Generic name: Prednisolone Orally Disintegrating Tablets [ pred-NISS-oh-lone ]
Brand name: Orapred ODT
Drug class: Glucocorticoids

Medically reviewed by Drugs.com. Last updated on May 7, 2024.

Uses of Prednisolone Orally Disintegrating Tablets:

• It is used for many health problems like allergy signs, asthma, adrenal gland problems, blood problems, skin rashes, or swelling problems. This is not a list of all health problems that this medicine (prednisolone orally disintegrating tablets) may be used for. Talk with the doctor.

What do I need to tell my doctor BEFORE I take Prednisolone Orally Disintegrating Tablets?

• If you are allergic to this medicine (prednisolone orally disintegrating tablets); any part of this medicine (prednisolone orally disintegrating tablets); or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
• If you have a herpes infection of the eye.
• If you have any of these health problems: A fungal infection or malaria infection in the brain.
• If you have nerve problems in the eye.

This is not a list of all drugs or health problems that interact with this medicine (prednisolone orally disintegrating tablets).

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this medicine (prednisolone orally disintegrating tablets) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Prednisolone Orally Disintegrating Tablets?

• Tell all of your health care providers that you take this medicine (prednisolone orally disintegrating tablets). This includes your doctors, nurses, pharmacists, and dentists.
• Have blood work checked as you have been told by the doctor. Talk with the doctor.
• This medicine may affect allergy skin tests. Be sure your doctor and lab workers know you take this medicine (prednisolone orally disintegrating tablets).
• Do not stop taking this medicine (prednisolone orally disintegrating tablets) all of a sudden without calling your doctor. You may have a greater risk of signs of withdrawal. If you need to stop this medicine (prednisolone orally disintegrating tablets), you will want to slowly stop it as ordered by your doctor.
• You may have more chance of getting an infection. Wash hands often. Stay away from people with infections, colds, or flu.
• Call your doctor right away if you have any signs of infection like fever, chills, flu-like signs, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or a wound that will not heal.
• Chickenpox and measles can be very bad or even deadly in some people taking steroid drugs like this medicine (prednisolone orally disintegrating tablets). Avoid being near anyone with chickenpox or measles if you have not had these health problems before. If you have been exposed to chickenpox or measles, talk with your doctor.
• This medicine may lower how much natural steroid is in your body. If you have a fever, an infection, surgery, or you are hurt, talk with your doctor. You may need extra doses of oral steroids. These extra steroids will help your body deal with these stresses. Carry a warning card saying that there may be times when you need extra steroids.
• High blood pressure has happened with drugs like this one. Have your blood pressure checked as you have been told by your doctor.
• Long-term use may raise the chance of cataracts or glaucoma. Talk with the doctor.
• Have your eye pressure checked if you are on this medicine (prednisolone orally disintegrating tablets) for a long time. Talk with your doctor.
• This medicine may cause weak bones (osteoporosis) with long-term use. Talk with your doctor to see if you have a higher chance of weak bones or if you have any questions.
• Have a bone density test as you have been told by your doctor. Talk with your doctor.
• Talk with your doctor before getting any vaccines. Use of some vaccines with this medicine (prednisolone orally disintegrating tablets) may either raise the chance of an infection or make the vaccine not work as well.
• If you have high blood sugar (diabetes), you will need to watch your blood sugar closely.
• Talk with your doctor before you drink alcohol.
• If you are 65 or older, use this medicine (prednisolone orally disintegrating tablets) with care. You could have more side effects.
• This medicine may affect growth in children and teens in some cases. They may need regular growth checks. Talk with the doctor.
• Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. You will need to talk about the benefits and risks to you and the baby.
• If you used this medicine (prednisolone orally disintegrating tablets) when you were pregnant, tell your baby's doctor.

How is this medicine (Prednisolone Orally Disintegrating Tablets) best taken?

Use this medicine (prednisolone orally disintegrating tablets) as ordered by your doctor. Read all information given to you. Follow all instructions closely.

• Take in the morning if taking once a day.
• Take with food.
• Keep taking this medicine (prednisolone orally disintegrating tablets) as you have been told by your doctor or other health care provider, even if you feel well.
• You may need to lower how much salt is in your diet and take extra potassium. Talk with your doctor.
• Tell your doctor if you have missed a dose or recently stopped this medicine (prednisolone orally disintegrating tablets) and you feel very tired, weak, or shaky, or have a fast heartbeat, confusion, sweating, or dizziness.
• Do not take this medicine (prednisolone orally disintegrating tablets) out of the blister pack until you are ready to take it. Take this medicine (prednisolone orally disintegrating tablets) right away after opening the blister pack. Do not store the removed drug for future use.
• Do not push the tablet out of the foil when opening. Use dry hands to take it from the foil. Place on your tongue and let it dissolve. Water is not needed. Do not swallow it whole. Do not chew, break, or crush it.

What do I do if I miss a dose?

• Take a missed dose as soon as you think about it, with food.
• If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
• Do not take 2 doses at the same time or extra doses.

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What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

• Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
• Signs of high blood sugar like confusion, feeling sleepy, more thirst, more hungry, passing urine more often, flushing, fast breathing, or breath that smells like fruit.
• Signs of Cushing's disease like weight gain in the upper back or belly, moon face, very bad headache, or slow healing.
• Signs of a weak adrenal gland like a very bad upset stomach or throwing up, very bad dizziness or passing out, muscle weakness, feeling very tired, mood changes, not hungry, or weight loss.
• Signs of low potassium levels like muscle pain or weakness, muscle cramps, or a heartbeat that does not feel normal.
• Signs of high blood pressure like very bad headache or dizziness, passing out, or change in eyesight.
• Signs of a pancreas problem (pancreatitis) like very bad stomach pain, very bad back pain, or very bad upset stomach or throwing up.
• Skin changes (pimples, stretch marks, slow healing, hair growth).
• Chest pain or pressure.
• Fast, slow, or abnormal heartbeat.
• Swelling, warmth, numbness, change of color, or pain in a leg or arm.
• Period (menstrual) changes.
• Bone or joint pain.
• Change in eyesight.
• Mental, mood, or behavior changes that are new or worse.
• Seizures.
• A burning, numbness, or tingling feeling that is not normal.
• Any unexplained bruising or bleeding.
• Swelling of belly.
• Black, tarry, or bloody stools.
• Throwing up blood or throw up that looks like coffee grounds.
• Muscle weakness that is new or worse.
• This medicine may cause you to swell or keep fluid in your body. Tell your doctor if you have swelling, weight gain, or trouble breathing.

What are some other side effects of Prednisolone Orally Disintegrating Tablets?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

• Upset stomach.
• More hungry.
• Weight gain.
• Trouble sleeping.
• Restlessness.
• Sweating a lot.
• Headache.
• Feeling tired or weak.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Prednisolone Orally Disintegrating Tablets?

• Store at room temperature in a dry place. Do not store in a bathroom.
• Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
• Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.

Consumer Information Use and Disclaimer

• If your symptoms or health problems do not get better or if they become worse, call your doctor.
• Do not share your drugs with others and do not take anyone else's drugs.
• Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about this medicine (prednisolone orally disintegrating tablets), please talk with your doctor, nurse, pharmacist, or other health care provider.
• If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Frequently asked questions

• Prednisone vs Prednisolone - What's the difference?
• Is prednisolone best taken in the morning and why?

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer