Skip to main content

Adalimumab for Rheumatoid Arthritis User Reviews (Page 5)

Brand names: Humira, Hyrimoz, Hadlima, Amjevita, Simlandi, Idacio, Cyltezo, Yusimry, Hulio, Yuflyma, Abrilada …show all brand names

Adalimumab has an average rating of 6.2 out of 10 from a total of 136 reviews for the treatment of Rheumatoid Arthritis. 54% of reviewers reported a positive experience, while 34% reported a negative experience.

Reviews for Adalimumab

  • Jules
  • December 27, 2021

Humira (adalimumab) "Absolutely unexplainable, horrid, complications however after reading thru their warnings and drug interactions the experiences have everything to do with my prescribing rheumatologist being negligent and not the drug itself. I had many very severe side effects because despite fully knowing other conditions I was on, and even some meds with moderate interaction this should never have even been considered an even possible treatment for me. None of this was disclosed to me with the exception that I’d be more prone to infections however while it was made clear it really wasn’t explained well or as possibly serious as it could be. The one thing that had prompted me to even question my now fired rheumatologists was by using the drugs.com app I keep track of all my meds in and when I entered humira immediately a major health hazard indicated not just one warning but two. Both of which I know they were more than aware of. Coupled with the fact they were also negligent with my first medication."

3 / 10
Was this helpful?YesNo
11 Report
  • JEC
  • Taken for less than 1 month
  • December 22, 2020

Humira (adalimumab) "Humira was not safe for me. Was on methotrexate, but did not control RA well and kept having to have joint replacements. So prescribed Humira, first inection, was okay, did not see any effect, but was told it had to build up. Second injection the next week. The next morning I woke up in trouble! TERRIBLE..rash, facial mask, hives/itching, sores in mouth and throat /eyes. Taken off Humira and told I had a "lupus like" syndrome. Was on steroids for months as it stayed in my system for three months before the lupus episode was over. Humira said once it was out of my system, it would be okay (still get hives off and on). I believe it is likely, now reading literature, that PEG (those lipid nanoparticles) in the injection might have been a cause, but no one knows for sure. BAD drug in my case."

1 / 10
Was this helpful?YesNo
14 Report
  • C-C-1...
  • June 23, 2009

Humira (adalimumab) "I have taken Humira for the past 3 years for Rheumatoid Arthritis and recently we discovered it is also useful for Crohn's disease (which I also have). It does work, but unfortunately I get recurrent sinus infections and have to stop taking the drug while on antibiotics. I have also had an accident at work and have had some surgeries. I've had to interrupt taking the drug due to the surgeries as well (bone fusions). It takes a couple of months to get in your system, but as soon as it does (if you can stay healthy and infection free) it is wonderful. My only concern is the cost and the long term side effects. "

8 / 10
Was this helpful?YesNo
42 Report

Frequently asked questions

  • Kathy
  • Taken for 10 years or more
  • February 16, 2022

Humira (adalimumab) "I have been on Humira since 2007, 14 years and 4 months. It took over 2 years for me to be diagnosed with RA. I went from a jogger, hiker, waterskier to someone who could barely walk from my car into my office building, needed both hands to turn my car key in the ignition due to pain, swollen and painful fingers and feet. Felt like I hardly had a life. After 6 months on Methotrexate, my doctor put me on Humira. Within a few months I was back to running, hiking in the mountains, and water-skiing- I had my life back! I am rarely ill, and have only had one bad sinus infection in the years on Humira. It's worked very well for me."

10 / 10
Was this helpful?YesNo
10 Report
  • trave...
  • Taken for less than 1 month
  • December 3, 2017

Humira (adalimumab) "The drug did not work for me. I felt I was about to have a heart attack. I thought I was going to die. I was ready to call 911. I didn't realize it could have such an adverse effect on you. The doctor prescribed another drug which worked much better without giving me the feeling of an oncoming heart attack."

4 / 10
Was this helpful?YesNo
21 Report

Are you taking this medicine?

  • Tina
  • April 27, 2017

Humira (adalimumab) "I am on plaqunil and the disease was progressing. My dr. (Whom I respect and value) recommended going on Humira. I gave myself the first injection and thought I had gotten my life back. I felt better almost instantly. Unfortunately eleven days later, I had a huge allergic reaction at the site of the injection and my entire body (head to toe) was covered in hives. I was in pain and very itchy for days. I had to discontinue the use of humira immediately and was put on steroids to calm everything down."

1 / 10
Was this helpful?YesNo
21 Report
  • Anonymous
  • Taken for less than 1 month
  • November 3, 2022

Humira (adalimumab) "I took one dose of Humira via injection approximately 2 weeks ago. Within an hour of taking it, I felt agitated for no reason. Over the next few days, I had a full-blown psychotic episode. Never had I ever been diagnosed with Bipolar. As the weekend progressed and feeling absolutely out of control, angry, agitated and tearful, I sought the help of a psychiatrist. She immediately diagnosed me with Bipolar 2 and put me on a mood stabilizer. Now it’s possible that it had nothing to do with the Humira. I’ll never know. But I also won’t take another Humira injection. I just hope I find some relief at this point."

1 / 10
Was this helpful?YesNo
7 Report

More FAQ

  • Angie...
  • June 1, 2015

Humira (adalimumab) "In response to Rick. I started Humira had good results. Then needed to come off it because I injured tendons in my foot. When I restarted Humira, I have not achieved the same results. My joints are red, swelled, and remain in a lot of pain."

4 / 10
Was this helpful?YesNo
25 Report
  • Dizzy...
  • June 15, 2010

Humira (adalimumab) "I have been taking Humira for three months. In the beginning my pain worsened and I got one sinus infection after another. Now I seldom have infections, I think I am more careful.The pain in my hands and feet are much improved, and my elbows and shoulders are a little better. I also have Fibromyalgia so it's hard to distinguish what pain is from what. This week I am getting waves of dizziness that lasts for several hours at a time. I also have what feels like a tennis ball implanted in the back base of my skull. At least my hands and feet warm up quicker in the morning."

8 / 10
Was this helpful?YesNo
34 Report
  • Thorn...
  • Taken for 6 months to 1 year
  • October 24, 2022

Humira (adalimumab) "I tried Humira and my knees got worse. The swelling would come and go especially when I ate high fat, but when I took Humira they stayed inflamed and would not bend. Sure enough after it was out of my system my knees started to straighten out, thank goodness. Low-fat and really nutritious diet with exercise like walking or stationery bike made a huge improvement. You have to keep the joints moving even if it hurts , if you can only move a little then move a little,THEN ADD to it and keep moving and make a plan. You can heal, low-fat , no oil, whole food and EXERCISE! God bless you!"

1 / 10
Was this helpful?YesNo
7 Report
  • Ashbu...
  • May 5, 2016

Humira (adalimumab) "Using for a bout a year a fight to get it due to the cost. It's swings and roundabouts and at least I can work now but think I have become more argumentative. I think if I was a bit older I would not take it. Any one looking to take it don't let anyone put you off its different for everyone. P.S when my consultant said one of the side effects was hair loss think she was joking with me because last time I had a hair cut was in the 90's!"

5 / 10
Was this helpful?YesNo
21 Report
  • Ndn
  • September 19, 2016

Humira (adalimumab) "I have severe RA plus Psoriatic Arthritis plus Asthma plus osteoarthritis plus osteoporosis and I just turned 60. I have severe allergies to anti inflammatories and have had my RA for 30 years. Right now I am on Humara ( can't take methotrexate) and have been for 10 years. Humara really helped at one time but just doesn't work for me anymore. I am in an intense flair that just won't stop we tried Xeljan but my sensitive stomach said no more. I was glad to use the Humara even if I did hold my breath when it came to side effects, nothing major happened but I miss my thick hair."

8 / 10
Was this helpful?YesNo
19 Report
  • Megpalm
  • Taken for 1 to 6 months
  • March 16, 2021

Humira (adalimumab) "Worked fantastic for my RA, but at only 23 there was no other reason besides this medication for sending me to the hospital for diverticulitis. Some doctors are sure that it was caused by the medication while my rheumatologist doesn’t think so. However I am still being switched to Cimzia."

5 / 10
Was this helpful?YesNo
10 Report
  • Cindb
  • Taken for 2 to 5 years
  • October 23, 2022

Humira (adalimumab) "After 3 years of Humira for RA, and doing well I developed plaques on my legs and body! My head, arms etc. my gums turned bright red and bled while on it. After a biopsy on my leg it turned out to be a rare side effect of Humira . After I stopped the drug, the plaques went away and my gums returned to normal . No more bleeding . I can’t believe it took my docs so long to figure it out."

3 / 10
Was this helpful?YesNo
4 Report
  • GTH
  • Taken for 2 to 5 years
  • September 20, 2023

Humira (adalimumab) "Outstanding results with Humira. My symptoms with rheumatoid arthritis were debilitating. I had issues dressing, showering, etc. Methotrexate alone did not have any effect. Humira caused an immediate suppression of symptoms and within a month or so I was back to being ~normal. My rheumatologist was surprised, as he thought I may be a lifetime chronic pain case. I have been using Humira for just over 2 years now and I have no notable side effects. I use 1 40ml pen every other week."

