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Differin User Reviews & Ratings (Page 3)

Differin has an average rating of 6.0 out of 10 from a total of 338 reviews on Drugs.com. 52% of reviewers reported a positive experience, while 37% reported a negative experience.

Reviews for Differin

  • Thyro...
  • Taken for less than 1 month
  • March 7, 2017

For Acne "I've always suffered with acne throughout my teenage years & adult life. I have PCOS & I had a full thyroidectomy due to thyroid cancer last year. I'm now 38. My hormones went crazy after surgery. I was breaking out terribly. I've tried every over the counter & natural treatment you could imagine. Nothing worked. I saw the commercial & was of course skeptical. I picked it up at target & started using it during my usual breakout time (week before my period) within a week it was cleared up! My acne scars are lighter as well. People at work are actually saying how good my skin looks! I wish I would've tried sooner. I use a very thin layer in common breakout areas. I also moisturize with coconut oil. Fantastic product!"

10 / 10
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32 Report
  • Sad
  • Taken for 1 to 6 months
  • January 27, 2020

For Acne "I had like a few breakout so went to dermatologist for medicine and they told me to use differin gel. I guess it works for some and not for all. Because I started with 2-4 pimples and then used the differin and now I have full blown acne. Like all over my face I used it consistently for 6 months. Never stopped until I realize it wasn’t working all it did was give me more acne and I hate my face and regret using this product. It said I would see difference In 12 weeks and no more acne but I saw a difference alright...... made my face horrible. So.. happy it works for some people I guess."

1 / 10
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22 Report
  • Tiina
  • April 3, 2017

For Acne "I have been using this gel for about 2 weeks now and have had nothing but positive results. I'm not exaggerating when I say this starting working on my skin immediately. I have been going through bad cystic acne breakouts and hormonal acne for the past two years now. Since I started using the differin, my breakouts are minimal with only one or two pimples but nothing like before. I was breaking out with 3-5 new pimples daily and the differin stopped that from happening immediately. I have extremely oily skin so the differin did not dry out my skin. I have also changed my face cleansing products and also changed my foundation at the same time. I would highly recommend this product for anyone who is at their wits end with adult acne."

10 / 10
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31 Report

Frequently asked questions

  • Anonymous
  • October 17, 2015

For Acne "I've used this product for 12 weeks now my comedone acne completely cleared after 8 weeks of use. Broke out a lot in the first 8 weeks but once I reached 8 weeks and onwards my skin has drastically changed. Would definitely recommend this for comedone acne and do try and persevere as it take at least 8 weeks to work."

10 / 10
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35 Report
  • steph
  • Taken for 1 to 6 months
  • July 15, 2021

For Acne "I've just passed the 2 month mark after having my doctor prescribe it to me. I've always used benzoyl peroxide, which has always worked for me, but I told my doc I didn't want to put something on my face every single night for the rest of my life. She prescribed Differin. She said I had to wait at least a month to see improvements, as purging is normal. 2 months later and I'm still purging. I've gotten painful acne in places I didn't have it before, and I'm overall very unhappy with the results. The prescription says it may take 1-3 months to see results, so I will continue for another month, but I don't think it'll make a difference. Would not recommend."

1 / 10
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15 Report

Are you taking this medicine?

  • nik
  • Taken for 1 to 6 months
  • December 30, 2020

For Acne "Hello I was excited to start this product. I knew I was going to have face purge. However it has been over 2 months and my face is really red and has so much acne. My face is worse than when I started. I don't want to give up but it is making it so much worse and I feel so ugly - disappointed."

2 / 10
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17 Report
  • Anonymous
  • July 25, 2017

For Acne "Well I've only been using this face med for a few days and my skin burns and is super dry!!! I put it on at night go to bed and wash my face in the am and apply makeup but I can't wear makeup because as soon as I apply it my face burns very bad. What do I do? Had Anyone experienced this"

1 / 10
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28 Report
  • Lila
  • Taken for 1 to 6 months
  • December 13, 2020

For Acne "Was on DIfferin for 3 months and it never gets better. I started with 2 acnes on my chin and now I had it on my forehead, cheeks & chin. Everyday felt like nightmare & I had major breakdowns here and there. I had high hopes for this product, but I guess it failed me."

1 / 10
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17 Report
  • megsie
  • June 24, 2016

For Acne "I've always had acne, ever since puberty started!! I broke out really badly at the start of this year probably because I went on a "TRY EVERYTHING" rampage and destroyed my own skin:( but yea it was one of the lowest points for me in terms of my self-esteem and confidence. I really hated looking at myself and I was so depressed. Anyway I was prescribed Differin by my dermatologist. Alas, after many painful months of breaking out, my skin slowly but surely cleared up. I would say, the initial months were VERY TOUGH but don't give up! BE PATIENT and you will see your skin transform! Give if at least 3 months"

10 / 10
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31 Report
  • Anonymous
  • Taken for less than 1 month
  • August 19, 2020

For Acne "I’m too old for this. I had some hormonal acne which didn’t surprise me since my skin is sensitive and acne prone. My dermatologist friend suggested Differin. What an awful experience. My skin looked worse even after 3 weeks that I had to stop using it. I had a lot of large cystic acne like a teenager, horribly embarrassing. Stopped it cold turkey and went back to 2% benzoyl peroxide and they went away in a week. Never again."

