong with me I get results next week, and it is my intention to stop taking it immediately I do not recommend Praluent to anyone. Best to overhaul diet if needed, but do not take this drug. I have multiple issues with it. Everyone, please stop taking this drug, it is not safe. It might reduce your cholesterol, but at what cost to your general health. Stop eating red meat, fats, sugars, carbs, cakes etc etc, instead Take care Allan Scotland (54 yrs)"

• chevy...
• October 26, 2015

Praluent (alirocumab) "I have more frequent bowel movements but not diarrhea. My total cholesterol fell from 365 to 174. My HDL only decreased minimally from 42 to 37. My most interesting side effect is that I have had a tremendous increase in libido. I'm on testosterone replacement and about 8 meds for my heart disease and had minimal to moderate sex drive for about 5 years. There have been no changes in my meds or anything else except for the addition of Praluent. I am a 65 year old male."

• Gaige
• January 25, 2020

Praluent (alirocumab) "Hello I just got approved to use Praluent . I've had it for 4 days now. I'm too nervous to do the injection. So I've been reading all the comments that are helpful. The question I'm looking for does anyone know the size of the needle pls as I'm horrified of all needles pls???"

• Mike...
• Taken for 1 to 2 years
• February 28, 2020

Praluent (alirocumab) "I'm a 73 year old man. I had a heart attack 3 years ago at which time my LDL was 250mg. My cardio doctor put me on 40 milligrams of Atorvastatin (Lipitor) daily which lowered my LDL down to 125mg which was not low enough. He started me on Praluent 75mg painless injections in my upper legs once every two weeks that lowered my LDL to a very low 25 mg. after taking it for only two months with no side effects. I hope the price doesn't skyrocket so I can continue taking it til I die someday. I never thought I would get my LDL down to 25. It's unbeleivable. I hope it keeps me from having another painful heart attack. I'm told that Repatha and Praluent are about the same medicine."

• PEano
• Taken for 1 to 6 months
• May 1, 2020

Praluent (alirocumab) "I started taking Praluent in January 2020. A few weeks in I had an awful UTI. Never ever had one before. It was miserable. Then six weeks later had another UTI. Only thing new was the Praluent. I started looking into the side effects and see that was a highlighted side effect. As I read more on this drug I see it may be causing the fatigue and pain in my lower back and pelvic area. I told my doctor I wasn’t going to continue. This was a last option as I have severe side effects from everything else we have tried. I did have blood work the other day and my numbers were lower but triglycerides were still high."