10 / 10
Was this helpful?YesNo
2 Report
  • sduseau
  • Taken for 5 to 10 years
  • August 22, 2022

"I am a 57 y.o. male and have been treated for arthritis for 20 years. I have been on many treatments and medications. Most of them gave me moderate relief for awhile, but never quite did the job. Finally my doctor asked if I would consider a biologic. She gave me lots of information and left me to think on it for 3 months. I decided to try Humira. It was a game changer for me. I have not had a flare up in the 7 years I've been on it. And with no side effects. It has slowed down the progression dramatically. I have had to have both MTPJ's fused, but that damage was done long before starting the Humira. Different drugs react differently with different people. I am fortunate enough to have tolerated all of the medications I've tried, except for Methotrexate."

10 / 10
Was this helpful?YesNo
2 Report
  • Nan
  • Taken for 6 months to 1 year
  • July 21, 2022

Humira (adalimumab) "I have been on Humira for 9-12 months and have received excellent results. However, if your Humira Pen misfires and this happened to me three times, the company will do everything they can to blame the patient. I was given every excuse known to man for them to not replace it. They even said since I took the Humira pen out of the refrigerator the night before my injection that I had it out too long. When I read the information on the box out loud to them that it can be out for 14 days and still be used, they got off the phone and said they would have to call me back tomorrow. The next day, they then said, when is your next delivery of medication coming? I told them I just ordered a new one and it would be here in the next day. Their response was, well since you are getting the medication tomorrow we are not going to replace the three misfired Humira pens. Sooo they do not stand by their product when it misfires. I was out over $400 because the three pens did not dispense medication!!!!"

9 / 10
Was this helpful?YesNo
2 Report
  • Doris...
  • January 24, 2022

Humira (adalimumab) "Today is the first time that I have had a side effect. I've been on it 5 months for RA I have a rash at the injection sight, and swelling burns a little too, just like a bee sting. But this doesn't bother me. I think I might not have left it out of refrig long enough, not stopping it for anything..Helps with my stiffness."

10 / 10
Was this helpful?YesNo
2 Report
  • Endle...
  • Taken for 1 to 6 months
  • September 16, 2019

"Was taken off Humira ASAP when it was discovered I had massive FUNGUS growing & living in my Sinuses! Had to have (FESS) - Bilateral Functional Sinus Surgery! With General Anesthesia and the whole Surgery experience. Great! Been on so many biologicals and none work or cause more harm than good! Currently my DR assured me that bringing out the big guns (IV Infusion of Actemra) would finally end my endless everyday flares going on 10 months! So far after 3 months of Infusions, STILL everyday flaring. I do know that after taking all these biologicals I need to now take high blood pressure medication & also Lasix from water retention! Never had to take all this extra med before biologicals! The only thing that helps the painful flares in my wrist, & shoulders is the dreaded prednisone! I think there is no treatment out there for me."

Was this helpful?YesNo
2 Report
  • Ann
  • June 9, 2009

"I have had arthritis since I was 13. I am now 24. This is the first time since taking multiple medications that I have noticed a significant improvement. I have rated 7/10 with the only issues being the pain of the injection. After being on the drug for two months I have regained complete flexibility in my knees. I still find it difficult to kneel and bend. Hopefully this will come in time but a definite positive improvement so far. Just wish I'd had it earlier."

7 / 10
Was this helpful?YesNo
1 Report
  • Tam
  • Taken for 1 to 6 months
  • May 5, 2024

"Been on adalimumab since December 2023. I got positive RA and PBC with autoimmune hepatitis. Was on steroids but with this medication, some swellings have gone down. Still waiting for it to kick in and work properly."

7 / 10
Was this helpful?YesNo
0 Report
  • Rebecca
  • April 3, 2018

Humira (adalimumab) "My Dad took this medicine and he actually died. I know you won't publish this. "

1 / 10
Was this helpful?YesNo
78 Report
  • Hard...
  • Taken for 5 to 10 years
  • August 6, 2016

Humira (adalimumab) "I've had JRA since I was 2 years old. I started Humira 5 years ago. Worked great. Called it my miracle drug. Just this week I was diagnosed with Lymphoma. I suggest staying away from this product."

1 / 10
Was this helpful?YesNo
60 Report
  • MsMonie
  • January 21, 2015

Humira (adalimumab) "Not completely pain free and stiff joint free. But the fatigue is awful. 5 inj so far, can sleep all day if my family didn't need me. Very lethargic and drained."

5 / 10
Was this helpful?YesNo
65 Report
  • Anonymous
  • January 9, 2012

Humira (adalimumab) "This medicine has enabled me to continue working and living a more normal lifestyle."

10 / 10
Was this helpful?YesNo
74 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

Learn more about Rheumatoid Arthritis

Care guides

Symptoms and treatments

Medicine.com guides (external)