I want the timeline. I have colonoscopy at 8 am. Suprep has to be taken 16 oz first followed by 32?

I just finished my 2nd colonoscopy; last one was in 2012. Very good question from 6 years ago and still relevant. My suggestion; if you have an early morning appointment (10:00 am for mine) is to start the split dose treatment earlier on your first fasting day and do not eat anything on your fasting day except broth, tea coffee. I was told to start my first split dose at 5:00 pm Thursday afternoon. It took 4 hours for diarrhea to finally stop. I moved up my 2nd dose to 10pm instead of 3:00 am Friday morning. Everything worked out fine, but ask your dr. For specific time line good luck!

I think each person reactions are varied. I took my first does at 5:20pm, I did as described. First bottle with 16oz of water, followed by two more classes of water 16oz within the first hour. So far, no results. Its 9:30pm. I have drank 2 more classes of water to help out. All I feel is bloated.

My recent colonoscopy was 11:45 am. I took the first dose of Suprep at 4pm the day before... and then at 4 am the next morning. It started working within minutes... not like the old stuff. No cramping... the bathroom part was the easiest, actually, of all the colonoscopies I have had with other meds. Drinking it was another matter...
I did actually get a bit of rest throughout the night... which was also different.
I hope everything went well for you... :-)

Ok. Your colonoscopy is at 8am. You need the prep and water followed 10-12 hours later by another dose of prep and water. I would say to start the first prep at 8am the day before and 10-12 hours later would be 6-8pm to do the next dose of prep and water. Sleep as much as you can the night before. The first dose of prep should begin clearing you out during the daytime hours. The second dose of prep should go through pretty quick if you are fairly cleaned out from the first round. It is just an "insurance" that you are good and clean. You may be up having some stools during the night but I think it will be only on the first few hours so you might want to start the second prep at 6pm so you get a few hours to let the second dose of prep work its way through before you go to bed that way you can get some sleep. Good Luck!