1 / 10
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18 Report
  • mary
  • September 25, 2016

For Acne "Struggled with acne for years, and this has honestly been a miracle worker. I've tried many different treatments (different strengths of benzoyl peroxide, oxytetracycline and limecycline) and I decided to use Differin before trying BC or accutane, and I'm so glad I did! The first week was tough, because my skin peeled rather a lot and felt extremely dry. However, I didn't experience any "purging", and the dryness was easily solved with a light moisturiser. After about 2 weeks, my skin was significantly clearer, and was no where near as dry as before. The gel has been the best treatment I've used by far, and I strongly encourage you to persevere with it as it's a game changer! My skin is now really clear and I have so much more confidence!"

10 / 10
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30 Report
  • Whitls
  • April 5, 2017

For Acne "I will be 30 in 3 months and my skin is worse then it was when I was 16! What the hell! I find it interesting that everyone who really enjoyed this product, properly used this product. I was prescribed Differin when I was in my teens and it worked wonders! Now thats its OTC, I recently started using it again. I am at the 4 week point, so yes my face is breaking out. I remember when I first used it years ago the same thing happened and with patience my skin cleared up. I have already noticed a difference in my cheeks which seem to not be breaking out as bad. I am patiently waiting for this period of breakouts to come and go, so I can see those great results once more. I used Differin as a teen and loved it."

10 / 10
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28 Report
  • Loopy...
  • October 16, 2016

For Acne "This cream has been amazing for me. At first I wasn't seeing anything good except more spots, and sore skin. My boyfriend said why am I using cream to make me look worse. But I knew you had to stick at it. I got frustrated so I applied peroxide as well which was great to rid the spots fast but meant my skin all flaked off. That was horible at the time but got rid of every scar and blemish. Like a chemical peel I guess. Then 2 months in I really noticed the difference. Now about 4 months in and for about 2 months now I have had skin I had wished for for years. Clear, and no marks and can leave without make up. I honestly wish this was over the counter and don't get why it isn't because it would help so many more people who dont go to the gp"

10 / 10
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29 Report
  • Anonymous
  • January 14, 2016

For Acne "Absolutely amazing! Since I have used this medicine my face has cleared up in less than a month! I had a lot of bumps on my forehead and pimples and my face including cheeks. I also feel that it is helping with my acne scars. I really hoped this helped and that more people can live with clear skin:)"

10 / 10
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31 Report
  • Mikei...
  • August 30, 2013

For Acne "I had clear skin all the way up to junior year. I became stressed out due to the work load and decided to buy products that contained chemicals such as benzoyl peroxide and salicylic acid. I even purchased a system, but I believe that it dried out my skin and produced an oil flare up. My acne was considerably worse after 30 days. I got cystic pimples. I finally convinced my parents to seek me a dermatologist. I was prescribed Differin lotion (0.3% adapalene) along with minocycline 100mg, twice a day. I wash my face now with Purpose gentle cleansing car. The first week I only used Differin because my insurance had not cleared Minocycline yet. I saw significant improvement. Almost my 3rd month and breakouts have ceased."

9 / 10
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37 Report
  • Grisa...
  • Taken for 2 to 5 years
  • February 28, 2017

For Acne "I've had acne when I was a teenager, it cleared up during my 20s then came back - with a vengeance - when I was 33. Differin gel and cream has been the BEST stuff I've used and I have used A LOT of different lotions and potions which have cost me a fortune over the years. I'm now 39 and still suffer breakouts but u keep a tube handy for them and it clears them up in a couple of days. I would say to ONLY put it on the papule or pustule and not on any clear skin around them. That's when it will make your skin flake and peel off! If you use on the spots ONLY it will work just fine. I'm also a beauty therapist and I recommend that some of my clients see their GP for it."

10 / 10
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27 Report
  • Jennyv
  • December 19, 2008

For Acne "My acne became worst within the first 2 weeks of using Differin, then all of a sudden it began to get better. The improvements must have happened at night because I would get excited in the mornings when I washed my face. I have to strongly agree with the person who posted before me. DO NOT GET YOUR EYEBROWS WAXED while using this product. My skin was ripped off and immediately turned red. A day or so later it left this large UGLY scar under my eyebrows. About a week later it peeled and was fine, but who wants to go through that."

9 / 10
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47 Report
  • Aryan...
  • Taken for 1 to 6 months
  • February 3, 2021

For Acne "So I had high hopes for this product. Not only because I had exhausted most topical solutions for my acne but because I had seen some great reviews online. My acne was mainly on my cheeks and some spots here and there on my forehead and chin. I never really experienced cystic acne until I started using this product, 3 months in and the purging hadn't stopped. I thought I'd give it more time, 4 months in the acne is cystic and has shifted to my forehead. My right cheek is mostly clear but I have acne on my left cheek. I'm 1 week away from 5 months and my skin feels greasy, I'm getting blackheads on my forehead not to mention I now have pitted scars and hyper pigmentation from the on going purge. I'm contemplating whether I should continue with this product till month 6 or pack it in and start on trying to clear my HPI and scarring. Right now I'm in the process of making my own coconut kefir so I can heal my gut using probiotic rich foods. I honestly feel like I'm at my wit's end."

1 / 10
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15 Report
  • Ashle...
  • April 17, 2017

For Acne "I used Differin gel for almost 2 years on my face. I had moderate acne that no OTC medication helped and some prescription medications didn't help much either. Differin took about 2-3 weeks of daily use before I saw any change but about 2 months into the treatment my face was pretty much all clear with no pimples. It was amazing. My skin did get red and itchy during those first few weeks but my doctor said it was common and to keep using because my skin would get used to it. It did and it still keeps my skin the best it's ever looked. Also, it's now available over the counter at drug stores."

10 / 10
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26 Report
  • 26wit...
  • Taken for 1 to 6 months
  • April 1, 2017

For Acne "I have been using this product since it was made available without a prescription. If you are going to use it, be sure to read the instructions and warnings. This product has a period of time at the beginning of use that makes your acne worse and then clears it. I went through this process when I started taking Spironolactone, so I knew what to expect and I trusted that it would go away - it did. My skin looks and feels fantastic! I still get an occasional zit here at there - I'm pretty sure it's my fault as I'm a toucher/picker/popper. This is an easy product to add to your routine. Make sure to use it at night and wash off in the morning so you don't have to worry about sunburns. I highly recommend Differin."

8 / 10
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26 Report
  • acneg...
  • Taken for 1 to 6 months
  • January 16, 2014

For Acne "I began to use Epiduo and Differin one month ago. At first I was dissapointed because I had unrealistically high expectations for how fast they would work, but once I got over that and realized it would take time I was fine. I used Velocity moisturizer for the dryness and it didn't work at all sadly, but then I witched to Cetaphil and my skin began to improve because it was no longer too dry. My skin isn't where I want it to be yet, but looking back at older pictures before using the products, I know it's on its way."

8 / 10
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34 Report
  • Anonymous
  • May 28, 2019

For Acne "So I originally started using Differin when I thought my skin care routine wasn’t working any longer. I used this product for over 4 months before finally calling it quits because I feel like it just made my face worse and never got any better. It left my face with really bad discoloration and scaring and the texture of my skin became worse as well. I have since switched back to my previous more natural and more general routine and my face has started clearing up. I was originally advised to try this from my doctor and I was hesitant because I never use products this harsh, and for my skin personally I regret it. I understand you have to go through a purging process with this product but 1. It is not worth the scaring and hyperpigmentation and 2. I don’t think you should have to push through with a product for over 4 months and still not see results. Not only did I not see results but it made my skin significantly worse than when I started the process."

1 / 10
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20 Report
  • Care
  • December 9, 2018

For Acne "This product is awful and has made my life hell for the last 11 weeks. I am a 30 year old with mild comedonal acne on my cheeks. Other products haven't worked for me so after a LOT of research I decided to give Differin a try. I knew I would experience redness, drying and a purging period where my acne would get worse and that its normal. I read hours of reviews where people told me to stick with it until the 12 week mark. I am 3 days away from that mark and my face has NEVER looked or felt this bad in my life. I have painful red pustules popping up every night and continued redness and drying despite constant moisturizing. It's bad enough I have adult acne and that I've been trying to stick it out with this product for 12 weeks but this product has made it SO MUCH WORSE!! I will be sure to tell everyone I know NEVER to use it. I am embarrassed and upset I wasted my time and money for the last 3 months to make my face look worse. Not only that but now I have SCARS all over as well."

1 / 10
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21 Report
  • Cheetos
  • August 16, 2017

For Acne "I needed to share an honest review. I got differin to get rid of these stubborn invisible pimples around my chin. Basically they're clogged pores. They appeared even though I wash my face daily and nightly and exfoliate regularly with expensive products. Then I found differin. I've been on it about 3 weeks now. Although I have gotten breakouts all over, my forehead is it's clearest it's been. The pores on my cheeks are getting smaller and clearer. My nose has practically no problem areas anymore. The invisible pimples/clogged pores are subsiding dramatically. I am getting breakouts in those areas but my face looks radiant anyway."

7 / 10
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24 Report
  • Soqui...
  • Taken for less than 1 month
  • March 20, 2017

For Acne "This stuff is AWESOME. Admittedly it itched like fire for three days until I slacked off and used a good moisturizing cream. But my face is CLEAR for the first time in YEARS. I recommend Carmex to heal the dry flakes and Aveeno after that. If you have another breakout, go back to Differin. I can't recommend this stuff enough. It's worth it to itch and burn for a day or two; it's WORKING. Just deal with it. Thank you, makers of Differin!!! Screw makeup. I'm FREE."

10 / 10
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25 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.